Perfil clínico de pacientes portadores de fibrose cística no interior do estado de Goiás

• Autor(a) principal: Silvestre, Marcela de Andrade
• Data de Publicação: 2018
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Repositório Institucional da UFG
• Texto Completo: http://repositorio.bc.ufg.br/tede/handle/tede/8418
• topic: Fibrose cística; Assistência; Tratamentos; Enfermagem pediátrica; Cystic fibrosis; Assistance; Treatments; Pediatric nursing; ENFERMAGEM::ENFERMAGEM DE SAUDE PUBLICA

Cystic Fibrosis, is an autosomal recessive genetic disease with progressive characteristics, of great pathophysiological complexity and symptomatology. Its impact on quality and life expectancy are significant and conditional upon early diagnosis and treatment. The objective of this study was to describe the population of patients with cystic fibrosis undergoing treatment at a reference unit in the interior of Goiás. Characterization of symptoms, drug treatment and colonization characteristics of these patients. It is a cross-sectional retrospective study. For this purpose, secondary data were collected from 39 charts of patients attended at the reference unit in the state of Goiás. Regarding gender, 48.7% were males and 51.3% were females. Outpatient follow-up was 82.0% and 17.8% were deaths. The causes of death were 100% due to pulmonary complications characteristic of cystic fibrosis. As for the genetic examination, only 30.7% had performed genotyping. Of these, 75% presented the presence of the ΔF508 mutation, being predominantly in heterozygous. The most prevalent symptoms were cough (56.4%), steatorrhea (28.2%), digital clubbing (15.4%) and snoring (15.4%). Regarding the body mass index, 43.6% presented low weight in the first consultation, and in the last consultation this index fell to 25.6%, representing therapeutic adherence. It is possible to emphasize that 28.1% of the patients were gastrostomized and 21.8% were hospitalized at some point in their life. Regarding drug therapy, 89.7% received vitamin supplementation, 79.5% enzymes, 51.3% bronchodilators. The most incident infectious agent in the last consultation and during the life of the patients was Staphilococus aureus with incidence of respectively 56.4% and 66.7%. There was a negative correlation between the values of sodium and alkaline phos- phase (p = 0.002) and sodium with the number of positive cultures (p = 0.005). It is concluded that the correlations observed demonstrate the progressive character of the complaint and it is understood the need for investigations that allow the good use of evaluation criteria and systematized records instruments, optimizing care for these patients. Thus generating important subsidies for the assistance performed by the multiprofessional team to the patient with cystic fibrosis.