Perfil epidemiologico das neoplasias do colo uterino (in situ e invasoras) diagnosticadas na cidade de goiânia: análise de 17 anos (1988-2004)

• Autor(a) principal: ALMEIDA, Fábio Marques de
• Data de Publicação: 2010
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Repositório Institucional da UFG
• dARK ID: ark:/38995/00130000096mp
• Texto Completo: http://repositorio.bc.ufg.br/tede/handle/tde/1731
• topic: cancer do colo uterino; epidemiologia; frequencia; extensão; incidencia; goiania; goias; cancer of the cervix; epidemiology; frequency; extension; incidence; london; groove; CNPQ::CIENCIAS DA SAUDE

Determine the epidemiological profile of in situ and invasive neoplasias of the uterus cervix in Goiânia during the period from 1988 to 2004. Methodology: The cases were identified in the Population Base Register of Cancer database of Goiânia. The studied variables were: age, histological type, extension of the disease and mortality. Analysis was done by central tendency in which the incidence rates were calculated by age, extension of the disease using Census population data and the standard population of Segi; for the mortality analysis the data were extracted from Mortality Information System. Results: We identified 4446 cases of in situ and invasive neoplasias of the uterus from the period of 1988 to 2004. Histopathology was used in 91,9% of the cases; average age was 40 years old for the in situ neoplasias and 52 years for the invasive ones (DP ± 13 and 14 years old, respectively). There were 2213 (58,28%) in situ cases, 1603 invasives (41,8%) and, in 633 cases (14,2%), it was not possible to verify their extension. The annual rate of percentage change (AAPC) for the in situ incidence was 13.08% (IC 95% 9.75 16.50; p<0.0000) per year and1.27% (IC95% -1.74 4.37; p<0.3862) for the invasive cases. The standard mortality rate was 12.2 and 8.2 per 100,000 in 1988 and 2004 respectively, with an AAPC of -3.02 (IC95% -5,36 -0,62; p<0,0172). Squamous cell carcinoma was found to be the predominant histologic type. A reduction of the Adenocarcinoma incidence in situ was not found nor was found a significant change of the Adenocarcinoma invasive; the squamous invasive cancer did present a considerable reduction of 2,85 per year. Conclusion: It was observed that the most frequent invasive tumors were the squamous cell carcinomas and Adenocarcinomas. Data did not demonstrate a rise in the diagnosis of invasive neoplasia, although there occurred an increase of diagnoses of in situ neoplasias. Mortality has demonstrated a tendency of reduction, suggesting that improvements of the tracking programs have changed the incidence or uterine cancer, though it has not yet accomplished all its objectives. Keywords: cervical cancer, uterus, epidemiology, frequency, extension, incidence, Goiânia, Brazil.