Avaliação dos testes de diagnóstico das formas clínicas de leishmaniose tegumentar realizados no Setor de Parasitologia/DPML/FAMED no período de 2015 a 2020

• Autor(a) principal: Ferreira, Maria Beatriz dos Santos
• Data de Publicação: 2021
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
• dARK ID: ark:/83112/001300000spjr
• Texto Completo: http://www.repositorio.ufc.br/handle/riufc/60730
• topic: Técnicas de diagnóstico; Leishmaniose Tegumentar; Intradermorreação de Montenegro

Tegumentary leishmaniasis (LT) is an infection-parasitic disease of high incidence in tropical and intertropical areas, which mainly affects socioeconomically vulnerable populations, being caused by parasites of the genus Leishmania. LT has a wide spectrum of clinical manifestations, such as localized cutaneous leishmaniasis (LCL), disseminated cutaneous leishmaniasis (LD), diffuse cutaneous leishmaniasis (LCD), mucocutaneous leishmaniasis (LM). The diagnosis of LT is obtained through parasitological tools, such as direct examinations and parasite culture; immunological tools, through serology and the Montenegro Intradermal Reaction (IDRM); and histological ways, such as the staining of the material by HE and immunohistochemistry. The aim of this study was to evaluate the parasitological test and IDRM for the diagnosis of the different clinical forms of LT in patients attend at the Parasitology Laboratory/DPML/UFC, from 2015 to 2020. Thus, information was collected from patients obtained from the parasitological test registry of the Parasitology Sector regarding age, gender, symptomatology, ulcer site, requested examinations and results. The sample consisted of 177 individuals, 70 (39,5%) women and 107 (60,5%) men, of which 101 (57,1%) underwent biopsy test, 134 (57,7%) culture test and 26 (14,7%) IDRM test. Patients came from reference hospitals for infectious diseases of Fortaleza, Ceará. Of those tested by biopsy 10% were positive, 4% of those tested by culture were positive and the IDRM was positive in 81% of the individuals tested. Regarding the gender of individuals, most of those tested were men and in all tests the highest percentage of positivity belongs to this sex. Therefore, this study confirms the need for the association of more than one laboratory test for a more accurate diagnosis of LT, especially for mucocutaneous leishmaniasis, a more severe form and more difficult to diagnose.