Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFG |
dARK ID: | ark:/38995/0013000007xmw |
Texto Completo: | http://repositorio.bc.ufg.br/tede/handle/tede/3854 |
Resumo: | Objective: To evaluate the effect of baru almonds supplementation on lipid profile and oxidation state of mildly hypercholesterolemic subjects. Material and Methods: A randomized, controlled and crossover trial was performed with 20 mildly hypercholesterolemic subjects (total cholesterol mean (± SEM) = 5.8 ± 0.2 mmol/L, aged 21–57, and mean body mass index = 23.0 ± 0.5 kg/m2). The assay had 2 periods of 6 wks each and a 4-wk washout period between the treatments. Subjects were randomly allocated in alternated periods receiving the following treatments per period: supplementation with 20 g/d of baru almonds or placebo (1 corn starch capsule/d). Results: Participants maintained their dietary intake throughout the study, except for vitamin E intake that increased after supplementation with baru almonds (P = 0.013). The daily addition of 20 g of baru almonds to the usual diet did not change the volunteers’ body composition neither the oxidation status (P < 0.05). Compared to placebo, supplementation of baru almonds reduced serum total cholesterol (-8.1 ± 2.4%, p = 0.007), LDL-c (-9.4 ± 2.4%, p = 0.006) and non-HDL-c (- 8.1 ± 3.0%, p = 0.013. Conclusions: Diet supplementation of mildly hypercholesterolemic subjects with baru almonds improved serum lipid parameters, so that this food might be included in diets for reducing the cardiovascular disease risk. |
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Naves, Maria Margareth Velosohttp://lattes.cnpq.br/6563181057140270Silva, Mara ReisCominetti, CristianeRogero, Marcelo MacedoHorst, Maria AderuzaNaves, Maria Margareth Velosohttp://lattes.cnpq.br/2585621740520216Bento, Ana Paula Nunes2014-12-30T20:16:50Z2014-03-21BENTO, Ana Paula Nunes. Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos. 2014. 97 f. Dissertação (Mestrado em Nutrição e Saúde) - Universidade Federal de Goiás, Goiânia, 2014.http://repositorio.bc.ufg.br/tede/handle/tede/3854ark:/38995/0013000007xmwObjective: To evaluate the effect of baru almonds supplementation on lipid profile and oxidation state of mildly hypercholesterolemic subjects. Material and Methods: A randomized, controlled and crossover trial was performed with 20 mildly hypercholesterolemic subjects (total cholesterol mean (± SEM) = 5.8 ± 0.2 mmol/L, aged 21–57, and mean body mass index = 23.0 ± 0.5 kg/m2). The assay had 2 periods of 6 wks each and a 4-wk washout period between the treatments. Subjects were randomly allocated in alternated periods receiving the following treatments per period: supplementation with 20 g/d of baru almonds or placebo (1 corn starch capsule/d). Results: Participants maintained their dietary intake throughout the study, except for vitamin E intake that increased after supplementation with baru almonds (P = 0.013). The daily addition of 20 g of baru almonds to the usual diet did not change the volunteers’ body composition neither the oxidation status (P < 0.05). Compared to placebo, supplementation of baru almonds reduced serum total cholesterol (-8.1 ± 2.4%, p = 0.007), LDL-c (-9.4 ± 2.4%, p = 0.006) and non-HDL-c (- 8.1 ± 3.0%, p = 0.013. Conclusions: Diet supplementation of mildly hypercholesterolemic subjects with baru almonds improved serum lipid parameters, so that this food might be included in diets for reducing the cardiovascular disease risk.Objetivo: Avaliar o efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos. Material e métodos: Foi realizado ensaio clínico randomizado, controlado, crossover com 20 indivíduos moderadamente hipercolesterolêmicos (colesterol total 227,3 ± 7,7 mg/dL), com idade variando entre 21 e 57 anos e IMC médio de 23,0 ± 0,5 kg/m2. O ensaio foi composto por duas fases de seis semanas, separadas por um período washout de quatro semanas. Os indivíduos foram randomizados para receber dois tratamentos em fases alternadas definidas por sorteio: 20 g/dia de amêndoa de baru ou placebo (uma cápsula/dia de amido de milho). Avaliação do consumo alimentar, antropometria e exames bioquímicos foram realizadas no início e final de cada fase. Resultados: Os indivíduos mantiveram a ingestão alimentar durante todo o estudo, com exceção da ingestão de vitamina E, que aumentou após a suplementação com a amêndoa de baru (p = 0,013). A adição de 20 g de amêndoa de baru na alimentação habitual dos participantes não alterou a composição corporal e nem o estado oxidativo (p < 0,05). Entretanto, comparado ao tratamento com o placebo, o consumo da amêndoa de baru reduziu as concentrações séricas de colesterol total (- 8.1 ± 2.4%, p = 0.007), de LDL-c (-9.4 ± 2.4%, p = 0.006) e de não-HDL-c (-8.1 ± 3.0%, p = 0.013). Conclusão: A incorporação de amêndoa de baru na dieta de indivíduos com hipercolesterolemia moderada melhorou o perfil lipídico. Sendo assim, a amêndoa de baru pode ser incluída em planos alimentares que visem a redução do risco de doenças cardiovasculares.Submitted by Erika Demachki (erikademachki@gmail.com) on 2014-12-30T20:16:30Z No. of bitstreams: 2 Dissertação - Ana Paula Nunes Bento - 2014.pdf: 7070326 bytes, checksum: 46e239eb41e1e61fb65fd2057c1a9ec6 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)Approved for entry into archive by Erika Demachki (erikademachki@gmail.com) on 2014-12-30T20:16:50Z (GMT) No. of bitstreams: 2 Dissertação - Ana Paula Nunes Bento - 2014.pdf: 7070326 bytes, checksum: 46e239eb41e1e61fb65fd2057c1a9ec6 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)Made available in DSpace on 2014-12-30T20:16:50Z (GMT). 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dc.title.por.fl_str_mv |
Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos |
dc.title.alternative.eng.fl_str_mv |
Effect of baru almond intake in lipid profile and oxidative state of mildly hipercholesterolemic subjects |
title |
Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos |
spellingShingle |
Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos Bento, Ana Paula Nunes Nozes Dislipidemias Estresse oxidativo Doenças cardiovasculares Nuts Dyslipidemias Oxidative stress Cardiovascular diseases CIENCIAS DA SAUDE::NUTRICAO |
title_short |
Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos |
title_full |
Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos |
title_fullStr |
Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos |
title_full_unstemmed |
Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos |
title_sort |
Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos |
author |
Bento, Ana Paula Nunes |
author_facet |
Bento, Ana Paula Nunes |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Naves, Maria Margareth Veloso |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/6563181057140270 |
dc.contributor.advisor-co1.fl_str_mv |
Silva, Mara Reis |
dc.contributor.advisor-co2.fl_str_mv |
Cominetti, Cristiane |
dc.contributor.referee1.fl_str_mv |
Rogero, Marcelo Macedo |
dc.contributor.referee2.fl_str_mv |
Horst, Maria Aderuza |
dc.contributor.referee3.fl_str_mv |
Naves, Maria Margareth Veloso |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/2585621740520216 |
dc.contributor.author.fl_str_mv |
Bento, Ana Paula Nunes |
contributor_str_mv |
Naves, Maria Margareth Veloso Silva, Mara Reis Cominetti, Cristiane Rogero, Marcelo Macedo Horst, Maria Aderuza Naves, Maria Margareth Veloso |
dc.subject.por.fl_str_mv |
Nozes Dislipidemias Estresse oxidativo Doenças cardiovasculares |
topic |
Nozes Dislipidemias Estresse oxidativo Doenças cardiovasculares Nuts Dyslipidemias Oxidative stress Cardiovascular diseases CIENCIAS DA SAUDE::NUTRICAO |
dc.subject.eng.fl_str_mv |
Nuts Dyslipidemias Oxidative stress Cardiovascular diseases |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE::NUTRICAO |
description |
Objective: To evaluate the effect of baru almonds supplementation on lipid profile and oxidation state of mildly hypercholesterolemic subjects. Material and Methods: A randomized, controlled and crossover trial was performed with 20 mildly hypercholesterolemic subjects (total cholesterol mean (± SEM) = 5.8 ± 0.2 mmol/L, aged 21–57, and mean body mass index = 23.0 ± 0.5 kg/m2). The assay had 2 periods of 6 wks each and a 4-wk washout period between the treatments. Subjects were randomly allocated in alternated periods receiving the following treatments per period: supplementation with 20 g/d of baru almonds or placebo (1 corn starch capsule/d). Results: Participants maintained their dietary intake throughout the study, except for vitamin E intake that increased after supplementation with baru almonds (P = 0.013). The daily addition of 20 g of baru almonds to the usual diet did not change the volunteers’ body composition neither the oxidation status (P < 0.05). Compared to placebo, supplementation of baru almonds reduced serum total cholesterol (-8.1 ± 2.4%, p = 0.007), LDL-c (-9.4 ± 2.4%, p = 0.006) and non-HDL-c (- 8.1 ± 3.0%, p = 0.013. Conclusions: Diet supplementation of mildly hypercholesterolemic subjects with baru almonds improved serum lipid parameters, so that this food might be included in diets for reducing the cardiovascular disease risk. |
publishDate |
2014 |
dc.date.accessioned.fl_str_mv |
2014-12-30T20:16:50Z |
dc.date.issued.fl_str_mv |
2014-03-21 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
BENTO, Ana Paula Nunes. Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos. 2014. 97 f. Dissertação (Mestrado em Nutrição e Saúde) - Universidade Federal de Goiás, Goiânia, 2014. |
dc.identifier.uri.fl_str_mv |
http://repositorio.bc.ufg.br/tede/handle/tede/3854 |
dc.identifier.dark.fl_str_mv |
ark:/38995/0013000007xmw |
identifier_str_mv |
BENTO, Ana Paula Nunes. Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos. 2014. 97 f. Dissertação (Mestrado em Nutrição e Saúde) - Universidade Federal de Goiás, Goiânia, 2014. ark:/38995/0013000007xmw |
url |
http://repositorio.bc.ufg.br/tede/handle/tede/3854 |
dc.language.iso.fl_str_mv |
por |
language |
por |
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-3010970718164250106 |
dc.relation.confidence.fl_str_mv |
600 600 600 600 |
dc.relation.department.fl_str_mv |
9028001981735587154 |
dc.relation.cnpq.fl_str_mv |
-1073001350029933100 |
dc.relation.sponsorship.fl_str_mv |
-961409807440757778 |
dc.rights.driver.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess |
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http://creativecommons.org/licenses/by-nc-nd/4.0/ |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.publisher.program.fl_str_mv |
Programa de Pós-graduação em Nutrição e Saúde (FANUT) |
dc.publisher.initials.fl_str_mv |
UFG |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Faculdade de Nutrição - FANUT (RG) |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFG instname:Universidade Federal de Goiás (UFG) instacron:UFG |
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Repositório Institucional da UFG |
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bitstream.checksum.fl_str_mv |
bd3efa91386c1718a7f26a329fdcb468 4afdbb8c545fd630ea7db775da747b2f 29b9d5e95be03707f9d4a2e110421c11 9da0b6dfac957114c6a7714714b86306 46e239eb41e1e61fb65fd2057c1a9ec6 2ae6d40907a5e9550d6267a1d4fe8fbc 33d9d7ff7dd08785a8b045c06f02fef2 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UFG - Universidade Federal de Goiás (UFG) |
repository.mail.fl_str_mv |
tasesdissertacoes.bc@ufg.br |
_version_ |
1813816929214791680 |