Avaliação cognitiva de pacientes com glaucoma e sua comparação com indivíduos com demência de Alzheimer

Detalhes bibliográficos
Autor(a) principal: Maurano, Stephanie Toledo Piza
Data de Publicação: 2014
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFG
dARK ID: ark:/38995/001300000f850
Texto Completo: http://repositorio.bc.ufg.br/tede/handle/tede/5652
Resumo: This study aimed to evaluate the cognitive performance of patients with glaucoma and compare it to people with Alzheimer's disease (AD). Glaucoma patients, AD and control group (healthy elderly) were assessed using the MMSE (Mini Mental State Examination) and the subtests verbal fluency, word list memory, delayed recall of the word list, word list recognition test Boston naming test and construction praxis from CERAD (Consortium to Establish a Registry for Alzheimer's Disease). The results of each test were compared between the groups. One hundred and twelve patients were evaluated, 50 healthy elderly with a mean age of 71.2 ± 5.2 years; 41 patients with glaucoma (72.2 ± 4.4 years) and 21 patients with AD (79.0 ± 7.6 years). AD patients had, on average, advanced disease. Noted a reduction in the cognitive assessment tests in all evaluated, both for patients with glaucoma, and for those with AD compared with controls (p <0.001 for all). When the results from patients with glaucoma and AD were paired, it was noted that the AD patients had lower cognitive function (p <0.001), except for the tests CERAD Boston (p = 0.1) and praxis (p = 0.6). Glaucoma patients, however, presented results of cognitive tests similar to those described for patients with mild AD, including lower values for MMSE (21.9 ± 3.7), Boston (10.6 ± 2.6) and praxis (5.9 ± 2.3).
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spelling Silva, Leopoldo Magacho dos Santoshttp://lattes.cnpq.br/8749557033319190Silva, Leopoldo Magacho dos SantosIsaac, David Leonardo CruvinelLima, Francisco Eduardo Lopes deFerreira, Sandra de Fátima BarbosaCarneiro, Haroldo Macielhttp://lattes.cnpq.br/6165082396423128Maurano, Stephanie Toledo Piza2016-06-06T15:26:33Z2014-11-11MAURANO, S. T. P. Avaliação cognitiva de pacientes com glaucoma e sua comparação com indivíduos com demência de Alzheimer. 2014. 49 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2014.http://repositorio.bc.ufg.br/tede/handle/tede/5652ark:/38995/001300000f850This study aimed to evaluate the cognitive performance of patients with glaucoma and compare it to people with Alzheimer's disease (AD). Glaucoma patients, AD and control group (healthy elderly) were assessed using the MMSE (Mini Mental State Examination) and the subtests verbal fluency, word list memory, delayed recall of the word list, word list recognition test Boston naming test and construction praxis from CERAD (Consortium to Establish a Registry for Alzheimer's Disease). The results of each test were compared between the groups. One hundred and twelve patients were evaluated, 50 healthy elderly with a mean age of 71.2 ± 5.2 years; 41 patients with glaucoma (72.2 ± 4.4 years) and 21 patients with AD (79.0 ± 7.6 years). AD patients had, on average, advanced disease. Noted a reduction in the cognitive assessment tests in all evaluated, both for patients with glaucoma, and for those with AD compared with controls (p <0.001 for all). When the results from patients with glaucoma and AD were paired, it was noted that the AD patients had lower cognitive function (p <0.001), except for the tests CERAD Boston (p = 0.1) and praxis (p = 0.6). Glaucoma patients, however, presented results of cognitive tests similar to those described for patients with mild AD, including lower values for MMSE (21.9 ± 3.7), Boston (10.6 ± 2.6) and praxis (5.9 ± 2.3).Este estudo teve como objetivo avaliar o desempenho cognitivo de pacientes com glaucoma e compará-lo a uma população diagnosticada com demência de Alzheimer (DA) e seus controles. Pacientes com glaucoma, DA e grupo controle (idosos saudáveis) foram avaliados através do MEEM (Mini Exame do Estado Mental) e os subtestes fluência verbal, memória de lista de palavras, evocação tardia da lista de palavras, reconhecimento da lista de palavras, teste de nomeação de Boston e praxia construtiva do CERAD (Consortium to Establish a Registry for Alzheimer’s Disease). Os resultados de cada teste foram comparados entre os grupos. Foram avaliados 112 pacientes, sendo 50 idosos saudáveis com idade média de 71,2 ±5,2 anos; 41 pacientes com glaucoma (72,2 ± 4,4 anos) e 21 pacientes com DA (79,0 ±7,6 anos). Os pacientes com DA apresentaram, em média, doença avançada. Notou-se redução da avaliação cognitiva em todos os testes avaliados tanto para os pacientes com glaucoma quanto para aqueles com DA quando comparados com os controles (p<0,001 para todos). Ao se parear os pacientes com glaucoma e DA, notou-se que os últimos apresentaram função cognitiva inferior (p<0,001), exceto para os subtestes do CERAD Boston (p=0,1) e Praxia (p=0,6). Os pacientes com glaucoma, entretanto, apresentaram resultados dos testes cognitivos semelhantes àqueles descritos para pacientes com DA leve, inclusive com valores inferiores para MEEM (21,9 ± 3,7), Boston (10,6 ± 2,6) e Praxia (5,9 ± 2,3).Submitted by Cássia Santos (cassia.bcufg@gmail.com) on 2016-06-06T12:10:03Z No. of bitstreams: 2 Dissertação - Stephanie Toledo Piza Maurano - 2014.pdf: 609176 bytes, checksum: f12745cac385e6d01adbcfcb69724fc0 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2016-06-06T15:26:33Z (GMT) No. of bitstreams: 2 Dissertação - Stephanie Toledo Piza Maurano - 2014.pdf: 609176 bytes, checksum: f12745cac385e6d01adbcfcb69724fc0 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)Made available in DSpace on 2016-06-06T15:26:33Z (GMT). No. of bitstreams: 2 Dissertação - Stephanie Toledo Piza Maurano - 2014.pdf: 609176 bytes, checksum: f12745cac385e6d01adbcfcb69724fc0 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) Previous issue date: 2014-11-11application/pdfporUniversidade Federal de GoiásPrograma de Pós-graduação em Ciências da Saúde (FM)UFGBrasilFaculdade de Medicina - FM (RG)http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessCogniçãoGlaucomaDemência de AlzheimerCognitionGlaucomaAlzheimer’s diseaseCIENCIAS DA SAUDEAvaliação cognitiva de pacientes com glaucoma e sua comparação com indivíduos com demência de AlzheimerCognitive assessment with glaucoma’s patient and it’s comparison with individuals with Alzheimer's diseaseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis-100686431261774531060060060015457724759504863388765449414823306929reponame:Repositório Institucional da UFGinstname:Universidade Federal de Goiás (UFG)instacron:UFGLICENSElicense.txtlicense.txttext/plain; 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dc.title.por.fl_str_mv Avaliação cognitiva de pacientes com glaucoma e sua comparação com indivíduos com demência de Alzheimer
dc.title.alternative.eng.fl_str_mv Cognitive assessment with glaucoma’s patient and it’s comparison with individuals with Alzheimer's disease
title Avaliação cognitiva de pacientes com glaucoma e sua comparação com indivíduos com demência de Alzheimer
spellingShingle Avaliação cognitiva de pacientes com glaucoma e sua comparação com indivíduos com demência de Alzheimer
Maurano, Stephanie Toledo Piza
Cognição
Glaucoma
Demência de Alzheimer
Cognition
Glaucoma
Alzheimer’s disease
CIENCIAS DA SAUDE
title_short Avaliação cognitiva de pacientes com glaucoma e sua comparação com indivíduos com demência de Alzheimer
title_full Avaliação cognitiva de pacientes com glaucoma e sua comparação com indivíduos com demência de Alzheimer
title_fullStr Avaliação cognitiva de pacientes com glaucoma e sua comparação com indivíduos com demência de Alzheimer
title_full_unstemmed Avaliação cognitiva de pacientes com glaucoma e sua comparação com indivíduos com demência de Alzheimer
title_sort Avaliação cognitiva de pacientes com glaucoma e sua comparação com indivíduos com demência de Alzheimer
author Maurano, Stephanie Toledo Piza
author_facet Maurano, Stephanie Toledo Piza
author_role author
dc.contributor.advisor1.fl_str_mv Silva, Leopoldo Magacho dos Santos
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/8749557033319190
dc.contributor.referee1.fl_str_mv Silva, Leopoldo Magacho dos Santos
dc.contributor.referee2.fl_str_mv Isaac, David Leonardo Cruvinel
dc.contributor.referee3.fl_str_mv Lima, Francisco Eduardo Lopes de
dc.contributor.referee4.fl_str_mv Ferreira, Sandra de Fátima Barbosa
dc.contributor.referee5.fl_str_mv Carneiro, Haroldo Maciel
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/6165082396423128
dc.contributor.author.fl_str_mv Maurano, Stephanie Toledo Piza
contributor_str_mv Silva, Leopoldo Magacho dos Santos
Silva, Leopoldo Magacho dos Santos
Isaac, David Leonardo Cruvinel
Lima, Francisco Eduardo Lopes de
Ferreira, Sandra de Fátima Barbosa
Carneiro, Haroldo Maciel
dc.subject.por.fl_str_mv Cognição
Glaucoma
Demência de Alzheimer
topic Cognição
Glaucoma
Demência de Alzheimer
Cognition
Glaucoma
Alzheimer’s disease
CIENCIAS DA SAUDE
dc.subject.eng.fl_str_mv Cognition
Glaucoma
Alzheimer’s disease
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE
description This study aimed to evaluate the cognitive performance of patients with glaucoma and compare it to people with Alzheimer's disease (AD). Glaucoma patients, AD and control group (healthy elderly) were assessed using the MMSE (Mini Mental State Examination) and the subtests verbal fluency, word list memory, delayed recall of the word list, word list recognition test Boston naming test and construction praxis from CERAD (Consortium to Establish a Registry for Alzheimer's Disease). The results of each test were compared between the groups. One hundred and twelve patients were evaluated, 50 healthy elderly with a mean age of 71.2 ± 5.2 years; 41 patients with glaucoma (72.2 ± 4.4 years) and 21 patients with AD (79.0 ± 7.6 years). AD patients had, on average, advanced disease. Noted a reduction in the cognitive assessment tests in all evaluated, both for patients with glaucoma, and for those with AD compared with controls (p <0.001 for all). When the results from patients with glaucoma and AD were paired, it was noted that the AD patients had lower cognitive function (p <0.001), except for the tests CERAD Boston (p = 0.1) and praxis (p = 0.6). Glaucoma patients, however, presented results of cognitive tests similar to those described for patients with mild AD, including lower values for MMSE (21.9 ± 3.7), Boston (10.6 ± 2.6) and praxis (5.9 ± 2.3).
publishDate 2014
dc.date.issued.fl_str_mv 2014-11-11
dc.date.accessioned.fl_str_mv 2016-06-06T15:26:33Z
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dc.identifier.citation.fl_str_mv MAURANO, S. T. P. Avaliação cognitiva de pacientes com glaucoma e sua comparação com indivíduos com demência de Alzheimer. 2014. 49 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2014.
dc.identifier.uri.fl_str_mv http://repositorio.bc.ufg.br/tede/handle/tede/5652
dc.identifier.dark.fl_str_mv ark:/38995/001300000f850
identifier_str_mv MAURANO, S. T. P. Avaliação cognitiva de pacientes com glaucoma e sua comparação com indivíduos com demência de Alzheimer. 2014. 49 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2014.
ark:/38995/001300000f850
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