Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer

Detalhes bibliográficos
Autor(a) principal: Vasques, Paulo Henrique Diógenes
Data de Publicação: 2015
Outros Autores: Alves, Mayara Maia, Aquino, Ranniere Gurgel Furtado de, Torres, Roberto Vitor Almeida, Bezerra, José Lucas Martins, Brasileiro, Luis Porto, Pinheiro, Luiz Gonzaga Porto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
Texto Completo: http://www.repositorio.ufc.br/handle/riufc/18184
Resumo: PURPOSE: To assess the safety and potential equivalence of the use of hemosiderin compared to the Technetium-99 in sentinel lymph node biopsy in human breast cancer. METHODS: Non-random sample of 14 volunteer women diagnosed with breast cancer with primary tumors (T1/T2) and clinically tumor-free axilla were submitted to the identification of sentinel lymph node using hemosiderin obtained from autologous blood injected in the periareolar region 24h before surgery on an outpatient basis. Patients received preoperative subareolar intradermal injection of Technetium-99 in the immediate preoperative period. Patients were submitted to sentinel lymph node biopsy, with incision in the axillary fold guided by Gamma-Probe, dissection by planes until the identification of the point of maximum uptake of Technetium-99, identifying the marked nodes and their colors. All surgical specimens were sent for pathological and immunohistochemical study. RESULTS: The results showed no evidence of side effects and/or allergic and non-allergic reactions in patients submitted to SLNB with hemosiderin. The SLN identification rate per patient was 100%. SLNB identification rate per patient with hemosiderin was the same as that of Technetium, with a concordance rate of 100% between the methods. CONCLUSION: Hemosiderin is a safe dye that is equivalent to Technetium in breast sentinel lymph node biopsy.
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spelling Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancerNeoplasias da MamaHemossiderinaTecnécioPURPOSE: To assess the safety and potential equivalence of the use of hemosiderin compared to the Technetium-99 in sentinel lymph node biopsy in human breast cancer. METHODS: Non-random sample of 14 volunteer women diagnosed with breast cancer with primary tumors (T1/T2) and clinically tumor-free axilla were submitted to the identification of sentinel lymph node using hemosiderin obtained from autologous blood injected in the periareolar region 24h before surgery on an outpatient basis. Patients received preoperative subareolar intradermal injection of Technetium-99 in the immediate preoperative period. Patients were submitted to sentinel lymph node biopsy, with incision in the axillary fold guided by Gamma-Probe, dissection by planes until the identification of the point of maximum uptake of Technetium-99, identifying the marked nodes and their colors. All surgical specimens were sent for pathological and immunohistochemical study. RESULTS: The results showed no evidence of side effects and/or allergic and non-allergic reactions in patients submitted to SLNB with hemosiderin. The SLN identification rate per patient was 100%. SLNB identification rate per patient with hemosiderin was the same as that of Technetium, with a concordance rate of 100% between the methods. CONCLUSION: Hemosiderin is a safe dye that is equivalent to Technetium in breast sentinel lymph node biopsy.Acta Cirúrgica Brasileira2016-07-06T14:20:13Z2016-07-06T14:20:13Z2015info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfVASQUES, Paulo Henrique Diógenes et al. Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer. Acta Cirúrgica Brasileira, São Paulo,v. 30, n. 11, p. 785-790, 2015.Print version 0102-8650On-line version 1678-2674http://www.repositorio.ufc.br/handle/riufc/18184Vasques, Paulo Henrique DiógenesAlves, Mayara MaiaAquino, Ranniere Gurgel Furtado deTorres, Roberto Vitor AlmeidaBezerra, José Lucas MartinsBrasileiro, Luis PortoPinheiro, Luiz Gonzaga Portoengreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2022-08-29T18:29:10Zoai:repositorio.ufc.br:riufc/18184Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2024-09-11T19:00:09.604074Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false
dc.title.none.fl_str_mv Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer
title Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer
spellingShingle Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer
Vasques, Paulo Henrique Diógenes
Neoplasias da Mama
Hemossiderina
Tecnécio
title_short Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer
title_full Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer
title_fullStr Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer
title_full_unstemmed Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer
title_sort Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer
author Vasques, Paulo Henrique Diógenes
author_facet Vasques, Paulo Henrique Diógenes
Alves, Mayara Maia
Aquino, Ranniere Gurgel Furtado de
Torres, Roberto Vitor Almeida
Bezerra, José Lucas Martins
Brasileiro, Luis Porto
Pinheiro, Luiz Gonzaga Porto
author_role author
author2 Alves, Mayara Maia
Aquino, Ranniere Gurgel Furtado de
Torres, Roberto Vitor Almeida
Bezerra, José Lucas Martins
Brasileiro, Luis Porto
Pinheiro, Luiz Gonzaga Porto
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Vasques, Paulo Henrique Diógenes
Alves, Mayara Maia
Aquino, Ranniere Gurgel Furtado de
Torres, Roberto Vitor Almeida
Bezerra, José Lucas Martins
Brasileiro, Luis Porto
Pinheiro, Luiz Gonzaga Porto
dc.subject.por.fl_str_mv Neoplasias da Mama
Hemossiderina
Tecnécio
topic Neoplasias da Mama
Hemossiderina
Tecnécio
description PURPOSE: To assess the safety and potential equivalence of the use of hemosiderin compared to the Technetium-99 in sentinel lymph node biopsy in human breast cancer. METHODS: Non-random sample of 14 volunteer women diagnosed with breast cancer with primary tumors (T1/T2) and clinically tumor-free axilla were submitted to the identification of sentinel lymph node using hemosiderin obtained from autologous blood injected in the periareolar region 24h before surgery on an outpatient basis. Patients received preoperative subareolar intradermal injection of Technetium-99 in the immediate preoperative period. Patients were submitted to sentinel lymph node biopsy, with incision in the axillary fold guided by Gamma-Probe, dissection by planes until the identification of the point of maximum uptake of Technetium-99, identifying the marked nodes and their colors. All surgical specimens were sent for pathological and immunohistochemical study. RESULTS: The results showed no evidence of side effects and/or allergic and non-allergic reactions in patients submitted to SLNB with hemosiderin. The SLN identification rate per patient was 100%. SLNB identification rate per patient with hemosiderin was the same as that of Technetium, with a concordance rate of 100% between the methods. CONCLUSION: Hemosiderin is a safe dye that is equivalent to Technetium in breast sentinel lymph node biopsy.
publishDate 2015
dc.date.none.fl_str_mv 2015
2016-07-06T14:20:13Z
2016-07-06T14:20:13Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv VASQUES, Paulo Henrique Diógenes et al. Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer. Acta Cirúrgica Brasileira, São Paulo,v. 30, n. 11, p. 785-790, 2015.
Print version 0102-8650
On-line version 1678-2674
http://www.repositorio.ufc.br/handle/riufc/18184
identifier_str_mv VASQUES, Paulo Henrique Diógenes et al. Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer. Acta Cirúrgica Brasileira, São Paulo,v. 30, n. 11, p. 785-790, 2015.
Print version 0102-8650
On-line version 1678-2674
url http://www.repositorio.ufc.br/handle/riufc/18184
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Acta Cirúrgica Brasileira
publisher.none.fl_str_mv Acta Cirúrgica Brasileira
dc.source.none.fl_str_mv reponame:Repositório Institucional da Universidade Federal do Ceará (UFC)
instname:Universidade Federal do Ceará (UFC)
instacron:UFC
instname_str Universidade Federal do Ceará (UFC)
instacron_str UFC
institution UFC
reponame_str Repositório Institucional da Universidade Federal do Ceará (UFC)
collection Repositório Institucional da Universidade Federal do Ceará (UFC)
repository.name.fl_str_mv Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)
repository.mail.fl_str_mv bu@ufc.br || repositorio@ufc.br
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