HISTOPHATOLOGICAL STUDY IN CORNEAS OF DOGS, TREATED WITH 2-1 DISSODIC FOSPHATE OF BETAMETHASONE AND DISSODIC FOSPHATED/ACETATE OF DEXAMETHASONE, THAT HAD RECEIVED IMPLANTATION OF SWINE CORNEAS

• Autor(a) principal: Chaves, Nilo Sérgio Troncoso
• Data de Publicação: 2007
• Outros Autores: Barros, Paulo Sérgio de Moraes, Martins, Apóstolo Ferreira, Araújo, Eugênio Gonçalves de, Araújo, Larissa Franco de, Eurides, Duvaldo, Silva, Luiz Antônio Franco da
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Pesquisa Agropecuária Tropical (Online)
• Texto Completo: https://revistas.ufg.br/pat/article/view/2935
• topic: Histopatology; corticosteroids; xenotransplant; cornea; canine; swine; Histopatologia; corticosteróides; xenotransplantes; córnea; canino; suíno

Ten dogs, with no definitive breed, average weight of 10 kg, were in this research. After being examined and considered healthy they received numbers, from 11 to 20 in their collars. Each dog received implantation, in the left eye, of swine cornea, obtained at Casa de Banha Caçula, a slaughterhouse, and maintained in wet chamber for six hours at most. Before surgery, each animal received 4 mg of dissodic phosphate/acetate dexamethasone IM and, once a week one drop of dissodic phosphate betamethasone and gentamicin sulphate, four times a day, until the 28th day. when the animals were sacrificed through painless process (Thiopental sodic + succinilcolin chloride ), and the eye that had received the implantation of swine cornea was enucleated. Formaldehyde 10% was injected in the vitreous camera and after that the eye was placed in a container and the cornea was removed with sclerous ring, treated and colored with hematoxilin-eosin. The implantation and the cornea nearby areas were analysed as well as the alterations. KEY-WORDS: Histopatology; corticosteroids; xenotransplant; cornea; canine; swine.