Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da Universidade Federal do Ceará (UFC) |
Texto Completo: | http://www.repositorio.ufc.br/handle/riufc/32333 |
Resumo: | OBJECTIVES: To assess the association between chronic physical conditions and multimorbidity and mild cognitive impairment (MCI) in low- and middle-income countries (LMICs). DESIGN: Nationally representative, cross-sectional, community- based study. SETTING: Six countries that participated in the World Health Organization Study on Global Ageing and Adult Health. PARTICIPANTS: Individuals aged 50 and older (N532,715; mean age 62.1615.6; 51.7% female). MEASUREMENTS: The definition of MCI was based on the recommendations of the National Institute on Ageing and Alzheimer’s Association. Ten chronic conditions were assessed (angina pectoris, arthritis, asthma, cataract, chronic lung disease, diabetes mellitus, edentulism, hearing problems, hypertension, stroke). Multivariable logistic regression analysis was conducted to assess the association between chronic physical conditions, multimorbidity ( 2 chronic conditions), and MCI. RESULTS: The prevalence of multimorbidity was 49.8% (95% confidence interval (CI)548.1–51.5%) and of MCI was 15.3% (95% CI514.4–16.3%). After adjustment for potential confounders, edentulism (odds ratio (OR)51.24), arthritis (OR51.24), chronic lung disease (OR51.29), cataract (OR51.33), stroke (OR51.94), hearing problems (OR52.27), and multimorbidity (OR51.40) were significantly associated with MCI. There was a gradual increase in the likelihood of MCI (1 condition: OR51.21, 95% CI51.03–1.42; 4 conditions: OR52.07, 95% CI51.70–2.52). CONCLUSION: These results highlight the need to investigate the underlying mechanisms linking chronic conditions and MCI and whether prevention or treatment of chronic conditions or multimorbidity can reduce the onset of cognitive decline and subsequent dementia, especially in LMICs. |
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Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countriesDisfunção CognitivaCognitive DysfunctionOBJECTIVES: To assess the association between chronic physical conditions and multimorbidity and mild cognitive impairment (MCI) in low- and middle-income countries (LMICs). DESIGN: Nationally representative, cross-sectional, community- based study. SETTING: Six countries that participated in the World Health Organization Study on Global Ageing and Adult Health. PARTICIPANTS: Individuals aged 50 and older (N532,715; mean age 62.1615.6; 51.7% female). MEASUREMENTS: The definition of MCI was based on the recommendations of the National Institute on Ageing and Alzheimer’s Association. Ten chronic conditions were assessed (angina pectoris, arthritis, asthma, cataract, chronic lung disease, diabetes mellitus, edentulism, hearing problems, hypertension, stroke). Multivariable logistic regression analysis was conducted to assess the association between chronic physical conditions, multimorbidity ( 2 chronic conditions), and MCI. RESULTS: The prevalence of multimorbidity was 49.8% (95% confidence interval (CI)548.1–51.5%) and of MCI was 15.3% (95% CI514.4–16.3%). After adjustment for potential confounders, edentulism (odds ratio (OR)51.24), arthritis (OR51.24), chronic lung disease (OR51.29), cataract (OR51.33), stroke (OR51.94), hearing problems (OR52.27), and multimorbidity (OR51.40) were significantly associated with MCI. There was a gradual increase in the likelihood of MCI (1 condition: OR51.21, 95% CI51.03–1.42; 4 conditions: OR52.07, 95% CI51.70–2.52). CONCLUSION: These results highlight the need to investigate the underlying mechanisms linking chronic conditions and MCI and whether prevention or treatment of chronic conditions or multimorbidity can reduce the onset of cognitive decline and subsequent dementia, especially in LMICs.Journal of the American Geriatrics Society2018-05-28T14:17:01Z2018-05-28T14:17:01Z2018-04info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfKOYANAGI, A. et al. Chronic physical conditions, multimorbidity, and mild cognitive impairment in low‐and middle‐income countries. J Am Geriatr Soc., New York, v. 66, n. 4, p. 721-727, apr. 2018.0002-8614http://www.repositorio.ufc.br/handle/riufc/32333Koyanagi, AiLara, ElviraStubbs, BrendonCarvalho, Andre F.Oh, HansStickley, AndrewVeronese, NicolaVancampfort, Davyengreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2021-03-29T19:35:09Zoai:repositorio.ufc.br:riufc/32333Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2024-09-11T18:29:36.794184Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false |
dc.title.none.fl_str_mv |
Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries |
title |
Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries |
spellingShingle |
Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries Koyanagi, Ai Disfunção Cognitiva Cognitive Dysfunction |
title_short |
Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries |
title_full |
Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries |
title_fullStr |
Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries |
title_full_unstemmed |
Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries |
title_sort |
Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-Income countries |
author |
Koyanagi, Ai |
author_facet |
Koyanagi, Ai Lara, Elvira Stubbs, Brendon Carvalho, Andre F. Oh, Hans Stickley, Andrew Veronese, Nicola Vancampfort, Davy |
author_role |
author |
author2 |
Lara, Elvira Stubbs, Brendon Carvalho, Andre F. Oh, Hans Stickley, Andrew Veronese, Nicola Vancampfort, Davy |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Koyanagi, Ai Lara, Elvira Stubbs, Brendon Carvalho, Andre F. Oh, Hans Stickley, Andrew Veronese, Nicola Vancampfort, Davy |
dc.subject.por.fl_str_mv |
Disfunção Cognitiva Cognitive Dysfunction |
topic |
Disfunção Cognitiva Cognitive Dysfunction |
description |
OBJECTIVES: To assess the association between chronic physical conditions and multimorbidity and mild cognitive impairment (MCI) in low- and middle-income countries (LMICs). DESIGN: Nationally representative, cross-sectional, community- based study. SETTING: Six countries that participated in the World Health Organization Study on Global Ageing and Adult Health. PARTICIPANTS: Individuals aged 50 and older (N532,715; mean age 62.1615.6; 51.7% female). MEASUREMENTS: The definition of MCI was based on the recommendations of the National Institute on Ageing and Alzheimer’s Association. Ten chronic conditions were assessed (angina pectoris, arthritis, asthma, cataract, chronic lung disease, diabetes mellitus, edentulism, hearing problems, hypertension, stroke). Multivariable logistic regression analysis was conducted to assess the association between chronic physical conditions, multimorbidity ( 2 chronic conditions), and MCI. RESULTS: The prevalence of multimorbidity was 49.8% (95% confidence interval (CI)548.1–51.5%) and of MCI was 15.3% (95% CI514.4–16.3%). After adjustment for potential confounders, edentulism (odds ratio (OR)51.24), arthritis (OR51.24), chronic lung disease (OR51.29), cataract (OR51.33), stroke (OR51.94), hearing problems (OR52.27), and multimorbidity (OR51.40) were significantly associated with MCI. There was a gradual increase in the likelihood of MCI (1 condition: OR51.21, 95% CI51.03–1.42; 4 conditions: OR52.07, 95% CI51.70–2.52). CONCLUSION: These results highlight the need to investigate the underlying mechanisms linking chronic conditions and MCI and whether prevention or treatment of chronic conditions or multimorbidity can reduce the onset of cognitive decline and subsequent dementia, especially in LMICs. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-05-28T14:17:01Z 2018-05-28T14:17:01Z 2018-04 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
KOYANAGI, A. et al. Chronic physical conditions, multimorbidity, and mild cognitive impairment in low‐and middle‐income countries. J Am Geriatr Soc., New York, v. 66, n. 4, p. 721-727, apr. 2018. 0002-8614 http://www.repositorio.ufc.br/handle/riufc/32333 |
identifier_str_mv |
KOYANAGI, A. et al. Chronic physical conditions, multimorbidity, and mild cognitive impairment in low‐and middle‐income countries. J Am Geriatr Soc., New York, v. 66, n. 4, p. 721-727, apr. 2018. 0002-8614 |
url |
http://www.repositorio.ufc.br/handle/riufc/32333 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Journal of the American Geriatrics Society |
publisher.none.fl_str_mv |
Journal of the American Geriatrics Society |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da Universidade Federal do Ceará (UFC) instname:Universidade Federal do Ceará (UFC) instacron:UFC |
instname_str |
Universidade Federal do Ceará (UFC) |
instacron_str |
UFC |
institution |
UFC |
reponame_str |
Repositório Institucional da Universidade Federal do Ceará (UFC) |
collection |
Repositório Institucional da Universidade Federal do Ceará (UFC) |
repository.name.fl_str_mv |
Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC) |
repository.mail.fl_str_mv |
bu@ufc.br || repositorio@ufc.br |
_version_ |
1813028827277819904 |