Tuberculin reactivity in a population of schoolchildren with high BCG vaccination coverage
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2003 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFBA |
| Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/14267 |
Resumo: | Texto completo: acesso restrito. p. 285-293 |
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Barreto, Mauricio LimaPereira, Susan M.Dourado, Maria Inês CostaBierrenbach, Ana Luiza de SouzaCunha, Sérgio Souza daIchihara, Maria Y.Brito, Silvana Castro deRodrigues, Laura C.Barreto, Mauricio LimaPereira, Susan M.Dourado, Maria Inês CostaBierrenbach, Ana Luiza de SouzaCunha, Sérgio Souza daIchihara, Maria Y.Brito, Silvana Castro deRodrigues, Laura C.2014-01-06T15:03:43Z20031020-4989http://repositorio.ufba.br/ri/handle/ri/14267v. 13, n. 5Texto completo: acesso restrito. p. 285-293OBJECTIVE: To investigate the influence of BCG vaccination or revaccination on tuberculin skin test reactivity, in order to guide the correct interpretation of this test in a setting of high neonatal BCG vaccination coverage and an increasing BCG revaccination coverage at school age. METHODS: We conducted tuberculin skin testing and BCG scar reading in 1148 children aged 7–14 years old in the city of Salvador, Bahia, Brazil. We measured the positive effect of the presence of one or two BCG scars on the proportion of tuberculin skin test results above different cut-off levels (induration sizes of > 5 mm, > 10 mm, and > 15 mm) and also using several ranges of induration size (0, 1–4, 5–9, 10–14, and > 15 mm). We also measured the effects that age, gender, and the school where the child was enrolled had on these proportions. RESULTS: The proportion of tuberculin results > 10 mm was 14.2% (95% confidence interval (CI) = 8.0%–20.3%) for children with no BCG scar, 21.3% (95% CI = 18.5%–24.1%) for children with one BCG scar, and 45.0% (95% CI = 32.0%–58.0%) for children with two BCG scars. There was evidence for an increasing positive effect of the presence of one and two BCG scars on the proportion of results > 5 mm and > 10 mm. Similarly, there was evidence for an increasing positive effect of the presence of one and two scars on the proportion of tuberculin skin test results in the ranges of 5–9 mm and of 10–14 mm. The BCG scar effect on the proportion of results > 5 mm and > 10 mm did not vary with age. There was no evidence for BCG effect on the results > 15 mm. CONCLUSIONS: In Brazilian schoolchildren, BCG-induced tuberculin reactivity is indistinguishable, for results under 15 mm, from reactivity induced by Mycobacterium tuberculosis infection. BCG revaccination at school age increases the degree of BCG-induced tuberculin reactivity found among schoolchildren. This information should be taken into account in tuberculin skin test surveys intended to estimate M. tuberculosis prevalence or to assess transmission patterns as well as in tuberculin skin testing of individuals used as an auxiliary tool in diagnosing tuberculosis. Taking this information into consideration is especially important when there is increasing BCG revaccination coverage.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-01-06T15:03:43Z No. of bitstreams: 1 Maurício L. Barreto.pdf: 161477 bytes, checksum: 4a6b8ca92d47365c60575155cb5639fd (MD5)Made available in DSpace on 2014-01-06T15:03:43Z (GMT). No. of bitstreams: 1 Maurício L. Barreto.pdf: 161477 bytes, checksum: 4a6b8ca92d47365c60575155cb5639fd (MD5) Previous issue date: 2003http://dx.doi.org/10.1590/S1020-49892003000400003reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBATuberculosisBCG vaccineTuberculin testImmunization programsBrazilTuberculin reactivity in a population of schoolchildren with high BCG vaccination coveragePan American Journal of Public Health / Revista Panamericana de Salud Públicainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALMaurício L. Barreto.pdfMaurício L. Barreto.pdfapplication/pdf161477https://repositorio.ufba.br/bitstream/ri/14267/1/Maur%c3%adcio%20L.%20Barreto.pdf4a6b8ca92d47365c60575155cb5639fdMD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/14267/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXTMaurício L. Barreto.pdf.txtMaurício L. Barreto.pdf.txtExtracted texttext/plain45727https://repositorio.ufba.br/bitstream/ri/14267/3/Maur%c3%adcio%20L.%20Barreto.pdf.txt051129c486a55a4d207b35d7fd14b8a7MD53ri/142672022-08-08 13:17:36.25oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-08T16:17:36Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
| dc.title.pt_BR.fl_str_mv |
Tuberculin reactivity in a population of schoolchildren with high BCG vaccination coverage |
| dc.title.alternative.pt_BR.fl_str_mv |
Pan American Journal of Public Health / Revista Panamericana de Salud Pública |
| title |
Tuberculin reactivity in a population of schoolchildren with high BCG vaccination coverage |
| spellingShingle |
Tuberculin reactivity in a population of schoolchildren with high BCG vaccination coverage Barreto, Mauricio Lima Tuberculosis BCG vaccine Tuberculin test Immunization programs Brazil |
| title_short |
Tuberculin reactivity in a population of schoolchildren with high BCG vaccination coverage |
| title_full |
Tuberculin reactivity in a population of schoolchildren with high BCG vaccination coverage |
| title_fullStr |
Tuberculin reactivity in a population of schoolchildren with high BCG vaccination coverage |
| title_full_unstemmed |
Tuberculin reactivity in a population of schoolchildren with high BCG vaccination coverage |
| title_sort |
Tuberculin reactivity in a population of schoolchildren with high BCG vaccination coverage |
| author |
Barreto, Mauricio Lima |
| author_facet |
Barreto, Mauricio Lima Pereira, Susan M. Dourado, Maria Inês Costa Bierrenbach, Ana Luiza de Souza Cunha, Sérgio Souza da Ichihara, Maria Y. Brito, Silvana Castro de Rodrigues, Laura C. |
| author_role |
author |
| author2 |
Pereira, Susan M. Dourado, Maria Inês Costa Bierrenbach, Ana Luiza de Souza Cunha, Sérgio Souza da Ichihara, Maria Y. Brito, Silvana Castro de Rodrigues, Laura C. |
| author2_role |
author author author author author author author |
| dc.contributor.author.fl_str_mv |
Barreto, Mauricio Lima Pereira, Susan M. Dourado, Maria Inês Costa Bierrenbach, Ana Luiza de Souza Cunha, Sérgio Souza da Ichihara, Maria Y. Brito, Silvana Castro de Rodrigues, Laura C. Barreto, Mauricio Lima Pereira, Susan M. Dourado, Maria Inês Costa Bierrenbach, Ana Luiza de Souza Cunha, Sérgio Souza da Ichihara, Maria Y. Brito, Silvana Castro de Rodrigues, Laura C. |
| dc.subject.por.fl_str_mv |
Tuberculosis BCG vaccine Tuberculin test Immunization programs Brazil |
| topic |
Tuberculosis BCG vaccine Tuberculin test Immunization programs Brazil |
| description |
Texto completo: acesso restrito. p. 285-293 |
| publishDate |
2003 |
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2003 |
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2014-01-06T15:03:43Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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http://repositorio.ufba.br/ri/handle/ri/14267 |
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1020-4989 |
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v. 13, n. 5 |
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1020-4989 v. 13, n. 5 |
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http://repositorio.ufba.br/ri/handle/ri/14267 |
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