Avaliação dos níveis séricos de troponina I em pacientes submetidos à angioplastia coronariana com implante de stent

• Autor(a) principal: VIEIRA, Nancy Helena Lopes da Silva
• Data de Publicação: 2009
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Repositório Institucional da UFG
• Texto Completo: http://repositorio.bc.ufg.br/tede/handle/tde/1770
• topic: Troponina I, Angioplastia coronariana com stent. Marcador cardíaco; Troponin I, Coronary Angioplasty and stents, Cardiac marker; CNPQ::CIENCIAS DA SAUDE

Bakground: The presence of an increase in troponin I (cTnI) is common in patients who have undergone a percutaneous coronary intervention (PCI), but it is questionable if the myocardial lesion occurring in the intervention allows one to identify patients with a greater risk of presenting adverse cardiac events (ACE) .Objective : The overall objective of the study was to evaluate the immediate evolution of cardiac troponin I (cTnI) in patients undergoing elective coronary angioplasty with stenting, and also compare patients with serum changes after the procedure of coronary angioplasty stenting, with the clinical variables and the occurrence of adverse cardiac events (ACE) following 12 months.. Methods: This is a study of a prospective cut, which evaluates 49 consecutive patients who underwent coronary angioplasty with stent implantation. A cTnI serum dosage was done both before and after the procedure. Patients with a cut off >1.0 ng/mL before implantation were excluded. All the others received follow up for one year, to record the presence of ACE (death, acute myocardial infarction, another angioplasty). Results: cTnI serum elevations occurred in 21(45.7%) of the patients after the PCI. At the end of the follow up period, 11(23.9%) of the patients presented adverse cardiac events. There was no association between the cTnI serum elevation and the presence of ACE in the follow up. Conclusions: The elevation of cTnI found after a coronary angioplasty with stent implantation was frequent in our sample, but these elevations in serum did not show any association with clinical variables and the occurrence of adverse cardiac events following 12 months