IMMUNOGLOBULIN LEVELS IN Trypanosoma evansi INFECTED RATS

Detalhes bibliográficos
Autor(a) principal: Gressler, Lucas Trevisan
Data de Publicação: 2010
Outros Autores: Da Silva, Aleksandro Schafer, Otto, Mateus Anderson, Azevedo, Maria Isabel, Zanette, Régis Adriel, Monteiro, Silvia Gonzalez, Santurio, Janio Morais
Tipo de documento: Artigo
Idioma: por
Título da fonte: Ciência animal brasileira (Online)
Texto Completo: https://revistas.ufg.br/vet/article/view/5461
Resumo: This study aimed at evaluating the immunoglobulin levels in rats experimentally infected with Trypanosoma evansi. Twenty animals were inoculated with 106 trypomastigote forms and ten rats were used as control. Parasitemia was monitored by examining daily blood smears. Rats were separated into three equal groups in the fifth day PI: groups A and B were formed by rats with low and moderate parasitemia, respectively; group C was formed by non-infected rats. IgG and IgM were evaluated by ELISA test and were superior when compared to group C. The IgM levels did not differ between the infected groups. It may be concluded that the infected rats showed an immunological response against T. evansi, although this was not enough to eliminate the parasite in acute infection.KEY WORDS: IgG, IgM, Ratus norvergicus, Trypanosoma evansi.
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spelling IMMUNOGLOBULIN LEVELS IN Trypanosoma evansi INFECTED RATSNÍVEIS DE IMUNOGLOBULINAS EM RATOS INFECTADOS POR Trypanosoma evansiAnimal SanityTrypanosoma evansi. IgG. IgM. Ratus norvergicusThis study aimed at evaluating the immunoglobulin levels in rats experimentally infected with Trypanosoma evansi. Twenty animals were inoculated with 106 trypomastigote forms and ten rats were used as control. Parasitemia was monitored by examining daily blood smears. Rats were separated into three equal groups in the fifth day PI: groups A and B were formed by rats with low and moderate parasitemia, respectively; group C was formed by non-infected rats. IgG and IgM were evaluated by ELISA test and were superior when compared to group C. The IgM levels did not differ between the infected groups. It may be concluded that the infected rats showed an immunological response against T. evansi, although this was not enough to eliminate the parasite in acute infection.KEY WORDS: IgG, IgM, Ratus norvergicus, Trypanosoma evansi.Objetivou-se avaliar os níveis de imunoglobulinas presentes em ratos infectados experimentalmente por Trypanosoma evansi. Para isso, inocularam-se vinte animais com 106 tripomastigotas de T. evansi e dez ratos usados como controle. Controlou-se a parasitemia através de esfregaço sanguíneo diário, sendo que no quinto dia após a inoculação os animais foram divididos em três grupos homogêneos. Formaram-se os grupos A e B por ratos que apresentaram elevada e baixa parasitemia, respectivamente, e o grupo C por ratos sadios. Submeteram-se as amostras de soro ao teste de ELISA para quantificação de imunoglobulinas. A IgG e IgM de ratos dos grupos A e B foram superiores aos do grupo C. Já a IgM de ambos os grupos infectados não diferiu, apesar do grau de parasitemia. Portanto, os ratos infectados por T. evansi apresentaram resposta imunológica frente à infecção pelo flagelado, embora esta não seja suficiente para eliminar o protozoário na infecção aguda. PALAVRAS-CHAVES: IgG, IgM, Ratus norvergicus, Trypanosoma evansi.Objetivou-se avaliar os níveis de imunoglobulinas presentes em ratos infectados experimentalmente por Trypanosoma evansi. Para isso, inocularam-se vinte animais com 106 tripomastigotas de T. evansi e dez ratos usados como controle. Controlou-se a parasitemia através de esfregaço sanguíneo diário, sendo que no quinto dia após a inoculação os animais foram divididos em três grupos homogêneos. Formaram-se os grupos A e B por ratos que apresentaram elevada e baixa parasitemia, respectivamente, e o grupo C por ratos sadios. Submeteram-se as amostras de soro ao teste de ELISA para quantificação de imunoglobulinas. A IgG e IgM de ratos dos grupos A e B foram superiores aos do grupo C. Já a IgM de ambos os grupos infectados não diferiu, apesar do grau de parasitemia. Portanto, os ratos infectados por T. evansi apresentaram resposta imunológica frente à infecção pelo flagelado, embora esta não seja suficiente para eliminar o protozoário na infecção aguda. PALAVRAS-CHAVES: IgG, IgM, Ratus norvergicus, Trypanosoma evansi.Universidade Federal de Goiás2010-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionResearchAvaliado por paresPesquisa Cientificaapplication/pdftext/htmlhttps://revistas.ufg.br/vet/article/view/546110.5216/cab.v11i1.5461Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 11 No. 1 (2010); 201 - 204Ciência Animal Brasileira / Brazilian Animal Science; v. 11 n. 1 (2010); 201 - 2041809-68911518-2797reponame:Ciência animal brasileira (Online)instname:Universidade Federal de Goiás (UFG)instacron:UFGporhttps://revistas.ufg.br/vet/article/view/5461/6555https://revistas.ufg.br/vet/article/view/5461/8096Gressler, Lucas TrevisanDa Silva, Aleksandro SchaferOtto, Mateus AndersonAzevedo, Maria IsabelZanette, Régis AdrielMonteiro, Silvia GonzalezSanturio, Janio Moraisinfo:eu-repo/semantics/openAccess2010-04-02T01:31:57Zoai:ojs.revistas.ufg.br:article/5461Revistahttps://revistas.ufg.br/vetPUBhttps://revistas.ufg.br/vet/oai||revistacab@gmail.com1809-68911518-2797opendoar:2024-05-21T19:55:21.166650Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)true
dc.title.none.fl_str_mv IMMUNOGLOBULIN LEVELS IN Trypanosoma evansi INFECTED RATS
NÍVEIS DE IMUNOGLOBULINAS EM RATOS INFECTADOS POR Trypanosoma evansi
title IMMUNOGLOBULIN LEVELS IN Trypanosoma evansi INFECTED RATS
spellingShingle IMMUNOGLOBULIN LEVELS IN Trypanosoma evansi INFECTED RATS
Gressler, Lucas Trevisan
Animal Sanity
Trypanosoma evansi. IgG. IgM. Ratus norvergicus
title_short IMMUNOGLOBULIN LEVELS IN Trypanosoma evansi INFECTED RATS
title_full IMMUNOGLOBULIN LEVELS IN Trypanosoma evansi INFECTED RATS
title_fullStr IMMUNOGLOBULIN LEVELS IN Trypanosoma evansi INFECTED RATS
title_full_unstemmed IMMUNOGLOBULIN LEVELS IN Trypanosoma evansi INFECTED RATS
title_sort IMMUNOGLOBULIN LEVELS IN Trypanosoma evansi INFECTED RATS
author Gressler, Lucas Trevisan
author_facet Gressler, Lucas Trevisan
Da Silva, Aleksandro Schafer
Otto, Mateus Anderson
Azevedo, Maria Isabel
Zanette, Régis Adriel
Monteiro, Silvia Gonzalez
Santurio, Janio Morais
author_role author
author2 Da Silva, Aleksandro Schafer
Otto, Mateus Anderson
Azevedo, Maria Isabel
Zanette, Régis Adriel
Monteiro, Silvia Gonzalez
Santurio, Janio Morais
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gressler, Lucas Trevisan
Da Silva, Aleksandro Schafer
Otto, Mateus Anderson
Azevedo, Maria Isabel
Zanette, Régis Adriel
Monteiro, Silvia Gonzalez
Santurio, Janio Morais
dc.subject.por.fl_str_mv Animal Sanity
Trypanosoma evansi. IgG. IgM. Ratus norvergicus
topic Animal Sanity
Trypanosoma evansi. IgG. IgM. Ratus norvergicus
description This study aimed at evaluating the immunoglobulin levels in rats experimentally infected with Trypanosoma evansi. Twenty animals were inoculated with 106 trypomastigote forms and ten rats were used as control. Parasitemia was monitored by examining daily blood smears. Rats were separated into three equal groups in the fifth day PI: groups A and B were formed by rats with low and moderate parasitemia, respectively; group C was formed by non-infected rats. IgG and IgM were evaluated by ELISA test and were superior when compared to group C. The IgM levels did not differ between the infected groups. It may be concluded that the infected rats showed an immunological response against T. evansi, although this was not enough to eliminate the parasite in acute infection.KEY WORDS: IgG, IgM, Ratus norvergicus, Trypanosoma evansi.
publishDate 2010
dc.date.none.fl_str_mv 2010-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Research
Avaliado por pares
Pesquisa Cientifica
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistas.ufg.br/vet/article/view/5461
10.5216/cab.v11i1.5461
url https://revistas.ufg.br/vet/article/view/5461
identifier_str_mv 10.5216/cab.v11i1.5461
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revistas.ufg.br/vet/article/view/5461/6555
https://revistas.ufg.br/vet/article/view/5461/8096
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
text/html
dc.publisher.none.fl_str_mv Universidade Federal de Goiás
publisher.none.fl_str_mv Universidade Federal de Goiás
dc.source.none.fl_str_mv Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 11 No. 1 (2010); 201 - 204
Ciência Animal Brasileira / Brazilian Animal Science; v. 11 n. 1 (2010); 201 - 204
1809-6891
1518-2797
reponame:Ciência animal brasileira (Online)
instname:Universidade Federal de Goiás (UFG)
instacron:UFG
instname_str Universidade Federal de Goiás (UFG)
instacron_str UFG
institution UFG
reponame_str Ciência animal brasileira (Online)
collection Ciência animal brasileira (Online)
repository.name.fl_str_mv Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)
repository.mail.fl_str_mv ||revistacab@gmail.com
_version_ 1799874785558134784

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