Nonalcoholic fatty liver disease in asymptomatic Brazilian adolescents

Detalhes bibliográficos
Autor(a) principal: Rocha, Raquel
Data de Publicação: 2009
Outros Autores: Cotrim, Helma Pinchemel, Bitencourt, Almir Galvão Vieira, Barbosa, Daniel Batista Valente, Santos, Adimeia Souza, Almeida, Alessandro de Moura, Cunha, Bruno, Guimarães, Isabel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/5885
Resumo: Acesso restrito: Texto completo. p. 473-477
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spelling Rocha, RaquelCotrim, Helma PinchemelBitencourt, Almir Galvão VieiraBarbosa, Daniel Batista ValenteSantos, Adimeia SouzaAlmeida, Alessandro de MouraCunha, BrunoGuimarães, IsabelRocha, RaquelCotrim, Helma PinchemelBitencourt, Almir Galvão VieiraBarbosa, Daniel Batista ValenteSantos, Adimeia SouzaAlmeida, Alessandro de MouraCunha, BrunoGuimarães, Isabel2012-05-16T18:29:46Z20090944-1174http://www.repositorio.ufba.br/ri/handle/ri/5885v. 15, n. 4Acesso restrito: Texto completo. p. 473-477AIM: To evaluate the prevalence and clinical characteristics of Nonalcoholic fatty liver disease (NAFLD) among asymptomatic Brazilian adolescents. METHODS: Transversal observational study included asymptomatic adolescents with central obesity from private and public schools in Salvador-Bahia, northeastern Brazil. The children answered a questionnaire that included age, gender, race, and medical history, and were submitted to a complete physical exam and abdominal ultrasound. Biochemical exams included: ALT, AST, GGT, C reactive protein (CRP), fasting glucose, insulin, cholesterol and triglycerides. Criteria for NAFLD included: the presence of steatosis in ultrasound and/or high level of ALT, negative or occasional historic of intake of alcohol (≤ 140 g/wk), negative investigation for hepatitis A, B, C, auto-immune hepatitis, Wilson disease and hemochromatosis. RESULTS: From October, 2005 to October, 2006, the study included 1801 subjects between 11 and 18 years of age and a mean age of 13.7 ± 2.0 years. One hundred ninety-nine had central obesity. The prevalence of NAFLD was 2.3%, most of whom were male and white. Insulin resistance (IR) was observed in 22.9% of them and had positive correlations with ALT and GGT (P < 0.05). Elevated CRP was observed in 6.9% of the cases; however, it was not associated with WC, IR or liver enzymes. CONCLUSION: The prevalence of NAFLD in Brazilian adolescents was low. The ethnicity may have influence this frequency in the population studied, which had a large proportion of African descendents.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-05-16T18:29:46Z No. of bitstreams: 1 __www.springerlink.com_c...k2464146086630h7_fulltext.pdf: 743045 bytes, checksum: 00ad8b194944a2654516647ff7dbcab9 (MD5)Made available in DSpace on 2012-05-16T18:29:46Z (GMT). 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dc.title.pt_BR.fl_str_mv Nonalcoholic fatty liver disease in asymptomatic Brazilian adolescents
dc.title.alternative.pt_BR.fl_str_mv World Journal of Gastroenterology
title Nonalcoholic fatty liver disease in asymptomatic Brazilian adolescents
spellingShingle Nonalcoholic fatty liver disease in asymptomatic Brazilian adolescents
Rocha, Raquel
Nonalcoholic fatty liver disease
Insulin resistance
Central obesity
Ethnicity
Adolescents
title_short Nonalcoholic fatty liver disease in asymptomatic Brazilian adolescents
title_full Nonalcoholic fatty liver disease in asymptomatic Brazilian adolescents
title_fullStr Nonalcoholic fatty liver disease in asymptomatic Brazilian adolescents
title_full_unstemmed Nonalcoholic fatty liver disease in asymptomatic Brazilian adolescents
title_sort Nonalcoholic fatty liver disease in asymptomatic Brazilian adolescents
author Rocha, Raquel
author_facet Rocha, Raquel
Cotrim, Helma Pinchemel
Bitencourt, Almir Galvão Vieira
Barbosa, Daniel Batista Valente
Santos, Adimeia Souza
Almeida, Alessandro de Moura
Cunha, Bruno
Guimarães, Isabel
author_role author
author2 Cotrim, Helma Pinchemel
Bitencourt, Almir Galvão Vieira
Barbosa, Daniel Batista Valente
Santos, Adimeia Souza
Almeida, Alessandro de Moura
Cunha, Bruno
Guimarães, Isabel
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Rocha, Raquel
Cotrim, Helma Pinchemel
Bitencourt, Almir Galvão Vieira
Barbosa, Daniel Batista Valente
Santos, Adimeia Souza
Almeida, Alessandro de Moura
Cunha, Bruno
Guimarães, Isabel
Rocha, Raquel
Cotrim, Helma Pinchemel
Bitencourt, Almir Galvão Vieira
Barbosa, Daniel Batista Valente
Santos, Adimeia Souza
Almeida, Alessandro de Moura
Cunha, Bruno
Guimarães, Isabel
dc.subject.por.fl_str_mv Nonalcoholic fatty liver disease
Insulin resistance
Central obesity
Ethnicity
Adolescents
topic Nonalcoholic fatty liver disease
Insulin resistance
Central obesity
Ethnicity
Adolescents
description Acesso restrito: Texto completo. p. 473-477
publishDate 2009
dc.date.issued.fl_str_mv 2009
dc.date.accessioned.fl_str_mv 2012-05-16T18:29:46Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/5885
dc.identifier.issn.none.fl_str_mv 0944-1174
dc.identifier.number.pt_BR.fl_str_mv v. 15, n. 4
identifier_str_mv 0944-1174
v. 15, n. 4
url http://www.repositorio.ufba.br/ri/handle/ri/5885
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http:// dx.doi.org/10.3748/wjg.15.473
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instname_str Universidade Federal da Bahia (UFBA)
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