Bezold–Jarisch reflex in sino-aortic denervated malnourished rats

Detalhes bibliográficos
Autor(a) principal: Bezerra, Vanessa Moraes
Data de Publicação: 2011
Outros Autores: Xavier, Carlos Henrique, Menezes, Rodrigo Cunha Alvim de, Fontes, Marco Antônio Peliky, Cardoso, Leonardo Máximo, Fernandes, Luciano Gonçalves, Chianca Jr., Deoclécio Alves
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/16555
Resumo: Texto completo: acesso restrito. p. 48–53
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spelling Bezerra, Vanessa MoraesXavier, Carlos HenriqueMenezes, Rodrigo Cunha Alvim deFontes, Marco Antônio PelikyCardoso, Leonardo MáximoFernandes, Luciano GonçalvesChianca Jr., Deoclécio AlvesBezerra, Vanessa MoraesXavier, Carlos HenriqueMenezes, Rodrigo Cunha Alvim deFontes, Marco Antônio PelikyCardoso, Leonardo MáximoFernandes, Luciano GonçalvesChianca Jr., Deoclécio Alves2014-11-11T18:00:26Z20111566-0702http://repositorio.ufba.br/ri/handle/ri/16555v. 162, n. 1-2Texto completo: acesso restrito. p. 48–53In this study we assessed the role of Bezold–Jarisch reflex (BJR) in the regulation of blood pressure (BP) of malnourished (MN) and control rats (CN) with sino-aortic denervation (SAD). Fischer rats were fed diets containing either 6% (MN) or 15% (CN) protein for 35 days after weaning. These rats underwent sham or SAD and catheterization of femoral artery and vein for BP measurements and drug injection. Phenylbiguanide (PBG 5 μg/kg, i.v.) for activation BJR, produced bradycardia (− 317 ± 22 bpm for CN vs. − 372 ± 16 bpm for MN) and hypotension (− 57 ± 4 mm Hg for CN vs. − 54 ± 6 mm Hg for MN. After SAD, MN rats had reduced hypotensive (− 37 ± 7 mmHg for MN vs. − 82 ± 6 mm Hg for CN) and bradycardic (− 124 ± 17 for MN vs. − 414 ± 20 bpm CN) responses to BJR activation. To evaluate the contribution of the parasympathetic component due to BJR for the fall in BP, methyl atropine bromide, was given between two injections of PBG (5 μg/kg) separated by 10 min each other. Both bradycardic (− 216 ± 21 bpm before and − 4±3 bpm after for CN − 226±43 bpm before and − 9±20 bpm after for MN) and hypotensive (− 42±4 mm Hg before and − 6±1 mm Hg after for CN − 33±9 mm Hg before and − 5±2 mm Hg after for MN) responses were abolished in CN and MN groups. These data indicate that dietary protein malnutrition changes the relation between baroreflex and BJR required for maintenance of the BP during malnourishment.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-03-18T11:42:10Z No. of bitstreams: 1 Vanessa Moraes Bezerra.pdf: 511835 bytes, checksum: 4143996e9f2ee610be05408fda808cfe (MD5)Approved for entry into archive by Alda Lima da Silva (sivalda@ufba.br) on 2014-11-11T18:00:26Z (GMT) No. of bitstreams: 1 Vanessa Moraes Bezerra.pdf: 511835 bytes, checksum: 4143996e9f2ee610be05408fda808cfe (MD5)Made available in DSpace on 2014-11-11T18:00:26Z (GMT). No. of bitstreams: 1 Vanessa Moraes Bezerra.pdf: 511835 bytes, checksum: 4143996e9f2ee610be05408fda808cfe (MD5) Previous issue date: 2011http://dx.doi.org.ez10.periodicos.capes.gov.br/10.1016/j.autneu.2011.03.006reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAProtein malnourishmentBezold–Jarisch reflexSino aortic denervationBezold–Jarisch reflex in sino-aortic denervated malnourished ratsAutonomic Neuroscience: Basic and Clinicalinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengLICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/16555/2/license.txt0d4b811ef71182510d2015daa7c8a900MD52ORIGINALVanessa Moraes Bezerra.pdfVanessa Moraes Bezerra.pdfapplication/pdf511835https://repositorio.ufba.br/bitstream/ri/16555/1/Vanessa%20Moraes%20Bezerra.pdf4143996e9f2ee610be05408fda808cfeMD51TEXTVanessa Moraes Bezerra.pdf.txtVanessa Moraes Bezerra.pdf.txtExtracted texttext/plain32206https://repositorio.ufba.br/bitstream/ri/16555/3/Vanessa%20Moraes%20Bezerra.pdf.txt4cf736abecb311bc55645e25c3d52417MD53ri/165552022-08-08 13:17:38.003oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-08T16:17:38Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Bezold–Jarisch reflex in sino-aortic denervated malnourished rats
dc.title.alternative.pt_BR.fl_str_mv Autonomic Neuroscience: Basic and Clinical
title Bezold–Jarisch reflex in sino-aortic denervated malnourished rats
spellingShingle Bezold–Jarisch reflex in sino-aortic denervated malnourished rats
Bezerra, Vanessa Moraes
Protein malnourishment
Bezold–Jarisch reflex
Sino aortic denervation
title_short Bezold–Jarisch reflex in sino-aortic denervated malnourished rats
title_full Bezold–Jarisch reflex in sino-aortic denervated malnourished rats
title_fullStr Bezold–Jarisch reflex in sino-aortic denervated malnourished rats
title_full_unstemmed Bezold–Jarisch reflex in sino-aortic denervated malnourished rats
title_sort Bezold–Jarisch reflex in sino-aortic denervated malnourished rats
author Bezerra, Vanessa Moraes
author_facet Bezerra, Vanessa Moraes
Xavier, Carlos Henrique
Menezes, Rodrigo Cunha Alvim de
Fontes, Marco Antônio Peliky
Cardoso, Leonardo Máximo
Fernandes, Luciano Gonçalves
Chianca Jr., Deoclécio Alves
author_role author
author2 Xavier, Carlos Henrique
Menezes, Rodrigo Cunha Alvim de
Fontes, Marco Antônio Peliky
Cardoso, Leonardo Máximo
Fernandes, Luciano Gonçalves
Chianca Jr., Deoclécio Alves
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Bezerra, Vanessa Moraes
Xavier, Carlos Henrique
Menezes, Rodrigo Cunha Alvim de
Fontes, Marco Antônio Peliky
Cardoso, Leonardo Máximo
Fernandes, Luciano Gonçalves
Chianca Jr., Deoclécio Alves
Bezerra, Vanessa Moraes
Xavier, Carlos Henrique
Menezes, Rodrigo Cunha Alvim de
Fontes, Marco Antônio Peliky
Cardoso, Leonardo Máximo
Fernandes, Luciano Gonçalves
Chianca Jr., Deoclécio Alves
dc.subject.por.fl_str_mv Protein malnourishment
Bezold–Jarisch reflex
Sino aortic denervation
topic Protein malnourishment
Bezold–Jarisch reflex
Sino aortic denervation
description Texto completo: acesso restrito. p. 48–53
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2014-11-11T18:00:26Z
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dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/16555
dc.identifier.issn.none.fl_str_mv 1566-0702
dc.identifier.number.pt_BR.fl_str_mv v. 162, n. 1-2
identifier_str_mv 1566-0702
v. 162, n. 1-2
url http://repositorio.ufba.br/ri/handle/ri/16555
dc.language.iso.fl_str_mv eng
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