Aplicações forenses do Probe Electrospray Ionization Mass Spectrometry com filme de polipirrol
Autor(a) principal: | |
---|---|
Data de Publicação: | 2017 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFG |
Texto Completo: | http://repositorio.bc.ufg.br/tede/handle/tede/7668 |
Resumo: | In this study, we developed a solid phase microextraction (SPME) method to extract Cocaine, Lisergic Acid Diethylamide (LSD), Methamphetamine (MA) and [3,4 – Methylenedioxymethamphetamine] (MDMA), which allowed the direct analysis by MS in a Probe Electrospray Ionization Mass Spectrometry (PESI-MS). PPy fibers were deposited on a platinum wire. These fibers were subjected to drug extraction from biological fluids employing SPME principles. After that, the coated platinum wire was positioned in front of the MS and then a high voltage (HV) was applied on it. At the same time, methanol (formic acid 0,1%) was used to assist the analytes desorption, ionization, and detection. Parameters as number of cycles in electrochemical process, pH, temperature of extraction and matrix effect were evaluated. The coated PESI-MS method presented linearity in a concentration range from the limit of quantification (LOQ) to 500 ng.L-1 (ppb). The LOQ values ranged from 2 ng.L-1 to 10 ng.L-1. The interday precision presented values from 0.8 to 9.6% with accuracy ranging from -0.6 to 13.7%. The intraday precision obtained values varied from 1.7 to 10.8% with accuracy ranging from -2.4 to 14.0%. The absolute recovery was also evaluated and presented values from 97.6 to 114.0%. The proposed method is a promising alternative to fast sampling and analysis for avoiding laborious process, and for showing precision and accuracy according to the values proposed by ANVISA. |
id |
UFG-2_04bc13c512a4a4269983eda0bdbf75bd |
---|---|
oai_identifier_str |
oai:repositorio.bc.ufg.br:tede/7668 |
network_acronym_str |
UFG-2 |
network_name_str |
Repositório Institucional da UFG |
repository_id_str |
|
spelling |
Chaves, Andréa Rodrigueshttp://lattes.cnpq.br/6064014965252121Vaz, Boniek Gontijohttp://lattes.cnpq.br/7814534710550639Chaves, Andréa RodriguesArruda, Andréa FernandesDuarte, Gabriela Rodrigues Mendeshttp://lattes.cnpq.br/4470407084894434Bernardo, Ricardo Alves2017-08-10T13:37:03Z2017-07-14BERNARDO, R. A. Aplicações forenses do Probe Electrospray Ionization Mass Spectrometry com filme de polipirrol. 2017. 82 f. Dissertação (Mestrado em Química) - Universidade Federal de Goiás, Goiânia, 2017.http://repositorio.bc.ufg.br/tede/handle/tede/7668In this study, we developed a solid phase microextraction (SPME) method to extract Cocaine, Lisergic Acid Diethylamide (LSD), Methamphetamine (MA) and [3,4 – Methylenedioxymethamphetamine] (MDMA), which allowed the direct analysis by MS in a Probe Electrospray Ionization Mass Spectrometry (PESI-MS). PPy fibers were deposited on a platinum wire. These fibers were subjected to drug extraction from biological fluids employing SPME principles. After that, the coated platinum wire was positioned in front of the MS and then a high voltage (HV) was applied on it. At the same time, methanol (formic acid 0,1%) was used to assist the analytes desorption, ionization, and detection. Parameters as number of cycles in electrochemical process, pH, temperature of extraction and matrix effect were evaluated. The coated PESI-MS method presented linearity in a concentration range from the limit of quantification (LOQ) to 500 ng.L-1 (ppb). The LOQ values ranged from 2 ng.L-1 to 10 ng.L-1. The interday precision presented values from 0.8 to 9.6% with accuracy ranging from -0.6 to 13.7%. The intraday precision obtained values varied from 1.7 to 10.8% with accuracy ranging from -2.4 to 14.0%. The absolute recovery was also evaluated and presented values from 97.6 to 114.0%. The proposed method is a promising alternative to fast sampling and analysis for avoiding laborious process, and for showing precision and accuracy according to the values proposed by ANVISA.Para este trabalho foi desenvolvido um sistema SPME para extração e análise direta de Cocaína, Dietilamida do Ácido Lisérgico (LSD), [3,4 – Metilenodioximetanfetamina] (MDMA) e Metanfetamina (MA) por espectrometria de massas (MS) em uma fonte de ionização Probe Electrospray Ionization Mass Spectrometry (PESI-MS). Fibras de polipirrol (PPy) foram eletrodepositadas em um fio de platina, essas fibras foram submetidas à extração de drogas em fluidos biológicos empregando os princípios da SPME. Após a extração, o fio de platina contendo o revestimento de PPy foi posicionado na entrada do espectrômetro de massas, uma diferença de potencial (ddp) foi aplicada ao fio e com auxílio de uma solução de metanol (0,1% de ácido fórmico), observou-se a dessorção e detecção dos analitos previamente extraídos. Parâmetros como o número de ciclos de eletrodeposição e pH de extração foram avaliados. O método se mostrou linear na faixa de concentração do LOQ a 500 ng.L-1 (ppb). Os valores de LOQ variaram de 2 ng.L-1 a 10 ng.L-1. A precisão inter-dias do método foi avaliada e mostrou valores entre 0,8 a 9,6% com exatidão de -0,6 a 13,7%. A precisão intra-dias apresentou valores de 1,7 a 10,8% com exatidão de -2,4 a 14.0%. A recuperação do método também foi avaliada e apresentou valores de 97,6 a 114,0%. O método proposto apresenta-se como alternativa promissora para rápida extração e análise direta sem a realização de procedimentos dispendiosos e laboriosos, com precisão e exatidão dentro dos parâmetros propostos pela ANVISA.Submitted by Erika Demachki (erikademachki@gmail.com) on 2017-08-09T19:01:05Z No. of bitstreams: 2 Dissertação - Ricardo Alves Bernardo - 2017.pdf: 2682606 bytes, checksum: f8d1278bd90c5b2d1870dc822ba29d59 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2017-08-10T13:37:03Z (GMT) No. of bitstreams: 2 Dissertação - Ricardo Alves Bernardo - 2017.pdf: 2682606 bytes, checksum: f8d1278bd90c5b2d1870dc822ba29d59 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Made available in DSpace on 2017-08-10T13:37:03Z (GMT). No. of bitstreams: 2 Dissertação - Ricardo Alves Bernardo - 2017.pdf: 2682606 bytes, checksum: f8d1278bd90c5b2d1870dc822ba29d59 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2017-07-14Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESapplication/pdfporUniversidade Federal de GoiásPrograma de Pós-graduação em Química (IQ)UFGBrasilInstituto de Química - IQ (RG)http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessDrogas ilícitasPolipirrolMicroextração em fase sólidaEspectrometria de massasIllicit drugsPolypyrroleSolid phase microextractionMass spectrometryQUIMICA::QUIMICA ANALITICAAplicações forenses do Probe Electrospray Ionization Mass Spectrometry com filme de polipirrolForensic aplications of Probe Electrospray Ionization Mass Spectrometry using polypyrrole filmsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis6636939213254151586006006006007826066743741197278-86616021054614395492075167498588264571reponame:Repositório Institucional da UFGinstname:Universidade Federal de Goiás (UFG)instacron:UFGLICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://repositorio.bc.ufg.br/tede/bitstreams/fd51dc4c-47a5-483f-8d78-53513065c646/downloadbd3efa91386c1718a7f26a329fdcb468MD51CC-LICENSElicense_urllicense_urltext/plain; charset=utf-849http://repositorio.bc.ufg.br/tede/bitstreams/e252cb6a-c44d-452f-9de9-89887b20f19d/download4afdbb8c545fd630ea7db775da747b2fMD52license_textlicense_texttext/html; charset=utf-80http://repositorio.bc.ufg.br/tede/bitstreams/b596d1dc-0527-4ec5-9b17-a2f7ccdfb0f3/downloadd41d8cd98f00b204e9800998ecf8427eMD53license_rdflicense_rdfapplication/rdf+xml; charset=utf-80http://repositorio.bc.ufg.br/tede/bitstreams/261943c1-2cde-453b-ad37-430642029253/downloadd41d8cd98f00b204e9800998ecf8427eMD54ORIGINALDissertação - Ricardo Alves Bernardo - 2017.pdfDissertação - Ricardo Alves Bernardo - 2017.pdfapplication/pdf2682606http://repositorio.bc.ufg.br/tede/bitstreams/af9df889-8477-49f8-890b-fb85d11bdedc/downloadf8d1278bd90c5b2d1870dc822ba29d59MD55tede/76682017-08-10 10:37:03.487http://creativecommons.org/licenses/by-nc-nd/4.0/Acesso Abertoopen.accessoai:repositorio.bc.ufg.br:tede/7668http://repositorio.bc.ufg.br/tedeRepositório InstitucionalPUBhttp://repositorio.bc.ufg.br/oai/requesttasesdissertacoes.bc@ufg.bropendoar:2017-08-10T13:37:03Repositório Institucional da UFG - Universidade Federal de Goiás (UFG)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 |
dc.title.eng.fl_str_mv |
Aplicações forenses do Probe Electrospray Ionization Mass Spectrometry com filme de polipirrol |
dc.title.alternative.eng.fl_str_mv |
Forensic aplications of Probe Electrospray Ionization Mass Spectrometry using polypyrrole films |
title |
Aplicações forenses do Probe Electrospray Ionization Mass Spectrometry com filme de polipirrol |
spellingShingle |
Aplicações forenses do Probe Electrospray Ionization Mass Spectrometry com filme de polipirrol Bernardo, Ricardo Alves Drogas ilícitas Polipirrol Microextração em fase sólida Espectrometria de massas Illicit drugs Polypyrrole Solid phase microextraction Mass spectrometry QUIMICA::QUIMICA ANALITICA |
title_short |
Aplicações forenses do Probe Electrospray Ionization Mass Spectrometry com filme de polipirrol |
title_full |
Aplicações forenses do Probe Electrospray Ionization Mass Spectrometry com filme de polipirrol |
title_fullStr |
Aplicações forenses do Probe Electrospray Ionization Mass Spectrometry com filme de polipirrol |
title_full_unstemmed |
Aplicações forenses do Probe Electrospray Ionization Mass Spectrometry com filme de polipirrol |
title_sort |
Aplicações forenses do Probe Electrospray Ionization Mass Spectrometry com filme de polipirrol |
author |
Bernardo, Ricardo Alves |
author_facet |
Bernardo, Ricardo Alves |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Chaves, Andréa Rodrigues |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/6064014965252121 |
dc.contributor.advisor-co1.fl_str_mv |
Vaz, Boniek Gontijo |
dc.contributor.advisor-co1Lattes.fl_str_mv |
http://lattes.cnpq.br/7814534710550639 |
dc.contributor.referee1.fl_str_mv |
Chaves, Andréa Rodrigues |
dc.contributor.referee2.fl_str_mv |
Arruda, Andréa Fernandes |
dc.contributor.referee3.fl_str_mv |
Duarte, Gabriela Rodrigues Mendes |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/4470407084894434 |
dc.contributor.author.fl_str_mv |
Bernardo, Ricardo Alves |
contributor_str_mv |
Chaves, Andréa Rodrigues Vaz, Boniek Gontijo Chaves, Andréa Rodrigues Arruda, Andréa Fernandes Duarte, Gabriela Rodrigues Mendes |
dc.subject.por.fl_str_mv |
Drogas ilícitas Polipirrol Microextração em fase sólida Espectrometria de massas |
topic |
Drogas ilícitas Polipirrol Microextração em fase sólida Espectrometria de massas Illicit drugs Polypyrrole Solid phase microextraction Mass spectrometry QUIMICA::QUIMICA ANALITICA |
dc.subject.eng.fl_str_mv |
Illicit drugs Polypyrrole Solid phase microextraction Mass spectrometry |
dc.subject.cnpq.fl_str_mv |
QUIMICA::QUIMICA ANALITICA |
description |
In this study, we developed a solid phase microextraction (SPME) method to extract Cocaine, Lisergic Acid Diethylamide (LSD), Methamphetamine (MA) and [3,4 – Methylenedioxymethamphetamine] (MDMA), which allowed the direct analysis by MS in a Probe Electrospray Ionization Mass Spectrometry (PESI-MS). PPy fibers were deposited on a platinum wire. These fibers were subjected to drug extraction from biological fluids employing SPME principles. After that, the coated platinum wire was positioned in front of the MS and then a high voltage (HV) was applied on it. At the same time, methanol (formic acid 0,1%) was used to assist the analytes desorption, ionization, and detection. Parameters as number of cycles in electrochemical process, pH, temperature of extraction and matrix effect were evaluated. The coated PESI-MS method presented linearity in a concentration range from the limit of quantification (LOQ) to 500 ng.L-1 (ppb). The LOQ values ranged from 2 ng.L-1 to 10 ng.L-1. The interday precision presented values from 0.8 to 9.6% with accuracy ranging from -0.6 to 13.7%. The intraday precision obtained values varied from 1.7 to 10.8% with accuracy ranging from -2.4 to 14.0%. The absolute recovery was also evaluated and presented values from 97.6 to 114.0%. The proposed method is a promising alternative to fast sampling and analysis for avoiding laborious process, and for showing precision and accuracy according to the values proposed by ANVISA. |
publishDate |
2017 |
dc.date.accessioned.fl_str_mv |
2017-08-10T13:37:03Z |
dc.date.issued.fl_str_mv |
2017-07-14 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
BERNARDO, R. A. Aplicações forenses do Probe Electrospray Ionization Mass Spectrometry com filme de polipirrol. 2017. 82 f. Dissertação (Mestrado em Química) - Universidade Federal de Goiás, Goiânia, 2017. |
dc.identifier.uri.fl_str_mv |
http://repositorio.bc.ufg.br/tede/handle/tede/7668 |
identifier_str_mv |
BERNARDO, R. A. Aplicações forenses do Probe Electrospray Ionization Mass Spectrometry com filme de polipirrol. 2017. 82 f. Dissertação (Mestrado em Química) - Universidade Federal de Goiás, Goiânia, 2017. |
url |
http://repositorio.bc.ufg.br/tede/handle/tede/7668 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.program.fl_str_mv |
663693921325415158 |
dc.relation.confidence.fl_str_mv |
600 600 600 600 |
dc.relation.department.fl_str_mv |
7826066743741197278 |
dc.relation.cnpq.fl_str_mv |
-8661602105461439549 |
dc.relation.sponsorship.fl_str_mv |
2075167498588264571 |
dc.rights.driver.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.publisher.program.fl_str_mv |
Programa de Pós-graduação em Química (IQ) |
dc.publisher.initials.fl_str_mv |
UFG |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Instituto de Química - IQ (RG) |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFG instname:Universidade Federal de Goiás (UFG) instacron:UFG |
instname_str |
Universidade Federal de Goiás (UFG) |
instacron_str |
UFG |
institution |
UFG |
reponame_str |
Repositório Institucional da UFG |
collection |
Repositório Institucional da UFG |
bitstream.url.fl_str_mv |
http://repositorio.bc.ufg.br/tede/bitstreams/fd51dc4c-47a5-483f-8d78-53513065c646/download http://repositorio.bc.ufg.br/tede/bitstreams/e252cb6a-c44d-452f-9de9-89887b20f19d/download http://repositorio.bc.ufg.br/tede/bitstreams/b596d1dc-0527-4ec5-9b17-a2f7ccdfb0f3/download http://repositorio.bc.ufg.br/tede/bitstreams/261943c1-2cde-453b-ad37-430642029253/download http://repositorio.bc.ufg.br/tede/bitstreams/af9df889-8477-49f8-890b-fb85d11bdedc/download |
bitstream.checksum.fl_str_mv |
bd3efa91386c1718a7f26a329fdcb468 4afdbb8c545fd630ea7db775da747b2f d41d8cd98f00b204e9800998ecf8427e d41d8cd98f00b204e9800998ecf8427e f8d1278bd90c5b2d1870dc822ba29d59 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UFG - Universidade Federal de Goiás (UFG) |
repository.mail.fl_str_mv |
tasesdissertacoes.bc@ufg.br |
_version_ |
1798044336427892736 |