Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program

Detalhes bibliográficos
Autor(a) principal: Pimentel, Leonardo Halley Carvalho
Data de Publicação: 2014
Outros Autores: Alencar, Francisco José, Rodrigues, Leonardo Raphael Santos, Sousa, Francisca Cléa Florenço de, Teles, João Batista Mendes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
Texto Completo: http://www.repositorio.ufc.br/handle/riufc/10201
Resumo: The objective of this study was to evaluate the effects of botulinum toxin type A (BTX-A) on spastic foot in stroke patients in a rehabilitation program. Method: Hemiparetic stroke patients (n=21) enrolled in a rehabilitation program were divided into two groups. The first group (n=11) received a total of 300UI BTX-A, and the second group (n=10) received 100 UI BTX-A. All patients were assessed at baseline and 2, 4, 8 and 12 weeks after injection for Modified Ashworth Score, time walking 10 meters, and the Functional Independence Measure (mFIM) motor score. Results: The higher-dose group exhibited a significant improvement in spasticity, and both groups showed an improvement in time walking 10 meters and mFIM, with no significant differences between them. Conclusions: Our findings suggest that gains in gait velocity and functional independence were not correlated to BTX-A dose.
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spelling Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation programAcidente Vascular CerebralThe objective of this study was to evaluate the effects of botulinum toxin type A (BTX-A) on spastic foot in stroke patients in a rehabilitation program. Method: Hemiparetic stroke patients (n=21) enrolled in a rehabilitation program were divided into two groups. The first group (n=11) received a total of 300UI BTX-A, and the second group (n=10) received 100 UI BTX-A. All patients were assessed at baseline and 2, 4, 8 and 12 weeks after injection for Modified Ashworth Score, time walking 10 meters, and the Functional Independence Measure (mFIM) motor score. Results: The higher-dose group exhibited a significant improvement in spasticity, and both groups showed an improvement in time walking 10 meters and mFIM, with no significant differences between them. Conclusions: Our findings suggest that gains in gait velocity and functional independence were not correlated to BTX-A dose.O objetivo deste estudo foi avaliar os efeitos da toxina botulínica tipo A (TXB-A) sobre a espasticidade de membro inferior em pacientes pós-AVE em reabilitação. Método: 21 pacientes hemiparéticos foram divididos em dois grupos que receberam doses de TXB-A de 300UI (Grupo 1) e 100UI (Grupo 2) e foram avaliados antes da injeção e 2, 4, 8 e 12 semanas após, quanto à escala de Ashworth modificada, tempo para andar 10 metros e escore motor da Medida de Independência Funcional (MIFm). Resultados: O grupo que utilizou dose mais alta teve melhora significativa da espasticidade. Ambos os grupos tiveram melhora do tempo para andar 10 metros e da MIFm sem diferença significativa entre eles. Conclusões: A melhora da velocidade de marcha e da independência funcional não foram correlacionadas com a dose de TXB-A na amostra analisada.Arquivos de Neuro-Psiquiatria2014-12-11T14:01:14Z2014-12-11T14:01:14Z2014-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfPIMENTEL, L. H. C. et al. Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program. Arquivos de Neuro-Psiquiatria, São Paulo, v. 72, n. 1, p. 28-32, jan. 2014.0004-282Xhttp://www.repositorio.ufc.br/handle/riufc/10201Pimentel, Leonardo Halley CarvalhoAlencar, Francisco JoséRodrigues, Leonardo Raphael SantosSousa, Francisca Cléa Florenço deTeles, João Batista Mendesengreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2019-01-14T16:49:37Zoai:repositorio.ufc.br:riufc/10201Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2024-09-11T19:02:57.875842Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false
dc.title.none.fl_str_mv Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program
title Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program
spellingShingle Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program
Pimentel, Leonardo Halley Carvalho
Acidente Vascular Cerebral
title_short Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program
title_full Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program
title_fullStr Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program
title_full_unstemmed Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program
title_sort Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program
author Pimentel, Leonardo Halley Carvalho
author_facet Pimentel, Leonardo Halley Carvalho
Alencar, Francisco José
Rodrigues, Leonardo Raphael Santos
Sousa, Francisca Cléa Florenço de
Teles, João Batista Mendes
author_role author
author2 Alencar, Francisco José
Rodrigues, Leonardo Raphael Santos
Sousa, Francisca Cléa Florenço de
Teles, João Batista Mendes
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Pimentel, Leonardo Halley Carvalho
Alencar, Francisco José
Rodrigues, Leonardo Raphael Santos
Sousa, Francisca Cléa Florenço de
Teles, João Batista Mendes
dc.subject.por.fl_str_mv Acidente Vascular Cerebral
topic Acidente Vascular Cerebral
description The objective of this study was to evaluate the effects of botulinum toxin type A (BTX-A) on spastic foot in stroke patients in a rehabilitation program. Method: Hemiparetic stroke patients (n=21) enrolled in a rehabilitation program were divided into two groups. The first group (n=11) received a total of 300UI BTX-A, and the second group (n=10) received 100 UI BTX-A. All patients were assessed at baseline and 2, 4, 8 and 12 weeks after injection for Modified Ashworth Score, time walking 10 meters, and the Functional Independence Measure (mFIM) motor score. Results: The higher-dose group exhibited a significant improvement in spasticity, and both groups showed an improvement in time walking 10 meters and mFIM, with no significant differences between them. Conclusions: Our findings suggest that gains in gait velocity and functional independence were not correlated to BTX-A dose.
publishDate 2014
dc.date.none.fl_str_mv 2014-12-11T14:01:14Z
2014-12-11T14:01:14Z
2014-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv PIMENTEL, L. H. C. et al. Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program. Arquivos de Neuro-Psiquiatria, São Paulo, v. 72, n. 1, p. 28-32, jan. 2014.
0004-282X
http://www.repositorio.ufc.br/handle/riufc/10201
identifier_str_mv PIMENTEL, L. H. C. et al. Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program. Arquivos de Neuro-Psiquiatria, São Paulo, v. 72, n. 1, p. 28-32, jan. 2014.
0004-282X
url http://www.repositorio.ufc.br/handle/riufc/10201
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Arquivos de Neuro-Psiquiatria
publisher.none.fl_str_mv Arquivos de Neuro-Psiquiatria
dc.source.none.fl_str_mv reponame:Repositório Institucional da Universidade Federal do Ceará (UFC)
instname:Universidade Federal do Ceará (UFC)
instacron:UFC
instname_str Universidade Federal do Ceará (UFC)
instacron_str UFC
institution UFC
reponame_str Repositório Institucional da Universidade Federal do Ceará (UFC)
collection Repositório Institucional da Universidade Federal do Ceará (UFC)
repository.name.fl_str_mv Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)
repository.mail.fl_str_mv bu@ufc.br || repositorio@ufc.br
_version_ 1813029046363095040

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