Ultrassonografia da articulação femorotibiopatelar de ovinos com sinovite experimental

Detalhes bibliográficos
Autor(a) principal: Souza, Michel Felipe Soares
Data de Publicação: 2019
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFG
Texto Completo: http://repositorio.bc.ufg.br/tede/handle/tede/10674
Resumo: The ovine stifle joint is complex and multiple bone and soft tissue elements comprise its anatomy. It is used as an experimental model for human stifle joint disease studies. Articular ultrasonography is an important diagnostic technique for articular diseases. However, there is a gap in the literature regarding ultrasound assessment of the ovine stifle joint as an experimental model. Thus, the purpose of this study was to describe sonographic changes of the ovine stifle joint undergone experimentally induced synovitis. Twelve ovine received intra-articular infusion of E. coli lipopolysaccharide in the right stifle joint to induce synovitis. Injected stifles were assessed by ultrasound at baseline and 12, 24, 48, 72 and 120 hours after intra-articular injection of lipopolysaccharide. Nine ultrasound positions were used to assess the stifle joint: suprapatelar area; lateral area of the femorotibial compartment; infrapatelar space; medial area of the femorotibial compartment; lateral femoropatelar compartment; medial femoropatelar compartment; craniolateral area; sheath of the origin of the extensor muscle tendons; and medial supracondilar recess. Stifle joint was evaluated for volume changes in the synovial fluid, thickness of the synovial membrane and cellularity. Intra-articular lipopolysaccharide injection yielded echographic changes in seven out of nine scanning positions at the ovine stifle joint. Changes were observed when the medial femorotibial compartment was evaluated in 11 animals (91.7%), in the craniolateral region, in 10 animals (83,34%), in the tendinous recess, in 11 animals (91.7%), and in the infrapatellar space, lateral and medial aspects of the femoropatellar compartments and medial supracondilar recess in all animals (100%). It was not observed alterations within the suprapatellar region and the lateral femorotibial compartment. Stifle joint ultrasound assessment was efficient for detection of intra-articular changes following infiltration with lipopolysaccharide in the ovine experimental model. The most observed signs were increase of the synovial fluid volume and thickening of the synovial membrane, 12, 24 and 48 hours after infiltration.
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spelling Silva, Marco Augusto Machadohttp://lattes.cnpq.br/2134206254307043Borges, Naida Cristinahttp://lattes.cnpq.br/9181279951885005Silva, Marco Augusto MachadoBorges, Naida CristinaSilva, Marcelo Seixo de Brito eCardoso, Júlio RoqueteSouza, Luiz Augusto dehttp://lattes.cnpq.br/1091659461301677Souza, Michel Felipe Soares2020-09-14T10:53:11Z2020-09-14T10:53:11Z2019-01-17SOUZA, M. F. S. Ultrassonografia da articulação femorotibiopatelar de ovinos com sinovite experimental. 2019. 54 f. Dissertação (Mestrado em Ciência Animal) - Universidade Federal de Goiás, Goiânia, 2019.http://repositorio.bc.ufg.br/tede/handle/tede/10674ark:/38995/001300000b4vdThe ovine stifle joint is complex and multiple bone and soft tissue elements comprise its anatomy. It is used as an experimental model for human stifle joint disease studies. Articular ultrasonography is an important diagnostic technique for articular diseases. However, there is a gap in the literature regarding ultrasound assessment of the ovine stifle joint as an experimental model. Thus, the purpose of this study was to describe sonographic changes of the ovine stifle joint undergone experimentally induced synovitis. Twelve ovine received intra-articular infusion of E. coli lipopolysaccharide in the right stifle joint to induce synovitis. Injected stifles were assessed by ultrasound at baseline and 12, 24, 48, 72 and 120 hours after intra-articular injection of lipopolysaccharide. Nine ultrasound positions were used to assess the stifle joint: suprapatelar area; lateral area of the femorotibial compartment; infrapatelar space; medial area of the femorotibial compartment; lateral femoropatelar compartment; medial femoropatelar compartment; craniolateral area; sheath of the origin of the extensor muscle tendons; and medial supracondilar recess. Stifle joint was evaluated for volume changes in the synovial fluid, thickness of the synovial membrane and cellularity. Intra-articular lipopolysaccharide injection yielded echographic changes in seven out of nine scanning positions at the ovine stifle joint. Changes were observed when the medial femorotibial compartment was evaluated in 11 animals (91.7%), in the craniolateral region, in 10 animals (83,34%), in the tendinous recess, in 11 animals (91.7%), and in the infrapatellar space, lateral and medial aspects of the femoropatellar compartments and medial supracondilar recess in all animals (100%). It was not observed alterations within the suprapatellar region and the lateral femorotibial compartment. Stifle joint ultrasound assessment was efficient for detection of intra-articular changes following infiltration with lipopolysaccharide in the ovine experimental model. The most observed signs were increase of the synovial fluid volume and thickening of the synovial membrane, 12, 24 and 48 hours after infiltration.A articulação femorotibiopatelar do ovino é complexa por possuir elementos ósseos e de tecidos moles, sendo frequentemente utilizada como modelo experimental no estudo de doenças dessa articulação em pacientes humanos. A ultrassonografia articular constitui importante técnica de diagnóstico de doenças articulares, entretanto, poucos estudos descrevem seu uso para avaliação de lesões da articulação do joelho em ovinos como modelo experimental. O objetivo desse estudo foi descrever os aspectos ultrassonográficos da articulação femorotibiopatelar de ovinos com sinovite experimental. Em doze ovinos foi induzida sinovite mediante aplicação intra-articular de lipopolissacarídeo de parede de E. coli, na articulação femorotibiopatelar direita, e avaliados por ultrassonografia às 12, 24, 48, 72 e 120 horas após a indução. Uma avaliação antes da indução foi realizada, para meios de controle. Foram utilizados nove acessos ecográficos para avaliação: região suprapatelar; compartimento femorotibial lateral; espaço infrapatelar; compartimento femorotibial medial; porção lateral do compartimento femoropatelar; porção medial do compartimento femoropatelar; região craniolateral; recesso tendinoso; e recesso supracondilar medial. Avaliou-se alterações no volume do fluido sinovial com expansão da cavidade articular, pregueamento da membrana sinovial e celularidade. A aplicação intra-articular de lipopolissacarídeo de E. coli resultou, em sete de nove posições, em sinais ecográficos de sinovite. Foram observadas alterações intra ou periarticulares ao exame do compartimento femorotibial medial, em 11 animais (91,7%), na região craniolateral, em 10 animais (83,34%), no recesso tendinoso, em 11 animais (91,7%); e no espaço infrapatelar, porções lateral e medial do compartimento femoropatelar e recesso supracondilar medial em todos os animais (100%). Na região suprapatelar e no compartimento femorotibial lateral, não foram encontradas alterações ecográficas. A avaliação ultrassonográfica foi eficaz na identificação de alterações sugestivas à sinovite na articulação femorotibiopatelar de ovinos induzida por lipopolissacarídeo. Os sinais de sinovite mais observados foram aumento de volume do fluido sinovial e pregueamento da membrana sinovial, predominantemente vistos às 12, 24 e 48 horas após infiltração.Submitted by Marlene Santos (marlene.bc.ufg@gmail.com) on 2020-09-13T14:27:56Z No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Dissertação - Michel Felipe Soares Souza - 2019.pdf: 2627729 bytes, checksum: 89f1d5fe059be4e0127e52ed6883c97e (MD5)Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2020-09-14T10:53:11Z (GMT) No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Dissertação - Michel Felipe Soares Souza - 2019.pdf: 2627729 bytes, checksum: 89f1d5fe059be4e0127e52ed6883c97e (MD5)Made available in DSpace on 2020-09-14T10:53:11Z (GMT). No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Dissertação - Michel Felipe Soares Souza - 2019.pdf: 2627729 bytes, checksum: 89f1d5fe059be4e0127e52ed6883c97e (MD5) Previous issue date: 2019-01-17OutroporUniversidade Federal de GoiásPrograma de Pós-graduação em Ciência Animal (EVZ)UFGBrasilEscola de Veterinária e Zootecnia - EVZ (RG)Attribution-NonCommercial-NoDerivs 3.0 Brazilhttp://creativecommons.org/licenses/by-nc-nd/3.0/br/info:eu-repo/semantics/openAccessArtriteClaudicaçãoJoelhoUltrassonografiaArthritisKneeLamenessUltrasonographyCIENCIAS AGRARIAS::MEDICINA VETERINARIA::CLINICA E CIRURGIA ANIMAL::CLINICA VETERINARIAUltrassonografia da articulação femorotibiopatelar de ovinos com sinovite experimentalUltrasound assessment of sheep stifle joint undergone lipopolysaccharide-induced synovitisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis1850050050050062415reponame:Repositório Institucional da UFGinstname:Universidade Federal de Goiás (UFG)instacron:UFGLICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://repositorio.bc.ufg.br/tede/bitstreams/e906c9cf-5507-4f21-ad24-84604ebb6754/download8a4605be74aa9ea9d79846c1fba20a33MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8811http://repositorio.bc.ufg.br/tede/bitstreams/696976cb-7b54-4d56-b8ab-6360b2b3ad9f/downloade39d27027a6cc9cb039ad269a5db8e34MD52ORIGINALDissertação - Michel Felipe Soares Souza - 2019.pdfDissertação - Michel Felipe Soares Souza - 2019.pdfapplication/pdf2627729http://repositorio.bc.ufg.br/tede/bitstreams/468badaf-497f-4e2a-a062-cdc4423e9365/download89f1d5fe059be4e0127e52ed6883c97eMD53tede/106742020-09-14 07:53:12.38http://creativecommons.org/licenses/by-nc-nd/3.0/br/Attribution-NonCommercial-NoDerivs 3.0 Brazilopen.accessoai:repositorio.bc.ufg.br:tede/10674http://repositorio.bc.ufg.br/tedeRepositório InstitucionalPUBhttp://repositorio.bc.ufg.br/oai/requesttasesdissertacoes.bc@ufg.bropendoar:2020-09-14T10:53:12Repositório Institucional da UFG - Universidade Federal de Goiás (UFG)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
dc.title.pt_BR.fl_str_mv Ultrassonografia da articulação femorotibiopatelar de ovinos com sinovite experimental
dc.title.alternative.eng.fl_str_mv Ultrasound assessment of sheep stifle joint undergone lipopolysaccharide-induced synovitis
title Ultrassonografia da articulação femorotibiopatelar de ovinos com sinovite experimental
spellingShingle Ultrassonografia da articulação femorotibiopatelar de ovinos com sinovite experimental
Souza, Michel Felipe Soares
Artrite
Claudicação
Joelho
Ultrassonografia
Arthritis
Knee
Lameness
Ultrasonography
CIENCIAS AGRARIAS::MEDICINA VETERINARIA::CLINICA E CIRURGIA ANIMAL::CLINICA VETERINARIA
title_short Ultrassonografia da articulação femorotibiopatelar de ovinos com sinovite experimental
title_full Ultrassonografia da articulação femorotibiopatelar de ovinos com sinovite experimental
title_fullStr Ultrassonografia da articulação femorotibiopatelar de ovinos com sinovite experimental
title_full_unstemmed Ultrassonografia da articulação femorotibiopatelar de ovinos com sinovite experimental
title_sort Ultrassonografia da articulação femorotibiopatelar de ovinos com sinovite experimental
author Souza, Michel Felipe Soares
author_facet Souza, Michel Felipe Soares
author_role author
dc.contributor.advisor1.fl_str_mv Silva, Marco Augusto Machado
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/2134206254307043
dc.contributor.advisor-co1.fl_str_mv Borges, Naida Cristina
dc.contributor.advisor-co1Lattes.fl_str_mv http://lattes.cnpq.br/9181279951885005
dc.contributor.referee1.fl_str_mv Silva, Marco Augusto Machado
dc.contributor.referee2.fl_str_mv Borges, Naida Cristina
dc.contributor.referee3.fl_str_mv Silva, Marcelo Seixo de Brito e
dc.contributor.referee4.fl_str_mv Cardoso, Júlio Roquete
dc.contributor.referee5.fl_str_mv Souza, Luiz Augusto de
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/1091659461301677
dc.contributor.author.fl_str_mv Souza, Michel Felipe Soares
contributor_str_mv Silva, Marco Augusto Machado
Borges, Naida Cristina
Silva, Marco Augusto Machado
Borges, Naida Cristina
Silva, Marcelo Seixo de Brito e
Cardoso, Júlio Roquete
Souza, Luiz Augusto de
dc.subject.por.fl_str_mv Artrite
Claudicação
Joelho
Ultrassonografia
topic Artrite
Claudicação
Joelho
Ultrassonografia
Arthritis
Knee
Lameness
Ultrasonography
CIENCIAS AGRARIAS::MEDICINA VETERINARIA::CLINICA E CIRURGIA ANIMAL::CLINICA VETERINARIA
dc.subject.eng.fl_str_mv Arthritis
Knee
Lameness
Ultrasonography
dc.subject.cnpq.fl_str_mv CIENCIAS AGRARIAS::MEDICINA VETERINARIA::CLINICA E CIRURGIA ANIMAL::CLINICA VETERINARIA
description The ovine stifle joint is complex and multiple bone and soft tissue elements comprise its anatomy. It is used as an experimental model for human stifle joint disease studies. Articular ultrasonography is an important diagnostic technique for articular diseases. However, there is a gap in the literature regarding ultrasound assessment of the ovine stifle joint as an experimental model. Thus, the purpose of this study was to describe sonographic changes of the ovine stifle joint undergone experimentally induced synovitis. Twelve ovine received intra-articular infusion of E. coli lipopolysaccharide in the right stifle joint to induce synovitis. Injected stifles were assessed by ultrasound at baseline and 12, 24, 48, 72 and 120 hours after intra-articular injection of lipopolysaccharide. Nine ultrasound positions were used to assess the stifle joint: suprapatelar area; lateral area of the femorotibial compartment; infrapatelar space; medial area of the femorotibial compartment; lateral femoropatelar compartment; medial femoropatelar compartment; craniolateral area; sheath of the origin of the extensor muscle tendons; and medial supracondilar recess. Stifle joint was evaluated for volume changes in the synovial fluid, thickness of the synovial membrane and cellularity. Intra-articular lipopolysaccharide injection yielded echographic changes in seven out of nine scanning positions at the ovine stifle joint. Changes were observed when the medial femorotibial compartment was evaluated in 11 animals (91.7%), in the craniolateral region, in 10 animals (83,34%), in the tendinous recess, in 11 animals (91.7%), and in the infrapatellar space, lateral and medial aspects of the femoropatellar compartments and medial supracondilar recess in all animals (100%). It was not observed alterations within the suprapatellar region and the lateral femorotibial compartment. Stifle joint ultrasound assessment was efficient for detection of intra-articular changes following infiltration with lipopolysaccharide in the ovine experimental model. The most observed signs were increase of the synovial fluid volume and thickening of the synovial membrane, 12, 24 and 48 hours after infiltration.
publishDate 2019
dc.date.issued.fl_str_mv 2019-01-17
dc.date.accessioned.fl_str_mv 2020-09-14T10:53:11Z
dc.date.available.fl_str_mv 2020-09-14T10:53:11Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.citation.fl_str_mv SOUZA, M. F. S. Ultrassonografia da articulação femorotibiopatelar de ovinos com sinovite experimental. 2019. 54 f. Dissertação (Mestrado em Ciência Animal) - Universidade Federal de Goiás, Goiânia, 2019.
dc.identifier.uri.fl_str_mv http://repositorio.bc.ufg.br/tede/handle/tede/10674
dc.identifier.dark.fl_str_mv ark:/38995/001300000b4vd
identifier_str_mv SOUZA, M. F. S. Ultrassonografia da articulação femorotibiopatelar de ovinos com sinovite experimental. 2019. 54 f. Dissertação (Mestrado em Ciência Animal) - Universidade Federal de Goiás, Goiânia, 2019.
ark:/38995/001300000b4vd
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rights_invalid_str_mv Attribution-NonCommercial-NoDerivs 3.0 Brazil
http://creativecommons.org/licenses/by-nc-nd/3.0/br/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Universidade Federal de Goiás
dc.publisher.program.fl_str_mv Programa de Pós-graduação em Ciência Animal (EVZ)
dc.publisher.initials.fl_str_mv UFG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Escola de Veterinária e Zootecnia - EVZ (RG)
publisher.none.fl_str_mv Universidade Federal de Goiás
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