Withanolides isolated from the leaves extract of Acnistus arborescens

Detalhes bibliográficos
Autor(a) principal: Juliane Lira Tavares
Data de Publicação: 2013
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações da UFC
Texto Completo: http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=13107
Resumo: This paper describes the qualitative analysis of the constituents of ethanol extract from leaves of Acnistus arborescens grown in the NÃcleo de Estudos e Pesquisas em Agricultura Urbana (NEPAU), Departamento de Agronomia da Universidade Federal do Cearà (UFC). This study resulted in the development of an analytical method for the isolation and characterization of steroidal lactones, known as withanolides, from the analysis of the extract using chromatographic methods, such as column chromatography (CC), thin layer chromatography (TLC) and high-performance liquid chromatography (HPLC). The isolated compounds had their structures determined by the application of spectroscopic techniques such as nuclear magnetic resonance of hydrogen-1 and carbon-13 (one and two-dimensional) and absorption in the infrared. Thus, it was possible to isolate and identify two vitanolidos previously described in the literature, these being known as Phyalolactone and Withanolide D, and two others withanolides that, according to the literature review done, are considered unique in the literature.
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spelling info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisWithanolides isolated from the leaves extract of Acnistus arborescensVitanolÃdeos isolados a partir do extrato etanÃlico das folhas de acnistus arborescens2013-08-23Daniel Esdras de Andrade Uchoa38887045372http://lattes.cnpq.br/5760515107506923Maria Teresa Salles Trevisan05006874805http://lattes.cnpq.br/9109195307461296Kirley Marques Canuto78980496320http://lattes.cnpq.br/805107961310889202518803386http://lattes.cnpq.br/2980224461930923Juliane Lira TavaresUniversidade Federal do CearÃPrograma de PÃs-GraduaÃÃo em QuÃmica UFCBRAcnistus Arborescens vitanolÃdeos vitaesteroidesAcnistus arborescens withanolides withasteroidsQUIMICA ANALITICAThis paper describes the qualitative analysis of the constituents of ethanol extract from leaves of Acnistus arborescens grown in the NÃcleo de Estudos e Pesquisas em Agricultura Urbana (NEPAU), Departamento de Agronomia da Universidade Federal do Cearà (UFC). This study resulted in the development of an analytical method for the isolation and characterization of steroidal lactones, known as withanolides, from the analysis of the extract using chromatographic methods, such as column chromatography (CC), thin layer chromatography (TLC) and high-performance liquid chromatography (HPLC). The isolated compounds had their structures determined by the application of spectroscopic techniques such as nuclear magnetic resonance of hydrogen-1 and carbon-13 (one and two-dimensional) and absorption in the infrared. Thus, it was possible to isolate and identify two vitanolidos previously described in the literature, these being known as Phyalolactone and Withanolide D, and two others withanolides that, according to the literature review done, are considered unique in the literature.Este trabalho descreve a anÃlise qualitativa dos constituintes do extrato etanÃlico das folhas de Acnistus arborescens cultivada no NÃcleo de Estudos e Pesquisas em Agricultura Urbana (NEPAU), do Departamento de Agronomia da Universidade Federal do CearÃ. Este estudo resultou no desenvolvimento de um mÃtodo analÃtico para isolamento e caracterizaÃÃo de lactonas esteroidais, conhecidas como vitanolÃdeos, a partir da anÃlise do extrato por meio de mÃtodos cromatogrÃficos, como: Cromatografia em Coluna (CC), Cromatografia em Camada Delgada (CCD) e Cromatografia LÃquida de Alta EficiÃncia (CLAE). As substÃncias isoladas tiveram suas estruturas determinadas atravÃs da aplicaÃÃo de tÃcnicas espectroscÃpicas como: RessonÃncia MagnÃtica Nuclear de hidrogÃnio-1 e carbono-13 (uni e bidimensional) e absorÃÃo na regiÃo do infravermelho. Desta forma, foi possÃvel o isolamento e identificaÃÃo de dois vitanolÃdeos jà descritos anteriormente na literatura, sendo estes conhecidos como Fisalolactona e VitanolÃdeo D, alÃm de dois outros vitanolÃdeos os quais, de acordo com o levantamento bibliogrÃfico feito, sÃo considerados inÃditos na literatura. FundaÃÃo Cearense de Apoio ao Desenvolvimento Cientifico e TecnolÃgicoCoordenaÃÃo de AperfeÃoamento de Pessoal de NÃvel Superior http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=13107application/pdfinfo:eu-repo/semantics/openAccessporreponame:Biblioteca Digital de Teses e Dissertações da UFCinstname:Universidade Federal do Cearáinstacron:UFC2019-01-21T11:26:22Zmail@mail.com -
dc.title.en.fl_str_mv Withanolides isolated from the leaves extract of Acnistus arborescens
dc.title.alternative.pt.fl_str_mv VitanolÃdeos isolados a partir do extrato etanÃlico das folhas de acnistus arborescens
title Withanolides isolated from the leaves extract of Acnistus arborescens
spellingShingle Withanolides isolated from the leaves extract of Acnistus arborescens
Juliane Lira Tavares
Acnistus Arborescens
vitanolÃdeos
vitaesteroides
Acnistus arborescens
withanolides
withasteroids
QUIMICA ANALITICA
title_short Withanolides isolated from the leaves extract of Acnistus arborescens
title_full Withanolides isolated from the leaves extract of Acnistus arborescens
title_fullStr Withanolides isolated from the leaves extract of Acnistus arborescens
title_full_unstemmed Withanolides isolated from the leaves extract of Acnistus arborescens
title_sort Withanolides isolated from the leaves extract of Acnistus arborescens
author Juliane Lira Tavares
author_facet Juliane Lira Tavares
author_role author
dc.contributor.advisor1.fl_str_mv Daniel Esdras de Andrade Uchoa
dc.contributor.advisor1ID.fl_str_mv 38887045372
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/5760515107506923
dc.contributor.referee1.fl_str_mv Maria Teresa Salles Trevisan
dc.contributor.referee1ID.fl_str_mv 05006874805
dc.contributor.referee1Lattes.fl_str_mv http://lattes.cnpq.br/9109195307461296
dc.contributor.referee2.fl_str_mv Kirley Marques Canuto
dc.contributor.referee2ID.fl_str_mv 78980496320
dc.contributor.referee2Lattes.fl_str_mv http://lattes.cnpq.br/8051079613108892
dc.contributor.authorID.fl_str_mv 02518803386
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/2980224461930923
dc.contributor.author.fl_str_mv Juliane Lira Tavares
contributor_str_mv Daniel Esdras de Andrade Uchoa
Maria Teresa Salles Trevisan
Kirley Marques Canuto
dc.subject.por.fl_str_mv Acnistus Arborescens
vitanolÃdeos
vitaesteroides
topic Acnistus Arborescens
vitanolÃdeos
vitaesteroides
Acnistus arborescens
withanolides
withasteroids
QUIMICA ANALITICA
dc.subject.eng.fl_str_mv Acnistus arborescens
withanolides
withasteroids
dc.subject.cnpq.fl_str_mv QUIMICA ANALITICA
dc.description.sponsorship.fl_txt_mv FundaÃÃo Cearense de Apoio ao Desenvolvimento Cientifico e TecnolÃgico
CoordenaÃÃo de AperfeÃoamento de Pessoal de NÃvel Superior
dc.description.abstract.por.fl_txt_mv This paper describes the qualitative analysis of the constituents of ethanol extract from leaves of Acnistus arborescens grown in the NÃcleo de Estudos e Pesquisas em Agricultura Urbana (NEPAU), Departamento de Agronomia da Universidade Federal do Cearà (UFC). This study resulted in the development of an analytical method for the isolation and characterization of steroidal lactones, known as withanolides, from the analysis of the extract using chromatographic methods, such as column chromatography (CC), thin layer chromatography (TLC) and high-performance liquid chromatography (HPLC). The isolated compounds had their structures determined by the application of spectroscopic techniques such as nuclear magnetic resonance of hydrogen-1 and carbon-13 (one and two-dimensional) and absorption in the infrared. Thus, it was possible to isolate and identify two vitanolidos previously described in the literature, these being known as Phyalolactone and Withanolide D, and two others withanolides that, according to the literature review done, are considered unique in the literature.
Este trabalho descreve a anÃlise qualitativa dos constituintes do extrato etanÃlico das folhas de Acnistus arborescens cultivada no NÃcleo de Estudos e Pesquisas em Agricultura Urbana (NEPAU), do Departamento de Agronomia da Universidade Federal do CearÃ. Este estudo resultou no desenvolvimento de um mÃtodo analÃtico para isolamento e caracterizaÃÃo de lactonas esteroidais, conhecidas como vitanolÃdeos, a partir da anÃlise do extrato por meio de mÃtodos cromatogrÃficos, como: Cromatografia em Coluna (CC), Cromatografia em Camada Delgada (CCD) e Cromatografia LÃquida de Alta EficiÃncia (CLAE). As substÃncias isoladas tiveram suas estruturas determinadas atravÃs da aplicaÃÃo de tÃcnicas espectroscÃpicas como: RessonÃncia MagnÃtica Nuclear de hidrogÃnio-1 e carbono-13 (uni e bidimensional) e absorÃÃo na regiÃo do infravermelho. Desta forma, foi possÃvel o isolamento e identificaÃÃo de dois vitanolÃdeos jà descritos anteriormente na literatura, sendo estes conhecidos como Fisalolactona e VitanolÃdeo D, alÃm de dois outros vitanolÃdeos os quais, de acordo com o levantamento bibliogrÃfico feito, sÃo considerados inÃditos na literatura.
description This paper describes the qualitative analysis of the constituents of ethanol extract from leaves of Acnistus arborescens grown in the NÃcleo de Estudos e Pesquisas em Agricultura Urbana (NEPAU), Departamento de Agronomia da Universidade Federal do Cearà (UFC). This study resulted in the development of an analytical method for the isolation and characterization of steroidal lactones, known as withanolides, from the analysis of the extract using chromatographic methods, such as column chromatography (CC), thin layer chromatography (TLC) and high-performance liquid chromatography (HPLC). The isolated compounds had their structures determined by the application of spectroscopic techniques such as nuclear magnetic resonance of hydrogen-1 and carbon-13 (one and two-dimensional) and absorption in the infrared. Thus, it was possible to isolate and identify two vitanolidos previously described in the literature, these being known as Phyalolactone and Withanolide D, and two others withanolides that, according to the literature review done, are considered unique in the literature.
publishDate 2013
dc.date.issued.fl_str_mv 2013-08-23
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
status_str publishedVersion
format masterThesis
dc.identifier.uri.fl_str_mv http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=13107
url http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=13107
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal do CearÃ
dc.publisher.program.fl_str_mv Programa de PÃs-GraduaÃÃo em QuÃmica
dc.publisher.initials.fl_str_mv UFC
dc.publisher.country.fl_str_mv BR
publisher.none.fl_str_mv Universidade Federal do CearÃ
dc.source.none.fl_str_mv reponame:Biblioteca Digital de Teses e Dissertações da UFC
instname:Universidade Federal do Ceará
instacron:UFC
reponame_str Biblioteca Digital de Teses e Dissertações da UFC
collection Biblioteca Digital de Teses e Dissertações da UFC
instname_str Universidade Federal do Ceará
instacron_str UFC
institution UFC
repository.name.fl_str_mv -
repository.mail.fl_str_mv mail@mail.com
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