Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da Universidade Federal do Ceará (UFC) |
Texto Completo: | http://www.repositorio.ufc.br/handle/riufc/18184 |
Resumo: | PURPOSE: To assess the safety and potential equivalence of the use of hemosiderin compared to the Technetium-99 in sentinel lymph node biopsy in human breast cancer. METHODS: Non-random sample of 14 volunteer women diagnosed with breast cancer with primary tumors (T1/T2) and clinically tumor-free axilla were submitted to the identification of sentinel lymph node using hemosiderin obtained from autologous blood injected in the periareolar region 24h before surgery on an outpatient basis. Patients received preoperative subareolar intradermal injection of Technetium-99 in the immediate preoperative period. Patients were submitted to sentinel lymph node biopsy, with incision in the axillary fold guided by Gamma-Probe, dissection by planes until the identification of the point of maximum uptake of Technetium-99, identifying the marked nodes and their colors. All surgical specimens were sent for pathological and immunohistochemical study. RESULTS: The results showed no evidence of side effects and/or allergic and non-allergic reactions in patients submitted to SLNB with hemosiderin. The SLN identification rate per patient was 100%. SLNB identification rate per patient with hemosiderin was the same as that of Technetium, with a concordance rate of 100% between the methods. CONCLUSION: Hemosiderin is a safe dye that is equivalent to Technetium in breast sentinel lymph node biopsy. |
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Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancerNeoplasias da MamaHemossiderinaTecnécioPURPOSE: To assess the safety and potential equivalence of the use of hemosiderin compared to the Technetium-99 in sentinel lymph node biopsy in human breast cancer. METHODS: Non-random sample of 14 volunteer women diagnosed with breast cancer with primary tumors (T1/T2) and clinically tumor-free axilla were submitted to the identification of sentinel lymph node using hemosiderin obtained from autologous blood injected in the periareolar region 24h before surgery on an outpatient basis. Patients received preoperative subareolar intradermal injection of Technetium-99 in the immediate preoperative period. Patients were submitted to sentinel lymph node biopsy, with incision in the axillary fold guided by Gamma-Probe, dissection by planes until the identification of the point of maximum uptake of Technetium-99, identifying the marked nodes and their colors. All surgical specimens were sent for pathological and immunohistochemical study. RESULTS: The results showed no evidence of side effects and/or allergic and non-allergic reactions in patients submitted to SLNB with hemosiderin. The SLN identification rate per patient was 100%. SLNB identification rate per patient with hemosiderin was the same as that of Technetium, with a concordance rate of 100% between the methods. CONCLUSION: Hemosiderin is a safe dye that is equivalent to Technetium in breast sentinel lymph node biopsy.Acta Cirúrgica Brasileira2016-07-06T14:20:13Z2016-07-06T14:20:13Z2015info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfVASQUES, Paulo Henrique Diógenes et al. Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer. Acta Cirúrgica Brasileira, São Paulo,v. 30, n. 11, p. 785-790, 2015.Print version 0102-8650On-line version 1678-2674http://www.repositorio.ufc.br/handle/riufc/18184Vasques, Paulo Henrique DiógenesAlves, Mayara MaiaAquino, Ranniere Gurgel Furtado deTorres, Roberto Vitor AlmeidaBezerra, José Lucas MartinsBrasileiro, Luis PortoPinheiro, Luiz Gonzaga Portoengreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2022-08-29T18:29:10Zoai:repositorio.ufc.br:riufc/18184Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2024-09-11T19:00:09.604074Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false |
dc.title.none.fl_str_mv |
Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer |
title |
Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer |
spellingShingle |
Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer Vasques, Paulo Henrique Diógenes Neoplasias da Mama Hemossiderina Tecnécio |
title_short |
Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer |
title_full |
Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer |
title_fullStr |
Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer |
title_full_unstemmed |
Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer |
title_sort |
Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer |
author |
Vasques, Paulo Henrique Diógenes |
author_facet |
Vasques, Paulo Henrique Diógenes Alves, Mayara Maia Aquino, Ranniere Gurgel Furtado de Torres, Roberto Vitor Almeida Bezerra, José Lucas Martins Brasileiro, Luis Porto Pinheiro, Luiz Gonzaga Porto |
author_role |
author |
author2 |
Alves, Mayara Maia Aquino, Ranniere Gurgel Furtado de Torres, Roberto Vitor Almeida Bezerra, José Lucas Martins Brasileiro, Luis Porto Pinheiro, Luiz Gonzaga Porto |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Vasques, Paulo Henrique Diógenes Alves, Mayara Maia Aquino, Ranniere Gurgel Furtado de Torres, Roberto Vitor Almeida Bezerra, José Lucas Martins Brasileiro, Luis Porto Pinheiro, Luiz Gonzaga Porto |
dc.subject.por.fl_str_mv |
Neoplasias da Mama Hemossiderina Tecnécio |
topic |
Neoplasias da Mama Hemossiderina Tecnécio |
description |
PURPOSE: To assess the safety and potential equivalence of the use of hemosiderin compared to the Technetium-99 in sentinel lymph node biopsy in human breast cancer. METHODS: Non-random sample of 14 volunteer women diagnosed with breast cancer with primary tumors (T1/T2) and clinically tumor-free axilla were submitted to the identification of sentinel lymph node using hemosiderin obtained from autologous blood injected in the periareolar region 24h before surgery on an outpatient basis. Patients received preoperative subareolar intradermal injection of Technetium-99 in the immediate preoperative period. Patients were submitted to sentinel lymph node biopsy, with incision in the axillary fold guided by Gamma-Probe, dissection by planes until the identification of the point of maximum uptake of Technetium-99, identifying the marked nodes and their colors. All surgical specimens were sent for pathological and immunohistochemical study. RESULTS: The results showed no evidence of side effects and/or allergic and non-allergic reactions in patients submitted to SLNB with hemosiderin. The SLN identification rate per patient was 100%. SLNB identification rate per patient with hemosiderin was the same as that of Technetium, with a concordance rate of 100% between the methods. CONCLUSION: Hemosiderin is a safe dye that is equivalent to Technetium in breast sentinel lymph node biopsy. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015 2016-07-06T14:20:13Z 2016-07-06T14:20:13Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
VASQUES, Paulo Henrique Diógenes et al. Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer. Acta Cirúrgica Brasileira, São Paulo,v. 30, n. 11, p. 785-790, 2015. Print version 0102-8650 On-line version 1678-2674 http://www.repositorio.ufc.br/handle/riufc/18184 |
identifier_str_mv |
VASQUES, Paulo Henrique Diógenes et al. Comparison between hemosiderin and Technetium-99 in sentinel lymph node biopsy in human breast cancer. Acta Cirúrgica Brasileira, São Paulo,v. 30, n. 11, p. 785-790, 2015. Print version 0102-8650 On-line version 1678-2674 |
url |
http://www.repositorio.ufc.br/handle/riufc/18184 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Acta Cirúrgica Brasileira |
publisher.none.fl_str_mv |
Acta Cirúrgica Brasileira |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da Universidade Federal do Ceará (UFC) instname:Universidade Federal do Ceará (UFC) instacron:UFC |
instname_str |
Universidade Federal do Ceará (UFC) |
instacron_str |
UFC |
institution |
UFC |
reponame_str |
Repositório Institucional da Universidade Federal do Ceará (UFC) |
collection |
Repositório Institucional da Universidade Federal do Ceará (UFC) |
repository.name.fl_str_mv |
Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC) |
repository.mail.fl_str_mv |
bu@ufc.br || repositorio@ufc.br |
_version_ |
1813029029328977920 |