Active compounds and derivatives of camellia sinensis responding to erosive attacks on dentin

• Autor(a) principal: Passos, Vanara Florêncio
• Data de Publicação: 2018
• Outros Autores: Melo, Mary Anne Sampaio de, Lima, Juliana Paiva Marques, MarçaL, Felipe Franco, Costa, Cecília Atem Gonçalves de Araújo, Rodrigues, Lidiany Karla Azevedo, Santiago, Sérgio Lima
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
• Texto Completo: http://www.repositorio.ufc.br/handle/riufc/34830
• topic: Dentina; Dentin; Tooth Erosion; Erosão Dentária; Metaloproteinases de matriz; Matrix Metalloproteinases

This research explored the potential of Camellia sinensis-derived teas and active compounds to be used as treatments to prevent dentin wear. Human root dentin slabs were randomly assigned to 5 groups (n = 10) as follows: distilled water (DW, control), epigallocatechin-3-gallate (EGCG), theaflavin gallate derivatives (TF), commercial green tea (GT), and commercial black tea (BT). The samples were submitted to a pellicle formation and an erosive cycling model (5x/day, demineralization using 0.01 M hydrochloric acid/60 s) followed by remineralization (human stimulated saliva/60 min) for three days. The samples were treated for 5 min using the test group solutions between the erosive cycles. Dentin changes were assessed with profilometry analysis and FT-Raman spectroscopy. The data regarding wear were analyzed by ANOVA followed by Tukey's test (p < 0.05). EGCG, TF derivatives, and both regular teas significantly suppressed erosive dentin loss (38–47%, p < 0.05). No obvious changes in the Raman spectra were detected in the specimens; however, the DW group had a minor relationship of 2880/2940 cm−1. The phenolic contents in both green and black tea and the important catechins appear to have protective effects on dentin loss.