Technologic Prospection of Labdane-Type Diterpenes and their Derivatives as Anticancer Agents

Detalhes bibliográficos
Autor(a) principal: Souza-Ferrari, Jailton de
Data de Publicação: 2023
Outros Autores: Oliveira, Wellyson Cavalcante de, Dantas , Bruna Braga
Tipo de documento: Artigo
Idioma: por
Título da fonte: Cadernos de Prospecção (Online)
Texto Completo: https://periodicos.ufba.br/index.php/nit/article/view/51754
Resumo: Labdanes diterpenes are important natural products and express several pharmacological activities of interest, such as anticancer activity. In this sense, this work examined the innovation potential of labdane-type diterpenes as anticancer agents. For this purpose, a patent search was performed in the databases INP1, EPO, WIPO, Derwent Innovations Index, and Lens Patents using “labdane and cancer” as keywords. The results revealed 28 documents considered eligible, distributed among different international patent platforms, with registrations mainly carried out by China (36%), considering the period from 1984 to 2021. These patents are concentrated in A61 (65.06%) and C07 (34.26%) type categories, according to CIP classification. Thus, it can be inferred that there is little innovative activity for use of labdanes as anticancer agents globally, no activity registered in Brazil, and a majority patent classification for biological and chemical applications, which suggests a window of opportunity in this field of innovation.
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spelling Technologic Prospection of Labdane-Type Diterpenes and their Derivatives as Anticancer AgentsProspecção Tecnológica de Diterpenos do Tipo Labdano e seus Derivados como Agentes AnticâncerLabdanosPatentesAnticâncer.LabdanesPatentsAnticancer.Labdanes diterpenes are important natural products and express several pharmacological activities of interest, such as anticancer activity. In this sense, this work examined the innovation potential of labdane-type diterpenes as anticancer agents. For this purpose, a patent search was performed in the databases INP1, EPO, WIPO, Derwent Innovations Index, and Lens Patents using “labdane and cancer” as keywords. The results revealed 28 documents considered eligible, distributed among different international patent platforms, with registrations mainly carried out by China (36%), considering the period from 1984 to 2021. These patents are concentrated in A61 (65.06%) and C07 (34.26%) type categories, according to CIP classification. Thus, it can be inferred that there is little innovative activity for use of labdanes as anticancer agents globally, no activity registered in Brazil, and a majority patent classification for biological and chemical applications, which suggests a window of opportunity in this field of innovation.Diterpenos labdanos são produtos naturais amplamente descritos na literatura científica com potencial farmacológico de interesse biomédico, como atividade anticâncer. Nesse sentido, este trabalho teve como objetivo examinar a atividade inovativa de diterpenos labdanos como agentes anticâncer. Para isso, realizou-se um levantamento dos pedidos de depósito de patentes nas bases de dados INPI, EPO, WIPO, Derwent Innovations Index e Lens Patents empregando as palavras-chave “labdane and cancer”. Os resultados revelaram 28 documentos considerados elegíveis, distribuídos entre distintas plataformas patentárias internacionais com os registros majoritariamente realizados pela China (36%), considerando o período de 1984 a 2021. Essas patentes, segundo a CIP, estão concentradas na categoria A61 (65,06%) e C07 (34,26%). Assim, pode-se inferir que existe pouca atividade inovativa para o uso de labdanos como agentes anticâncer globalmente, nenhuma atividade registrada no Brasil e uma classificação patentária majoritária para aplicações biológicas e químicas, o que sugere uma janela de oportunidade nesse campo de inovação.Universidade Federal da Bahia2023-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.ufba.br/index.php/nit/article/view/5175410.9771/cp.v16i6.51754Cadernos de Prospecção; Vol. 16 No. 6 (2023); 1987-2002Cadernos de Prospecção; v. 16 n. 6 (2023); 1987-20022317-00261983-1358reponame:Cadernos de Prospecção (Online)instname:Universidade Federal da Bahia (UFBA)instacron:UFBAporhttps://periodicos.ufba.br/index.php/nit/article/view/51754/29852Copyright (c) 2023 Cadernos de Prospecçãohttps://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessSouza-Ferrari, Jailton deOliveira, Wellyson Cavalcante de Dantas , Bruna Braga2023-10-01T07:53:56Zoai:ojs.periodicos.ufba.br:article/51754Revistahttps://periodicos.ufba.br/index.php/nitPUBhttps://periodicos.ufba.br/index.php/nit/oaicadernosdeprospeccao@gmail.com || maliceribeiro@yahoo.com.br || cadernosdeprospeccao@gmail.com || saionaraluna@gmail.com2317-00261983-1358opendoar:2023-10-01T07:53:56Cadernos de Prospecção (Online) - Universidade Federal da Bahia (UFBA)false
dc.title.none.fl_str_mv Technologic Prospection of Labdane-Type Diterpenes and their Derivatives as Anticancer Agents
Prospecção Tecnológica de Diterpenos do Tipo Labdano e seus Derivados como Agentes Anticâncer
title Technologic Prospection of Labdane-Type Diterpenes and their Derivatives as Anticancer Agents
spellingShingle Technologic Prospection of Labdane-Type Diterpenes and their Derivatives as Anticancer Agents
Souza-Ferrari, Jailton de
Labdanos
Patentes
Anticâncer.
Labdanes
Patents
Anticancer.
title_short Technologic Prospection of Labdane-Type Diterpenes and their Derivatives as Anticancer Agents
title_full Technologic Prospection of Labdane-Type Diterpenes and their Derivatives as Anticancer Agents
title_fullStr Technologic Prospection of Labdane-Type Diterpenes and their Derivatives as Anticancer Agents
title_full_unstemmed Technologic Prospection of Labdane-Type Diterpenes and their Derivatives as Anticancer Agents
title_sort Technologic Prospection of Labdane-Type Diterpenes and their Derivatives as Anticancer Agents
author Souza-Ferrari, Jailton de
author_facet Souza-Ferrari, Jailton de
Oliveira, Wellyson Cavalcante de
Dantas , Bruna Braga
author_role author
author2 Oliveira, Wellyson Cavalcante de
Dantas , Bruna Braga
author2_role author
author
dc.contributor.author.fl_str_mv Souza-Ferrari, Jailton de
Oliveira, Wellyson Cavalcante de
Dantas , Bruna Braga
dc.subject.por.fl_str_mv Labdanos
Patentes
Anticâncer.
Labdanes
Patents
Anticancer.
topic Labdanos
Patentes
Anticâncer.
Labdanes
Patents
Anticancer.
description Labdanes diterpenes are important natural products and express several pharmacological activities of interest, such as anticancer activity. In this sense, this work examined the innovation potential of labdane-type diterpenes as anticancer agents. For this purpose, a patent search was performed in the databases INP1, EPO, WIPO, Derwent Innovations Index, and Lens Patents using “labdane and cancer” as keywords. The results revealed 28 documents considered eligible, distributed among different international patent platforms, with registrations mainly carried out by China (36%), considering the period from 1984 to 2021. These patents are concentrated in A61 (65.06%) and C07 (34.26%) type categories, according to CIP classification. Thus, it can be inferred that there is little innovative activity for use of labdanes as anticancer agents globally, no activity registered in Brazil, and a majority patent classification for biological and chemical applications, which suggests a window of opportunity in this field of innovation.
publishDate 2023
dc.date.none.fl_str_mv 2023-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.ufba.br/index.php/nit/article/view/51754
10.9771/cp.v16i6.51754
url https://periodicos.ufba.br/index.php/nit/article/view/51754
identifier_str_mv 10.9771/cp.v16i6.51754
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.ufba.br/index.php/nit/article/view/51754/29852
dc.rights.driver.fl_str_mv Copyright (c) 2023 Cadernos de Prospecção
https://creativecommons.org/licenses/by-nc/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2023 Cadernos de Prospecção
https://creativecommons.org/licenses/by-nc/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal da Bahia
publisher.none.fl_str_mv Universidade Federal da Bahia
dc.source.none.fl_str_mv Cadernos de Prospecção; Vol. 16 No. 6 (2023); 1987-2002
Cadernos de Prospecção; v. 16 n. 6 (2023); 1987-2002
2317-0026
1983-1358
reponame:Cadernos de Prospecção (Online)
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Cadernos de Prospecção (Online)
collection Cadernos de Prospecção (Online)
repository.name.fl_str_mv Cadernos de Prospecção (Online) - Universidade Federal da Bahia (UFBA)
repository.mail.fl_str_mv cadernosdeprospeccao@gmail.com || maliceribeiro@yahoo.com.br || cadernosdeprospeccao@gmail.com || saionaraluna@gmail.com
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