Bezold–Jarisch reflex in sino-aortic denervated malnourished rats
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/16555 |
Resumo: | Texto completo: acesso restrito. p. 48–53 |
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Bezerra, Vanessa MoraesXavier, Carlos HenriqueMenezes, Rodrigo Cunha Alvim deFontes, Marco Antônio PelikyCardoso, Leonardo MáximoFernandes, Luciano GonçalvesChianca Jr., Deoclécio AlvesBezerra, Vanessa MoraesXavier, Carlos HenriqueMenezes, Rodrigo Cunha Alvim deFontes, Marco Antônio PelikyCardoso, Leonardo MáximoFernandes, Luciano GonçalvesChianca Jr., Deoclécio Alves2014-11-11T18:00:26Z20111566-0702http://repositorio.ufba.br/ri/handle/ri/16555v. 162, n. 1-2Texto completo: acesso restrito. p. 48–53In this study we assessed the role of Bezold–Jarisch reflex (BJR) in the regulation of blood pressure (BP) of malnourished (MN) and control rats (CN) with sino-aortic denervation (SAD). Fischer rats were fed diets containing either 6% (MN) or 15% (CN) protein for 35 days after weaning. These rats underwent sham or SAD and catheterization of femoral artery and vein for BP measurements and drug injection. Phenylbiguanide (PBG 5 μg/kg, i.v.) for activation BJR, produced bradycardia (− 317 ± 22 bpm for CN vs. − 372 ± 16 bpm for MN) and hypotension (− 57 ± 4 mm Hg for CN vs. − 54 ± 6 mm Hg for MN. After SAD, MN rats had reduced hypotensive (− 37 ± 7 mmHg for MN vs. − 82 ± 6 mm Hg for CN) and bradycardic (− 124 ± 17 for MN vs. − 414 ± 20 bpm CN) responses to BJR activation. To evaluate the contribution of the parasympathetic component due to BJR for the fall in BP, methyl atropine bromide, was given between two injections of PBG (5 μg/kg) separated by 10 min each other. Both bradycardic (− 216 ± 21 bpm before and − 4±3 bpm after for CN − 226±43 bpm before and − 9±20 bpm after for MN) and hypotensive (− 42±4 mm Hg before and − 6±1 mm Hg after for CN − 33±9 mm Hg before and − 5±2 mm Hg after for MN) responses were abolished in CN and MN groups. These data indicate that dietary protein malnutrition changes the relation between baroreflex and BJR required for maintenance of the BP during malnourishment.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-03-18T11:42:10Z No. of bitstreams: 1 Vanessa Moraes Bezerra.pdf: 511835 bytes, checksum: 4143996e9f2ee610be05408fda808cfe (MD5)Approved for entry into archive by Alda Lima da Silva (sivalda@ufba.br) on 2014-11-11T18:00:26Z (GMT) No. of bitstreams: 1 Vanessa Moraes Bezerra.pdf: 511835 bytes, checksum: 4143996e9f2ee610be05408fda808cfe (MD5)Made available in DSpace on 2014-11-11T18:00:26Z (GMT). No. of bitstreams: 1 Vanessa Moraes Bezerra.pdf: 511835 bytes, checksum: 4143996e9f2ee610be05408fda808cfe (MD5) Previous issue date: 2011http://dx.doi.org.ez10.periodicos.capes.gov.br/10.1016/j.autneu.2011.03.006reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAProtein malnourishmentBezold–Jarisch reflexSino aortic denervationBezold–Jarisch reflex in sino-aortic denervated malnourished ratsAutonomic Neuroscience: Basic and Clinicalinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengLICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/16555/2/license.txt0d4b811ef71182510d2015daa7c8a900MD52ORIGINALVanessa Moraes Bezerra.pdfVanessa Moraes Bezerra.pdfapplication/pdf511835https://repositorio.ufba.br/bitstream/ri/16555/1/Vanessa%20Moraes%20Bezerra.pdf4143996e9f2ee610be05408fda808cfeMD51TEXTVanessa Moraes Bezerra.pdf.txtVanessa Moraes Bezerra.pdf.txtExtracted texttext/plain32206https://repositorio.ufba.br/bitstream/ri/16555/3/Vanessa%20Moraes%20Bezerra.pdf.txt4cf736abecb311bc55645e25c3d52417MD53ri/165552022-08-08 13:17:38.003oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-08T16:17:38Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Bezold–Jarisch reflex in sino-aortic denervated malnourished rats |
dc.title.alternative.pt_BR.fl_str_mv |
Autonomic Neuroscience: Basic and Clinical |
title |
Bezold–Jarisch reflex in sino-aortic denervated malnourished rats |
spellingShingle |
Bezold–Jarisch reflex in sino-aortic denervated malnourished rats Bezerra, Vanessa Moraes Protein malnourishment Bezold–Jarisch reflex Sino aortic denervation |
title_short |
Bezold–Jarisch reflex in sino-aortic denervated malnourished rats |
title_full |
Bezold–Jarisch reflex in sino-aortic denervated malnourished rats |
title_fullStr |
Bezold–Jarisch reflex in sino-aortic denervated malnourished rats |
title_full_unstemmed |
Bezold–Jarisch reflex in sino-aortic denervated malnourished rats |
title_sort |
Bezold–Jarisch reflex in sino-aortic denervated malnourished rats |
author |
Bezerra, Vanessa Moraes |
author_facet |
Bezerra, Vanessa Moraes Xavier, Carlos Henrique Menezes, Rodrigo Cunha Alvim de Fontes, Marco Antônio Peliky Cardoso, Leonardo Máximo Fernandes, Luciano Gonçalves Chianca Jr., Deoclécio Alves |
author_role |
author |
author2 |
Xavier, Carlos Henrique Menezes, Rodrigo Cunha Alvim de Fontes, Marco Antônio Peliky Cardoso, Leonardo Máximo Fernandes, Luciano Gonçalves Chianca Jr., Deoclécio Alves |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Bezerra, Vanessa Moraes Xavier, Carlos Henrique Menezes, Rodrigo Cunha Alvim de Fontes, Marco Antônio Peliky Cardoso, Leonardo Máximo Fernandes, Luciano Gonçalves Chianca Jr., Deoclécio Alves Bezerra, Vanessa Moraes Xavier, Carlos Henrique Menezes, Rodrigo Cunha Alvim de Fontes, Marco Antônio Peliky Cardoso, Leonardo Máximo Fernandes, Luciano Gonçalves Chianca Jr., Deoclécio Alves |
dc.subject.por.fl_str_mv |
Protein malnourishment Bezold–Jarisch reflex Sino aortic denervation |
topic |
Protein malnourishment Bezold–Jarisch reflex Sino aortic denervation |
description |
Texto completo: acesso restrito. p. 48–53 |
publishDate |
2011 |
dc.date.issued.fl_str_mv |
2011 |
dc.date.accessioned.fl_str_mv |
2014-11-11T18:00:26Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://repositorio.ufba.br/ri/handle/ri/16555 |
dc.identifier.issn.none.fl_str_mv |
1566-0702 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 162, n. 1-2 |
identifier_str_mv |
1566-0702 v. 162, n. 1-2 |
url |
http://repositorio.ufba.br/ri/handle/ri/16555 |
dc.language.iso.fl_str_mv |
eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
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http://dx.doi.org.ez10.periodicos.capes.gov.br/10.1016/j.autneu.2011.03.006 |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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Universidade Federal da Bahia (UFBA) |
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