Caracterização de Enterobacteriaceae isoladas da cavidade bucal de trabalhadores de um hospital oncológico: colonização e interfaces com as infecções
Autor(a) principal: | |
---|---|
Data de Publicação: | 2013 |
Tipo de documento: | Tese |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFG |
Texto Completo: | http://repositorio.bc.ufg.br/tede/handle/tede/4299 |
Resumo: | The health care environment presents numerous risks making it anharmful place, propitious to colonization and development of infections. Inserted in this scenario are the healthcare workers which are vulnerable to the carrier condition. and the oral cavity represents an important site of colonization. This study aimed to characterize the phenotype of Enterobacteriaceae isolated from the oral cavity of healthcare workers from an oncologic reference hospital in the central area of Brazil. We also aimed to detect co-colonization by Staphylococcus and Pseudomonas, as well as describe the profile socio-demographic, professional, disease/infection and behavioral of individuals colonized by Enterobacteriaceae. It was a descriptive cross-sectional epidemiological study conducted from May/2009 to November/2010 and saliva was collected a from each subjected. A total of 294 individuals participated in the research, being 149 healthcare members and 145 from the support team. The microbiological procedures were performed according to recommended techniques and data collection obtained by a questionnaire and analyzed through descriptive statistics. Among the participants, 55 (18.7%) were colonized by Enterobacteriaceae in the oral cavity. Were isolated 64 bacteria, including species potentially pathogenic. The most prevalent specie was gergoviae Enterobacter (17.2%). The highest rates of resistance were observed to β-lactams and 48.4% of isolates were considered multiresistant. The Extended Spectrum β-lactamases (ESBL) production was negative for the Enterobacteriaceae and none Klebsiella pneumoniae produced Carbapenemase (KPC). However, among the 43 CESP isolates group (Citrobacter, Enterobacter, Serratia, Providencia), 51.2% produced AmpC β- lactamase by induction and 48.8% were hiper producers. Staphylococcus and Pseudomonas were detected in the saliva of 56.4% individuals. The majory of the healthcare workers colonized by Enterobacteriaceae was men over 40 years. The nursing technician was the professional category most colonized (52.7%), followed by the cleaning staff (23.6%). The cleaning and hygiene sector (23.6%) and nursing stations (18.2%) represented the largest number of workers colonized. Some professionals (27.3%) had second job in another health service, while 41.8% remained in the institution around 40 hours or more a week. Some infection was reported among carriers, as tonsillitis, sinusitis and pharyngitis, being the first the most frequent (52.7%). Enterobacteriaceae carriage (18.2%) reported the use of personal protective equipment (PPE) as unnecessary to their s activity, 7.3% did not use the mask as precautionary measure, 23.6% realized sporadically the exchange of mask and 1.8 % never changed. The use of oral antiseptics was observed in 29.1% of the workers, the recent use of antimicrobials in 16.4% and self-medication in 27.3%. Among the colonized persons was observed lack of knowledge about multiresistant microorganisms. The prevalence Enterobacteriaceae carriage is considered high and the resistance is a problem especially due to multidrug resistance and production of β-lactamase AmpC observed. The results of this research contribute with important subsidies to the programs for nosocomial infections prevention and control of, since knowledge of carrier status reduces the risk of transmission of microorganisms. |
id |
UFG-2_1245cea673f5ae091f9921b481c706b0 |
---|---|
oai_identifier_str |
oai:repositorio.bc.ufg.br:tede/4299 |
network_acronym_str |
UFG-2 |
network_name_str |
Repositório Institucional da UFG |
repository_id_str |
|
spelling |
Pimenta, Fabiana Cristinahttp://lattes.cnpq.br/2230554075502158Vieira, José Daniel GonçalvesVieira, José Daniel GonçalvesPrado-Palos, Marinésia AparecidaRibeiro, Evandro LeãoPereria, Milca SeverinoSouza, Adenícia Custódia Silva ehttp://lattes.cnpq.br/5423949965995995Vasconcelos, Lara Stefânia Netto de Oliveira Leão2015-03-16T21:41:52Z2013-03-28LEÃO-VASCONCELOS, L. S. N. O. Caracterização de Enterobacteriaceae isoladas da cavidade bucal de trabalhadores de um hospital oncológico: colonização e interfaces com as infecções. 2013. 170 f. Tese (Programa de Pós-graduação em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2013.http://repositorio.bc.ufg.br/tede/handle/tede/4299The health care environment presents numerous risks making it anharmful place, propitious to colonization and development of infections. Inserted in this scenario are the healthcare workers which are vulnerable to the carrier condition. and the oral cavity represents an important site of colonization. This study aimed to characterize the phenotype of Enterobacteriaceae isolated from the oral cavity of healthcare workers from an oncologic reference hospital in the central area of Brazil. We also aimed to detect co-colonization by Staphylococcus and Pseudomonas, as well as describe the profile socio-demographic, professional, disease/infection and behavioral of individuals colonized by Enterobacteriaceae. It was a descriptive cross-sectional epidemiological study conducted from May/2009 to November/2010 and saliva was collected a from each subjected. A total of 294 individuals participated in the research, being 149 healthcare members and 145 from the support team. The microbiological procedures were performed according to recommended techniques and data collection obtained by a questionnaire and analyzed through descriptive statistics. Among the participants, 55 (18.7%) were colonized by Enterobacteriaceae in the oral cavity. Were isolated 64 bacteria, including species potentially pathogenic. The most prevalent specie was gergoviae Enterobacter (17.2%). The highest rates of resistance were observed to β-lactams and 48.4% of isolates were considered multiresistant. The Extended Spectrum β-lactamases (ESBL) production was negative for the Enterobacteriaceae and none Klebsiella pneumoniae produced Carbapenemase (KPC). However, among the 43 CESP isolates group (Citrobacter, Enterobacter, Serratia, Providencia), 51.2% produced AmpC β- lactamase by induction and 48.8% were hiper producers. Staphylococcus and Pseudomonas were detected in the saliva of 56.4% individuals. The majory of the healthcare workers colonized by Enterobacteriaceae was men over 40 years. The nursing technician was the professional category most colonized (52.7%), followed by the cleaning staff (23.6%). The cleaning and hygiene sector (23.6%) and nursing stations (18.2%) represented the largest number of workers colonized. Some professionals (27.3%) had second job in another health service, while 41.8% remained in the institution around 40 hours or more a week. Some infection was reported among carriers, as tonsillitis, sinusitis and pharyngitis, being the first the most frequent (52.7%). Enterobacteriaceae carriage (18.2%) reported the use of personal protective equipment (PPE) as unnecessary to their s activity, 7.3% did not use the mask as precautionary measure, 23.6% realized sporadically the exchange of mask and 1.8 % never changed. The use of oral antiseptics was observed in 29.1% of the workers, the recent use of antimicrobials in 16.4% and self-medication in 27.3%. Among the colonized persons was observed lack of knowledge about multiresistant microorganisms. The prevalence Enterobacteriaceae carriage is considered high and the resistance is a problem especially due to multidrug resistance and production of β-lactamase AmpC observed. The results of this research contribute with important subsidies to the programs for nosocomial infections prevention and control of, since knowledge of carrier status reduces the risk of transmission of microorganisms.O ambiente da assistência à saúde apresenta inúmeros riscos que o torna um local insalubre, propício à colonização e ao desenvolvimento de infecções. Inseridos neste cenário estão os trabalhadores dos serviços de saúde, os quais são vulneráveis à condição de portador. A cavidade bucal representa assim um importante sítio de colonização. Este estudo buscou caracterizar o fenótipo de Enterobacteriaceae isoladas da cavidade bucal de trabalhadores de um hospital oncológico referência no Centro-Oeste brasileiro. Também fizeram parte dos objetivos desta pesquisa detectar co-colonização por Staphylococcus e Pseudomonas, bem como descrever o perfil sócio-demográfico, profissional, doença/infecção e comportamental dos indivíduos colonizados por Enterobacteriaceae. Estudo epidemiológico transversal do tipo descritivo realizado de maio/2009 a novembro/2010. Participaram 294 trabalhadores, sendo 149 membros da equipe de saúde e 145 da equipe de apoio. Os procedimentos microbiológicos foram realizados segundo técnicas padronizadas e a coleta de dados realizada por meio da aplicação de um formulário. Foi coletada uma amostra de saliva de cada sujeito Os dados foram analisados por meio de estatística descritiva. Dentre os participantes, 55 (18,7%) estavam colonizados por Enterobacteriaceae na cavidade bucal. Foram isoladas 64 bactérias, incluindo espécies potencialmente patogênicas. A espécie mais prevalente foi Enterobacter gergoviae (17,2%). As maiores taxas de resistências foram observadas para os β-lactâmicos e 48,4% dos isolados foram considerados multirresistentes. Para as enterobactérias pesquisadas, a produção de β-lactamase de Espectro Ampliado (ESBL) e Klebsiella pneumoniae Carbapenemase (KPC) foi negativa. Porém, dentre os 43 isolados do grupo CESP (Citrobacter, Enterobacter, Serratia, Providencia), 51,2% foram considerados produtores de β-lactamase AmpC por indução e 48,8% mutantes hiperprodutores. Staphylococcus e Pseudomonas estavam presentes na saliva de 56,4% dos sujeitos colonizados por Enterobacteriaceae. O maior número de portadores foi constituído por homens acima de 40 anos. Entre os técnicos de enfermagem, 52,7% estavam colonizados, seguidos dos auxiliares de limpeza (23,6%). O setor de higienização e limpeza (23,6%) e os postos de enfermagem (18,2%) contemplaram o maior número de trabalhadores colonizados. Alguns trabalhadores (27,3%) possuíam segundo emprego em outro serviço de saúde, enquanto que 41,8% permaneciam na instituição 40 horas ou mais na semana. Quadros frequentes de infecção foram relatados entre os portadores, como amigdalites, sinusites e faringites, sendo o primeiro o mais frequente (52,7%). Alguns portadores de Enterobacteriaceae (18,2%) relataram o uso de EPI como desnecessário à sua atividade, 7,3% não faziam o uso de máscara como medida de precaução, 23,6% realizavam a troca de máscara esporadicamente e 1,8% nunca trocava. O uso de antissépticos bucais foi observado em 29,1% dos trabalhadores, o uso recente de antimicrobianos em 16,4% e a prática da automedicação em 27,3%. A desinformação sobre micro-organismos multirresistentes foi comum entre os colonizados. A prevalência de portadores de Enterobacteriaceae foi elevada e o fenótipo de resistência dos isolados preocupante, especialmente pela multirresistência e produção de β-lactamases AmpC. As variáveis avaliadas revelaram realidades relevantes para o contexto da assistência à saúde e para a saúde do trabalhador. Os resultados desta pesquisa contribuíram com subsídios importantes para os programas de prevenção e controle das infecções nosocomiais, pois o conhecimento do estado portador reduz os riscos de transmissão de micro-organismos.Submitted by Erika Demachki (erikademachki@gmail.com) on 2015-03-16T21:40:17Z No. of bitstreams: 2 Tese - Lara Stefânia Netto de Oliveira Leão Vasconcelos - 2013.pdf: 3438615 bytes, checksum: 0860846b3615244c0123e230f0e5c789 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)Approved for entry into archive by Erika Demachki (erikademachki@gmail.com) on 2015-03-16T21:41:52Z (GMT) No. of bitstreams: 2 Tese - Lara Stefânia Netto de Oliveira Leão Vasconcelos - 2013.pdf: 3438615 bytes, checksum: 0860846b3615244c0123e230f0e5c789 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)Made available in DSpace on 2015-03-16T21:41:52Z (GMT). No. of bitstreams: 2 Tese - Lara Stefânia Netto de Oliveira Leão Vasconcelos - 2013.pdf: 3438615 bytes, checksum: 0860846b3615244c0123e230f0e5c789 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) Previous issue date: 2013-03-28Fundação de Amparo à Pesquisa do Estado de Goiás - FAPEGapplication/pdfhttp://repositorio.bc.ufg.br/tede/retrieve/17876/Tese%20-%20Lara%20Stef%c3%a2nia%20Netto%20de%20Oliveira%20Le%c3%a3o%20Vasconcelos%20-%202013.pdf.jpgporUniversidade Federal de GoiásPrograma de Pós-graduação em Ciências da Saúde (FM)UFGBrasilFaculdade de Medicina - FM (RG)http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessTrabalhadorPortadorEnterobacteriaceaeMultirresistenteBetalactamasesPerfilWorkersCarrierMultidrug-resistantBeta-lactamasesProfileCIENCIAS DA SAUDECaracterização de Enterobacteriaceae isoladas da cavidade bucal de trabalhadores de um hospital oncológico: colonização e interfaces com as infecçõesCharacterization of Enterobacteriaceae isolated from the oral cavity of workers from a hospital oncology: colonization and interfaces with the infectionsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesis-100686431261774531060060060060015457724759504863388765449414823306929-961409807440757778reponame:Repositório Institucional da UFGinstname:Universidade Federal de Goiás (UFG)instacron:UFGLICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://repositorio.bc.ufg.br/tede/bitstreams/08042ff2-efe0-410f-964f-b931c29f1d95/downloadbd3efa91386c1718a7f26a329fdcb468MD51CC-LICENSElicense_urllicense_urltext/plain; charset=utf-849http://repositorio.bc.ufg.br/tede/bitstreams/a6a2bd15-3386-40dd-87d3-17a6fb60007c/download4afdbb8c545fd630ea7db775da747b2fMD52license_textlicense_texttext/html; charset=utf-822376http://repositorio.bc.ufg.br/tede/bitstreams/f4a349af-4dbc-4cf7-b61c-d585330bbfc7/downloadb292a83e42bd8ad62533bba1395b83ffMD53license_rdflicense_rdfapplication/rdf+xml; charset=utf-823148http://repositorio.bc.ufg.br/tede/bitstreams/a7b38952-86fa-4a7f-b892-11545c17a739/download9da0b6dfac957114c6a7714714b86306MD54ORIGINALTese - Lara Stefânia Netto de Oliveira Leão Vasconcelos - 2013.pdfTese - Lara Stefânia Netto de Oliveira Leão Vasconcelos - 2013.pdfapplication/pdf3438615http://repositorio.bc.ufg.br/tede/bitstreams/4fb77e47-9e5d-44f2-959e-f0d8d7ca468f/download0860846b3615244c0123e230f0e5c789MD55TEXTTese - Lara Stefânia Netto de Oliveira Leão Vasconcelos - 2013.pdf.txtTese - Lara Stefânia Netto de Oliveira Leão Vasconcelos - 2013.pdf.txtExtracted Texttext/plain280261http://repositorio.bc.ufg.br/tede/bitstreams/b0543a2f-84a6-4dca-92bc-0386b7ab2dcc/download40fdb6918c05d4ea3ea46d564f1436bcMD56THUMBNAILTese - Lara Stefânia Netto de Oliveira Leão Vasconcelos - 2013.pdf.jpgTese - Lara Stefânia Netto de Oliveira Leão Vasconcelos - 2013.pdf.jpgGenerated Thumbnailimage/jpeg2635http://repositorio.bc.ufg.br/tede/bitstreams/3a2f6cad-6a5a-4220-a345-2095234892d0/download4205f28ef25a3a9986d7c0337f93b96bMD57tede/42992015-03-17 03:02:14.971http://creativecommons.org/licenses/by-nc-nd/4.0/Acesso Abertoopen.accessoai:repositorio.bc.ufg.br:tede/4299http://repositorio.bc.ufg.br/tedeRepositório InstitucionalPUBhttp://repositorio.bc.ufg.br/oai/requesttasesdissertacoes.bc@ufg.bropendoar:2015-03-17T06:02:14Repositório Institucional da UFG - Universidade Federal de Goiás (UFG)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 |
dc.title.por.fl_str_mv |
Caracterização de Enterobacteriaceae isoladas da cavidade bucal de trabalhadores de um hospital oncológico: colonização e interfaces com as infecções |
dc.title.alternative.eng.fl_str_mv |
Characterization of Enterobacteriaceae isolated from the oral cavity of workers from a hospital oncology: colonization and interfaces with the infections |
title |
Caracterização de Enterobacteriaceae isoladas da cavidade bucal de trabalhadores de um hospital oncológico: colonização e interfaces com as infecções |
spellingShingle |
Caracterização de Enterobacteriaceae isoladas da cavidade bucal de trabalhadores de um hospital oncológico: colonização e interfaces com as infecções Vasconcelos, Lara Stefânia Netto de Oliveira Leão Trabalhador Portador Enterobacteriaceae Multirresistente Betalactamases Perfil Workers Carrier Multidrug-resistant Beta-lactamases Profile CIENCIAS DA SAUDE |
title_short |
Caracterização de Enterobacteriaceae isoladas da cavidade bucal de trabalhadores de um hospital oncológico: colonização e interfaces com as infecções |
title_full |
Caracterização de Enterobacteriaceae isoladas da cavidade bucal de trabalhadores de um hospital oncológico: colonização e interfaces com as infecções |
title_fullStr |
Caracterização de Enterobacteriaceae isoladas da cavidade bucal de trabalhadores de um hospital oncológico: colonização e interfaces com as infecções |
title_full_unstemmed |
Caracterização de Enterobacteriaceae isoladas da cavidade bucal de trabalhadores de um hospital oncológico: colonização e interfaces com as infecções |
title_sort |
Caracterização de Enterobacteriaceae isoladas da cavidade bucal de trabalhadores de um hospital oncológico: colonização e interfaces com as infecções |
author |
Vasconcelos, Lara Stefânia Netto de Oliveira Leão |
author_facet |
Vasconcelos, Lara Stefânia Netto de Oliveira Leão |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Pimenta, Fabiana Cristina |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/2230554075502158 |
dc.contributor.advisor-co1.fl_str_mv |
Vieira, José Daniel Gonçalves |
dc.contributor.referee1.fl_str_mv |
Vieira, José Daniel Gonçalves |
dc.contributor.referee2.fl_str_mv |
Prado-Palos, Marinésia Aparecida |
dc.contributor.referee3.fl_str_mv |
Ribeiro, Evandro Leão |
dc.contributor.referee4.fl_str_mv |
Pereria, Milca Severino |
dc.contributor.referee5.fl_str_mv |
Souza, Adenícia Custódia Silva e |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/5423949965995995 |
dc.contributor.author.fl_str_mv |
Vasconcelos, Lara Stefânia Netto de Oliveira Leão |
contributor_str_mv |
Pimenta, Fabiana Cristina Vieira, José Daniel Gonçalves Vieira, José Daniel Gonçalves Prado-Palos, Marinésia Aparecida Ribeiro, Evandro Leão Pereria, Milca Severino Souza, Adenícia Custódia Silva e |
dc.subject.por.fl_str_mv |
Trabalhador Portador Enterobacteriaceae Multirresistente Betalactamases Perfil |
topic |
Trabalhador Portador Enterobacteriaceae Multirresistente Betalactamases Perfil Workers Carrier Multidrug-resistant Beta-lactamases Profile CIENCIAS DA SAUDE |
dc.subject.eng.fl_str_mv |
Workers Carrier Multidrug-resistant Beta-lactamases Profile |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE |
description |
The health care environment presents numerous risks making it anharmful place, propitious to colonization and development of infections. Inserted in this scenario are the healthcare workers which are vulnerable to the carrier condition. and the oral cavity represents an important site of colonization. This study aimed to characterize the phenotype of Enterobacteriaceae isolated from the oral cavity of healthcare workers from an oncologic reference hospital in the central area of Brazil. We also aimed to detect co-colonization by Staphylococcus and Pseudomonas, as well as describe the profile socio-demographic, professional, disease/infection and behavioral of individuals colonized by Enterobacteriaceae. It was a descriptive cross-sectional epidemiological study conducted from May/2009 to November/2010 and saliva was collected a from each subjected. A total of 294 individuals participated in the research, being 149 healthcare members and 145 from the support team. The microbiological procedures were performed according to recommended techniques and data collection obtained by a questionnaire and analyzed through descriptive statistics. Among the participants, 55 (18.7%) were colonized by Enterobacteriaceae in the oral cavity. Were isolated 64 bacteria, including species potentially pathogenic. The most prevalent specie was gergoviae Enterobacter (17.2%). The highest rates of resistance were observed to β-lactams and 48.4% of isolates were considered multiresistant. The Extended Spectrum β-lactamases (ESBL) production was negative for the Enterobacteriaceae and none Klebsiella pneumoniae produced Carbapenemase (KPC). However, among the 43 CESP isolates group (Citrobacter, Enterobacter, Serratia, Providencia), 51.2% produced AmpC β- lactamase by induction and 48.8% were hiper producers. Staphylococcus and Pseudomonas were detected in the saliva of 56.4% individuals. The majory of the healthcare workers colonized by Enterobacteriaceae was men over 40 years. The nursing technician was the professional category most colonized (52.7%), followed by the cleaning staff (23.6%). The cleaning and hygiene sector (23.6%) and nursing stations (18.2%) represented the largest number of workers colonized. Some professionals (27.3%) had second job in another health service, while 41.8% remained in the institution around 40 hours or more a week. Some infection was reported among carriers, as tonsillitis, sinusitis and pharyngitis, being the first the most frequent (52.7%). Enterobacteriaceae carriage (18.2%) reported the use of personal protective equipment (PPE) as unnecessary to their s activity, 7.3% did not use the mask as precautionary measure, 23.6% realized sporadically the exchange of mask and 1.8 % never changed. The use of oral antiseptics was observed in 29.1% of the workers, the recent use of antimicrobials in 16.4% and self-medication in 27.3%. Among the colonized persons was observed lack of knowledge about multiresistant microorganisms. The prevalence Enterobacteriaceae carriage is considered high and the resistance is a problem especially due to multidrug resistance and production of β-lactamase AmpC observed. The results of this research contribute with important subsidies to the programs for nosocomial infections prevention and control of, since knowledge of carrier status reduces the risk of transmission of microorganisms. |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013-03-28 |
dc.date.accessioned.fl_str_mv |
2015-03-16T21:41:52Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
format |
doctoralThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
LEÃO-VASCONCELOS, L. S. N. O. Caracterização de Enterobacteriaceae isoladas da cavidade bucal de trabalhadores de um hospital oncológico: colonização e interfaces com as infecções. 2013. 170 f. Tese (Programa de Pós-graduação em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2013. |
dc.identifier.uri.fl_str_mv |
http://repositorio.bc.ufg.br/tede/handle/tede/4299 |
identifier_str_mv |
LEÃO-VASCONCELOS, L. S. N. O. Caracterização de Enterobacteriaceae isoladas da cavidade bucal de trabalhadores de um hospital oncológico: colonização e interfaces com as infecções. 2013. 170 f. Tese (Programa de Pós-graduação em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2013. |
url |
http://repositorio.bc.ufg.br/tede/handle/tede/4299 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.program.fl_str_mv |
-1006864312617745310 |
dc.relation.confidence.fl_str_mv |
600 600 600 600 |
dc.relation.department.fl_str_mv |
1545772475950486338 |
dc.relation.cnpq.fl_str_mv |
8765449414823306929 |
dc.relation.sponsorship.fl_str_mv |
-961409807440757778 |
dc.rights.driver.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.publisher.program.fl_str_mv |
Programa de Pós-graduação em Ciências da Saúde (FM) |
dc.publisher.initials.fl_str_mv |
UFG |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Faculdade de Medicina - FM (RG) |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFG instname:Universidade Federal de Goiás (UFG) instacron:UFG |
instname_str |
Universidade Federal de Goiás (UFG) |
instacron_str |
UFG |
institution |
UFG |
reponame_str |
Repositório Institucional da UFG |
collection |
Repositório Institucional da UFG |
bitstream.url.fl_str_mv |
http://repositorio.bc.ufg.br/tede/bitstreams/08042ff2-efe0-410f-964f-b931c29f1d95/download http://repositorio.bc.ufg.br/tede/bitstreams/a6a2bd15-3386-40dd-87d3-17a6fb60007c/download http://repositorio.bc.ufg.br/tede/bitstreams/f4a349af-4dbc-4cf7-b61c-d585330bbfc7/download http://repositorio.bc.ufg.br/tede/bitstreams/a7b38952-86fa-4a7f-b892-11545c17a739/download http://repositorio.bc.ufg.br/tede/bitstreams/4fb77e47-9e5d-44f2-959e-f0d8d7ca468f/download http://repositorio.bc.ufg.br/tede/bitstreams/b0543a2f-84a6-4dca-92bc-0386b7ab2dcc/download http://repositorio.bc.ufg.br/tede/bitstreams/3a2f6cad-6a5a-4220-a345-2095234892d0/download |
bitstream.checksum.fl_str_mv |
bd3efa91386c1718a7f26a329fdcb468 4afdbb8c545fd630ea7db775da747b2f b292a83e42bd8ad62533bba1395b83ff 9da0b6dfac957114c6a7714714b86306 0860846b3615244c0123e230f0e5c789 40fdb6918c05d4ea3ea46d564f1436bc 4205f28ef25a3a9986d7c0337f93b96b |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UFG - Universidade Federal de Goiás (UFG) |
repository.mail.fl_str_mv |
tasesdissertacoes.bc@ufg.br |
_version_ |
1798044384504053760 |