Infecção experimental por Trypanosoma vivax em bovinos da raça curraleiro pé-duro

• Autor(a) principal: Mendonça, Débora Ribeiro de
• Data de Publicação: 2019
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Repositório Institucional da UFG
• Texto Completo: http://repositorio.bc.ufg.br/tede/handle/tede/12319
• topic: Hemoparasito; Modelo experimenta; Resistência genética; Tolerância; Tripanosomose; Experimental model; Genetic resistance; Hemoparasite; Tolerance; Trypanosomiasis; CIENCIAS AGRARIAS::MEDICINA VETERINARIA::PATOLOGIA ANIMAL

In the experimental Trypanosoma vivax infection in Curraleiro Pé-Duro cattle, six healthy male cattle with a minimum age of eight to 12 months and an average body weight of 98 to 165 kg were used. The experiment was divided into three phases: adaptation (10 days), inoculation and post-inoculation (74 days) in order to evaluate physical, hematological, biochemical and parasitological parameters. The results of the physical evaluations indicated hypothermia in the initial and final phase of the evaluations and hyperthermia on the 22nd day after inoculation. There was bradycardia in the first 15 days and 45 days after inoculation, while bradypnea and hypomotility were detected throughout the evaluations. In erythrogram there was a reduction in red blood cells, hemoglobin, globular volume, mean corpuscular hemoglobin concentration (HCCM) and platelets characterizing a normocytic and hypochromic anemia. In the leukogram, leukopenia with neutropenia was identified. The bands, eosinophils, basophils, lymphocytes and monocytes did not differ because they were within the normal range. In the analysis of blood biochemistry data, changes were discrete and punctual for the following biochemical parameters: fibrinogen, total proteins, albumin, globulin, creatine kinase, glucose, creatinine, urea, total direct and indirect bilirubin. Aspartate aminotransferase activities decreased on days 18 to 60 post-inoculation and gama glutamyltransferase activities increased between days 67 and 74 post-inoculation, however, this increase was due to only two animals. Parasitaemia, diagnosed by the Woo method and quantified by the Brener method, showed to be intense in the early stage of the disease and throughout the evaluations there was a decrease in parasitaemia peaks, leading no calf to death. The cattle after experimental inoculation had mild and punctual symptoms and survived the acute phase of the disease, establishing signs of tolerance in relation to T. vivax.