Risk factors for death in patients with sepsis in an intensive care unit

Detalhes bibliográficos
Autor(a) principal: Prado, Patricia Rezende do
Data de Publicação: 2018
Outros Autores: Volpáti, Natasha Varjão, Gimenes, Fernanda Raphael Escobar, Atila, Elisabeth, Maggi, Luís Eduardo, Amaral, Thatiana Lameira Maciel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
Texto Completo: http://www.repositorio.ufc.br/handle/riufc/30932
Resumo: Objective: to determine the main risk factors for death in patients with sepsis in an intensive care unit. Methods: it is a retrospective cohort study, wich included 126 patient chorts lhat had clinical and clinical and laboratory diagnosis of sepsis were considered eligible. The conditional probability of death was calculated through the Kaplan-Meier method and the risk of death was estimated by the hazard ratio, using a Cox regression model with p<0.050. Results: a total of 124 patients were included in the study. The main focus of infection was the respiratory system. Regarding the outcome, 40.3% patients with sepsis, 73.9% with severe sepsis and 69.2% with septic shock died. Patients with abdominal sepsis and using vasopressors were at higher risk of death. Conclusion: septic patients with abdominal source of infection and using vasopressor agents had a higher risk of dying, while patients who were tracheostomized had a better chance of living.
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spelling Risk factors for death in patients with sepsis in an intensive care unitFatores de risco para morte em pacientes com sepse em uma unidade de terapia intensivaUnidades de Terapia IntensivaSepseIntensive Care UnitsSepsisObjective: to determine the main risk factors for death in patients with sepsis in an intensive care unit. Methods: it is a retrospective cohort study, wich included 126 patient chorts lhat had clinical and clinical and laboratory diagnosis of sepsis were considered eligible. The conditional probability of death was calculated through the Kaplan-Meier method and the risk of death was estimated by the hazard ratio, using a Cox regression model with p<0.050. Results: a total of 124 patients were included in the study. The main focus of infection was the respiratory system. Regarding the outcome, 40.3% patients with sepsis, 73.9% with severe sepsis and 69.2% with septic shock died. Patients with abdominal sepsis and using vasopressors were at higher risk of death. Conclusion: septic patients with abdominal source of infection and using vasopressor agents had a higher risk of dying, while patients who were tracheostomized had a better chance of living.Objetivo: determinar os principais fatores de risco para a morte em pacientes com sepse em uma unidade de terapia intensiva. Métodos: trata-se de uma coorte retrospectiva, onde foram incluídos 124 prontuários de pacientes que tiveram diagnóstico clínico e laboratorial de sepse. A probabilidade condicional de morte foi calculada através do método de Kaplan-Meier; o risco de morte foi estimado pela razão de risco, utilizando modelo de regressão de Cox com p<0,050. Resultados: o foco principal da infecção foi o sistema respiratório. Em relação ao desfecho, morreram 40,3% pacientes com sepse, 73,9% com sepse grave e 69,2% com choque séptico. Os pacientes com sepse abdominal e que utilizaram vasopressores apresentaram maior risco de morte. Conclusão: pacientes sépticos com fonte abdominal de infecção e fazendo uso de agentes vasopressores apresentaram maior risco de morte, enquanto que pacientes traqueostomizados tiveram melhores chances de sobreviver.Rev Rene2018-04-11T13:37:48Z2018-04-11T13:37:48Z2018info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfPRADO, P. R do et al. Risk factors for death in patients with sepsis in an intensive care unit. Rev Rene, Fortaleza, v. 19, e3231, 2018.2175-6783 (On line)http://www.repositorio.ufc.br/handle/riufc/30932Prado, Patricia Rezende doVolpáti, Natasha VarjãoGimenes, Fernanda Raphael EscobarAtila, ElisabethMaggi, Luís EduardoAmaral, Thatiana Lameira Macielengreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2019-02-04T11:05:21Zoai:repositorio.ufc.br:riufc/30932Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2019-02-04T11:05:21Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false
dc.title.none.fl_str_mv Risk factors for death in patients with sepsis in an intensive care unit
Fatores de risco para morte em pacientes com sepse em uma unidade de terapia intensiva
title Risk factors for death in patients with sepsis in an intensive care unit
spellingShingle Risk factors for death in patients with sepsis in an intensive care unit
Prado, Patricia Rezende do
Unidades de Terapia Intensiva
Sepse
Intensive Care Units
Sepsis
title_short Risk factors for death in patients with sepsis in an intensive care unit
title_full Risk factors for death in patients with sepsis in an intensive care unit
title_fullStr Risk factors for death in patients with sepsis in an intensive care unit
title_full_unstemmed Risk factors for death in patients with sepsis in an intensive care unit
title_sort Risk factors for death in patients with sepsis in an intensive care unit
author Prado, Patricia Rezende do
author_facet Prado, Patricia Rezende do
Volpáti, Natasha Varjão
Gimenes, Fernanda Raphael Escobar
Atila, Elisabeth
Maggi, Luís Eduardo
Amaral, Thatiana Lameira Maciel
author_role author
author2 Volpáti, Natasha Varjão
Gimenes, Fernanda Raphael Escobar
Atila, Elisabeth
Maggi, Luís Eduardo
Amaral, Thatiana Lameira Maciel
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Prado, Patricia Rezende do
Volpáti, Natasha Varjão
Gimenes, Fernanda Raphael Escobar
Atila, Elisabeth
Maggi, Luís Eduardo
Amaral, Thatiana Lameira Maciel
dc.subject.por.fl_str_mv Unidades de Terapia Intensiva
Sepse
Intensive Care Units
Sepsis
topic Unidades de Terapia Intensiva
Sepse
Intensive Care Units
Sepsis
description Objective: to determine the main risk factors for death in patients with sepsis in an intensive care unit. Methods: it is a retrospective cohort study, wich included 126 patient chorts lhat had clinical and clinical and laboratory diagnosis of sepsis were considered eligible. The conditional probability of death was calculated through the Kaplan-Meier method and the risk of death was estimated by the hazard ratio, using a Cox regression model with p<0.050. Results: a total of 124 patients were included in the study. The main focus of infection was the respiratory system. Regarding the outcome, 40.3% patients with sepsis, 73.9% with severe sepsis and 69.2% with septic shock died. Patients with abdominal sepsis and using vasopressors were at higher risk of death. Conclusion: septic patients with abdominal source of infection and using vasopressor agents had a higher risk of dying, while patients who were tracheostomized had a better chance of living.
publishDate 2018
dc.date.none.fl_str_mv 2018-04-11T13:37:48Z
2018-04-11T13:37:48Z
2018
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv PRADO, P. R do et al. Risk factors for death in patients with sepsis in an intensive care unit. Rev Rene, Fortaleza, v. 19, e3231, 2018.
2175-6783 (On line)
http://www.repositorio.ufc.br/handle/riufc/30932
identifier_str_mv PRADO, P. R do et al. Risk factors for death in patients with sepsis in an intensive care unit. Rev Rene, Fortaleza, v. 19, e3231, 2018.
2175-6783 (On line)
url http://www.repositorio.ufc.br/handle/riufc/30932
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Rev Rene
publisher.none.fl_str_mv Rev Rene
dc.source.none.fl_str_mv reponame:Repositório Institucional da Universidade Federal do Ceará (UFC)
instname:Universidade Federal do Ceará (UFC)
instacron:UFC
instname_str Universidade Federal do Ceará (UFC)
instacron_str UFC
institution UFC
reponame_str Repositório Institucional da Universidade Federal do Ceará (UFC)
collection Repositório Institucional da Universidade Federal do Ceará (UFC)
repository.name.fl_str_mv Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)
repository.mail.fl_str_mv bu@ufc.br || repositorio@ufc.br
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