Perspectivas em pesquisas sobre o gênero Campomanesia; estudos fitoquímicos e investigação de atividades biológicas em Campomanesia guazumifolia (Cambess) O. Berg - Myrtaceae

• Autor(a) principal: Steckelberg, Rosa Maria de Brito
• Data de Publicação: 2022
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Repositório Institucional da UFG
• dARK ID: ark:/38995/0013000005b2w
• Texto Completo: http://repositorio.bc.ufg.br/tede/handle/tede/13281
• topic: Bibliometria; Cienciometria; Atividade larvicida; Atividade antimicrobiana; Bibliometrics; Scientometrics; Larvicidal activity; Antimicrobial activity; CIENCIAS DA SAUDE::FARMACIA::ANALISE E CONTROLE E MEDICAMENTOS

Introduction: One of the challenges of public policies to encourage the use of herbal medicines is the inclusion of more native species, such as those of the Campomanesia genus, among the options for taking advantage of Brazilian biodiversity. Identifying research trends on the genus and species may arouse the interest of researchers so that more native species, such as Campomanesia guazumifolia (C.g) can be integrated into health systems where exotic species predominate. Objectives: To evaluate the scientific production of the genus Campomanesia and main species, especially C.g, in which the leaves of cultivated specimens were the object of pharmacognostic studies, phytochemical profile, essential oil characterization, antioxidant potential and biological activities. Methodology: Scientific production on the genus and species was evaluated using scientometric tools using the Web of Science database and the VOSviewer application. The experimental part consisted of traditional pharmacognostic studies; the essential oil was characterized by means of gas chromatography coupled to a mass spectrometer (GC-MS); the antioxidant potential was evaluated by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging method; larvicidal activity by mortality of Aedes aegypti L3 larvae and the antimicrobial activity was tested by a broth microdilution test. Results and discussion: Brazil leads research on gender and most of them occurred after the implementation of herbal medicine policies. C.g was the species with the highest proportional volume of publications in the last 5 years. The species presented flavonoids, tannins, saponins and triterpenes in its composition. The major compound of the essential oil (EO) was β-caryophyllene. The species showed good antioxidant (leaf extract and powder), larvicidal (EO) and antimicrobial activity, mainly against Candida sp and Micrococcus luteus strains. Conclusions: C. guazumifolia is a promising species for further research on biological activities and other studies that can support the traditional use and also as a phytomedicine.