Seroprevalence and spatial distribution dynamics of Yersinia pestis antibodies in dogs and cats from plague foci in the State of Ceará, Northeastern Brazil

Detalhes bibliográficos
Autor(a) principal: Sousa, Larissa Leão Ferrer de
Data de Publicação: 2017
Outros Autores: Alencar, Carlos Henrique Morais de, Almeida, Alzira Maria Paiva de, Cavalcanti, Luciano Pamplona de Góes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
Texto Completo: http://www.repositorio.ufc.br/handle/riufc/29863
Resumo: Introduction: In Brazil, the plague is established in several foci located mainly in the northeastern part of the country, where it alternates between active and quiescent periods. These foci in the State of Ceará have high epidemiological importance. In addition to other plague detection activities, plague areas can be monitored through serological surveys of dogs and cats (domestic carnivores), which, following feeding on plague-infected rodents, can develop mild to severe forms of the disease and produce long-lasting antibodies. This study aimed to characterize the circulation dynamics and spatial distribution of Yersinia pestis antibodies in dogs and cats in plague foci areas of Ceará. Methods: An ecological study was conducted to analyze the temporal series and spatial distribution of secondary data obtained from domestic carnivore serum surveillance in Ceará’s plague areas from 1990 to 2014. Results: Joinpoint analysis revealed that the overall trend was a reduction in antibody-positive animals. The mean proportion of antibody-positivity during the whole study period was 1.5% (3,023/203,311) for dogs, and 0.7% (426/61,135) for cats, with more than 4% antibody-positivity in dogs in 1997 and 2002. Antibody titers ranging from 1/16 to 1/64 were frequent. Despite fluctuations and a significant reduction, in recent years, there were antibody-positive animals annually throughout the study period, and the localities containing antibody-positive animals increased in number. Conclusion: Yersinia pestis is actively circulating in the study areas, posing a danger to the human population.
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spelling Seroprevalence and spatial distribution dynamics of Yersinia pestis antibodies in dogs and cats from plague foci in the State of Ceará, Northeastern BrazilYersinia pestisDistribuição Espacial da PopulaçãoResidence CharacteristicsIntroduction: In Brazil, the plague is established in several foci located mainly in the northeastern part of the country, where it alternates between active and quiescent periods. These foci in the State of Ceará have high epidemiological importance. In addition to other plague detection activities, plague areas can be monitored through serological surveys of dogs and cats (domestic carnivores), which, following feeding on plague-infected rodents, can develop mild to severe forms of the disease and produce long-lasting antibodies. This study aimed to characterize the circulation dynamics and spatial distribution of Yersinia pestis antibodies in dogs and cats in plague foci areas of Ceará. Methods: An ecological study was conducted to analyze the temporal series and spatial distribution of secondary data obtained from domestic carnivore serum surveillance in Ceará’s plague areas from 1990 to 2014. Results: Joinpoint analysis revealed that the overall trend was a reduction in antibody-positive animals. The mean proportion of antibody-positivity during the whole study period was 1.5% (3,023/203,311) for dogs, and 0.7% (426/61,135) for cats, with more than 4% antibody-positivity in dogs in 1997 and 2002. Antibody titers ranging from 1/16 to 1/64 were frequent. Despite fluctuations and a significant reduction, in recent years, there were antibody-positive animals annually throughout the study period, and the localities containing antibody-positive animals increased in number. Conclusion: Yersinia pestis is actively circulating in the study areas, posing a danger to the human population.Revista da Sociedade Brasileira de Medicina Tropical2018-02-22T14:15:01Z2018-02-22T14:15:01Z2017-11info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfSOUSA, L. L. F. de et al. Seroprevalence and spatial distribution dynamics of Yersinia pestis antibodies in dogs and cats from plague foci in the State of Ceará, Northeastern Brazil. Revista da Sociedade Brasileira de Medicina Tropical, v. 50, n. 6, p. 769-776, nov.dez. 2017.0037-86821678-9849 (Online)http://www.repositorio.ufc.br/handle/riufc/29863Sousa, Larissa Leão Ferrer deAlencar, Carlos Henrique Morais deAlmeida, Alzira Maria Paiva deCavalcanti, Luciano Pamplona de Góesengreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2019-01-21T13:15:43Zoai:repositorio.ufc.br:riufc/29863Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2024-09-11T19:03:54.733221Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false
dc.title.none.fl_str_mv Seroprevalence and spatial distribution dynamics of Yersinia pestis antibodies in dogs and cats from plague foci in the State of Ceará, Northeastern Brazil
title Seroprevalence and spatial distribution dynamics of Yersinia pestis antibodies in dogs and cats from plague foci in the State of Ceará, Northeastern Brazil
spellingShingle Seroprevalence and spatial distribution dynamics of Yersinia pestis antibodies in dogs and cats from plague foci in the State of Ceará, Northeastern Brazil
Sousa, Larissa Leão Ferrer de
Yersinia pestis
Distribuição Espacial da População
Residence Characteristics
title_short Seroprevalence and spatial distribution dynamics of Yersinia pestis antibodies in dogs and cats from plague foci in the State of Ceará, Northeastern Brazil
title_full Seroprevalence and spatial distribution dynamics of Yersinia pestis antibodies in dogs and cats from plague foci in the State of Ceará, Northeastern Brazil
title_fullStr Seroprevalence and spatial distribution dynamics of Yersinia pestis antibodies in dogs and cats from plague foci in the State of Ceará, Northeastern Brazil
title_full_unstemmed Seroprevalence and spatial distribution dynamics of Yersinia pestis antibodies in dogs and cats from plague foci in the State of Ceará, Northeastern Brazil
title_sort Seroprevalence and spatial distribution dynamics of Yersinia pestis antibodies in dogs and cats from plague foci in the State of Ceará, Northeastern Brazil
author Sousa, Larissa Leão Ferrer de
author_facet Sousa, Larissa Leão Ferrer de
Alencar, Carlos Henrique Morais de
Almeida, Alzira Maria Paiva de
Cavalcanti, Luciano Pamplona de Góes
author_role author
author2 Alencar, Carlos Henrique Morais de
Almeida, Alzira Maria Paiva de
Cavalcanti, Luciano Pamplona de Góes
author2_role author
author
author
dc.contributor.author.fl_str_mv Sousa, Larissa Leão Ferrer de
Alencar, Carlos Henrique Morais de
Almeida, Alzira Maria Paiva de
Cavalcanti, Luciano Pamplona de Góes
dc.subject.por.fl_str_mv Yersinia pestis
Distribuição Espacial da População
Residence Characteristics
topic Yersinia pestis
Distribuição Espacial da População
Residence Characteristics
description Introduction: In Brazil, the plague is established in several foci located mainly in the northeastern part of the country, where it alternates between active and quiescent periods. These foci in the State of Ceará have high epidemiological importance. In addition to other plague detection activities, plague areas can be monitored through serological surveys of dogs and cats (domestic carnivores), which, following feeding on plague-infected rodents, can develop mild to severe forms of the disease and produce long-lasting antibodies. This study aimed to characterize the circulation dynamics and spatial distribution of Yersinia pestis antibodies in dogs and cats in plague foci areas of Ceará. Methods: An ecological study was conducted to analyze the temporal series and spatial distribution of secondary data obtained from domestic carnivore serum surveillance in Ceará’s plague areas from 1990 to 2014. Results: Joinpoint analysis revealed that the overall trend was a reduction in antibody-positive animals. The mean proportion of antibody-positivity during the whole study period was 1.5% (3,023/203,311) for dogs, and 0.7% (426/61,135) for cats, with more than 4% antibody-positivity in dogs in 1997 and 2002. Antibody titers ranging from 1/16 to 1/64 were frequent. Despite fluctuations and a significant reduction, in recent years, there were antibody-positive animals annually throughout the study period, and the localities containing antibody-positive animals increased in number. Conclusion: Yersinia pestis is actively circulating in the study areas, posing a danger to the human population.
publishDate 2017
dc.date.none.fl_str_mv 2017-11
2018-02-22T14:15:01Z
2018-02-22T14:15:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv SOUSA, L. L. F. de et al. Seroprevalence and spatial distribution dynamics of Yersinia pestis antibodies in dogs and cats from plague foci in the State of Ceará, Northeastern Brazil. Revista da Sociedade Brasileira de Medicina Tropical, v. 50, n. 6, p. 769-776, nov.dez. 2017.
0037-8682
1678-9849 (Online)
http://www.repositorio.ufc.br/handle/riufc/29863
identifier_str_mv SOUSA, L. L. F. de et al. Seroprevalence and spatial distribution dynamics of Yersinia pestis antibodies in dogs and cats from plague foci in the State of Ceará, Northeastern Brazil. Revista da Sociedade Brasileira de Medicina Tropical, v. 50, n. 6, p. 769-776, nov.dez. 2017.
0037-8682
1678-9849 (Online)
url http://www.repositorio.ufc.br/handle/riufc/29863
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical
publisher.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical
dc.source.none.fl_str_mv reponame:Repositório Institucional da Universidade Federal do Ceará (UFC)
instname:Universidade Federal do Ceará (UFC)
instacron:UFC
instname_str Universidade Federal do Ceará (UFC)
instacron_str UFC
institution UFC
reponame_str Repositório Institucional da Universidade Federal do Ceará (UFC)
collection Repositório Institucional da Universidade Federal do Ceará (UFC)
repository.name.fl_str_mv Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)
repository.mail.fl_str_mv bu@ufc.br || repositorio@ufc.br
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