SYNTHESIS AND EVALUATION OF SCHIFF BASE COMPOUNDS AS COPPER AND NICKEL CHELATORS AND RADICAL SCAVENGERS.: SÍNTESE E AVALIAÇÃO DE COMPOSTOS DE BASE DE SCHIFF COMO QUELANTES DE COBRE E NÍQUEL E SEQUESTRADORES DE RADICAIS
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Production Engineering |
Texto Completo: | https://periodicos.ufes.br/bjpe/article/view/28707 |
Resumo: | Several process involving oxidative reactions have a great importance in our routine. Since the antioxidants are very important in diverse industrial areas, three Schiff base compounds were synthetized, characterized (ovalen, valen and dhben) and evaluated for the antioxidant potential acting as radical scavengers and as chelators of transition metals. Their stability constants with Ni(II) and Cu(II) ions were calculated and their antioxidative capacity were determinated by a chelating activity assay and a DPPH method. Dhben shows a greater ability in chelating copper ions than nickel ions in low Schiff base concentrations. Ovalen is also a great chelating agent, being better with nickel than with copper. The results agree with the obtained binding constants 9,09 X 102 L mol-1 for [Cu-dhben] and 9,91 X 102 L mol-1 for [Ni-ovalen]. In DPPH assay, it was observed that dhben and ovalen were capable to decrease DPPH absorbance concentration, however dhben could reach the IC50 even low concentrations. Both dhben and ovalen are good copper and nickel chelating agents, but when it is about free radicals, dhben is the best agent. |
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oai:periodicos.ufes.br:article/28707 |
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UFES-11 |
network_name_str |
Brazilian Journal of Production Engineering |
repository_id_str |
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spelling |
SYNTHESIS AND EVALUATION OF SCHIFF BASE COMPOUNDS AS COPPER AND NICKEL CHELATORS AND RADICAL SCAVENGERS.: SÍNTESE E AVALIAÇÃO DE COMPOSTOS DE BASE DE SCHIFF COMO QUELANTES DE COBRE E NÍQUEL E SEQUESTRADORES DE RADICAISSeveral process involving oxidative reactions have a great importance in our routine. Since the antioxidants are very important in diverse industrial areas, three Schiff base compounds were synthetized, characterized (ovalen, valen and dhben) and evaluated for the antioxidant potential acting as radical scavengers and as chelators of transition metals. Their stability constants with Ni(II) and Cu(II) ions were calculated and their antioxidative capacity were determinated by a chelating activity assay and a DPPH method. Dhben shows a greater ability in chelating copper ions than nickel ions in low Schiff base concentrations. Ovalen is also a great chelating agent, being better with nickel than with copper. The results agree with the obtained binding constants 9,09 X 102 L mol-1 for [Cu-dhben] and 9,91 X 102 L mol-1 for [Ni-ovalen]. In DPPH assay, it was observed that dhben and ovalen were capable to decrease DPPH absorbance concentration, however dhben could reach the IC50 even low concentrations. Both dhben and ovalen are good copper and nickel chelating agents, but when it is about free radicals, dhben is the best agent.Vários processos envolvendo reações oxidativas têm grande importância em nossa rotina. Como os antioxidantes são muito importantes em diversas áreas industriais, três compostos de base de Schiff foram sintetizados, caracterizados (ovalen, valen e dhben) e avaliados quanto ao potencial antioxidante, atuando como sequestradores de radicais e quelantes de metais de transição. Suas constantes de estabilidade com os íons Ni(II) e Cu(II) foram calculadas e sua capacidade antioxidante foi determinada por um ensaio de atividade quelante e pelo método DPPH. O Dhben mostrou uma maior capacidade de quelar íons cobre do que íons níquel em baixas concentrações da base de Schiff. Ovalen também é um ótimo agente quelante, sendo melhor com níquel do que com cobre. Os resultados concordam com as constantes de ligação obtidas 9,09 X 102 L mol-1 para [Cu-dhben] e 9,91 X 102 L mol-1 para [Ni-ovalen]. No ensaio DPPH, observou-se que dhben e ovalen foram capazes de diminuir a concentração de DPPH, no entanto, dhben poderia atingir o IC50 mesmo em baixas concentrações. O dhben e o ovalen são bons agentes quelantes de cobre e níquel, mas quando se trata de radicais livres, o dhben é o melhor agente.Universidade Federal do Espírito Santo - UFES2020-04-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigo avaliado pelos paresapplication/pdfhttps://periodicos.ufes.br/bjpe/article/view/28707Brazilian Journal of Production Engineering; Vol. 6 No. 1 (2020): Número Regular (Janeiro - Março); 38-50Brazilian Journal of Production Engineering; Vol. 6 Núm. 1 (2020): Número Regular (Janeiro - Março); 38-50Brazilian Journal of Production Engineering; v. 6 n. 1 (2020): Número Regular (Janeiro - Março); 38-502447-5580reponame:Brazilian Journal of Production Engineeringinstname:Universidade Federal do Espírito Santo (UFES)instacron:UFESenghttps://periodicos.ufes.br/bjpe/article/view/28707/20653Copyright (c) 2020 Brazilian Journal of Production Engineering - BJPEhttp://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessChagas da Silveira, VivianCosta Cabral Salazar Ramos Moreira, KellyFerreira Martins, LucasMapheu Nogueira, ChristianeOliveira Costa, Ana PaulaFurlan Mendes, Ana Nery2023-02-05T10:33:58Zoai:periodicos.ufes.br:article/28707Revistahttps://periodicos.ufes.br/bjpePUBhttps://periodicos.ufes.br/bjpe/oairodrigo.r.freitas@ufes.br2447-55802447-5580opendoar:2023-02-05T10:33:58Brazilian Journal of Production Engineering - Universidade Federal do Espírito Santo (UFES)false |
dc.title.none.fl_str_mv |
SYNTHESIS AND EVALUATION OF SCHIFF BASE COMPOUNDS AS COPPER AND NICKEL CHELATORS AND RADICAL SCAVENGERS.: SÍNTESE E AVALIAÇÃO DE COMPOSTOS DE BASE DE SCHIFF COMO QUELANTES DE COBRE E NÍQUEL E SEQUESTRADORES DE RADICAIS |
title |
SYNTHESIS AND EVALUATION OF SCHIFF BASE COMPOUNDS AS COPPER AND NICKEL CHELATORS AND RADICAL SCAVENGERS.: SÍNTESE E AVALIAÇÃO DE COMPOSTOS DE BASE DE SCHIFF COMO QUELANTES DE COBRE E NÍQUEL E SEQUESTRADORES DE RADICAIS |
spellingShingle |
SYNTHESIS AND EVALUATION OF SCHIFF BASE COMPOUNDS AS COPPER AND NICKEL CHELATORS AND RADICAL SCAVENGERS.: SÍNTESE E AVALIAÇÃO DE COMPOSTOS DE BASE DE SCHIFF COMO QUELANTES DE COBRE E NÍQUEL E SEQUESTRADORES DE RADICAIS Chagas da Silveira, Vivian |
title_short |
SYNTHESIS AND EVALUATION OF SCHIFF BASE COMPOUNDS AS COPPER AND NICKEL CHELATORS AND RADICAL SCAVENGERS.: SÍNTESE E AVALIAÇÃO DE COMPOSTOS DE BASE DE SCHIFF COMO QUELANTES DE COBRE E NÍQUEL E SEQUESTRADORES DE RADICAIS |
title_full |
SYNTHESIS AND EVALUATION OF SCHIFF BASE COMPOUNDS AS COPPER AND NICKEL CHELATORS AND RADICAL SCAVENGERS.: SÍNTESE E AVALIAÇÃO DE COMPOSTOS DE BASE DE SCHIFF COMO QUELANTES DE COBRE E NÍQUEL E SEQUESTRADORES DE RADICAIS |
title_fullStr |
SYNTHESIS AND EVALUATION OF SCHIFF BASE COMPOUNDS AS COPPER AND NICKEL CHELATORS AND RADICAL SCAVENGERS.: SÍNTESE E AVALIAÇÃO DE COMPOSTOS DE BASE DE SCHIFF COMO QUELANTES DE COBRE E NÍQUEL E SEQUESTRADORES DE RADICAIS |
title_full_unstemmed |
SYNTHESIS AND EVALUATION OF SCHIFF BASE COMPOUNDS AS COPPER AND NICKEL CHELATORS AND RADICAL SCAVENGERS.: SÍNTESE E AVALIAÇÃO DE COMPOSTOS DE BASE DE SCHIFF COMO QUELANTES DE COBRE E NÍQUEL E SEQUESTRADORES DE RADICAIS |
title_sort |
SYNTHESIS AND EVALUATION OF SCHIFF BASE COMPOUNDS AS COPPER AND NICKEL CHELATORS AND RADICAL SCAVENGERS.: SÍNTESE E AVALIAÇÃO DE COMPOSTOS DE BASE DE SCHIFF COMO QUELANTES DE COBRE E NÍQUEL E SEQUESTRADORES DE RADICAIS |
author |
Chagas da Silveira, Vivian |
author_facet |
Chagas da Silveira, Vivian Costa Cabral Salazar Ramos Moreira, Kelly Ferreira Martins, Lucas Mapheu Nogueira, Christiane Oliveira Costa, Ana Paula Furlan Mendes, Ana Nery |
author_role |
author |
author2 |
Costa Cabral Salazar Ramos Moreira, Kelly Ferreira Martins, Lucas Mapheu Nogueira, Christiane Oliveira Costa, Ana Paula Furlan Mendes, Ana Nery |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Chagas da Silveira, Vivian Costa Cabral Salazar Ramos Moreira, Kelly Ferreira Martins, Lucas Mapheu Nogueira, Christiane Oliveira Costa, Ana Paula Furlan Mendes, Ana Nery |
description |
Several process involving oxidative reactions have a great importance in our routine. Since the antioxidants are very important in diverse industrial areas, three Schiff base compounds were synthetized, characterized (ovalen, valen and dhben) and evaluated for the antioxidant potential acting as radical scavengers and as chelators of transition metals. Their stability constants with Ni(II) and Cu(II) ions were calculated and their antioxidative capacity were determinated by a chelating activity assay and a DPPH method. Dhben shows a greater ability in chelating copper ions than nickel ions in low Schiff base concentrations. Ovalen is also a great chelating agent, being better with nickel than with copper. The results agree with the obtained binding constants 9,09 X 102 L mol-1 for [Cu-dhben] and 9,91 X 102 L mol-1 for [Ni-ovalen]. In DPPH assay, it was observed that dhben and ovalen were capable to decrease DPPH absorbance concentration, however dhben could reach the IC50 even low concentrations. Both dhben and ovalen are good copper and nickel chelating agents, but when it is about free radicals, dhben is the best agent. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-04-04 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigo avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.ufes.br/bjpe/article/view/28707 |
url |
https://periodicos.ufes.br/bjpe/article/view/28707 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://periodicos.ufes.br/bjpe/article/view/28707/20653 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2020 Brazilian Journal of Production Engineering - BJPE http://creativecommons.org/licenses/by-nc-sa/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2020 Brazilian Journal of Production Engineering - BJPE http://creativecommons.org/licenses/by-nc-sa/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal do Espírito Santo - UFES |
publisher.none.fl_str_mv |
Universidade Federal do Espírito Santo - UFES |
dc.source.none.fl_str_mv |
Brazilian Journal of Production Engineering; Vol. 6 No. 1 (2020): Número Regular (Janeiro - Março); 38-50 Brazilian Journal of Production Engineering; Vol. 6 Núm. 1 (2020): Número Regular (Janeiro - Março); 38-50 Brazilian Journal of Production Engineering; v. 6 n. 1 (2020): Número Regular (Janeiro - Março); 38-50 2447-5580 reponame:Brazilian Journal of Production Engineering instname:Universidade Federal do Espírito Santo (UFES) instacron:UFES |
instname_str |
Universidade Federal do Espírito Santo (UFES) |
instacron_str |
UFES |
institution |
UFES |
reponame_str |
Brazilian Journal of Production Engineering |
collection |
Brazilian Journal of Production Engineering |
repository.name.fl_str_mv |
Brazilian Journal of Production Engineering - Universidade Federal do Espírito Santo (UFES) |
repository.mail.fl_str_mv |
rodrigo.r.freitas@ufes.br |
_version_ |
1797047317681930240 |