Estudo clínico e epidemiológico das apresentações iniciais de pacientes com transtorno afetivo bipolar–tipo I e II
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFG |
dARK ID: | ark:/38995/001300000bvbd |
Texto Completo: | http://repositorio.bc.ufg.br/tede/handle/tde/2913 |
Resumo: | There are several studies on the differential diagnosis of Bipolar Disorder (BD), however, further investigation with an emphasis on clinical phenotypes that inaugurate the disease is needed. The aims of this study are to identify the psychiatric disorders most frequently diagnosed before the definitive diagnosis of BD, the time until the correct diagnosis and compare BD I and II for the variables studied. We studied 259 patients with current diagnosis of BD according to the DSM- IV-TR, evaluated by the same psychiatrist. Early psychiatric signs and symptoms were identified through an interview with the patient and family members and were considered suggestive of an initial diagnosis that was coded according to the same diagnostic criteria. The authors analyzed data on patients' age at prodromes suggestive of initial psychiatric diagnosis and time delay to the actual diagnosis of BD. Comparisons were made between sex, schooling and type of BD. The mean age of patients was 41.6 years, with a predominance of adults (19-60 years), women (67.6%), as well as type II BD (68.3%). Patients were on average 24.6 years of age at initial diagnosis, 41.6 years in the diagnosis of BD and the mean time delay between these was 16.9 years. The most common initial diagnoses were depressive disorders (41.3%), anxiety (12.7%), ADHD (8.1%), disorders related to substance abuse (7.7%), somatoform disorders (6 9%), and psychosis (5.4%). BD can be considered a “great imitator” in modern psychiatry, since initial phenotypes can mimic other disorders. BD diagnosis is very delayed in Brazil. |
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Caixeta, Leonardo Ferreirahttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4735432Y9http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4460249H3Chaves, Moysés de Paula Rodrigues2014-08-21T12:48:09Z2013-09-30CHAVES, Moysés de Paula Rodrigues. Estudo clínico e epidemiológico das apresentações iniciais de pacientes com transtorno afetivo bipolar–tipo I e II. 2013. 49 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2013.http://repositorio.bc.ufg.br/tede/handle/tde/2913ark:/38995/001300000bvbdThere are several studies on the differential diagnosis of Bipolar Disorder (BD), however, further investigation with an emphasis on clinical phenotypes that inaugurate the disease is needed. The aims of this study are to identify the psychiatric disorders most frequently diagnosed before the definitive diagnosis of BD, the time until the correct diagnosis and compare BD I and II for the variables studied. We studied 259 patients with current diagnosis of BD according to the DSM- IV-TR, evaluated by the same psychiatrist. Early psychiatric signs and symptoms were identified through an interview with the patient and family members and were considered suggestive of an initial diagnosis that was coded according to the same diagnostic criteria. The authors analyzed data on patients' age at prodromes suggestive of initial psychiatric diagnosis and time delay to the actual diagnosis of BD. Comparisons were made between sex, schooling and type of BD. The mean age of patients was 41.6 years, with a predominance of adults (19-60 years), women (67.6%), as well as type II BD (68.3%). Patients were on average 24.6 years of age at initial diagnosis, 41.6 years in the diagnosis of BD and the mean time delay between these was 16.9 years. The most common initial diagnoses were depressive disorders (41.3%), anxiety (12.7%), ADHD (8.1%), disorders related to substance abuse (7.7%), somatoform disorders (6 9%), and psychosis (5.4%). BD can be considered a “great imitator” in modern psychiatry, since initial phenotypes can mimic other disorders. BD diagnosis is very delayed in Brazil.Há diversos estudos sobre o diagnóstico diferencial do Transtorno Bipolar (TB), entretanto, investigações com ênfase nos fenótipos clínicos que inauguram a doença são escassos. Os objetivos deste estudo consistem em identificar as doenças psiquiátricas mais frequentemente diagnosticadas antes do diagnóstico definitivo de TB, assim como o intervalo de tempo até o mesmo; e comparar o pacientes com TB I e II quanto aos diagnósticos iniciais, escolaridade, sexo e faixa etária. Para tanto, estudamos 259 pacientes com diagnóstico atual de TB segundo os critérios do DSM-IV-TR, realizado por um mesmo psiquiatra. Através de entrevistas com o paciente e familiares, identificou-se retrospectivamente os sinais e sintomas precoces considerados sugestivos do primeiro diagnóstico psiquiátrico, segundo os mesmos critérios. Dados relativos à idade dos pacientes no diagnóstico inicial e tempo até o diagnóstico atual de TB foram analisados e comparações foram feitas entre sexo, escolaridade, faixa etária e tipo de TB. A média de idade encontrada foi de 41,6 anos, com predominância de adultos (19-60 anos), do gênero feminino (67,6%), com TB II(68,3%). Os pacientes tinham em média 24,6 anos de idade no diagnóstico inicial, 41,6 anos no diagnóstico de TB e o tempo médio de atraso diagnóstico foi de 16,9 anos. Os diagnósticos iniciais mais frequentemente encontrados foram: transtornos depressivos (41,3%), ansiosos (12,7%), TDAH (8,1%), transtornos relacionados ao abuso de substâncias psicoativas (7,7%), transtornos somatoformes (6,9%) e psicóticos (5,4%). O T pode ser considerado um “grande imitador” moderno da Psiquiatria, posto que fenótipos iniciais podem mimetizar outros transtornos. Há um atraso significativo no diagnóstico do TBno Brasil.Submitted by Luciana Ferreira (lucgeral@gmail.com) on 2014-08-21T12:48:09Z No. of bitstreams: 2 license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) DISSERTACAO MESTRADO MOYSES PRONTA (1) (1).pdf: 679547 bytes, checksum: cf4dd53c812b868e1a8d7ceb72f62419 (MD5)Made available in DSpace on 2014-08-21T12:48:09Z (GMT). No. of bitstreams: 2 license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) DISSERTACAO MESTRADO MOYSES PRONTA (1) (1).pdf: 679547 bytes, checksum: cf4dd53c812b868e1a8d7ceb72f62419 (MD5) Previous issue date: 2013-09-30application/pdfhttp://repositorio.bc.ufg.br/tede/retrieve/6428/DISSERTACAO%20MESTRADO%20MOYSES%20PRONTA%20%281%29%20%281%29.pdf.jpgporUniversidade Federal de GoiásPrograma de Pós-graduação em Ciências da Saúde (FM)UFGBrasilFaculdade de Medicina - FM (RG)Akiskal, H.S.,Bourgeois, M.L., Angst, J.,Post, R., Moller, H., Hirschfeld, R., 2000. Reevaluatingtheprevalence ofand diagnosticcomposition within thebroadclinical spectrum ofbipolardisorders.Journal ofaffectivedisorders 59Suppl 1, S5-S30. Angst, J., 1998. Theemergingepidemiologyofhypomaniaand bipolar IIdisorder.Journal ofaffectivedisorders 50, 143-151. Angst, J., Gamma, A., Lewinsohn, P., 2002. Theevolvingepidemiologyof bipolardisorder. 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Comorbidityofadult attention-deficit hyperactivitydisorderand bipolardisorder: prevalenceandclinical correlates. European archives ofpsychiatryandclinical neuroscience258, 385-393. Tavormina, G., 2011.Aresomatisationsymptoms important evidenceforanearlydiagnosis ofbipolarspectrum mood disorders? Psychiatria Danubina23Suppl 1, S13-14. Thompson, K.N., Conus, P.O., Ward, J.L., Phillips, L.J., Koutsogiannis, J., Leicester, S., McGorry, P.D., 2003. The initial prodrome to bipolar affective disorder: prospective case studies.Journal ofaffectivedisorders 77, 79-85. Thornicroft, G., Rose, D., Kassam, A., Sartorius, N., 2007.Stigma: ignorance, prejudiceor discrimination? TheBritish journal ofpsychiatry: thejournal ofmental science190, 192193. Wingo, A.P., Ghaemi, S.N., 2007. Asystematicreview ofrates and diagnosticvalidityof comorbid adult attention-deficit/hyperactivitydisorderand bipolardisorder. 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dc.title.por.fl_str_mv |
Estudo clínico e epidemiológico das apresentações iniciais de pacientes com transtorno afetivo bipolar–tipo I e II |
dc.title.alternative.por.fl_str_mv |
Clinical and epidemiological study of the early presentations of patients with bipolar disoder - types I and II |
title |
Estudo clínico e epidemiológico das apresentações iniciais de pacientes com transtorno afetivo bipolar–tipo I e II |
spellingShingle |
Estudo clínico e epidemiológico das apresentações iniciais de pacientes com transtorno afetivo bipolar–tipo I e II Chaves, Moysés de Paula Rodrigues Transtorno bipolar Erros diagnósticos Atraso diagnóstico Idade de início Bipolar disorder Misdiagnosis Diagnostic delay Age at onset CIENCIAS DA SAUDE |
title_short |
Estudo clínico e epidemiológico das apresentações iniciais de pacientes com transtorno afetivo bipolar–tipo I e II |
title_full |
Estudo clínico e epidemiológico das apresentações iniciais de pacientes com transtorno afetivo bipolar–tipo I e II |
title_fullStr |
Estudo clínico e epidemiológico das apresentações iniciais de pacientes com transtorno afetivo bipolar–tipo I e II |
title_full_unstemmed |
Estudo clínico e epidemiológico das apresentações iniciais de pacientes com transtorno afetivo bipolar–tipo I e II |
title_sort |
Estudo clínico e epidemiológico das apresentações iniciais de pacientes com transtorno afetivo bipolar–tipo I e II |
author |
Chaves, Moysés de Paula Rodrigues |
author_facet |
Chaves, Moysés de Paula Rodrigues |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Caixeta, Leonardo Ferreira |
dc.contributor.advisor1Lattes.fl_str_mv |
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4735432Y9 |
dc.contributor.authorLattes.fl_str_mv |
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4460249H3 |
dc.contributor.author.fl_str_mv |
Chaves, Moysés de Paula Rodrigues |
contributor_str_mv |
Caixeta, Leonardo Ferreira |
dc.subject.por.fl_str_mv |
Transtorno bipolar Erros diagnósticos Atraso diagnóstico Idade de início |
topic |
Transtorno bipolar Erros diagnósticos Atraso diagnóstico Idade de início Bipolar disorder Misdiagnosis Diagnostic delay Age at onset CIENCIAS DA SAUDE |
dc.subject.eng.fl_str_mv |
Bipolar disorder Misdiagnosis Diagnostic delay Age at onset |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE |
description |
There are several studies on the differential diagnosis of Bipolar Disorder (BD), however, further investigation with an emphasis on clinical phenotypes that inaugurate the disease is needed. The aims of this study are to identify the psychiatric disorders most frequently diagnosed before the definitive diagnosis of BD, the time until the correct diagnosis and compare BD I and II for the variables studied. We studied 259 patients with current diagnosis of BD according to the DSM- IV-TR, evaluated by the same psychiatrist. Early psychiatric signs and symptoms were identified through an interview with the patient and family members and were considered suggestive of an initial diagnosis that was coded according to the same diagnostic criteria. The authors analyzed data on patients' age at prodromes suggestive of initial psychiatric diagnosis and time delay to the actual diagnosis of BD. Comparisons were made between sex, schooling and type of BD. The mean age of patients was 41.6 years, with a predominance of adults (19-60 years), women (67.6%), as well as type II BD (68.3%). Patients were on average 24.6 years of age at initial diagnosis, 41.6 years in the diagnosis of BD and the mean time delay between these was 16.9 years. The most common initial diagnoses were depressive disorders (41.3%), anxiety (12.7%), ADHD (8.1%), disorders related to substance abuse (7.7%), somatoform disorders (6 9%), and psychosis (5.4%). BD can be considered a “great imitator” in modern psychiatry, since initial phenotypes can mimic other disorders. BD diagnosis is very delayed in Brazil. |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013-09-30 |
dc.date.accessioned.fl_str_mv |
2014-08-21T12:48:09Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
CHAVES, Moysés de Paula Rodrigues. Estudo clínico e epidemiológico das apresentações iniciais de pacientes com transtorno afetivo bipolar–tipo I e II. 2013. 49 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2013. |
dc.identifier.uri.fl_str_mv |
http://repositorio.bc.ufg.br/tede/handle/tde/2913 |
dc.identifier.dark.fl_str_mv |
ark:/38995/001300000bvbd |
identifier_str_mv |
CHAVES, Moysés de Paula Rodrigues. Estudo clínico e epidemiológico das apresentações iniciais de pacientes com transtorno afetivo bipolar–tipo I e II. 2013. 49 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2013. ark:/38995/001300000bvbd |
url |
http://repositorio.bc.ufg.br/tede/handle/tde/2913 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.program.fl_str_mv |
-1006864312617745310 |
dc.relation.confidence.fl_str_mv |
600 600 600 |
dc.relation.department.fl_str_mv |
1545772475950486338 |
dc.relation.cnpq.fl_str_mv |
8765449414823306929 |
dc.relation.references.por.fl_str_mv |
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National trends in theoutpatient diagnosis andtreatment of bipolardisorderin youth. Archives of general psychiatry64, 1032-1039. Pacchiarotti, I., Di Marzo, S., Colom, F.,Sanchez-Moreno,J., Vieta, E., 2009.Bipolar disorderprecededbysubstanceabuse: adifferent phenotypewith not so poor outcome? The world journal ofbiological psychiatry: theofficial journal oftheWorld Federation of Societies ofBiological Psychiatry10, 209-216. Paris,J., Gunderson,J.,Weinberg, I., 2007. Theinterfacebetween borderlinepersonality disorderand bipolarspectrum disorders. Comprehensivepsychiatry48, 145-154. Perlis, R.H., 2005. Misdiagnosis ofbipolardisorder. TheAmerican journal ofmanaged care 11,S271-274. Perlis, R.H., Miyahara,S., Marangell, L.B.,Wisniewski, S.R., Ostacher,M., DelBello, M.P., Bowden, C.L., Sachs, G.S., Nierenberg, A.A., Investigators, S.-B., 2004. Long-term implications ofearlyonset in bipolardisorder: datafrom thefirst 1000 participants in the systematictreatment enhancement program forbipolardisorder(STEP-BD).Biological psychiatry55, 875-881. Rubinsztein,J.S., Michael, A., Paykel, E.S.,Sahakian,B.J., 2000. Cognitiveimpairment in remission in bipolaraffectivedisorder.Psychological medicine30, 1025-1036. jelstad, D.V., Malt, U.F., Holte, A., 2010.Symptoms and signs oftheinitial prodromeof bipolardisorder: asystematicreview.Journal ofaffective disorders 126, 1-13. Tamam, L., Karakus, G., Ozpoyraz, N., 2008. Comorbidityofadult attention-deficit hyperactivitydisorderand bipolardisorder: prevalenceandclinical correlates. European archives ofpsychiatryandclinical neuroscience258, 385-393. Tavormina, G., 2011.Aresomatisationsymptoms important evidenceforanearlydiagnosis ofbipolarspectrum mood disorders? Psychiatria Danubina23Suppl 1, S13-14. Thompson, K.N., Conus, P.O., Ward, J.L., Phillips, L.J., Koutsogiannis, J., Leicester, S., McGorry, P.D., 2003. The initial prodrome to bipolar affective disorder: prospective case studies.Journal ofaffectivedisorders 77, 79-85. Thornicroft, G., Rose, D., Kassam, A., Sartorius, N., 2007.Stigma: ignorance, prejudiceor discrimination? TheBritish journal ofpsychiatry: thejournal ofmental science190, 192193. Wingo, A.P., Ghaemi, S.N., 2007. Asystematicreview ofrates and diagnosticvalidityof comorbid adult attention-deficit/hyperactivitydisorderand bipolardisorder. TheJournal of clinical psychiatry68, 1776-1784. |
dc.rights.driver.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess |
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http://creativecommons.org/licenses/by-nc-nd/4.0/ |
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openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.publisher.program.fl_str_mv |
Programa de Pós-graduação em Ciências da Saúde (FM) |
dc.publisher.initials.fl_str_mv |
UFG |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Faculdade de Medicina - FM (RG) |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
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