Identification of long non-coding RNAs in two anthozoan species and their possible implications for coral bleaching

Detalhes bibliográficos
Autor(a) principal: Huang, Chen
Data de Publicação: 2017
Outros Autores: Morlighem, Jean-Étienne R. L., Cai, Jing, Liao, Qiwen, Perez, Carlos Daniel, Gomes, Paula Braga, Guo, Min, Rádis-Baptista, Gandhi, Lee, Simon Ming-Yuen
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
Texto Completo: http://www.repositorio.ufc.br/handle/riufc/26506
Resumo: Long non-coding RNAs (lncRNAs) have been shown to play regulatory roles in a diverse range of biological processes and are associated with the outcomes of various diseases. The majority of studies about lncRNAs focus on model organisms, with lessened investigation in non-model organisms to date. Herein, we have undertaken an investigation on lncRNA in two zoanthids (cnidarian): Protolpalythoa varibilis and Palythoa caribaeorum. A total of 11,206 and 13,240 lncRNAs were detected in P. variabilis and P. caribaeorum transcriptome, respectively. Comparison using NONCODE database indicated that the majority of these lncRNAs is taxonomically species-restricted with no identifiable orthologs. Even so, we found cases in which short regions of P. caribaeorum’s lncRNAs were similar to vertebrate species’ lncRNAs, and could be associated with lncRNA conserved regulatory functions. Consequently, some high-confidence lncRNA-mRNA interactions were predicted based on such conserved regions, therefore revealing possible involvement of lncRNAs in posttranscriptional processing and regulation in anthozoans. Moreover, investigation of differentially expressed lncRNAs, in healthy colonies and colonial individuals undergoing natural bleaching, indicated that some up-regulated lncRNAs in P. caribaeorum could posttranscriptionally regulate the mRNAs encoding proteins of Ras-mediated signal transduction pathway and components of innate immune-system, which could contribute to the molecular response of coral bleaching.
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spelling Identification of long non-coding RNAs in two anthozoan species and their possible implications for coral bleachingAntozoáriosAnthozoaLong non-coding RNAs (lncRNAs) have been shown to play regulatory roles in a diverse range of biological processes and are associated with the outcomes of various diseases. The majority of studies about lncRNAs focus on model organisms, with lessened investigation in non-model organisms to date. Herein, we have undertaken an investigation on lncRNA in two zoanthids (cnidarian): Protolpalythoa varibilis and Palythoa caribaeorum. A total of 11,206 and 13,240 lncRNAs were detected in P. variabilis and P. caribaeorum transcriptome, respectively. Comparison using NONCODE database indicated that the majority of these lncRNAs is taxonomically species-restricted with no identifiable orthologs. Even so, we found cases in which short regions of P. caribaeorum’s lncRNAs were similar to vertebrate species’ lncRNAs, and could be associated with lncRNA conserved regulatory functions. Consequently, some high-confidence lncRNA-mRNA interactions were predicted based on such conserved regions, therefore revealing possible involvement of lncRNAs in posttranscriptional processing and regulation in anthozoans. Moreover, investigation of differentially expressed lncRNAs, in healthy colonies and colonial individuals undergoing natural bleaching, indicated that some up-regulated lncRNAs in P. caribaeorum could posttranscriptionally regulate the mRNAs encoding proteins of Ras-mediated signal transduction pathway and components of innate immune-system, which could contribute to the molecular response of coral bleaching.Scientific Reports2017-10-09T18:38:06Z2017-10-09T18:38:06Z2017-07info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfHUANG, C. et al. Identification of long non-coding RNAs in two anthozoan species and their possible implications for coral bleaching. Scientific Reports, v. 7, p. 1-18, jul. 2017.2045-2322http://www.repositorio.ufc.br/handle/riufc/26506Huang, ChenMorlighem, Jean-Étienne R. L.Cai, JingLiao, QiwenPerez, Carlos DanielGomes, Paula BragaGuo, MinRádis-Baptista, GandhiLee, Simon Ming-Yuenengreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2022-05-31T13:59:21Zoai:repositorio.ufc.br:riufc/26506Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2024-09-11T18:30:03.081782Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false
dc.title.none.fl_str_mv Identification of long non-coding RNAs in two anthozoan species and their possible implications for coral bleaching
title Identification of long non-coding RNAs in two anthozoan species and their possible implications for coral bleaching
spellingShingle Identification of long non-coding RNAs in two anthozoan species and their possible implications for coral bleaching
Huang, Chen
Antozoários
Anthozoa
title_short Identification of long non-coding RNAs in two anthozoan species and their possible implications for coral bleaching
title_full Identification of long non-coding RNAs in two anthozoan species and their possible implications for coral bleaching
title_fullStr Identification of long non-coding RNAs in two anthozoan species and their possible implications for coral bleaching
title_full_unstemmed Identification of long non-coding RNAs in two anthozoan species and their possible implications for coral bleaching
title_sort Identification of long non-coding RNAs in two anthozoan species and their possible implications for coral bleaching
author Huang, Chen
author_facet Huang, Chen
Morlighem, Jean-Étienne R. L.
Cai, Jing
Liao, Qiwen
Perez, Carlos Daniel
Gomes, Paula Braga
Guo, Min
Rádis-Baptista, Gandhi
Lee, Simon Ming-Yuen
author_role author
author2 Morlighem, Jean-Étienne R. L.
Cai, Jing
Liao, Qiwen
Perez, Carlos Daniel
Gomes, Paula Braga
Guo, Min
Rádis-Baptista, Gandhi
Lee, Simon Ming-Yuen
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Huang, Chen
Morlighem, Jean-Étienne R. L.
Cai, Jing
Liao, Qiwen
Perez, Carlos Daniel
Gomes, Paula Braga
Guo, Min
Rádis-Baptista, Gandhi
Lee, Simon Ming-Yuen
dc.subject.por.fl_str_mv Antozoários
Anthozoa
topic Antozoários
Anthozoa
description Long non-coding RNAs (lncRNAs) have been shown to play regulatory roles in a diverse range of biological processes and are associated with the outcomes of various diseases. The majority of studies about lncRNAs focus on model organisms, with lessened investigation in non-model organisms to date. Herein, we have undertaken an investigation on lncRNA in two zoanthids (cnidarian): Protolpalythoa varibilis and Palythoa caribaeorum. A total of 11,206 and 13,240 lncRNAs were detected in P. variabilis and P. caribaeorum transcriptome, respectively. Comparison using NONCODE database indicated that the majority of these lncRNAs is taxonomically species-restricted with no identifiable orthologs. Even so, we found cases in which short regions of P. caribaeorum’s lncRNAs were similar to vertebrate species’ lncRNAs, and could be associated with lncRNA conserved regulatory functions. Consequently, some high-confidence lncRNA-mRNA interactions were predicted based on such conserved regions, therefore revealing possible involvement of lncRNAs in posttranscriptional processing and regulation in anthozoans. Moreover, investigation of differentially expressed lncRNAs, in healthy colonies and colonial individuals undergoing natural bleaching, indicated that some up-regulated lncRNAs in P. caribaeorum could posttranscriptionally regulate the mRNAs encoding proteins of Ras-mediated signal transduction pathway and components of innate immune-system, which could contribute to the molecular response of coral bleaching.
publishDate 2017
dc.date.none.fl_str_mv 2017-10-09T18:38:06Z
2017-10-09T18:38:06Z
2017-07
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv HUANG, C. et al. Identification of long non-coding RNAs in two anthozoan species and their possible implications for coral bleaching. Scientific Reports, v. 7, p. 1-18, jul. 2017.
2045-2322
http://www.repositorio.ufc.br/handle/riufc/26506
identifier_str_mv HUANG, C. et al. Identification of long non-coding RNAs in two anthozoan species and their possible implications for coral bleaching. Scientific Reports, v. 7, p. 1-18, jul. 2017.
2045-2322
url http://www.repositorio.ufc.br/handle/riufc/26506
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Scientific Reports
publisher.none.fl_str_mv Scientific Reports
dc.source.none.fl_str_mv reponame:Repositório Institucional da Universidade Federal do Ceará (UFC)
instname:Universidade Federal do Ceará (UFC)
instacron:UFC
instname_str Universidade Federal do Ceará (UFC)
instacron_str UFC
institution UFC
reponame_str Repositório Institucional da Universidade Federal do Ceará (UFC)
collection Repositório Institucional da Universidade Federal do Ceará (UFC)
repository.name.fl_str_mv Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)
repository.mail.fl_str_mv bu@ufc.br || repositorio@ufc.br
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