Aspectos toxicológicos da Benzidamina

• Autor(a) principal: Callou, Iana Bantim Felicio
• Data de Publicação: 2014
• Outros Autores: Siqueira, Rafaelly Maria Pinheiro, Carvalho, Mailson Fontes de, Freitas, Ana Paula Fragoso de, Mariz, Saulo Rios, Cerqueira, Gilberto Santos, Freitas, Rivelilson Mendes de
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
• Texto Completo: http://www.repositorio.ufc.br/handle/riufc/10263
• topic: Benzidamina; Transtornos Relacionados ao Uso de Substâncias; Farmacoepidemiologia.

The drug abuse has been the object of several research. Among these substances, the benzydamine is widely used as an anti-inflammatory and as a drug of abuse. We conducted a literature review about the "toxicological aspects of benzydamine”, focusing on clinical issues, both with regard to therapeutic effects as toxic aspects. A literature review was conducted through the databases Pubmed, Scielo, Lilacs and Medline, in which studies were selected, recent and relevant to the discussion of the subject. After analysis of the selected articles, it was found that the benzydamine in high doses causes an increase in production and release of dopamine in the brain, speeding up the activity in the limbic system that controls the functions, such as memory and emotions, causing changes in the perception of reality and consequently visual hallucinations. There is a need to formulate public policies for preventing and combating drug use, associating with a higher accuracy in the dispensing and commercialization of medicine by pharmacies and drugstore.