Preditores do ganho de aptidão cardiorrespiratória em jovens saudáveis: Participação da massa ventricular esquerda

• Autor(a) principal: Sant’Anna, Marcela Lima
• Data de Publicação: 2014
• Tipo de documento: Tese
• Idioma: por
• Título da fonte: Repositório Institucional da Universidade Federal do Espírito Santo (riUfes)
• Texto Completo: http://repositorio.ufes.br/handle/10/8063
• topic: Cardiorespiratory Fitness; Predictors; Maximal Oxygen Uptake; Left Ventricular Mass; Aptidão Cardiorrespiratória; Preditores; Consumo Máximo de oxigênio; Massa Ventricular Esquerda; Fisiologia; 612

Introduction: The cardiorespiratory fitness (CF) is strong and independent predictor of cardiovascular morbidity and mortality in the general population. Although the CF reflects the overall capacity of the cardiovascular and respiratory systems to supply oxygen to the body during prolonged exercise, the relationship between fitness gain and cardiac structure was still poorly investigated. Objective: We assessed the influence of left ventricular mass and function assessed by echocardiography (Echo) on the cardiorespiratory fitness (CF) gain evaluated by ΔVO2max obtained after 16 weeks of aerobic training applied to a healthy group of young males and females. Methods: The CF was evaluated by VO2max measured by ergospirometry and transthoracic Echo. Data were obtained in 89 healthy subjects (73 men and 16 women; age = 23±3 years) before and after 16 weeks of aerobic training. Predictors of ΔVO2max were obtained by univariate and multivariate analysis. Results: The ΔVO2max was associated with gender and baseline measures of VO2max (VO2maxi) (r = - 0,39) and of left ventricular mass index (LVMIi) (r = 0,27). Men had higher ΔVO2max that women, the individuals who presented lower values of VO2maxi and larger values of LVMIi conquered larger ΔVO2max after aerobic training. The multiple linear regression analysis revealed that the ΔVO2max can be modeled by sex, previous CF and LVMIi, explaining 39% of variation of ΔVO2max. In the analysis by sex, the VO2maxi and the LVMIi determine 36% of the variation of ΔVO2max of the men, and in women the predictors observed were VO2maxi and the left ventricular systolic volume (LVSVi) representing 50% determination of the gain of VO2max. Conclusion: We concluded that the left ventricular mass is an important independent predictor of gain cardiorespiratory fitness in healthy young. The response to endurance training is associated with left ventricular physiologically higher in men and with greater stroke volume in women.