Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da Universidade Federal do Ceará (UFC) |
Texto Completo: | http://www.repositorio.ufc.br/handle/riufc/15268 |
Resumo: | Abstract Renal osteodystrophy (ROD) is the bone pathology that occurs as an uncommon complication related to the several alterations inmineral metabolism present in patientswith chronic kidney disease (CKD). This paper describes two cases of severe ROD affecting the maxilla and mandible and causing facial disfigurement of a young and a middle-aged female patient with CKD. Both patients had a history of secondary hyperparathyroidism, previously treated by surgery. The pathogenesis of the disease, as well as its clinical, imaging, and histopathological features, and management of the patient are discussed. disorder (CKD-MBD), which involves changes in laboratory tests such as serum calcium, organic phosphate, parathyroid hormone (PTH), and concentrations of vitamin D derivatives; changes in bone turnover; and extraskeletal calcifications [3, 4]. Renal osteodystrophy (ROD) has recently been redefined to refer to the bone pathology from this syndrome [5]. Advancements in the knowledge about CKD and its complications, such as secondary hyperparathyroidism (HPT-II) and ROD, resulted in a decreased frequency of significant macroscopic bone al terations in kidney patients. Nonetheless, radiographic changes of the facial skeleton still eventually occur, occasionally involving the jaws, and may represent an early sign of ROD [6–8]. This manuscript reports the details of two unusually severe maxillofacial manifestations of ROD in patients with CKD, emphasizing the laboratorial, clinical, imaging, and histological features as well as patient management. |
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Severe maxillofacial renal osteodystrophy in two patients with chronic kidney diseaseOsteodistrofia RenalInsuficiência Renal CrônicaAbstract Renal osteodystrophy (ROD) is the bone pathology that occurs as an uncommon complication related to the several alterations inmineral metabolism present in patientswith chronic kidney disease (CKD). This paper describes two cases of severe ROD affecting the maxilla and mandible and causing facial disfigurement of a young and a middle-aged female patient with CKD. Both patients had a history of secondary hyperparathyroidism, previously treated by surgery. The pathogenesis of the disease, as well as its clinical, imaging, and histopathological features, and management of the patient are discussed. disorder (CKD-MBD), which involves changes in laboratory tests such as serum calcium, organic phosphate, parathyroid hormone (PTH), and concentrations of vitamin D derivatives; changes in bone turnover; and extraskeletal calcifications [3, 4]. Renal osteodystrophy (ROD) has recently been redefined to refer to the bone pathology from this syndrome [5]. Advancements in the knowledge about CKD and its complications, such as secondary hyperparathyroidism (HPT-II) and ROD, resulted in a decreased frequency of significant macroscopic bone al terations in kidney patients. Nonetheless, radiographic changes of the facial skeleton still eventually occur, occasionally involving the jaws, and may represent an early sign of ROD [6–8]. This manuscript reports the details of two unusually severe maxillofacial manifestations of ROD in patients with CKD, emphasizing the laboratorial, clinical, imaging, and histological features as well as patient management.Oral and Maxillofacial Surgery2016-02-26T11:30:57Z2016-02-26T11:30:57Z2015-09info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfLOPES, M. L. D. S. et al. Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease. Oral and Maxillofacial Surgery, Philadelphia, v. 19, p. 321-327, 2015.1042-3699 Impressohttp://www.repositorio.ufc.br/handle/riufc/15268Lopes, Maria Luiza Diniz de SousaAlbuquerque, Assis Filipe MedeirosGermano, Adriano RochaQueiroz, Lélia Maria GuedesMiguel, Márcia Cristina da CostaSilveira, Éricka Janine Dantas daengreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2019-01-31T12:42:28Zoai:repositorio.ufc.br:riufc/15268Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2024-09-11T18:30:32.891303Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false |
dc.title.none.fl_str_mv |
Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease |
title |
Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease |
spellingShingle |
Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease Lopes, Maria Luiza Diniz de Sousa Osteodistrofia Renal Insuficiência Renal Crônica |
title_short |
Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease |
title_full |
Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease |
title_fullStr |
Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease |
title_full_unstemmed |
Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease |
title_sort |
Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease |
author |
Lopes, Maria Luiza Diniz de Sousa |
author_facet |
Lopes, Maria Luiza Diniz de Sousa Albuquerque, Assis Filipe Medeiros Germano, Adriano Rocha Queiroz, Lélia Maria Guedes Miguel, Márcia Cristina da Costa Silveira, Éricka Janine Dantas da |
author_role |
author |
author2 |
Albuquerque, Assis Filipe Medeiros Germano, Adriano Rocha Queiroz, Lélia Maria Guedes Miguel, Márcia Cristina da Costa Silveira, Éricka Janine Dantas da |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Lopes, Maria Luiza Diniz de Sousa Albuquerque, Assis Filipe Medeiros Germano, Adriano Rocha Queiroz, Lélia Maria Guedes Miguel, Márcia Cristina da Costa Silveira, Éricka Janine Dantas da |
dc.subject.por.fl_str_mv |
Osteodistrofia Renal Insuficiência Renal Crônica |
topic |
Osteodistrofia Renal Insuficiência Renal Crônica |
description |
Abstract Renal osteodystrophy (ROD) is the bone pathology that occurs as an uncommon complication related to the several alterations inmineral metabolism present in patientswith chronic kidney disease (CKD). This paper describes two cases of severe ROD affecting the maxilla and mandible and causing facial disfigurement of a young and a middle-aged female patient with CKD. Both patients had a history of secondary hyperparathyroidism, previously treated by surgery. The pathogenesis of the disease, as well as its clinical, imaging, and histopathological features, and management of the patient are discussed. disorder (CKD-MBD), which involves changes in laboratory tests such as serum calcium, organic phosphate, parathyroid hormone (PTH), and concentrations of vitamin D derivatives; changes in bone turnover; and extraskeletal calcifications [3, 4]. Renal osteodystrophy (ROD) has recently been redefined to refer to the bone pathology from this syndrome [5]. Advancements in the knowledge about CKD and its complications, such as secondary hyperparathyroidism (HPT-II) and ROD, resulted in a decreased frequency of significant macroscopic bone al terations in kidney patients. Nonetheless, radiographic changes of the facial skeleton still eventually occur, occasionally involving the jaws, and may represent an early sign of ROD [6–8]. This manuscript reports the details of two unusually severe maxillofacial manifestations of ROD in patients with CKD, emphasizing the laboratorial, clinical, imaging, and histological features as well as patient management. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-09 2016-02-26T11:30:57Z 2016-02-26T11:30:57Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
LOPES, M. L. D. S. et al. Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease. Oral and Maxillofacial Surgery, Philadelphia, v. 19, p. 321-327, 2015. 1042-3699 Impresso http://www.repositorio.ufc.br/handle/riufc/15268 |
identifier_str_mv |
LOPES, M. L. D. S. et al. Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease. Oral and Maxillofacial Surgery, Philadelphia, v. 19, p. 321-327, 2015. 1042-3699 Impresso |
url |
http://www.repositorio.ufc.br/handle/riufc/15268 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Oral and Maxillofacial Surgery |
publisher.none.fl_str_mv |
Oral and Maxillofacial Surgery |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da Universidade Federal do Ceará (UFC) instname:Universidade Federal do Ceará (UFC) instacron:UFC |
instname_str |
Universidade Federal do Ceará (UFC) |
instacron_str |
UFC |
institution |
UFC |
reponame_str |
Repositório Institucional da Universidade Federal do Ceará (UFC) |
collection |
Repositório Institucional da Universidade Federal do Ceará (UFC) |
repository.name.fl_str_mv |
Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC) |
repository.mail.fl_str_mv |
bu@ufc.br || repositorio@ufc.br |
_version_ |
1813028833875460096 |