Tuberculose em 228 casos de autópsias
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da Universidade Federal do Ceará (UFC) |
Texto Completo: | http://www.repositorio.ufc.br/handle/riufc/63330 |
Resumo: | Objectives: Tuberculosis is the main cause of death by a single infectious agent in the world. However, few studies have been published about the anatomopathological aspects of tuberculosis (TB) in the organism as a whole. The objective of this article is to analyze the anatomopathological characteristics of deceased patients diagnosed with tuberculosis revealed by autopsy and their relationship with epidemiological and clinical aspects. Methodology: Longitudinal, retrospective, descriptive study of data from records files and reports files of tuberculosis cases from the autopsy at the pathology service of Universidade Federal do Ceará between 1959 and 2015. Results: There were 7236 autopsies with 228 cases of tuberculosis (3.2%). In 39% there was no clinical suspicion of tuberculosis and 16% were suspected. Male gender predominated and an average age of 34.4 years. The most associated diseases were malnutrition (21.1%), Acquired Immunodeficiency Syndrome (AIDS) (16.9%), cancer (11.3%), liver cirrhosis (7.0%). Disseminated tuberculosis occurred in 53.5%, pulmonary in 35.1% and extrapulmonary in 11.4%, the central nervous system was the most affected with meningitis (46.2%) and meningoencephalite (23.1%). Conclusions: Tuberculosis has not been clinically diagnosed in a significant number of cases. Younger age group and more cases in the 1980s and 90s revealed an important association between AIDS and Tuberculosis. Tuberculosis had a varied, complex and severe presentation. |
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Tuberculose em 228 casos de autópsiasTuberculosis in 228 cases of autopsiesTuberculoseAutópsiaDoença TransmissívelObjectives: Tuberculosis is the main cause of death by a single infectious agent in the world. However, few studies have been published about the anatomopathological aspects of tuberculosis (TB) in the organism as a whole. The objective of this article is to analyze the anatomopathological characteristics of deceased patients diagnosed with tuberculosis revealed by autopsy and their relationship with epidemiological and clinical aspects. Methodology: Longitudinal, retrospective, descriptive study of data from records files and reports files of tuberculosis cases from the autopsy at the pathology service of Universidade Federal do Ceará between 1959 and 2015. Results: There were 7236 autopsies with 228 cases of tuberculosis (3.2%). In 39% there was no clinical suspicion of tuberculosis and 16% were suspected. Male gender predominated and an average age of 34.4 years. The most associated diseases were malnutrition (21.1%), Acquired Immunodeficiency Syndrome (AIDS) (16.9%), cancer (11.3%), liver cirrhosis (7.0%). Disseminated tuberculosis occurred in 53.5%, pulmonary in 35.1% and extrapulmonary in 11.4%, the central nervous system was the most affected with meningitis (46.2%) and meningoencephalite (23.1%). Conclusions: Tuberculosis has not been clinically diagnosed in a significant number of cases. Younger age group and more cases in the 1980s and 90s revealed an important association between AIDS and Tuberculosis. Tuberculosis had a varied, complex and severe presentation.Objetivos: tuberculose é a principal causa de morte por um único agente infeccioso no mundo e há poucos trabalhos com autópsia analisando seus aspectos anatomopatológicos. Dessa forma, o objetivo do artigo é analisar características anatomopatológicas de pacientes diagnosticados com tuberculose em autópsia e sua relação com aspectos epidemiológicos e clínicos. Metodologia:estudo longitudinal, retrospectivo, descritivo dos dados dos arquivos de registros e dos arquivos de laudos dos casos de tuberculose do serviço de autópsia do Departamento de Patologia da Universidade Federal do Ceará entre 1959 e 2015. Resultados: foram 7236 autópsias com 228 casos de tuberculose (3,2%). Em 39% não houve suspeita clinicamente de tuberculose e 16% foram suspeitos. Predominou sexo masculino e a média de idade de 34,4 anos. As doenças mais associadas foram desnutrição (21,1 %), Síndrome da Imunodeficiência Adquirida (SIDA) (16,9%), câncer (11,3%), cirrose hepática (7,0%). Tuberculose disseminada ocorreu em 53,5%, pulmonar em 35,1% e extrapulmonar em 11,4%, destes, o sistema nervoso central foi o mais afetado com meningite (46,2%) e meningoencefalite (23,1%). Conclusões: Tuberculose não foi clinicamente diagnosticada em uma quantidade importante de casos. Faixa etária mais jovem e mais casos nas décadas de 80 e 90 revelou a importante associação entre SIDA e tuberculose. A tuberculose teve apresentação variada, complexa e grave.Revista de Medicina da UFC2022-01-05T12:01:06Z2022-01-05T12:01:06Z2021info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfFEITOSA, Priscilla Mariana Freitas Aguiar et al. Tuberculose em 228 casos de autópsias. Revista de Medicina da UFC. Fortaleza, 2021. Disponível em: http://periodicos.ufc.br/revistademedicinadaufc/article/view/61751/218000 Acesso em: 05/01/22.2447-6595http://www.repositorio.ufc.br/handle/riufc/63330Feitosa, Priscilla Mariana Freitas AguiarFerreira, Márcia Valéria PitombeiraSilveira, Renan Siebra CapibaribeQueiroz, Thamiris Silva deAguiar, Lily FerreiraCarvalho, Letícia Neves Solonporreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2022-01-05T12:01:06Zoai:repositorio.ufc.br:riufc/63330Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2022-01-05T12:01:06Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false |
dc.title.none.fl_str_mv |
Tuberculose em 228 casos de autópsias Tuberculosis in 228 cases of autopsies |
title |
Tuberculose em 228 casos de autópsias |
spellingShingle |
Tuberculose em 228 casos de autópsias Feitosa, Priscilla Mariana Freitas Aguiar Tuberculose Autópsia Doença Transmissível |
title_short |
Tuberculose em 228 casos de autópsias |
title_full |
Tuberculose em 228 casos de autópsias |
title_fullStr |
Tuberculose em 228 casos de autópsias |
title_full_unstemmed |
Tuberculose em 228 casos de autópsias |
title_sort |
Tuberculose em 228 casos de autópsias |
author |
Feitosa, Priscilla Mariana Freitas Aguiar |
author_facet |
Feitosa, Priscilla Mariana Freitas Aguiar Ferreira, Márcia Valéria Pitombeira Silveira, Renan Siebra Capibaribe Queiroz, Thamiris Silva de Aguiar, Lily Ferreira Carvalho, Letícia Neves Solon |
author_role |
author |
author2 |
Ferreira, Márcia Valéria Pitombeira Silveira, Renan Siebra Capibaribe Queiroz, Thamiris Silva de Aguiar, Lily Ferreira Carvalho, Letícia Neves Solon |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Feitosa, Priscilla Mariana Freitas Aguiar Ferreira, Márcia Valéria Pitombeira Silveira, Renan Siebra Capibaribe Queiroz, Thamiris Silva de Aguiar, Lily Ferreira Carvalho, Letícia Neves Solon |
dc.subject.por.fl_str_mv |
Tuberculose Autópsia Doença Transmissível |
topic |
Tuberculose Autópsia Doença Transmissível |
description |
Objectives: Tuberculosis is the main cause of death by a single infectious agent in the world. However, few studies have been published about the anatomopathological aspects of tuberculosis (TB) in the organism as a whole. The objective of this article is to analyze the anatomopathological characteristics of deceased patients diagnosed with tuberculosis revealed by autopsy and their relationship with epidemiological and clinical aspects. Methodology: Longitudinal, retrospective, descriptive study of data from records files and reports files of tuberculosis cases from the autopsy at the pathology service of Universidade Federal do Ceará between 1959 and 2015. Results: There were 7236 autopsies with 228 cases of tuberculosis (3.2%). In 39% there was no clinical suspicion of tuberculosis and 16% were suspected. Male gender predominated and an average age of 34.4 years. The most associated diseases were malnutrition (21.1%), Acquired Immunodeficiency Syndrome (AIDS) (16.9%), cancer (11.3%), liver cirrhosis (7.0%). Disseminated tuberculosis occurred in 53.5%, pulmonary in 35.1% and extrapulmonary in 11.4%, the central nervous system was the most affected with meningitis (46.2%) and meningoencephalite (23.1%). Conclusions: Tuberculosis has not been clinically diagnosed in a significant number of cases. Younger age group and more cases in the 1980s and 90s revealed an important association between AIDS and Tuberculosis. Tuberculosis had a varied, complex and severe presentation. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021 2022-01-05T12:01:06Z 2022-01-05T12:01:06Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
FEITOSA, Priscilla Mariana Freitas Aguiar et al. Tuberculose em 228 casos de autópsias. Revista de Medicina da UFC. Fortaleza, 2021. Disponível em: http://periodicos.ufc.br/revistademedicinadaufc/article/view/61751/218000 Acesso em: 05/01/22. 2447-6595 http://www.repositorio.ufc.br/handle/riufc/63330 |
identifier_str_mv |
FEITOSA, Priscilla Mariana Freitas Aguiar et al. Tuberculose em 228 casos de autópsias. Revista de Medicina da UFC. Fortaleza, 2021. Disponível em: http://periodicos.ufc.br/revistademedicinadaufc/article/view/61751/218000 Acesso em: 05/01/22. 2447-6595 |
url |
http://www.repositorio.ufc.br/handle/riufc/63330 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Revista de Medicina da UFC |
publisher.none.fl_str_mv |
Revista de Medicina da UFC |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da Universidade Federal do Ceará (UFC) instname:Universidade Federal do Ceará (UFC) instacron:UFC |
instname_str |
Universidade Federal do Ceará (UFC) |
instacron_str |
UFC |
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UFC |
reponame_str |
Repositório Institucional da Universidade Federal do Ceará (UFC) |
collection |
Repositório Institucional da Universidade Federal do Ceará (UFC) |
repository.name.fl_str_mv |
Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC) |
repository.mail.fl_str_mv |
bu@ufc.br || repositorio@ufc.br |
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1823806703854944256 |