Drug interactions resulting from scheduling and errors in the preparation of antibacterials

• Autor(a) principal: Pereira, Francisco Gilberto Fernandes
• Data de Publicação: 2018
• Outros Autores: Melo, Geórgia Alcântara Alencar, Galindo Neto, Nelson Miguel, Carvalho, Rhanna Emanuela Fontenele Lima de, Néri, Eugenie Desirèe Rabelo, Caetano, Joselany Áfio
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
• Texto Completo: http://www.repositorio.ufc.br/handle/riufc/30931
• topic: Anti-Bacterial Agents; Medication Errors; Antibacterianos; Erros de Medicação

Objective: to identify drug interactions resulting from scheduling and errors in the preparation of antibacterials. Methods: observational and cross-sectional study carried out in medical clinics of a sentinel hospital. Data were collected through the observation of prescriptions and the preparation of 265 doses of antibacterials with the use of a check list. Results: the administration of Piperaciclina and Tazobactan prevailed, with 51 doses. The scheduling of antibacterials with another drug occurred predominantly in the morning. Interactions with injectable anticoagulants and between antimicrobials of different classes stood out. The scheduling was associated with the lack of availability of printed guidelines on medication administration (p=0.003). The main error was the dose (32.5%). Conclusion: the scheduling of antibacterials in the medical clinic may potentiate possible drug interactions and dose errors have been identified in the administration of drugs.