Challenges and Rewards of Research in Marine Natural Products Chemistry in Brazil

Detalhes bibliográficos
Autor(a) principal: Berlinck, Roberto Gomes de Souza
Data de Publicação: 2004
Outros Autores: Hajdu, Eduardo, Rocha, Rosana M. da, Oliveira, Jaine H. H. L. de, Hernández, Isara L. C., Seleghim, Mirna Helena Regali, Granato, Ana Claudia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/7755
Resumo: Texto completo: acesso restrito. p. 510-522
id UFBA-2_eaa13af8752faa9451d2eeddfe93bde9
oai_identifier_str oai:repositorio.ufba.br:ri/7755
network_acronym_str UFBA-2
network_name_str Repositório Institucional da UFBA
repository_id_str 1932
spelling Berlinck, Roberto Gomes de SouzaHajdu, EduardoRocha, Rosana M. daOliveira, Jaine H. H. L. deHernández, Isara L. C.Seleghim, Mirna Helena RegaliGranato, Ana ClaudiaBerlinck, Roberto Gomes de SouzaHajdu, EduardoRocha, Rosana M. daOliveira, Jaine H. H. L. deHernández, Isara L. C.Seleghim, Mirna Helena RegaliGranato, Ana Claudia2013-01-04T14:07:05Z20040163-3864http://www.repositorio.ufba.br/ri/handle/ri/7755v. 67, n. 3Texto completo: acesso restrito. p. 510-522Brazil is blessed with a great biodiversity, which constitutes one of the most important sources of biologically active compounds, even if it has been largely underexplored. As is the case of the Amazon and Atlantic rainforests, the Brazilian marine fauna remains practically unexplored in the search for new biologically active natural products. Considering that marine organisms have been shown to be one of the most promising sources of new bioactive compounds for the treatment of different human diseases, the 8000 km of the Brazilian coastline represents a great potential for finding new pharmacologically active secondary metabolites. This review presents the status of marine natural products chemistry in Brazil, including results reported by different research groups with emphasis on the isolation, structure elucidation, and evaluation of biological activities of natural products isolated from sponges, ascidians, octocorals, and Opistobranch mollusks. A brief overview of the first Brazilian program on the isolation of marine bacteria and fungi, directed toward the production of biologically active compounds, is also discussed. The current multidisciplinary collaborative program under development at the Universidade de São Paulo proposes to establish a new paradigm toward the management of the Brazilian marine biodiversity, integrating research on the species diversity, ecology, taxonomy, and biogeography of marine invertebrates and microorganisms. This program also includes a broad screening program of Brazilian marine bioresources, to search for active compounds that may be of interest for the development of new drug leads.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2013-01-04T14:07:05Z No. of bitstreams: 1 np0304316.pdf: 526392 bytes, checksum: a5b28ded9e612d78437b197b1e6a239d (MD5)Made available in DSpace on 2013-01-04T14:07:05Z (GMT). No. of bitstreams: 1 np0304316.pdf: 526392 bytes, checksum: a5b28ded9e612d78437b197b1e6a239d (MD5) Previous issue date: 2004http://pubs.acs.org/doi/pdfplus/10.1021/np0304316reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAChallenges and Rewards of Research in Marine Natural Products Chemistry in BrazilJournal of Natural Productsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/7755/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52ORIGINALnp0304316.pdfnp0304316.pdfapplication/pdf526392https://repositorio.ufba.br/bitstream/ri/7755/1/np0304316.pdfa5b28ded9e612d78437b197b1e6a239dMD51TEXTnp0304316.pdf.txtnp0304316.pdf.txtExtracted texttext/plain79860https://repositorio.ufba.br/bitstream/ri/7755/3/np0304316.pdf.txtc46b216e75fb314d2ea96bdd4d7574e2MD53ri/77552022-07-05 14:02:49.326oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:02:49Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Challenges and Rewards of Research in Marine Natural Products Chemistry in Brazil
dc.title.alternative.pt_BR.fl_str_mv Journal of Natural Products
title Challenges and Rewards of Research in Marine Natural Products Chemistry in Brazil
spellingShingle Challenges and Rewards of Research in Marine Natural Products Chemistry in Brazil
Berlinck, Roberto Gomes de Souza
title_short Challenges and Rewards of Research in Marine Natural Products Chemistry in Brazil
title_full Challenges and Rewards of Research in Marine Natural Products Chemistry in Brazil
title_fullStr Challenges and Rewards of Research in Marine Natural Products Chemistry in Brazil
title_full_unstemmed Challenges and Rewards of Research in Marine Natural Products Chemistry in Brazil
title_sort Challenges and Rewards of Research in Marine Natural Products Chemistry in Brazil
author Berlinck, Roberto Gomes de Souza
author_facet Berlinck, Roberto Gomes de Souza
Hajdu, Eduardo
Rocha, Rosana M. da
Oliveira, Jaine H. H. L. de
Hernández, Isara L. C.
Seleghim, Mirna Helena Regali
Granato, Ana Claudia
author_role author
author2 Hajdu, Eduardo
Rocha, Rosana M. da
Oliveira, Jaine H. H. L. de
Hernández, Isara L. C.
Seleghim, Mirna Helena Regali
Granato, Ana Claudia
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Berlinck, Roberto Gomes de Souza
Hajdu, Eduardo
Rocha, Rosana M. da
Oliveira, Jaine H. H. L. de
Hernández, Isara L. C.
Seleghim, Mirna Helena Regali
Granato, Ana Claudia
Berlinck, Roberto Gomes de Souza
Hajdu, Eduardo
Rocha, Rosana M. da
Oliveira, Jaine H. H. L. de
Hernández, Isara L. C.
Seleghim, Mirna Helena Regali
Granato, Ana Claudia
description Texto completo: acesso restrito. p. 510-522
publishDate 2004
dc.date.issued.fl_str_mv 2004
dc.date.accessioned.fl_str_mv 2013-01-04T14:07:05Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/7755
dc.identifier.issn.none.fl_str_mv 0163-3864
dc.identifier.number.pt_BR.fl_str_mv v. 67, n. 3
identifier_str_mv 0163-3864
v. 67, n. 3
url http://www.repositorio.ufba.br/ri/handle/ri/7755
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://pubs.acs.org/doi/pdfplus/10.1021/np0304316
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
bitstream.url.fl_str_mv https://repositorio.ufba.br/bitstream/ri/7755/2/license.txt
https://repositorio.ufba.br/bitstream/ri/7755/1/np0304316.pdf
https://repositorio.ufba.br/bitstream/ri/7755/3/np0304316.pdf.txt
bitstream.checksum.fl_str_mv 1b89a9a0548218172d7c829f87a0eab9
a5b28ded9e612d78437b197b1e6a239d
c46b216e75fb314d2ea96bdd4d7574e2
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)
repository.mail.fl_str_mv
_version_ 1808459414855745536

Registros relacionados