Fatores associados à morte precoce por tuberculose no Espírito Santo: um estudo transversal

Detalhes bibliográficos
Autor(a) principal: Ramos, Gláucia Rebeca Barbosa
Data de Publicação: 2023
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da Universidade Federal do Espírito Santo (riUfes)
Texto Completo: http://repositorio.ufes.br/handle/10/12436
Resumo: Introduction: TB cases that end in death represent a challenge to be faced as they reflect failures in the health service. Early death is defined by deaths that occur within 60 days of starting treatment. The main reasons for studying early death from TB are associated with the need to know characteristics that allow establishing strategies to reduce mortality from TB. Objective: To analyze the factors associated with early death from tuberculosis, in Espírito Santo, from 2015 to 2019. Methodology: Cross-sectional study conducted using linkage between the Sinan and SIM databases. Pearson's chi-square test was performed to determine the proportions of variables in the cure and early death groups and a hierarchical logistic regression model was performed to determine the determinants associated with them. All analyzes were performed in Stata 14.0 and the results were stored in tables in Excel 16. Results: 229 individuals (77.1% of total deaths) died prematurely from TB. Individuals aged 60 or over (OR: 7.08; 95%CI 2.74 - 18.28), alcoholics (OR: 2.64; 95%CI 1.65 - 4.21), people with diabetes (OR: 1 .97; 95%CI 1.18 - 3.30), mental illness (OR: 2.63; 95%CI 1.08 - 6.42), individuals who did not undergo HIV serology (OR: 7.83; 95%CI 4 .33 - 14.14) and individuals who did not undergo sputum culture (OR: 3.18 95% CI 1.45 - 6.98) had a higher chance of early death from TB when compared to individuals who achieved a cure. Conclusions: The analysis of the sociodemographic and clinical characteristics of deaths allowed us to establish a profile of cases of early death due to TB. The results of this analysis reinforce the need for investment in in-depth studies that aim to develop strategies to improve the infrastructure of the health service offered and equitable access to it. With this, advances will be made in the context of preventing and controlling TB, as well as its complications and deaths.
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spelling Prado, Thiago Nascimento Dohttps://orcid.org/0000000181326288http://lattes.cnpq.br/6388559394015871Ramos, Gláucia Rebeca Barbosahttps://orcid.org/0000-0001-7336-0507http://lattes.cnpq.br/2451722626630471Vieira, Anne Caroline Barbosa CerqueiraSouza, Fernanda Mattos de2024-05-29T20:55:16Z2024-05-29T20:55:16Z2023-10-02Introduction: TB cases that end in death represent a challenge to be faced as they reflect failures in the health service. Early death is defined by deaths that occur within 60 days of starting treatment. The main reasons for studying early death from TB are associated with the need to know characteristics that allow establishing strategies to reduce mortality from TB. Objective: To analyze the factors associated with early death from tuberculosis, in Espírito Santo, from 2015 to 2019. Methodology: Cross-sectional study conducted using linkage between the Sinan and SIM databases. Pearson's chi-square test was performed to determine the proportions of variables in the cure and early death groups and a hierarchical logistic regression model was performed to determine the determinants associated with them. All analyzes were performed in Stata 14.0 and the results were stored in tables in Excel 16. Results: 229 individuals (77.1% of total deaths) died prematurely from TB. Individuals aged 60 or over (OR: 7.08; 95%CI 2.74 - 18.28), alcoholics (OR: 2.64; 95%CI 1.65 - 4.21), people with diabetes (OR: 1 .97; 95%CI 1.18 - 3.30), mental illness (OR: 2.63; 95%CI 1.08 - 6.42), individuals who did not undergo HIV serology (OR: 7.83; 95%CI 4 .33 - 14.14) and individuals who did not undergo sputum culture (OR: 3.18 95% CI 1.45 - 6.98) had a higher chance of early death from TB when compared to individuals who achieved a cure. Conclusions: The analysis of the sociodemographic and clinical characteristics of deaths allowed us to establish a profile of cases of early death due to TB. The results of this analysis reinforce the need for investment in in-depth studies that aim to develop strategies to improve the infrastructure of the health service offered and equitable access to it. With this, advances will be made in the context of preventing and controlling TB, as well as its complications and deaths.Introdução: Casos de TB que têm o óbito como encerramento configuram um desafio a ser enfrentado pois refletem falhas no serviço de saúde. Morte precoce é definida por óbitos que ocorrem em até 60 dias após início do tratamento. As principais razões para estudar a morte precoce por TB estão associadas à necessidade de conhecer características que permitam estabelecer estratégias para redução da mortalidade por TB. Objetivo: Analisar os fatores associados à morte precoce por tuberculose, no Espírito Santo, nos anos 2015 a 2019. Metodologia: Estudo transversal conduzido a partir do linkage entre os bancos de dados do Sinan e do SIM. Foram realizados teste qui-quadrado de Pearson para conhecer as proporções das variáveis nos grupos cura e morte precoce e um modelo de regressão logística hierárquica para conhecer os determinantes associados aos mesmos. Todas as análises foram realizadas no Stata 14.0 e os resultados armazenados em tabelas no Excel 16. Resultados: 229 indivíduos (77,1% do total de óbitos) morreram precocemente por TB. Indivíduos com 60 anos ou mais (OR: 7,08; IC95% 2,74 - 18,28), alcoolistas (OR: 2,64; IC95% 1,65 - 4,21), pessoas com diabetes (OR: 1,97; IC95% 1,18 - 3,30), doença mental (OR: 2,63; IC95% 1,08 - 6,42), indivíduos que não realizaram sorologia HIV (OR: 7,83; IC95% 4,33 - 14,14) e indivíduos que não realizaram cultura de escarro (OR: 3,18 IC95% 1,45 - 6,98) apresentaram maiores chances de morte precoce por TB quando comparado aos indivíduos que alcançaram a cura. Considerações finais: A análise das características sociodemográficas e clínicas dos óbitos permitiu estabelecer um perfil dos casos de morte precoce por TB. Os resultados desta análise reforçam a necessidade de investimento em estudos aprofundados que objetivem o desenvolvimento de estratégias para melhorias na infraestrutura do serviço de saúde ofertado e no acesso equitativo ao mesmo. Com isso, avanços serão logrados no contexto de prevenção e controle da TB, bem como de suas complicações e óbitos.Fundação de Amparo à Pesquisa do Espírito Santo (FAPES)Texthttp://repositorio.ufes.br/handle/10/12436porUniversidade Federal do Espírito SantoMestrado em Saúde ColetivaPrograma de Pós-Graduação em Saúde ColetivaUFESBRCentro de Ciências da SaúdeSaúde ColetivaTuberculoseMorteMortalidadeVigilância epidemiológicaFatores associados à morte precoce por tuberculose no Espírito Santo: um estudo transversalinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da Universidade Federal do Espírito Santo (riUfes)instname:Universidade Federal do Espírito Santo (UFES)instacron:UFESORIGINALEMBARGADO-RESTRITO.pdfapplication/pdf275372http://repositorio.ufes.br/bitstreams/583b19f6-7089-4c4a-846d-d10d6c4c623c/downloadf19515a01cb1c30076d7f7ba8c48dd73MD5110/124362024-08-16 09:08:49.39oai:repositorio.ufes.br:10/12436http://repositorio.ufes.brRepositório InstitucionalPUBhttp://repositorio.ufes.br/oai/requestopendoar:21082024-10-15T18:02:10.896157Repositório Institucional da Universidade Federal do Espírito Santo (riUfes) - Universidade Federal do Espírito Santo (UFES)false
dc.title.none.fl_str_mv Fatores associados à morte precoce por tuberculose no Espírito Santo: um estudo transversal
title Fatores associados à morte precoce por tuberculose no Espírito Santo: um estudo transversal
spellingShingle Fatores associados à morte precoce por tuberculose no Espírito Santo: um estudo transversal
Ramos, Gláucia Rebeca Barbosa
Saúde Coletiva
Tuberculose
Morte
Mortalidade
Vigilância epidemiológica
title_short Fatores associados à morte precoce por tuberculose no Espírito Santo: um estudo transversal
title_full Fatores associados à morte precoce por tuberculose no Espírito Santo: um estudo transversal
title_fullStr Fatores associados à morte precoce por tuberculose no Espírito Santo: um estudo transversal
title_full_unstemmed Fatores associados à morte precoce por tuberculose no Espírito Santo: um estudo transversal
title_sort Fatores associados à morte precoce por tuberculose no Espírito Santo: um estudo transversal
author Ramos, Gláucia Rebeca Barbosa
author_facet Ramos, Gláucia Rebeca Barbosa
author_role author
dc.contributor.authorID.none.fl_str_mv https://orcid.org/0000-0001-7336-0507
dc.contributor.authorLattes.none.fl_str_mv http://lattes.cnpq.br/2451722626630471
dc.contributor.advisor1.fl_str_mv Prado, Thiago Nascimento Do
dc.contributor.advisor1ID.fl_str_mv https://orcid.org/0000000181326288
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/6388559394015871
dc.contributor.author.fl_str_mv Ramos, Gláucia Rebeca Barbosa
dc.contributor.referee1.fl_str_mv Vieira, Anne Caroline Barbosa Cerqueira
dc.contributor.referee2.fl_str_mv Souza, Fernanda Mattos de
contributor_str_mv Prado, Thiago Nascimento Do
Vieira, Anne Caroline Barbosa Cerqueira
Souza, Fernanda Mattos de
dc.subject.cnpq.fl_str_mv Saúde Coletiva
topic Saúde Coletiva
Tuberculose
Morte
Mortalidade
Vigilância epidemiológica
dc.subject.por.fl_str_mv Tuberculose
Morte
Mortalidade
Vigilância epidemiológica
description Introduction: TB cases that end in death represent a challenge to be faced as they reflect failures in the health service. Early death is defined by deaths that occur within 60 days of starting treatment. The main reasons for studying early death from TB are associated with the need to know characteristics that allow establishing strategies to reduce mortality from TB. Objective: To analyze the factors associated with early death from tuberculosis, in Espírito Santo, from 2015 to 2019. Methodology: Cross-sectional study conducted using linkage between the Sinan and SIM databases. Pearson's chi-square test was performed to determine the proportions of variables in the cure and early death groups and a hierarchical logistic regression model was performed to determine the determinants associated with them. All analyzes were performed in Stata 14.0 and the results were stored in tables in Excel 16. Results: 229 individuals (77.1% of total deaths) died prematurely from TB. Individuals aged 60 or over (OR: 7.08; 95%CI 2.74 - 18.28), alcoholics (OR: 2.64; 95%CI 1.65 - 4.21), people with diabetes (OR: 1 .97; 95%CI 1.18 - 3.30), mental illness (OR: 2.63; 95%CI 1.08 - 6.42), individuals who did not undergo HIV serology (OR: 7.83; 95%CI 4 .33 - 14.14) and individuals who did not undergo sputum culture (OR: 3.18 95% CI 1.45 - 6.98) had a higher chance of early death from TB when compared to individuals who achieved a cure. Conclusions: The analysis of the sociodemographic and clinical characteristics of deaths allowed us to establish a profile of cases of early death due to TB. The results of this analysis reinforce the need for investment in in-depth studies that aim to develop strategies to improve the infrastructure of the health service offered and equitable access to it. With this, advances will be made in the context of preventing and controlling TB, as well as its complications and deaths.
publishDate 2023
dc.date.issued.fl_str_mv 2023-10-02
dc.date.accessioned.fl_str_mv 2024-05-29T20:55:16Z
dc.date.available.fl_str_mv 2024-05-29T20:55:16Z
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dc.publisher.none.fl_str_mv Universidade Federal do Espírito Santo
Mestrado em Saúde Coletiva
dc.publisher.program.fl_str_mv Programa de Pós-Graduação em Saúde Coletiva
dc.publisher.initials.fl_str_mv UFES
dc.publisher.country.fl_str_mv BR
dc.publisher.department.fl_str_mv Centro de Ciências da Saúde
publisher.none.fl_str_mv Universidade Federal do Espírito Santo
Mestrado em Saúde Coletiva
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