Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos

Detalhes bibliográficos
Autor(a) principal: Bento, Ana Paula Nunes
Data de Publicação: 2014
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFG
dARK ID: ark:/38995/0013000007xmw
Texto Completo: http://repositorio.bc.ufg.br/tede/handle/tede/3854
Resumo: Objective: To evaluate the effect of baru almonds supplementation on lipid profile and oxidation state of mildly hypercholesterolemic subjects. Material and Methods: A randomized, controlled and crossover trial was performed with 20 mildly hypercholesterolemic subjects (total cholesterol mean (± SEM) = 5.8 ± 0.2 mmol/L, aged 21–57, and mean body mass index = 23.0 ± 0.5 kg/m2). The assay had 2 periods of 6 wks each and a 4-wk washout period between the treatments. Subjects were randomly allocated in alternated periods receiving the following treatments per period: supplementation with 20 g/d of baru almonds or placebo (1 corn starch capsule/d). Results: Participants maintained their dietary intake throughout the study, except for vitamin E intake that increased after supplementation with baru almonds (P = 0.013). The daily addition of 20 g of baru almonds to the usual diet did not change the volunteers’ body composition neither the oxidation status (P < 0.05). Compared to placebo, supplementation of baru almonds reduced serum total cholesterol (-8.1 ± 2.4%, p = 0.007), LDL-c (-9.4 ± 2.4%, p = 0.006) and non-HDL-c (- 8.1 ± 3.0%, p = 0.013. Conclusions: Diet supplementation of mildly hypercholesterolemic subjects with baru almonds improved serum lipid parameters, so that this food might be included in diets for reducing the cardiovascular disease risk.
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spelling Naves, Maria Margareth Velosohttp://lattes.cnpq.br/6563181057140270Silva, Mara ReisCominetti, CristianeRogero, Marcelo MacedoHorst, Maria AderuzaNaves, Maria Margareth Velosohttp://lattes.cnpq.br/2585621740520216Bento, Ana Paula Nunes2014-12-30T20:16:50Z2014-03-21BENTO, Ana Paula Nunes. Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos. 2014. 97 f. Dissertação (Mestrado em Nutrição e Saúde) - Universidade Federal de Goiás, Goiânia, 2014.http://repositorio.bc.ufg.br/tede/handle/tede/3854ark:/38995/0013000007xmwObjective: To evaluate the effect of baru almonds supplementation on lipid profile and oxidation state of mildly hypercholesterolemic subjects. Material and Methods: A randomized, controlled and crossover trial was performed with 20 mildly hypercholesterolemic subjects (total cholesterol mean (± SEM) = 5.8 ± 0.2 mmol/L, aged 21–57, and mean body mass index = 23.0 ± 0.5 kg/m2). The assay had 2 periods of 6 wks each and a 4-wk washout period between the treatments. Subjects were randomly allocated in alternated periods receiving the following treatments per period: supplementation with 20 g/d of baru almonds or placebo (1 corn starch capsule/d). Results: Participants maintained their dietary intake throughout the study, except for vitamin E intake that increased after supplementation with baru almonds (P = 0.013). The daily addition of 20 g of baru almonds to the usual diet did not change the volunteers’ body composition neither the oxidation status (P < 0.05). Compared to placebo, supplementation of baru almonds reduced serum total cholesterol (-8.1 ± 2.4%, p = 0.007), LDL-c (-9.4 ± 2.4%, p = 0.006) and non-HDL-c (- 8.1 ± 3.0%, p = 0.013. Conclusions: Diet supplementation of mildly hypercholesterolemic subjects with baru almonds improved serum lipid parameters, so that this food might be included in diets for reducing the cardiovascular disease risk.Objetivo: Avaliar o efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos. Material e métodos: Foi realizado ensaio clínico randomizado, controlado, crossover com 20 indivíduos moderadamente hipercolesterolêmicos (colesterol total 227,3 ± 7,7 mg/dL), com idade variando entre 21 e 57 anos e IMC médio de 23,0 ± 0,5 kg/m2. O ensaio foi composto por duas fases de seis semanas, separadas por um período washout de quatro semanas. Os indivíduos foram randomizados para receber dois tratamentos em fases alternadas definidas por sorteio: 20 g/dia de amêndoa de baru ou placebo (uma cápsula/dia de amido de milho). Avaliação do consumo alimentar, antropometria e exames bioquímicos foram realizadas no início e final de cada fase. Resultados: Os indivíduos mantiveram a ingestão alimentar durante todo o estudo, com exceção da ingestão de vitamina E, que aumentou após a suplementação com a amêndoa de baru (p = 0,013). A adição de 20 g de amêndoa de baru na alimentação habitual dos participantes não alterou a composição corporal e nem o estado oxidativo (p < 0,05). Entretanto, comparado ao tratamento com o placebo, o consumo da amêndoa de baru reduziu as concentrações séricas de colesterol total (- 8.1 ± 2.4%, p = 0.007), de LDL-c (-9.4 ± 2.4%, p = 0.006) e de não-HDL-c (-8.1 ± 3.0%, p = 0.013). Conclusão: A incorporação de amêndoa de baru na dieta de indivíduos com hipercolesterolemia moderada melhorou o perfil lipídico. Sendo assim, a amêndoa de baru pode ser incluída em planos alimentares que visem a redução do risco de doenças cardiovasculares.Submitted by Erika Demachki (erikademachki@gmail.com) on 2014-12-30T20:16:30Z No. of bitstreams: 2 Dissertação - Ana Paula Nunes Bento - 2014.pdf: 7070326 bytes, checksum: 46e239eb41e1e61fb65fd2057c1a9ec6 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)Approved for entry into archive by Erika Demachki (erikademachki@gmail.com) on 2014-12-30T20:16:50Z (GMT) No. of bitstreams: 2 Dissertação - Ana Paula Nunes Bento - 2014.pdf: 7070326 bytes, checksum: 46e239eb41e1e61fb65fd2057c1a9ec6 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)Made available in DSpace on 2014-12-30T20:16:50Z (GMT). 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dc.title.por.fl_str_mv Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos
dc.title.alternative.eng.fl_str_mv Effect of baru almond intake in lipid profile and oxidative state of mildly hipercholesterolemic subjects
title Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos
spellingShingle Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos
Bento, Ana Paula Nunes
Nozes
Dislipidemias
Estresse oxidativo
Doenças cardiovasculares
Nuts
Dyslipidemias
Oxidative stress
Cardiovascular diseases
CIENCIAS DA SAUDE::NUTRICAO
title_short Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos
title_full Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos
title_fullStr Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos
title_full_unstemmed Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos
title_sort Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos
author Bento, Ana Paula Nunes
author_facet Bento, Ana Paula Nunes
author_role author
dc.contributor.advisor1.fl_str_mv Naves, Maria Margareth Veloso
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/6563181057140270
dc.contributor.advisor-co1.fl_str_mv Silva, Mara Reis
dc.contributor.advisor-co2.fl_str_mv Cominetti, Cristiane
dc.contributor.referee1.fl_str_mv Rogero, Marcelo Macedo
dc.contributor.referee2.fl_str_mv Horst, Maria Aderuza
dc.contributor.referee3.fl_str_mv Naves, Maria Margareth Veloso
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/2585621740520216
dc.contributor.author.fl_str_mv Bento, Ana Paula Nunes
contributor_str_mv Naves, Maria Margareth Veloso
Silva, Mara Reis
Cominetti, Cristiane
Rogero, Marcelo Macedo
Horst, Maria Aderuza
Naves, Maria Margareth Veloso
dc.subject.por.fl_str_mv Nozes
Dislipidemias
Estresse oxidativo
Doenças cardiovasculares
topic Nozes
Dislipidemias
Estresse oxidativo
Doenças cardiovasculares
Nuts
Dyslipidemias
Oxidative stress
Cardiovascular diseases
CIENCIAS DA SAUDE::NUTRICAO
dc.subject.eng.fl_str_mv Nuts
Dyslipidemias
Oxidative stress
Cardiovascular diseases
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE::NUTRICAO
description Objective: To evaluate the effect of baru almonds supplementation on lipid profile and oxidation state of mildly hypercholesterolemic subjects. Material and Methods: A randomized, controlled and crossover trial was performed with 20 mildly hypercholesterolemic subjects (total cholesterol mean (± SEM) = 5.8 ± 0.2 mmol/L, aged 21–57, and mean body mass index = 23.0 ± 0.5 kg/m2). The assay had 2 periods of 6 wks each and a 4-wk washout period between the treatments. Subjects were randomly allocated in alternated periods receiving the following treatments per period: supplementation with 20 g/d of baru almonds or placebo (1 corn starch capsule/d). Results: Participants maintained their dietary intake throughout the study, except for vitamin E intake that increased after supplementation with baru almonds (P = 0.013). The daily addition of 20 g of baru almonds to the usual diet did not change the volunteers’ body composition neither the oxidation status (P < 0.05). Compared to placebo, supplementation of baru almonds reduced serum total cholesterol (-8.1 ± 2.4%, p = 0.007), LDL-c (-9.4 ± 2.4%, p = 0.006) and non-HDL-c (- 8.1 ± 3.0%, p = 0.013. Conclusions: Diet supplementation of mildly hypercholesterolemic subjects with baru almonds improved serum lipid parameters, so that this food might be included in diets for reducing the cardiovascular disease risk.
publishDate 2014
dc.date.accessioned.fl_str_mv 2014-12-30T20:16:50Z
dc.date.issued.fl_str_mv 2014-03-21
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dc.identifier.citation.fl_str_mv BENTO, Ana Paula Nunes. Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos. 2014. 97 f. Dissertação (Mestrado em Nutrição e Saúde) - Universidade Federal de Goiás, Goiânia, 2014.
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identifier_str_mv BENTO, Ana Paula Nunes. Efeito do consumo da amêndoa de baru sobre o perfil lipídico e o estado oxidativo de indivíduos moderadamente hipercolesterolêmicos. 2014. 97 f. Dissertação (Mestrado em Nutrição e Saúde) - Universidade Federal de Goiás, Goiânia, 2014.
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repository.name.fl_str_mv Repositório Institucional da UFG - Universidade Federal de Goiás (UFG)
repository.mail.fl_str_mv tasesdissertacoes.bc@ufg.br
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