Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease

Detalhes bibliográficos
Autor(a) principal: Lopes, Maria Luiza Diniz de Sousa
Data de Publicação: 2015
Outros Autores: Albuquerque, Assis Filipe Medeiros, Germano, Adriano Rocha, Queiroz, Lélia Maria Guedes, Miguel, Márcia Cristina da Costa, Silveira, Éricka Janine Dantas da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
Texto Completo: http://www.repositorio.ufc.br/handle/riufc/15268
Resumo: Abstract Renal osteodystrophy (ROD) is the bone pathology that occurs as an uncommon complication related to the several alterations inmineral metabolism present in patientswith chronic kidney disease (CKD). This paper describes two cases of severe ROD affecting the maxilla and mandible and causing facial disfigurement of a young and a middle-aged female patient with CKD. Both patients had a history of secondary hyperparathyroidism, previously treated by surgery. The pathogenesis of the disease, as well as its clinical, imaging, and histopathological features, and management of the patient are discussed. disorder (CKD-MBD), which involves changes in laboratory tests such as serum calcium, organic phosphate, parathyroid hormone (PTH), and concentrations of vitamin D derivatives; changes in bone turnover; and extraskeletal calcifications [3, 4]. Renal osteodystrophy (ROD) has recently been redefined to refer to the bone pathology from this syndrome [5]. Advancements in the knowledge about CKD and its complications, such as secondary hyperparathyroidism (HPT-II) and ROD, resulted in a decreased frequency of significant macroscopic bone al terations in kidney patients. Nonetheless, radiographic changes of the facial skeleton still eventually occur, occasionally involving the jaws, and may represent an early sign of ROD [6–8]. This manuscript reports the details of two unusually severe maxillofacial manifestations of ROD in patients with CKD, emphasizing the laboratorial, clinical, imaging, and histological features as well as patient management.
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spelling Severe maxillofacial renal osteodystrophy in two patients with chronic kidney diseaseOsteodistrofia RenalInsuficiência Renal CrônicaAbstract Renal osteodystrophy (ROD) is the bone pathology that occurs as an uncommon complication related to the several alterations inmineral metabolism present in patientswith chronic kidney disease (CKD). This paper describes two cases of severe ROD affecting the maxilla and mandible and causing facial disfigurement of a young and a middle-aged female patient with CKD. Both patients had a history of secondary hyperparathyroidism, previously treated by surgery. The pathogenesis of the disease, as well as its clinical, imaging, and histopathological features, and management of the patient are discussed. disorder (CKD-MBD), which involves changes in laboratory tests such as serum calcium, organic phosphate, parathyroid hormone (PTH), and concentrations of vitamin D derivatives; changes in bone turnover; and extraskeletal calcifications [3, 4]. Renal osteodystrophy (ROD) has recently been redefined to refer to the bone pathology from this syndrome [5]. Advancements in the knowledge about CKD and its complications, such as secondary hyperparathyroidism (HPT-II) and ROD, resulted in a decreased frequency of significant macroscopic bone al terations in kidney patients. Nonetheless, radiographic changes of the facial skeleton still eventually occur, occasionally involving the jaws, and may represent an early sign of ROD [6–8]. This manuscript reports the details of two unusually severe maxillofacial manifestations of ROD in patients with CKD, emphasizing the laboratorial, clinical, imaging, and histological features as well as patient management.Oral and Maxillofacial Surgery2016-02-26T11:30:57Z2016-02-26T11:30:57Z2015-09info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfLOPES, M. L. D. S. et al. Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease. Oral and Maxillofacial Surgery, Philadelphia, v. 19, p. 321-327, 2015.1042-3699 Impressohttp://www.repositorio.ufc.br/handle/riufc/15268Lopes, Maria Luiza Diniz de SousaAlbuquerque, Assis Filipe MedeirosGermano, Adriano RochaQueiroz, Lélia Maria GuedesMiguel, Márcia Cristina da CostaSilveira, Éricka Janine Dantas daengreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2019-01-31T12:42:28Zoai:repositorio.ufc.br:riufc/15268Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2024-09-11T18:30:32.891303Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false
dc.title.none.fl_str_mv Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease
title Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease
spellingShingle Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease
Lopes, Maria Luiza Diniz de Sousa
Osteodistrofia Renal
Insuficiência Renal Crônica
title_short Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease
title_full Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease
title_fullStr Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease
title_full_unstemmed Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease
title_sort Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease
author Lopes, Maria Luiza Diniz de Sousa
author_facet Lopes, Maria Luiza Diniz de Sousa
Albuquerque, Assis Filipe Medeiros
Germano, Adriano Rocha
Queiroz, Lélia Maria Guedes
Miguel, Márcia Cristina da Costa
Silveira, Éricka Janine Dantas da
author_role author
author2 Albuquerque, Assis Filipe Medeiros
Germano, Adriano Rocha
Queiroz, Lélia Maria Guedes
Miguel, Márcia Cristina da Costa
Silveira, Éricka Janine Dantas da
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Lopes, Maria Luiza Diniz de Sousa
Albuquerque, Assis Filipe Medeiros
Germano, Adriano Rocha
Queiroz, Lélia Maria Guedes
Miguel, Márcia Cristina da Costa
Silveira, Éricka Janine Dantas da
dc.subject.por.fl_str_mv Osteodistrofia Renal
Insuficiência Renal Crônica
topic Osteodistrofia Renal
Insuficiência Renal Crônica
description Abstract Renal osteodystrophy (ROD) is the bone pathology that occurs as an uncommon complication related to the several alterations inmineral metabolism present in patientswith chronic kidney disease (CKD). This paper describes two cases of severe ROD affecting the maxilla and mandible and causing facial disfigurement of a young and a middle-aged female patient with CKD. Both patients had a history of secondary hyperparathyroidism, previously treated by surgery. The pathogenesis of the disease, as well as its clinical, imaging, and histopathological features, and management of the patient are discussed. disorder (CKD-MBD), which involves changes in laboratory tests such as serum calcium, organic phosphate, parathyroid hormone (PTH), and concentrations of vitamin D derivatives; changes in bone turnover; and extraskeletal calcifications [3, 4]. Renal osteodystrophy (ROD) has recently been redefined to refer to the bone pathology from this syndrome [5]. Advancements in the knowledge about CKD and its complications, such as secondary hyperparathyroidism (HPT-II) and ROD, resulted in a decreased frequency of significant macroscopic bone al terations in kidney patients. Nonetheless, radiographic changes of the facial skeleton still eventually occur, occasionally involving the jaws, and may represent an early sign of ROD [6–8]. This manuscript reports the details of two unusually severe maxillofacial manifestations of ROD in patients with CKD, emphasizing the laboratorial, clinical, imaging, and histological features as well as patient management.
publishDate 2015
dc.date.none.fl_str_mv 2015-09
2016-02-26T11:30:57Z
2016-02-26T11:30:57Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv LOPES, M. L. D. S. et al. Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease. Oral and Maxillofacial Surgery, Philadelphia, v. 19, p. 321-327, 2015.
1042-3699 Impresso
http://www.repositorio.ufc.br/handle/riufc/15268
identifier_str_mv LOPES, M. L. D. S. et al. Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease. Oral and Maxillofacial Surgery, Philadelphia, v. 19, p. 321-327, 2015.
1042-3699 Impresso
url http://www.repositorio.ufc.br/handle/riufc/15268
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Oral and Maxillofacial Surgery
publisher.none.fl_str_mv Oral and Maxillofacial Surgery
dc.source.none.fl_str_mv reponame:Repositório Institucional da Universidade Federal do Ceará (UFC)
instname:Universidade Federal do Ceará (UFC)
instacron:UFC
instname_str Universidade Federal do Ceará (UFC)
instacron_str UFC
institution UFC
reponame_str Repositório Institucional da Universidade Federal do Ceará (UFC)
collection Repositório Institucional da Universidade Federal do Ceará (UFC)
repository.name.fl_str_mv Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)
repository.mail.fl_str_mv bu@ufc.br || repositorio@ufc.br
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