Effect of essential oils from Mangifera indica L. cultivars on the antifungal susceptibility of Candida spp. strains isolated from dogs

• Autor(a) principal: FONTENELLE,Raquel Oliveira dos Santos
• Data de Publicação: 2017
• Outros Autores: SOBRINHO,Antonio Carlos Nogueira, SOARES,Bruna Vieira, AGUIAR,Francisca Lidiane Linhares de, BRITO,Erika Helena Sales de, CAVALCANTE,Carolina Sidrim de Paula, ROCHA,Marcos Fábio Gadelha, MORAIS,Selene Maia de
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista Brasileira de Saúde e Produção Animal
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-99402017000200337
• topic: mango; yeasts; aromatic oils; caryophyllene oxide; small carnivores

SUMMARY This work reports the chemical study, and anti-Candida spp. activity of leaf essential oil from Mangifera indica cultivars. The essential oils were obtained by hydro-distillation and analyzed by gas chromatography/mass spectroscopy. The anti-Candida spp. activity was evaluated against strains isolated from dogs by the agar-well diffusion method and the minimum inhibitory concentration (MIC) by the broth microdilution method. Tommy Atkins cultivar presented β–selinene (29.49%), caryophyllene oxide (12.40%) and humulene II epoxide (8.66%) as main constituents, while the main constituents of Rosa, Moscatel and Jasmim varieties were caryophyllene oxide (23.62, 48.42 and 30.77%, respectively) and humulene epoxide II (11.56, 23.45, and16.27%, respectively). The means of inhibition zones were 11 ± 0.71, 13.5 ± 3.54, 10.5 ± 0.71 and 13.5 ± 0.71mm to Tommy Atkins, Rosa, Moscatel and Jasmim varieties, respectively. For Tommy Atkins, the MIC ranged from 0.62 to 1.25 mg/mL; for Rosa, ranged from 0.31 to 1.25 mg/mL; for Jasmim ranged from 0.31 to 0.62 mg/mL; while for the Moscatel variety the MIC value was 1.25 mg/mL for all Candida strains. Essential oils of four M. indica cultivars were active in vitro against Candida spp., demonstrating good antifungal activity and can be a useful source of antifungal compounds for veterinary medicine.