Aspectos clínico-epidemiológicos e tratamento da tripanosomose bovina por trypanosoma vivax no estado de Goiás

Detalhes bibliográficos
Autor(a) principal: Bastos, Thiago Souza Azeredo
Data de Publicação: 2019
Tipo de documento: Tese
Idioma: por
Título da fonte: Repositório Institucional da UFG
dARK ID: ark:/38995/001300000d542
Texto Completo: http://repositorio.bc.ufg.br/tede/handle/tede/11059
Resumo: This study reports the first case of bovine trypanosomiasis caused by Trypanosoma vivax in Goiás, Brazil, as well as other cases that occurred within a period of 24 months, demonstrating epidemiological aspects such as needle sharing and commercialization of infected cows influencing the spread of this disease. Furthermore, it was observed that T. vivax was able to infect and develop the disease in calves when they were inoculated by the intradermal, subcutaneous, intramuscular or intravenous route. The presence of Anaplasma marginale latent in calves with trypanosomiasis interfer directly in the percentage of mortality of the animals. Finally, with regard to efficacy, only animals that received isometamidium were able to remain without new parasitaemia after 180 days of study. Treatment with diminazene allowed new parasitemia when reinfected 50 days after treatment and, finally, imidocarb was not effective in the treatment of bovine trypanosomosis. This is the first study that describes the presence of T. vivax, as well as its epidemiology in the State of Goiás, evaluated the infection capacity of this parasite by different pathways, clinical signs, and diagnostic methods and also evaluated the efficacy of the treatment with imidocarb, diminazene and isometamidium in cattle experimentally infected with T. vivax in Brazil.
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spelling Lopes, Welber Daniel Zanettihttp://lattes.cnpq.br/4480577038117234Linhares, Guido Fontgalland Coelhohttp://lattes.cnpq.br/6261928164195145Lopes, Welber Daniel ZanettiFelippelli, GustavoKrawczak, Felipe da SilvaFerreira, Lorena LopesSilveira Neto, Osvaldo José dahttp://lattes.cnpq.br/2996614490112819Bastos, Thiago Souza Azeredo2021-01-22T15:12:42Z2021-01-22T15:12:42Z2019-03-01BASTOS, T. S. A. Aspectos clínico-epidemiológicos e tratamento da tripanosomose bovina por trypanosoma vivax no estado de Goiás. 2019. 85 f. Tese (Doutorado em Ciência Animal) - Universidade Federal de Goiás, Goiânia, 2019.http://repositorio.bc.ufg.br/tede/handle/tede/11059ark:/38995/001300000d542This study reports the first case of bovine trypanosomiasis caused by Trypanosoma vivax in Goiás, Brazil, as well as other cases that occurred within a period of 24 months, demonstrating epidemiological aspects such as needle sharing and commercialization of infected cows influencing the spread of this disease. Furthermore, it was observed that T. vivax was able to infect and develop the disease in calves when they were inoculated by the intradermal, subcutaneous, intramuscular or intravenous route. The presence of Anaplasma marginale latent in calves with trypanosomiasis interfer directly in the percentage of mortality of the animals. Finally, with regard to efficacy, only animals that received isometamidium were able to remain without new parasitaemia after 180 days of study. Treatment with diminazene allowed new parasitemia when reinfected 50 days after treatment and, finally, imidocarb was not effective in the treatment of bovine trypanosomosis. This is the first study that describes the presence of T. vivax, as well as its epidemiology in the State of Goiás, evaluated the infection capacity of this parasite by different pathways, clinical signs, and diagnostic methods and also evaluated the efficacy of the treatment with imidocarb, diminazene and isometamidium in cattle experimentally infected with T. vivax in Brazil.Este estudo relata o primeiro caso de Tripanosomose bovina causada por Trypanosoma vivax no Estado de Goiás, bem como outros casos que ocorreram dentro de um período de 24 meses, demonstrando aspectos epidemiológicos, como o compartilhamento de agulhas e a comercialização de vacas infectadas, que influenciaram na dispersão da doença. Ainda, observou-se que T. vivax foi capaz de infectar e desenvolver a doença em bezerros, independente se inoculados pela via intradérmica, subcutânea, intramuscular ou endovenosa. A presença de Anaplasma marginale latente nos bezerros com tripanosomose interferiu diretamente no percentual de mortalidade dos animais. Por fim, com relação à eficácia, apenas animais que receberam isometamidium foram capaz de permanecer sem nova parasitemia durante os 180 dias de estudo. Animais que receberam diminazene apresentou nova parasitemia quando reinfectado 50 dias após tratamento e, por ultimo, imidocarb não foi eficaz no tratamento da tripanosomose bovina. Este é o primeiro trabalho que descreve a presença de T. vivax, bem como sua epidemiologia no Estado de Goiás, avaliou a capacidade de infecção deste parasito por diferentes vias, os sinais clínicos, métodos de diagnóstico e, também, avaliou a eficácia do tratamento com imidocarb, diminazene e isometamidium em bovinos experimentalmente infectados com T. vivax no Brasil.Submitted by Marlene Santos (marlene.bc.ufg@gmail.com) on 2021-01-22T14:52:25Z No. of bitstreams: 2 license_rdf: 805 bytes, checksum: 4460e5956bc1d1639be9ae6146a50347 (MD5) Tese - Thiago Souza Azeredo Bastos - 2019.pdf: 9843238 bytes, checksum: d8ba20cf7c290f29ada96f4335f7aca1 (MD5)Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2021-01-22T15:12:42Z (GMT) No. of bitstreams: 2 license_rdf: 805 bytes, checksum: 4460e5956bc1d1639be9ae6146a50347 (MD5) Tese - Thiago Souza Azeredo Bastos - 2019.pdf: 9843238 bytes, checksum: d8ba20cf7c290f29ada96f4335f7aca1 (MD5)Made available in DSpace on 2021-01-22T15:12:42Z (GMT). No. of bitstreams: 2 license_rdf: 805 bytes, checksum: 4460e5956bc1d1639be9ae6146a50347 (MD5) Tese - Thiago Souza Azeredo Bastos - 2019.pdf: 9843238 bytes, checksum: d8ba20cf7c290f29ada96f4335f7aca1 (MD5) Previous issue date: 2019-03-01OutroporUniversidade Federal de GoiásPrograma de Pós-graduação em Ciência Animal (EVZ)UFGBrasilEscola de Veterinária e Zootecnia - EVZ (RG)Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessBrasilBovinosInfecçãoTripanossomoseBrazilBovineInfectionTrypanosomaCIENCIAS AGRARIAS::ZOOTECNIA::NUTRICAO E ALIMENTACAO ANIMALAspectos clínico-epidemiológicos e tratamento da tripanosomose bovina por trypanosoma vivax no estado de GoiásClinical and epidemiological aspects and treatment of bovine trypanosomiasis by trypanosoma vivax in the state of Goiásinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesis18500500500500613145reponame:Repositório Institucional da UFGinstname:Universidade Federal de Goiás (UFG)instacron:UFGLICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://repositorio.bc.ufg.br/tede/bitstreams/690a449f-e801-45c5-b285-e5f687da019e/download8a4605be74aa9ea9d79846c1fba20a33MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805http://repositorio.bc.ufg.br/tede/bitstreams/8f54fd0f-cbe9-424c-8f45-ae7890a0f079/download4460e5956bc1d1639be9ae6146a50347MD52ORIGINALTese - Thiago Souza Azeredo Bastos - 2019.pdfTese - Thiago Souza Azeredo Bastos - 2019.pdfapplication/pdf9843238http://repositorio.bc.ufg.br/tede/bitstreams/bd222949-13b9-499d-a86e-c501d6cbb3b4/downloadd8ba20cf7c290f29ada96f4335f7aca1MD53tede/110592021-01-22 12:12:43.074http://creativecommons.org/licenses/by-nc-nd/4.0/Attribution-NonCommercial-NoDerivatives 4.0 Internationalopen.accessoai:repositorio.bc.ufg.br:tede/11059http://repositorio.bc.ufg.br/tedeRepositório InstitucionalPUBhttp://repositorio.bc.ufg.br/oai/requesttasesdissertacoes.bc@ufg.bropendoar:2021-01-22T15:12:43Repositório Institucional da UFG - Universidade Federal de Goiás (UFG)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
dc.title.pt_BR.fl_str_mv Aspectos clínico-epidemiológicos e tratamento da tripanosomose bovina por trypanosoma vivax no estado de Goiás
dc.title.alternative.eng.fl_str_mv Clinical and epidemiological aspects and treatment of bovine trypanosomiasis by trypanosoma vivax in the state of Goiás
title Aspectos clínico-epidemiológicos e tratamento da tripanosomose bovina por trypanosoma vivax no estado de Goiás
spellingShingle Aspectos clínico-epidemiológicos e tratamento da tripanosomose bovina por trypanosoma vivax no estado de Goiás
Bastos, Thiago Souza Azeredo
Brasil
Bovinos
Infecção
Tripanossomose
Brazil
Bovine
Infection
Trypanosoma
CIENCIAS AGRARIAS::ZOOTECNIA::NUTRICAO E ALIMENTACAO ANIMAL
title_short Aspectos clínico-epidemiológicos e tratamento da tripanosomose bovina por trypanosoma vivax no estado de Goiás
title_full Aspectos clínico-epidemiológicos e tratamento da tripanosomose bovina por trypanosoma vivax no estado de Goiás
title_fullStr Aspectos clínico-epidemiológicos e tratamento da tripanosomose bovina por trypanosoma vivax no estado de Goiás
title_full_unstemmed Aspectos clínico-epidemiológicos e tratamento da tripanosomose bovina por trypanosoma vivax no estado de Goiás
title_sort Aspectos clínico-epidemiológicos e tratamento da tripanosomose bovina por trypanosoma vivax no estado de Goiás
author Bastos, Thiago Souza Azeredo
author_facet Bastos, Thiago Souza Azeredo
author_role author
dc.contributor.advisor1.fl_str_mv Lopes, Welber Daniel Zanetti
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/4480577038117234
dc.contributor.advisor-co1.fl_str_mv Linhares, Guido Fontgalland Coelho
dc.contributor.advisor-co1Lattes.fl_str_mv http://lattes.cnpq.br/6261928164195145
dc.contributor.referee1.fl_str_mv Lopes, Welber Daniel Zanetti
dc.contributor.referee2.fl_str_mv Felippelli, Gustavo
dc.contributor.referee3.fl_str_mv Krawczak, Felipe da Silva
dc.contributor.referee4.fl_str_mv Ferreira, Lorena Lopes
dc.contributor.referee5.fl_str_mv Silveira Neto, Osvaldo José da
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/2996614490112819
dc.contributor.author.fl_str_mv Bastos, Thiago Souza Azeredo
contributor_str_mv Lopes, Welber Daniel Zanetti
Linhares, Guido Fontgalland Coelho
Lopes, Welber Daniel Zanetti
Felippelli, Gustavo
Krawczak, Felipe da Silva
Ferreira, Lorena Lopes
Silveira Neto, Osvaldo José da
dc.subject.por.fl_str_mv Brasil
Bovinos
Infecção
Tripanossomose
topic Brasil
Bovinos
Infecção
Tripanossomose
Brazil
Bovine
Infection
Trypanosoma
CIENCIAS AGRARIAS::ZOOTECNIA::NUTRICAO E ALIMENTACAO ANIMAL
dc.subject.eng.fl_str_mv Brazil
Bovine
Infection
Trypanosoma
dc.subject.cnpq.fl_str_mv CIENCIAS AGRARIAS::ZOOTECNIA::NUTRICAO E ALIMENTACAO ANIMAL
description This study reports the first case of bovine trypanosomiasis caused by Trypanosoma vivax in Goiás, Brazil, as well as other cases that occurred within a period of 24 months, demonstrating epidemiological aspects such as needle sharing and commercialization of infected cows influencing the spread of this disease. Furthermore, it was observed that T. vivax was able to infect and develop the disease in calves when they were inoculated by the intradermal, subcutaneous, intramuscular or intravenous route. The presence of Anaplasma marginale latent in calves with trypanosomiasis interfer directly in the percentage of mortality of the animals. Finally, with regard to efficacy, only animals that received isometamidium were able to remain without new parasitaemia after 180 days of study. Treatment with diminazene allowed new parasitemia when reinfected 50 days after treatment and, finally, imidocarb was not effective in the treatment of bovine trypanosomosis. This is the first study that describes the presence of T. vivax, as well as its epidemiology in the State of Goiás, evaluated the infection capacity of this parasite by different pathways, clinical signs, and diagnostic methods and also evaluated the efficacy of the treatment with imidocarb, diminazene and isometamidium in cattle experimentally infected with T. vivax in Brazil.
publishDate 2019
dc.date.issued.fl_str_mv 2019-03-01
dc.date.accessioned.fl_str_mv 2021-01-22T15:12:42Z
dc.date.available.fl_str_mv 2021-01-22T15:12:42Z
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dc.identifier.citation.fl_str_mv BASTOS, T. S. A. Aspectos clínico-epidemiológicos e tratamento da tripanosomose bovina por trypanosoma vivax no estado de Goiás. 2019. 85 f. Tese (Doutorado em Ciência Animal) - Universidade Federal de Goiás, Goiânia, 2019.
dc.identifier.uri.fl_str_mv http://repositorio.bc.ufg.br/tede/handle/tede/11059
dc.identifier.dark.fl_str_mv ark:/38995/001300000d542
identifier_str_mv BASTOS, T. S. A. Aspectos clínico-epidemiológicos e tratamento da tripanosomose bovina por trypanosoma vivax no estado de Goiás. 2019. 85 f. Tese (Doutorado em Ciência Animal) - Universidade Federal de Goiás, Goiânia, 2019.
ark:/38995/001300000d542
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http://creativecommons.org/licenses/by-nc-nd/4.0/
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dc.publisher.none.fl_str_mv Universidade Federal de Goiás
dc.publisher.program.fl_str_mv Programa de Pós-graduação em Ciência Animal (EVZ)
dc.publisher.initials.fl_str_mv UFG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Escola de Veterinária e Zootecnia - EVZ (RG)
publisher.none.fl_str_mv Universidade Federal de Goiás
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