Maternal and infant death after probable vertical transmission of chikungunya virus in Brazil : case report

• Autor(a) principal: Oliveira, Rhaquel de Morais Alves Barbosa
• Data de Publicação: 2018
• Outros Autores: Barreto, Francisca Kalline de Almeida, Maia, Ana Maria Peixoto Cabral, Gomes, Ileana Pitombeira, Simião, Adriana Rocha, Barbosa, Rebeca Bandeira, Rodrigues, Adilina Soares Romeiro, Lopes, Kilma Wanderley, Araújo, Fernanda Montenegro de Carvalho, Vale, Regina Lúcia Sousa do, Cavalcante, John Washington, Cavalcanti, Luciano Pamplona de Góes
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
• Texto Completo: http://www.repositorio.ufc.br/handle/riufc/45690
• topic: Morte Materna; Maternal Death; Vírus Chikungunya

Background Chikungunya virus infection in neonates is relatively rare and can lead to death. Case presentation We report the occurrence of the first death of a mother and child after probable vertical transmission of chikungunya virus in Brazil. A 28-year-old pregnant woman with hypertension presented with symptoms compatible with an arboviral disease at 34 weeks’ gestation. She developed preeclampsia with severe respiratory failure which resulted in the emergency cesarean section, and the patient died 12 days after the onset of symptoms. The pre-term newborn weighed 2535 g, with an Apgar score of 4/8. He was referred to the neonatal ICU with neutrophilia and thrombocytopenia, several seizure episodes, and hemorrhagic disorders, which resulted in death. Chikungunya IgM antibody was detected in the cerebrospinal fluid. Conclusions We present the first documented maternal and neonatal death in Brazil after probable chikungunya infection during pregnancy.