Action of two endocrine disrupters on the sexual differenciation of Nile tilapia

Detalhes bibliográficos
Autor(a) principal: Passos Neto,Oscar Pacheco
Data de Publicação: 2019
Outros Autores: Santos,André Bezerra dos, Silva,José Roberto Feitosa, Mota,Suetônio Bastos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista ciência agronômica (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-66902019000300402
Resumo: ABSTRACT Endocrine disruptors are exogenous substances that can impair one or more functions of the endocrine system and cause adverse effects to the health of an intact organism. The main goal of this study was to evaluate the effect of the endocrine disruptors 17β-estradiol (E2) and 17α-ethinyl estradiol (EE2) on the sexual differentiation of Nile tilapia during spawning. Six treatments and one control with three replications, totalizing 21 experimental units, were assessed in a completely randomized design. Hormones were dosed at concentrations of 250, 500, and 1,000 ng L−1 (treatments E2-250, E2-500, E2-1,000, EE2-250, EE2-500, and EE2-1,000). Exposure to hormones occurred during the first 28 days of life. After this period, water was completely renewed and individuals kept in their respective experimental units for another 60 days, totaling 88 days. At the end of this period, animals were euthanized by ice desensitization for gonad extraction, slide preparation, and observation under an optical microscope. At the end of the experiment, the results indicated that the type of hormone and hormone concentration differentially affected the parameters of zootechnical performance. A significant difference (p<0.05) was observed in the condition factor between control and treatments. Intersex individuals were observed in treatments of both hormones, except for the control treatment. In addition, malformations were observed in individuals submitted to treatments, mainly in the head region. Thus, the presence of the chemical compounds 17β-estradiol and 17α-ethinylestradiol severely affected the development and sexual differentiation of Nile tilapia.
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spelling Action of two endocrine disrupters on the sexual differenciation of Nile tilapiaEmerging pollutantsOreochromis niloticus17α-ethinylestradiol17β-estradiolABSTRACT Endocrine disruptors are exogenous substances that can impair one or more functions of the endocrine system and cause adverse effects to the health of an intact organism. The main goal of this study was to evaluate the effect of the endocrine disruptors 17β-estradiol (E2) and 17α-ethinyl estradiol (EE2) on the sexual differentiation of Nile tilapia during spawning. Six treatments and one control with three replications, totalizing 21 experimental units, were assessed in a completely randomized design. Hormones were dosed at concentrations of 250, 500, and 1,000 ng L−1 (treatments E2-250, E2-500, E2-1,000, EE2-250, EE2-500, and EE2-1,000). Exposure to hormones occurred during the first 28 days of life. After this period, water was completely renewed and individuals kept in their respective experimental units for another 60 days, totaling 88 days. At the end of this period, animals were euthanized by ice desensitization for gonad extraction, slide preparation, and observation under an optical microscope. At the end of the experiment, the results indicated that the type of hormone and hormone concentration differentially affected the parameters of zootechnical performance. A significant difference (p<0.05) was observed in the condition factor between control and treatments. Intersex individuals were observed in treatments of both hormones, except for the control treatment. In addition, malformations were observed in individuals submitted to treatments, mainly in the head region. Thus, the presence of the chemical compounds 17β-estradiol and 17α-ethinylestradiol severely affected the development and sexual differentiation of Nile tilapia.Universidade Federal do Ceará2019-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-66902019000300402Revista Ciência Agronômica v.50 n.3 2019reponame:Revista ciência agronômica (Online)instname:Universidade Federal do Ceará (UFC)instacron:UFC10.5935/1806-6690.20190048info:eu-repo/semantics/openAccessPassos Neto,Oscar PachecoSantos,André Bezerra dosSilva,José Roberto FeitosaMota,Suetônio Bastoseng2019-07-02T00:00:00Zoai:scielo:S1806-66902019000300402Revistahttp://www.ccarevista.ufc.br/PUBhttps://old.scielo.br/oai/scielo-oai.php||alekdutra@ufc.br|| ccarev@ufc.br1806-66900045-6888opendoar:2019-07-02T00:00Revista ciência agronômica (Online) - Universidade Federal do Ceará (UFC)false
dc.title.none.fl_str_mv Action of two endocrine disrupters on the sexual differenciation of Nile tilapia
title Action of two endocrine disrupters on the sexual differenciation of Nile tilapia
spellingShingle Action of two endocrine disrupters on the sexual differenciation of Nile tilapia
Passos Neto,Oscar Pacheco
Emerging pollutants
Oreochromis niloticus
17α-ethinylestradiol
17β-estradiol
title_short Action of two endocrine disrupters on the sexual differenciation of Nile tilapia
title_full Action of two endocrine disrupters on the sexual differenciation of Nile tilapia
title_fullStr Action of two endocrine disrupters on the sexual differenciation of Nile tilapia
title_full_unstemmed Action of two endocrine disrupters on the sexual differenciation of Nile tilapia
title_sort Action of two endocrine disrupters on the sexual differenciation of Nile tilapia
author Passos Neto,Oscar Pacheco
author_facet Passos Neto,Oscar Pacheco
Santos,André Bezerra dos
Silva,José Roberto Feitosa
Mota,Suetônio Bastos
author_role author
author2 Santos,André Bezerra dos
Silva,José Roberto Feitosa
Mota,Suetônio Bastos
author2_role author
author
author
dc.contributor.author.fl_str_mv Passos Neto,Oscar Pacheco
Santos,André Bezerra dos
Silva,José Roberto Feitosa
Mota,Suetônio Bastos
dc.subject.por.fl_str_mv Emerging pollutants
Oreochromis niloticus
17α-ethinylestradiol
17β-estradiol
topic Emerging pollutants
Oreochromis niloticus
17α-ethinylestradiol
17β-estradiol
description ABSTRACT Endocrine disruptors are exogenous substances that can impair one or more functions of the endocrine system and cause adverse effects to the health of an intact organism. The main goal of this study was to evaluate the effect of the endocrine disruptors 17β-estradiol (E2) and 17α-ethinyl estradiol (EE2) on the sexual differentiation of Nile tilapia during spawning. Six treatments and one control with three replications, totalizing 21 experimental units, were assessed in a completely randomized design. Hormones were dosed at concentrations of 250, 500, and 1,000 ng L−1 (treatments E2-250, E2-500, E2-1,000, EE2-250, EE2-500, and EE2-1,000). Exposure to hormones occurred during the first 28 days of life. After this period, water was completely renewed and individuals kept in their respective experimental units for another 60 days, totaling 88 days. At the end of this period, animals were euthanized by ice desensitization for gonad extraction, slide preparation, and observation under an optical microscope. At the end of the experiment, the results indicated that the type of hormone and hormone concentration differentially affected the parameters of zootechnical performance. A significant difference (p<0.05) was observed in the condition factor between control and treatments. Intersex individuals were observed in treatments of both hormones, except for the control treatment. In addition, malformations were observed in individuals submitted to treatments, mainly in the head region. Thus, the presence of the chemical compounds 17β-estradiol and 17α-ethinylestradiol severely affected the development and sexual differentiation of Nile tilapia.
publishDate 2019
dc.date.none.fl_str_mv 2019-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-66902019000300402
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-66902019000300402
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/1806-6690.20190048
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Federal do Ceará
publisher.none.fl_str_mv Universidade Federal do Ceará
dc.source.none.fl_str_mv Revista Ciência Agronômica v.50 n.3 2019
reponame:Revista ciência agronômica (Online)
instname:Universidade Federal do Ceará (UFC)
instacron:UFC
instname_str Universidade Federal do Ceará (UFC)
instacron_str UFC
institution UFC
reponame_str Revista ciência agronômica (Online)
collection Revista ciência agronômica (Online)
repository.name.fl_str_mv Revista ciência agronômica (Online) - Universidade Federal do Ceará (UFC)
repository.mail.fl_str_mv ||alekdutra@ufc.br|| ccarev@ufc.br
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