C-reactive protein and metabolic syndrome in youth: a strong relationship?
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/15926 |
Resumo: | Texto completo: acesso restrito. p. 1094-1098 |
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Oliveira, Antônio Carlos Paula deOliveira, Ana M.Adan, Luís Fernando FernandesOliveira, Nelson Fernandes deSilva, Agnaluce M.Ladeia, Ana Marice TeixeiraOliveira, Antônio Carlos Paula deOliveira, Ana M.Adan, Luís Fernando FernandesOliveira, Nelson Fernandes deSilva, Agnaluce M.Ladeia, Ana Marice Teixeira2014-09-09T15:20:42Z20081930-7381http://repositorio.ufba.br/ri/handle/ri/15926v. 16, n. 5Texto completo: acesso restrito. p. 1094-1098Objective: Metabolic syndrome (MS) is on the rise in youth. As high-sensitivity C-reactive protein (hs-CRP) is associated with cardiovascular/metabolic disorders, we evaluated the association between MS and its components and hs-CRP in a sample of Brazilian overweight and obese youth. Methods and Procedures: A total of 407 students (229 girls, 273 with excessive weight, 11.3 ± 3.2 years) were evaluated. Measurement included BMI, waist circumference (WC), blood pressure, lipids, insulin, and hs-CRP. Excessive weight was defined using BMI z -score; MS by the modified National Cholesterol Education Program—Adult Treatment Panel III. Results: Subjects were classified into two groups: with MS (n = 72) and without (n = 335). hs-CRP means and medians were higher in MS group (1.41 mg/l vs. 1.06 mg/l, P < 0.001; 2.21 mg/l vs. 1.23 mg/l, P < 0.001). Associations between hs-CRP quartiles and insulin resistance (IR) (P < 0.001), MS (P < 0.001), WC (P < 0.000), BMI z-score (P < 0.001), hypertension (P < 0.001), hypertriglyceridemia (P < 0.001), and low HDL-c (P = 0.023) were significant; adjustment of hs-CRP for BMI z-score eliminated the previous association, except for the number of MS components (nMSc) (P < 0.001). Adjusting for homeostasis model assessment method of IR (HOMA-IR) did not eliminate the relation between hs-CRP and MS components. Furthermore, increases in BMI z -score and nMSc were associated with an increased hs-CRP. Excessive weight (odds ratio (OR), 7.9; confidence interval (CI), 4.7–13.4; P = 0.000), hypertension (OR, 2.3; CI, 1.3–4.2; P = 0.003), and hypertriglyceridemia (OR, 2.3; CI, 1.5–3.7; P < 0.001) were independently associated with hs-CRP. Discussion: In youth, hs-CRP is strongly related with MS and its components, and is also determined by the body composition. This association indicates a precocious proinflammatory state.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-12-09T16:31:09Z No. of bitstreams: 1 10.1038-oby.2008.43.pdf: 145065 bytes, checksum: 87aa8f322f39959b352d2d73ba7a8588 (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2014-09-09T15:20:42Z (GMT) No. of bitstreams: 1 10.1038-oby.2008.43.pdf: 145065 bytes, checksum: 87aa8f322f39959b352d2d73ba7a8588 (MD5)Made available in DSpace on 2014-09-09T15:20:42Z (GMT). No. of bitstreams: 1 10.1038-oby.2008.43.pdf: 145065 bytes, checksum: 87aa8f322f39959b352d2d73ba7a8588 (MD5) Previous issue date: 2008http://dx.doi.org/10.1038/oby.2008.43reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAC-reactive protein and metabolic syndrome in youth: a strong relationship?Obesityinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINAL10.1038-oby.2008.43.pdf10.1038-oby.2008.43.pdfapplication/pdf145065https://repositorio.ufba.br/bitstream/ri/15926/1/10.1038-oby.2008.43.pdf87aa8f322f39959b352d2d73ba7a8588MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/15926/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXT10.1038-oby.2008.43.pdf.txt10.1038-oby.2008.43.pdf.txtExtracted texttext/plain29203https://repositorio.ufba.br/bitstream/ri/15926/3/10.1038-oby.2008.43.pdf.txt97bc6ca2af13c46637dac33a326cfe85MD53ri/159262022-07-05 14:03:32.885oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:32Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
C-reactive protein and metabolic syndrome in youth: a strong relationship? |
dc.title.alternative.pt_BR.fl_str_mv |
Obesity |
title |
C-reactive protein and metabolic syndrome in youth: a strong relationship? |
spellingShingle |
C-reactive protein and metabolic syndrome in youth: a strong relationship? Oliveira, Antônio Carlos Paula de |
title_short |
C-reactive protein and metabolic syndrome in youth: a strong relationship? |
title_full |
C-reactive protein and metabolic syndrome in youth: a strong relationship? |
title_fullStr |
C-reactive protein and metabolic syndrome in youth: a strong relationship? |
title_full_unstemmed |
C-reactive protein and metabolic syndrome in youth: a strong relationship? |
title_sort |
C-reactive protein and metabolic syndrome in youth: a strong relationship? |
author |
Oliveira, Antônio Carlos Paula de |
author_facet |
Oliveira, Antônio Carlos Paula de Oliveira, Ana M. Adan, Luís Fernando Fernandes Oliveira, Nelson Fernandes de Silva, Agnaluce M. Ladeia, Ana Marice Teixeira |
author_role |
author |
author2 |
Oliveira, Ana M. Adan, Luís Fernando Fernandes Oliveira, Nelson Fernandes de Silva, Agnaluce M. Ladeia, Ana Marice Teixeira |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Oliveira, Antônio Carlos Paula de Oliveira, Ana M. Adan, Luís Fernando Fernandes Oliveira, Nelson Fernandes de Silva, Agnaluce M. Ladeia, Ana Marice Teixeira Oliveira, Antônio Carlos Paula de Oliveira, Ana M. Adan, Luís Fernando Fernandes Oliveira, Nelson Fernandes de Silva, Agnaluce M. Ladeia, Ana Marice Teixeira |
description |
Texto completo: acesso restrito. p. 1094-1098 |
publishDate |
2008 |
dc.date.issued.fl_str_mv |
2008 |
dc.date.accessioned.fl_str_mv |
2014-09-09T15:20:42Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufba.br/ri/handle/ri/15926 |
dc.identifier.issn.none.fl_str_mv |
1930-7381 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 16, n. 5 |
identifier_str_mv |
1930-7381 v. 16, n. 5 |
url |
http://repositorio.ufba.br/ri/handle/ri/15926 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
dc.source.pt_BR.fl_str_mv |
http://dx.doi.org/10.1038/oby.2008.43 |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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Universidade Federal da Bahia (UFBA) |
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