Does botulinum toxin injection in parotid glands interfere with the swallowing dynamics of Parkinson's disease patients?

Detalhes bibliográficos
Autor(a) principal: Nóbrega, Ana Caline
Data de Publicação: 2009
Outros Autores: Rodrigues, Bernardo, Melo, Ailton de Souza
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/13510
Resumo: Texto completo: acesso restrito. p. 430-432
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spelling Nóbrega, Ana CalineRodrigues, BernardoMelo, Ailton de SouzaNóbrega, Ana CalineRodrigues, BernardoMelo, Ailton de Souza2013-11-03T13:38:41Z20090303-8467http://repositorio.ufba.br/ri/handle/ri/13510v. 111, n. 5Texto completo: acesso restrito. p. 430-432Background: During recent years, sialorrhea in Parkinson's disease (PD) has been treated with botulinum toxin type A (BT-A); however, there are no data describing its effects on swallowing dynamics in this group of patients. Objective: To investigate whether injection of BT-A into the parotid glands interferes with the oropharyngeal swallowing dynamics of patients with Parkinson's disease. Methods: Sixteen patients with diurnal sialorrhea were selected and evaluated during the “on” period by a standardized questionnaire and swallowing videofluoroscopy before and 30 days after ultrasound-guided BT-A injection into the parotid glands. Results: A decrease in sialorrhea was observed in all studied patients. Silent laryngeal penetration was observed in three patients, and silent aspiration was observed in two of them. There were no changes in swallowing dynamics when comparing patients before and after BT-A parotid injection (p = 1), suggesting similar levels of dysphagia in the two measurements. Conclusion: BT-A injection into parotid glands does not interfere with the oropharyngeal swallowing dynamics of PD patients.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-10-08T16:15:56Z No. of bitstreams: 1 1-s2.0-S0303846708004289-main.pdf: 137976 bytes, checksum: a98879eaae5f33fbc39eab3def1630fa (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-11-03T13:38:40Z (GMT) No. of bitstreams: 1 1-s2.0-S0303846708004289-main.pdf: 137976 bytes, checksum: a98879eaae5f33fbc39eab3def1630fa (MD5)Made available in DSpace on 2013-11-03T13:38:41Z (GMT). No. of bitstreams: 1 1-s2.0-S0303846708004289-main.pdf: 137976 bytes, checksum: a98879eaae5f33fbc39eab3def1630fa (MD5) Previous issue date: 2009http://dx.doi.org/10.1016/j.clineuro.2008.12.007reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAParkinson's diseaseDysphagiaSwallowing disordersSilent aspirationSialorrheaBotulinum toxinDoes botulinum toxin injection in parotid glands interfere with the swallowing dynamics of Parkinson's disease patients?Clinical Neurology and Neurosurgeryinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINAL1-s2.0-S0303846708004289-main.pdf1-s2.0-S0303846708004289-main.pdfapplication/pdf137976https://repositorio.ufba.br/bitstream/ri/13510/1/1-s2.0-S0303846708004289-main.pdfa98879eaae5f33fbc39eab3def1630faMD51LICENSElicense.txtlicense.txttext/plain1365https://repositorio.ufba.br/bitstream/ri/13510/2/license.txt5371a150bdc863f78dcf39281543bd86MD52TEXT1-s2.0-S0303846708004289-main.pdf.txt1-s2.0-S0303846708004289-main.pdf.txtExtracted texttext/plain14239https://repositorio.ufba.br/bitstream/ri/13510/3/1-s2.0-S0303846708004289-main.pdf.txtfc7fd9e4caf98496462c5aaeb3c9944bMD53ri/135102022-07-05 14:03:20.475oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:20Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Does botulinum toxin injection in parotid glands interfere with the swallowing dynamics of Parkinson's disease patients?
dc.title.alternative.pt_BR.fl_str_mv Clinical Neurology and Neurosurgery
title Does botulinum toxin injection in parotid glands interfere with the swallowing dynamics of Parkinson's disease patients?
spellingShingle Does botulinum toxin injection in parotid glands interfere with the swallowing dynamics of Parkinson's disease patients?
Nóbrega, Ana Caline
Parkinson's disease
Dysphagia
Swallowing disorders
Silent aspiration
Sialorrhea
Botulinum toxin
title_short Does botulinum toxin injection in parotid glands interfere with the swallowing dynamics of Parkinson's disease patients?
title_full Does botulinum toxin injection in parotid glands interfere with the swallowing dynamics of Parkinson's disease patients?
title_fullStr Does botulinum toxin injection in parotid glands interfere with the swallowing dynamics of Parkinson's disease patients?
title_full_unstemmed Does botulinum toxin injection in parotid glands interfere with the swallowing dynamics of Parkinson's disease patients?
title_sort Does botulinum toxin injection in parotid glands interfere with the swallowing dynamics of Parkinson's disease patients?
author Nóbrega, Ana Caline
author_facet Nóbrega, Ana Caline
Rodrigues, Bernardo
Melo, Ailton de Souza
author_role author
author2 Rodrigues, Bernardo
Melo, Ailton de Souza
author2_role author
author
dc.contributor.author.fl_str_mv Nóbrega, Ana Caline
Rodrigues, Bernardo
Melo, Ailton de Souza
Nóbrega, Ana Caline
Rodrigues, Bernardo
Melo, Ailton de Souza
dc.subject.por.fl_str_mv Parkinson's disease
Dysphagia
Swallowing disorders
Silent aspiration
Sialorrhea
Botulinum toxin
topic Parkinson's disease
Dysphagia
Swallowing disorders
Silent aspiration
Sialorrhea
Botulinum toxin
description Texto completo: acesso restrito. p. 430-432
publishDate 2009
dc.date.issued.fl_str_mv 2009
dc.date.accessioned.fl_str_mv 2013-11-03T13:38:41Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/13510
dc.identifier.issn.none.fl_str_mv 0303-8467
dc.identifier.number.pt_BR.fl_str_mv v. 111, n. 5
identifier_str_mv 0303-8467
v. 111, n. 5
url http://repositorio.ufba.br/ri/handle/ri/13510
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/j.clineuro.2008.12.007
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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