BETAHISTINE DIHYDROCHLORIDE IN CANINE PERIPHERAL VESTIBULAR SYNDROME
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Ciência animal brasileira (Online) |
Texto Completo: | https://revistas.ufg.br/vet/article/view/1753 |
Resumo: | Vestibular disease is a common syndrome in small animals that may resulst of central or peripheral disease. The pathophysiology of peripheral vestibular syndrome is unknown, however it can be related to an abnormal dynamic of endolymphatic fluid or neuritis of the vestibular portion of the VIII cranial nerve. The recovery of neurological sings is slow and, in chronic cases, the neurological deficits can be irreversible. In veterinary medicine, thera are few medical options to treat this condition, however, in Medicine, betahistine dihydrochloride is used to treat peripheral vestibular disorders. These drug was used in four dogs with vestibular syndrome. The results showed clinical improvement in 7 to 10 days of treatment and completed recovery in 20 to 30 days, followed by the cure. One year after the treatment, the dogs did not have recurrence of the syndrome. This report shows the use of betahistine dihydrochloride in dogs with peripheral vestibular syndrome, with rapid clinical recover, without laboratorial abnormalities or recurrence of the clinical signs .The results encourage the use of betahistine dihydrochloride in the treatment of peripheral vestibular disorders in small animals.KEY WORDS: Betahistine, dog, vestibular syndrome. |
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BETAHISTINE DIHYDROCHLORIDE IN CANINE PERIPHERAL VESTIBULAR SYNDROMEDICLORIDRATO DE BETAISTINA NA SÍNDROME VESTIBULAR PERIFÉRICA CANINAdog vestibular syndromebetahistinecãosíndrome vestibularbetaistinaVestibular disease is a common syndrome in small animals that may resulst of central or peripheral disease. The pathophysiology of peripheral vestibular syndrome is unknown, however it can be related to an abnormal dynamic of endolymphatic fluid or neuritis of the vestibular portion of the VIII cranial nerve. The recovery of neurological sings is slow and, in chronic cases, the neurological deficits can be irreversible. In veterinary medicine, thera are few medical options to treat this condition, however, in Medicine, betahistine dihydrochloride is used to treat peripheral vestibular disorders. These drug was used in four dogs with vestibular syndrome. The results showed clinical improvement in 7 to 10 days of treatment and completed recovery in 20 to 30 days, followed by the cure. One year after the treatment, the dogs did not have recurrence of the syndrome. This report shows the use of betahistine dihydrochloride in dogs with peripheral vestibular syndrome, with rapid clinical recover, without laboratorial abnormalities or recurrence of the clinical signs .The results encourage the use of betahistine dihydrochloride in the treatment of peripheral vestibular disorders in small animals.KEY WORDS: Betahistine, dog, vestibular syndrome. A síndrome vestibular periférica é uma condição clínica comum em cães. Várias doenças podem causar essa síndrome. Entretanto, sua patofisiologia ainda é pouco conhecida. As alterações clínicas geralmente são autolimitantes, a recuperação pode ser longa e, em casos crônicos, os déficits neurológicos podem ser irreversíveis. Em medicina veterinária, há poucas opções terapêuticas. Na Medicina, o dicloridrato de betaístina é amplamente utilizado. Essa medicação foi empregada em seis cães com síndrome vestibular periférica. Os resultados mostraram melhora clínica com sete a dez dias de tratamento e recuperação quase completa entre vinte e trinta dias. Este trabalho descreve a utilização da betaistina em cães com síndrome vestibular periférica, a rápida melhora clínica e ausência de efeitos adversos. Os resultados obtidos parecem justificar o uso de dicloridrato de betaistina na terapia de distúrbios vestibulares periféricos em animais de companhia.PALAVRAS-CHAVES: Betaistina, cão, síndrome vestibular. Universidade Federal de Goiás2010-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado por paresrelato de casoinfo:eu-repo/semantics/otherapplication/pdftext/htmlhttps://revistas.ufg.br/vet/article/view/175310.5216/cab.v11i1.1753Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 11 No. 1 (2010); 239 - 244Ciência Animal Brasileira / Brazilian Animal Science; v. 11 n. 1 (2010); 239 - 2441809-68911518-2797reponame:Ciência animal brasileira (Online)instname:Universidade Federal de Goiás (UFG)instacron:UFGporhttps://revistas.ufg.br/vet/article/view/1753/6561https://revistas.ufg.br/vet/article/view/1753/8119Brum, Alexandre Martini dePascon, João Paulo da ExaltaçãoChampion, TatianaTinucci-Costa, Mirelainfo:eu-repo/semantics/openAccess2010-04-02T01:31:57Zoai:ojs.revistas.ufg.br:article/1753Revistahttps://revistas.ufg.br/vetPUBhttps://revistas.ufg.br/vet/oai||revistacab@gmail.com1809-68911518-2797opendoar:2024-05-21T19:54:59.013656Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)true |
dc.title.none.fl_str_mv |
BETAHISTINE DIHYDROCHLORIDE IN CANINE PERIPHERAL VESTIBULAR SYNDROME DICLORIDRATO DE BETAISTINA NA SÍNDROME VESTIBULAR PERIFÉRICA CANINA |
title |
BETAHISTINE DIHYDROCHLORIDE IN CANINE PERIPHERAL VESTIBULAR SYNDROME |
spellingShingle |
BETAHISTINE DIHYDROCHLORIDE IN CANINE PERIPHERAL VESTIBULAR SYNDROME Brum, Alexandre Martini de dog vestibular syndrome betahistine cão síndrome vestibular betaistina |
title_short |
BETAHISTINE DIHYDROCHLORIDE IN CANINE PERIPHERAL VESTIBULAR SYNDROME |
title_full |
BETAHISTINE DIHYDROCHLORIDE IN CANINE PERIPHERAL VESTIBULAR SYNDROME |
title_fullStr |
BETAHISTINE DIHYDROCHLORIDE IN CANINE PERIPHERAL VESTIBULAR SYNDROME |
title_full_unstemmed |
BETAHISTINE DIHYDROCHLORIDE IN CANINE PERIPHERAL VESTIBULAR SYNDROME |
title_sort |
BETAHISTINE DIHYDROCHLORIDE IN CANINE PERIPHERAL VESTIBULAR SYNDROME |
author |
Brum, Alexandre Martini de |
author_facet |
Brum, Alexandre Martini de Pascon, João Paulo da Exaltação Champion, Tatiana Tinucci-Costa, Mirela |
author_role |
author |
author2 |
Pascon, João Paulo da Exaltação Champion, Tatiana Tinucci-Costa, Mirela |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Brum, Alexandre Martini de Pascon, João Paulo da Exaltação Champion, Tatiana Tinucci-Costa, Mirela |
dc.subject.por.fl_str_mv |
dog vestibular syndrome betahistine cão síndrome vestibular betaistina |
topic |
dog vestibular syndrome betahistine cão síndrome vestibular betaistina |
description |
Vestibular disease is a common syndrome in small animals that may resulst of central or peripheral disease. The pathophysiology of peripheral vestibular syndrome is unknown, however it can be related to an abnormal dynamic of endolymphatic fluid or neuritis of the vestibular portion of the VIII cranial nerve. The recovery of neurological sings is slow and, in chronic cases, the neurological deficits can be irreversible. In veterinary medicine, thera are few medical options to treat this condition, however, in Medicine, betahistine dihydrochloride is used to treat peripheral vestibular disorders. These drug was used in four dogs with vestibular syndrome. The results showed clinical improvement in 7 to 10 days of treatment and completed recovery in 20 to 30 days, followed by the cure. One year after the treatment, the dogs did not have recurrence of the syndrome. This report shows the use of betahistine dihydrochloride in dogs with peripheral vestibular syndrome, with rapid clinical recover, without laboratorial abnormalities or recurrence of the clinical signs .The results encourage the use of betahistine dihydrochloride in the treatment of peripheral vestibular disorders in small animals.KEY WORDS: Betahistine, dog, vestibular syndrome. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Avaliado por pares relato de caso info:eu-repo/semantics/other |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistas.ufg.br/vet/article/view/1753 10.5216/cab.v11i1.1753 |
url |
https://revistas.ufg.br/vet/article/view/1753 |
identifier_str_mv |
10.5216/cab.v11i1.1753 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revistas.ufg.br/vet/article/view/1753/6561 https://revistas.ufg.br/vet/article/view/1753/8119 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf text/html |
dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.source.none.fl_str_mv |
Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 11 No. 1 (2010); 239 - 244 Ciência Animal Brasileira / Brazilian Animal Science; v. 11 n. 1 (2010); 239 - 244 1809-6891 1518-2797 reponame:Ciência animal brasileira (Online) instname:Universidade Federal de Goiás (UFG) instacron:UFG |
instname_str |
Universidade Federal de Goiás (UFG) |
instacron_str |
UFG |
institution |
UFG |
reponame_str |
Ciência animal brasileira (Online) |
collection |
Ciência animal brasileira (Online) |
repository.name.fl_str_mv |
Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG) |
repository.mail.fl_str_mv |
||revistacab@gmail.com |
_version_ |
1799874783865733120 |