Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries

Detalhes bibliográficos
Autor(a) principal: Koyanagi, Ai
Data de Publicação: 2018
Outros Autores: Lara, Elvira, Stubbs, Brendon, Carvalho, Andre F., Oh, Hans, Stickley, Andrew, Veronese, Nicola, Vancampfort, Davy
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
Texto Completo: http://www.repositorio.ufc.br/handle/riufc/32333
Resumo: OBJECTIVES: To assess the association between chronic physical conditions and multimorbidity and mild cognitive impairment (MCI) in low- and middle-income countries (LMICs). DESIGN: Nationally representative, cross-sectional, community- based study. SETTING: Six countries that participated in the World Health Organization Study on Global Ageing and Adult Health. PARTICIPANTS: Individuals aged 50 and older (N532,715; mean age 62.1615.6; 51.7% female). MEASUREMENTS: The definition of MCI was based on the recommendations of the National Institute on Ageing and Alzheimer’s Association. Ten chronic conditions were assessed (angina pectoris, arthritis, asthma, cataract, chronic lung disease, diabetes mellitus, edentulism, hearing problems, hypertension, stroke). Multivariable logistic regression analysis was conducted to assess the association between chronic physical conditions, multimorbidity ( 2 chronic conditions), and MCI. RESULTS: The prevalence of multimorbidity was 49.8% (95% confidence interval (CI)548.1–51.5%) and of MCI was 15.3% (95% CI514.4–16.3%). After adjustment for potential confounders, edentulism (odds ratio (OR)51.24), arthritis (OR51.24), chronic lung disease (OR51.29), cataract (OR51.33), stroke (OR51.94), hearing problems (OR52.27), and multimorbidity (OR51.40) were significantly associated with MCI. There was a gradual increase in the likelihood of MCI (1 condition: OR51.21, 95% CI51.03–1.42; 4 conditions: OR52.07, 95% CI51.70–2.52). CONCLUSION: These results highlight the need to investigate the underlying mechanisms linking chronic conditions and MCI and whether prevention or treatment of chronic conditions or multimorbidity can reduce the onset of cognitive decline and subsequent dementia, especially in LMICs.
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spelling Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countriesDisfunção CognitivaCognitive DysfunctionOBJECTIVES: To assess the association between chronic physical conditions and multimorbidity and mild cognitive impairment (MCI) in low- and middle-income countries (LMICs). DESIGN: Nationally representative, cross-sectional, community- based study. SETTING: Six countries that participated in the World Health Organization Study on Global Ageing and Adult Health. PARTICIPANTS: Individuals aged 50 and older (N532,715; mean age 62.1615.6; 51.7% female). MEASUREMENTS: The definition of MCI was based on the recommendations of the National Institute on Ageing and Alzheimer’s Association. Ten chronic conditions were assessed (angina pectoris, arthritis, asthma, cataract, chronic lung disease, diabetes mellitus, edentulism, hearing problems, hypertension, stroke). Multivariable logistic regression analysis was conducted to assess the association between chronic physical conditions, multimorbidity ( 2 chronic conditions), and MCI. RESULTS: The prevalence of multimorbidity was 49.8% (95% confidence interval (CI)548.1–51.5%) and of MCI was 15.3% (95% CI514.4–16.3%). After adjustment for potential confounders, edentulism (odds ratio (OR)51.24), arthritis (OR51.24), chronic lung disease (OR51.29), cataract (OR51.33), stroke (OR51.94), hearing problems (OR52.27), and multimorbidity (OR51.40) were significantly associated with MCI. There was a gradual increase in the likelihood of MCI (1 condition: OR51.21, 95% CI51.03–1.42; 4 conditions: OR52.07, 95% CI51.70–2.52). CONCLUSION: These results highlight the need to investigate the underlying mechanisms linking chronic conditions and MCI and whether prevention or treatment of chronic conditions or multimorbidity can reduce the onset of cognitive decline and subsequent dementia, especially in LMICs.Journal of the American Geriatrics Society2018-05-28T14:17:01Z2018-05-28T14:17:01Z2018-04info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfKOYANAGI, A. et al. Chronic physical conditions, multimorbidity, and mild cognitive impairment in low‐and middle‐income countries. J Am Geriatr Soc., New York, v. 66, n. 4, p. 721-727, apr. 2018.0002-8614http://www.repositorio.ufc.br/handle/riufc/32333Koyanagi, AiLara, ElviraStubbs, BrendonCarvalho, Andre F.Oh, HansStickley, AndrewVeronese, NicolaVancampfort, Davyengreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2021-03-29T19:35:09Zoai:repositorio.ufc.br:riufc/32333Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2024-09-11T18:29:36.794184Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false
dc.title.none.fl_str_mv Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries
title Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries
spellingShingle Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries
Koyanagi, Ai
Disfunção Cognitiva
Cognitive Dysfunction
title_short Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries
title_full Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries
title_fullStr Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries
title_full_unstemmed Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries
title_sort Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries
author Koyanagi, Ai
author_facet Koyanagi, Ai
Lara, Elvira
Stubbs, Brendon
Carvalho, Andre F.
Oh, Hans
Stickley, Andrew
Veronese, Nicola
Vancampfort, Davy
author_role author
author2 Lara, Elvira
Stubbs, Brendon
Carvalho, Andre F.
Oh, Hans
Stickley, Andrew
Veronese, Nicola
Vancampfort, Davy
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Koyanagi, Ai
Lara, Elvira
Stubbs, Brendon
Carvalho, Andre F.
Oh, Hans
Stickley, Andrew
Veronese, Nicola
Vancampfort, Davy
dc.subject.por.fl_str_mv Disfunção Cognitiva
Cognitive Dysfunction
topic Disfunção Cognitiva
Cognitive Dysfunction
description OBJECTIVES: To assess the association between chronic physical conditions and multimorbidity and mild cognitive impairment (MCI) in low- and middle-income countries (LMICs). DESIGN: Nationally representative, cross-sectional, community- based study. SETTING: Six countries that participated in the World Health Organization Study on Global Ageing and Adult Health. PARTICIPANTS: Individuals aged 50 and older (N532,715; mean age 62.1615.6; 51.7% female). MEASUREMENTS: The definition of MCI was based on the recommendations of the National Institute on Ageing and Alzheimer’s Association. Ten chronic conditions were assessed (angina pectoris, arthritis, asthma, cataract, chronic lung disease, diabetes mellitus, edentulism, hearing problems, hypertension, stroke). Multivariable logistic regression analysis was conducted to assess the association between chronic physical conditions, multimorbidity ( 2 chronic conditions), and MCI. RESULTS: The prevalence of multimorbidity was 49.8% (95% confidence interval (CI)548.1–51.5%) and of MCI was 15.3% (95% CI514.4–16.3%). After adjustment for potential confounders, edentulism (odds ratio (OR)51.24), arthritis (OR51.24), chronic lung disease (OR51.29), cataract (OR51.33), stroke (OR51.94), hearing problems (OR52.27), and multimorbidity (OR51.40) were significantly associated with MCI. There was a gradual increase in the likelihood of MCI (1 condition: OR51.21, 95% CI51.03–1.42; 4 conditions: OR52.07, 95% CI51.70–2.52). CONCLUSION: These results highlight the need to investigate the underlying mechanisms linking chronic conditions and MCI and whether prevention or treatment of chronic conditions or multimorbidity can reduce the onset of cognitive decline and subsequent dementia, especially in LMICs.
publishDate 2018
dc.date.none.fl_str_mv 2018-05-28T14:17:01Z
2018-05-28T14:17:01Z
2018-04
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv KOYANAGI, A. et al. Chronic physical conditions, multimorbidity, and mild cognitive impairment in low‐and middle‐income countries. J Am Geriatr Soc., New York, v. 66, n. 4, p. 721-727, apr. 2018.
0002-8614
http://www.repositorio.ufc.br/handle/riufc/32333
identifier_str_mv KOYANAGI, A. et al. Chronic physical conditions, multimorbidity, and mild cognitive impairment in low‐and middle‐income countries. J Am Geriatr Soc., New York, v. 66, n. 4, p. 721-727, apr. 2018.
0002-8614
url http://www.repositorio.ufc.br/handle/riufc/32333
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Journal of the American Geriatrics Society
publisher.none.fl_str_mv Journal of the American Geriatrics Society
dc.source.none.fl_str_mv reponame:Repositório Institucional da Universidade Federal do Ceará (UFC)
instname:Universidade Federal do Ceará (UFC)
instacron:UFC
instname_str Universidade Federal do Ceará (UFC)
instacron_str UFC
institution UFC
reponame_str Repositório Institucional da Universidade Federal do Ceará (UFC)
collection Repositório Institucional da Universidade Federal do Ceará (UFC)
repository.name.fl_str_mv Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)
repository.mail.fl_str_mv bu@ufc.br || repositorio@ufc.br
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