Portuguese Resistance of gastrointestinal nematoids of goats and sheep to the antihelmintics levamisol, ivermectin and albendazole
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2023 |
| Outros Autores: | , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por eng |
| Título da fonte: | Ciência animal brasileira (Online) |
| Texto Completo: | https://revistas.ufg.br/vet/article/view/75316 |
Resumo: | The aim of this study was to determine the resistance of gastrointestinal nematodes in goats and sheep to the anthelmintic drugs levamisole, ivermectin, and albendazole in the metropolitan region of São Luís Island, Maranhão, Brazil. Fecal samples were collected from 150 animals across four different farms; two farms had goats, and the other two had sheep. The samples were then randomly divided into three to four groups of 10 animals: Group I: control, without treatment; Group II: ivermectin treatment; Group III: levamisole treatment; and Group IV: albendazole treatment. Stool samples were collected from the rectal ampulla one day before treatment and 10 days after anthelmintic treatment. Individual coproparasitological examinations were performed using the modified McMaster technique at the Animal Health Laboratory of the Federal Institute of Maranhão, Campus São Luís-Maracanã. The efficacies of the anthelmintic drugs against gastrointestinal nematodes in goats and sheep were: 14.28%, and 13.6% for ivermectin; 0% and 79.4% for levamisole; and 59.8% and 3.43% for albendazole, respectively Gastrointestinal nematodes demonstrated multiple anthelmintic resistance, as the percentage reduction in egg count was less than 95% and the lower limit of the confidence interval was less than 90%.Keywords: antiparasitic drugs; anthelmintic resistance; small ruminants |
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Portuguese Resistance of gastrointestinal nematoids of goats and sheep to the antihelmintics levamisol, ivermectin and albendazole Resistência de nematoides gastrintestinais de caprinos e ovinos aos anti-helmínticos levamisol, ivermectina e albendazol The aim of this study was to determine the resistance of gastrointestinal nematodes in goats and sheep to the anthelmintic drugs levamisole, ivermectin, and albendazole in the metropolitan region of São Luís Island, Maranhão, Brazil. Fecal samples were collected from 150 animals across four different farms; two farms had goats, and the other two had sheep. The samples were then randomly divided into three to four groups of 10 animals: Group I: control, without treatment; Group II: ivermectin treatment; Group III: levamisole treatment; and Group IV: albendazole treatment. Stool samples were collected from the rectal ampulla one day before treatment and 10 days after anthelmintic treatment. Individual coproparasitological examinations were performed using the modified McMaster technique at the Animal Health Laboratory of the Federal Institute of Maranhão, Campus São Luís-Maracanã. The efficacies of the anthelmintic drugs against gastrointestinal nematodes in goats and sheep were: 14.28%, and 13.6% for ivermectin; 0% and 79.4% for levamisole; and 59.8% and 3.43% for albendazole, respectively Gastrointestinal nematodes demonstrated multiple anthelmintic resistance, as the percentage reduction in egg count was less than 95% and the lower limit of the confidence interval was less than 90%.Keywords: antiparasitic drugs; anthelmintic resistance; small ruminantsObjetivou-se determinar a resistência de nematoides gastrintestinais aos anti-helmínticos levamisol, ivermectina e albendazol em caprinos e ovinos da região metropolitana da Ilha de São Luís, Maranhão, Brasil. Foram coletadas amostras de fezes de 150 animais de quatro propriedades diferentes, sendo 2 com caprinos e 2 com ovinos, e aleatoriamente distribuídos de três a quatro grupos de 10 animais: Grupo I: grupo controle, sem tratamento. Grupo II: tratado com anti-helmíntico à base de ivermectina, administrado oralmente na dose de 200 mcg/kg; Grupo III: tratado com anti-helmíntico à base de levamisol, administrado oralmente na dose de 7,5mg/kg e Grupo IV: tratado com anti-helmíntico à base de albendazol administrado oralmente na dose de 3mg/kg. Amostras de fezes foram colhidas da ampola retal um dia antes do tratamento e 10 dias após o tratamento anti-helmíntico. Foram feitos exames coproparasitológicos individuais, pela técnica de McMaster modificada, no Laboratório de Sanidade Animal, do Instituto Federal do Maranhão (IFMA), Campus São Luís-Maracanã. A ivermectina, na espécie caprina, mostrou eficácia de 14,28%, enquanto para ovina, 13,6 e 52,2%. Considerando o levamisol na espécie caprina, não apresentou eficácia contra os nematoides gastrintestinais, enquanto para ovinos, apresentou eficácia de 79,4%. Já o albendazol, apresentou eficácia de 59,8% para caprinos, e 3,43% para ovinos. Os nematoides gastrintestinais demonstraram resistência múltipla (RAM), visto que a percentagem de redução da contagem de ovos foi inferior a 95% e o limite inferior do intervalo de confiança menor do que 90%. Palavras-chave: antiparasitários; resistência anti-helmíntica; pequenos ruminantesUniversidade Federal de Goiás2023-05-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://revistas.ufg.br/vet/article/view/75316Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 24 (2023): Continuous publicationCiência Animal Brasileira / Brazilian Animal Science; v. 24 (2023): Publicação contínua1809-68911518-2797reponame:Ciência animal brasileira (Online)instname:Universidade Federal de Goiás (UFG)instacron:UFGporenghttps://revistas.ufg.br/vet/article/view/75316/39828https://revistas.ufg.br/vet/article/view/75316/40029https://revistas.ufg.br/vet/article/view/75316/39829https://revistas.ufg.br/vet/article/view/75316/40030Copyright (c) 2023 Ciência Animal Brasileira / Brazilian Animal Sciencehttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPinheiro Soares, Swênia ChristinaCunha Reis, ArnonPereira Castro, Rogério LeanSerejo Pires Filho, Pedro CelestinoSaraiva Martins Cabral, CelecinaOliveira Diniz Júnior, DurvalBarros Costa, Camilada Costa Pinheiro, Dara MariaAlves Pinheiro, Yasmin SuelenSilva Buna, Nayla HelenaMartins Costa Júnior, LivioRodrigues Barros Brito, Danilo2023-08-24T18:50:55Zoai:ojs.revistas.ufg.br:article/75316Revistahttps://revistas.ufg.br/vetPUBhttps://revistas.ufg.br/vet/oai||revistacab@gmail.com1809-68911518-2797opendoar:2024-05-21T19:56:36.088909Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)true |
| dc.title.none.fl_str_mv |
Portuguese Resistance of gastrointestinal nematoids of goats and sheep to the antihelmintics levamisol, ivermectin and albendazole Resistência de nematoides gastrintestinais de caprinos e ovinos aos anti-helmínticos levamisol, ivermectina e albendazol |
| title |
Portuguese Resistance of gastrointestinal nematoids of goats and sheep to the antihelmintics levamisol, ivermectin and albendazole |
| spellingShingle |
Portuguese Resistance of gastrointestinal nematoids of goats and sheep to the antihelmintics levamisol, ivermectin and albendazole Pinheiro Soares, Swênia Christina |
| title_short |
Portuguese Resistance of gastrointestinal nematoids of goats and sheep to the antihelmintics levamisol, ivermectin and albendazole |
| title_full |
Portuguese Resistance of gastrointestinal nematoids of goats and sheep to the antihelmintics levamisol, ivermectin and albendazole |
| title_fullStr |
Portuguese Resistance of gastrointestinal nematoids of goats and sheep to the antihelmintics levamisol, ivermectin and albendazole |
| title_full_unstemmed |
Portuguese Resistance of gastrointestinal nematoids of goats and sheep to the antihelmintics levamisol, ivermectin and albendazole |
| title_sort |
Portuguese Resistance of gastrointestinal nematoids of goats and sheep to the antihelmintics levamisol, ivermectin and albendazole |
| author |
Pinheiro Soares, Swênia Christina |
| author_facet |
Pinheiro Soares, Swênia Christina Cunha Reis, Arnon Pereira Castro, Rogério Lean Serejo Pires Filho, Pedro Celestino Saraiva Martins Cabral, Celecina Oliveira Diniz Júnior, Durval Barros Costa, Camila da Costa Pinheiro, Dara Maria Alves Pinheiro, Yasmin Suelen Silva Buna, Nayla Helena Martins Costa Júnior, Livio Rodrigues Barros Brito, Danilo |
| author_role |
author |
| author2 |
Cunha Reis, Arnon Pereira Castro, Rogério Lean Serejo Pires Filho, Pedro Celestino Saraiva Martins Cabral, Celecina Oliveira Diniz Júnior, Durval Barros Costa, Camila da Costa Pinheiro, Dara Maria Alves Pinheiro, Yasmin Suelen Silva Buna, Nayla Helena Martins Costa Júnior, Livio Rodrigues Barros Brito, Danilo |
| author2_role |
author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Pinheiro Soares, Swênia Christina Cunha Reis, Arnon Pereira Castro, Rogério Lean Serejo Pires Filho, Pedro Celestino Saraiva Martins Cabral, Celecina Oliveira Diniz Júnior, Durval Barros Costa, Camila da Costa Pinheiro, Dara Maria Alves Pinheiro, Yasmin Suelen Silva Buna, Nayla Helena Martins Costa Júnior, Livio Rodrigues Barros Brito, Danilo |
| description |
The aim of this study was to determine the resistance of gastrointestinal nematodes in goats and sheep to the anthelmintic drugs levamisole, ivermectin, and albendazole in the metropolitan region of São Luís Island, Maranhão, Brazil. Fecal samples were collected from 150 animals across four different farms; two farms had goats, and the other two had sheep. The samples were then randomly divided into three to four groups of 10 animals: Group I: control, without treatment; Group II: ivermectin treatment; Group III: levamisole treatment; and Group IV: albendazole treatment. Stool samples were collected from the rectal ampulla one day before treatment and 10 days after anthelmintic treatment. Individual coproparasitological examinations were performed using the modified McMaster technique at the Animal Health Laboratory of the Federal Institute of Maranhão, Campus São Luís-Maracanã. The efficacies of the anthelmintic drugs against gastrointestinal nematodes in goats and sheep were: 14.28%, and 13.6% for ivermectin; 0% and 79.4% for levamisole; and 59.8% and 3.43% for albendazole, respectively Gastrointestinal nematodes demonstrated multiple anthelmintic resistance, as the percentage reduction in egg count was less than 95% and the lower limit of the confidence interval was less than 90%.Keywords: antiparasitic drugs; anthelmintic resistance; small ruminants |
| publishDate |
2023 |
| dc.date.none.fl_str_mv |
2023-05-30 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
https://revistas.ufg.br/vet/article/view/75316 |
| url |
https://revistas.ufg.br/vet/article/view/75316 |
| dc.language.iso.fl_str_mv |
por eng |
| language |
por eng |
| dc.relation.none.fl_str_mv |
https://revistas.ufg.br/vet/article/view/75316/39828 https://revistas.ufg.br/vet/article/view/75316/40029 https://revistas.ufg.br/vet/article/view/75316/39829 https://revistas.ufg.br/vet/article/view/75316/40030 |
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Copyright (c) 2023 Ciência Animal Brasileira / Brazilian Animal Science http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
Copyright (c) 2023 Ciência Animal Brasileira / Brazilian Animal Science http://creativecommons.org/licenses/by/4.0 |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
application/pdf application/pdf |
| dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
| publisher.none.fl_str_mv |
Universidade Federal de Goiás |
| dc.source.none.fl_str_mv |
Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 24 (2023): Continuous publication Ciência Animal Brasileira / Brazilian Animal Science; v. 24 (2023): Publicação contínua 1809-6891 1518-2797 reponame:Ciência animal brasileira (Online) instname:Universidade Federal de Goiás (UFG) instacron:UFG |
| instname_str |
Universidade Federal de Goiás (UFG) |
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UFG |
| institution |
UFG |
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Ciência animal brasileira (Online) |
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Ciência animal brasileira (Online) |
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Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG) |
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||revistacab@gmail.com |
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1799874791238270976 |