PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE

Detalhes bibliográficos
Autor(a) principal: Nogueira, Geison Morel
Data de Publicação: 2019
Outros Autores: Perri, Sílvia Helena Venturoli, Dos Santos, Paulo Sérgio Patto, Rodrigues, Celso Antonio
Tipo de documento: Artigo
Idioma: por
Título da fonte: Ciência animal brasileira (Online)
Texto Completo: https://revistas.ufg.br/vet/article/view/44627
Resumo: The use of opioids for analgesia is limited or undefined in ruminants. The aim of this study was to compare two analgesics opioids, morphine and tramadol, based on the clinical and pedometric evaluations of animals submitted to a temporary experimental arthritis and synovitis, developed at the distal interphalangeal joint after an intra-articular administration of amphotericin B. Six animals were used in two different treatments, using morphine, dose of 0,5 mg/kg, and twenty days later, tramadol, dose of 1,8 mg/kg, both intramuscularly. The animals were evaluated at 3-hour intervals for a total of 27 hours, observing the physiological parameters, ambulation and pedometer activity. Lameness and pedometer variations were observed in both treatments. Based on the variables of pedometric activity, a pattern of restlessness compatible with podal nociception was observed, and there was no interference of any of the drugs on lameness. It was concluded that morphine and tramadol, at the tested doses, were incapable of interfering in the lameness attenuation during the maximum painful stimulation moment in this experimental protocol of orthopedic pain.Keywords: Amphotericin B; arthritis; lameness; pain; synovitis.
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spelling PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINEPEDOMETRIA APLICADA A ESTUDO COMPARATIVO ENTRE MORFINA E TRAMADOL EM BOVINOSThe use of opioids for analgesia is limited or undefined in ruminants. The aim of this study was to compare two analgesics opioids, morphine and tramadol, based on the clinical and pedometric evaluations of animals submitted to a temporary experimental arthritis and synovitis, developed at the distal interphalangeal joint after an intra-articular administration of amphotericin B. Six animals were used in two different treatments, using morphine, dose of 0,5 mg/kg, and twenty days later, tramadol, dose of 1,8 mg/kg, both intramuscularly. The animals were evaluated at 3-hour intervals for a total of 27 hours, observing the physiological parameters, ambulation and pedometer activity. Lameness and pedometer variations were observed in both treatments. Based on the variables of pedometric activity, a pattern of restlessness compatible with podal nociception was observed, and there was no interference of any of the drugs on lameness. It was concluded that morphine and tramadol, at the tested doses, were incapable of interfering in the lameness attenuation during the maximum painful stimulation moment in this experimental protocol of orthopedic pain.Keywords: Amphotericin B; arthritis; lameness; pain; synovitis.A analgesia com opioides é limitada ou indefinida em ruminantes. Neste trabalho, objetivou-se a realização de um estudo comparativo entre dois analgésicos opioides: a morfina e o tramadol, com base nas avaliações clínica e pedométrica de animais submetidos a artrite e sinovite experimental transitórias, desenvolvidas na articulação interfalângica distal, após administração intra-articular de anfotericina B. Utilizou-se seis animais, em dois tratamentos distintos, com morfina, na dose de 0,5 mg/kg e 20 dias depois com tramadol, na dose de 1,8 mg/kg, ambos via intramuscular. Os animais foram avaliados em intervalos de três horas, num total de 27 horas, observando-se parâmetros fisiológicos, deambulação e atividade pedométrica. Claudicação e alterações pedométricas foram observadas para ambos os fármacos. Por meio das variáveis da atividade pedométrica, observou-se um padrão de inquietação compatível com nocicepção podal, não havendo a interferência dos fármacos sobre a claudicação. Concluiu-se que a morfina e o tramadol, nas doses testadas, foram incapazes de interferir na atenuação do grau de claudicação no momento de máxima estimulação dolorosa, frente ao modelo experimental de dor ortopédica.Palavras-chave: Anfotericina B; artrite; claudicação; dor; sinovite.Universidade Federal de Goiás2019-08-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/htmlhttps://revistas.ufg.br/vet/article/view/44627Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 20 (2019): Continuous publication; 1-11Ciência Animal Brasileira / Brazilian Animal Science; v. 20 (2019): Publicação contínua; 1-111809-68911518-2797reponame:Ciência animal brasileira (Online)instname:Universidade Federal de Goiás (UFG)instacron:UFGporhttps://revistas.ufg.br/vet/article/view/44627/33587https://revistas.ufg.br/vet/article/view/44627/33588Copyright (c) 2019 Ciência Animal Brasileirainfo:eu-repo/semantics/openAccessNogueira, Geison MorelPerri, Sílvia Helena VenturoliDos Santos, Paulo Sérgio PattoRodrigues, Celso Antonio2023-03-23T18:49:21Zoai:ojs.revistas.ufg.br:article/44627Revistahttps://revistas.ufg.br/vetPUBhttps://revistas.ufg.br/vet/oai||revistacab@gmail.com1809-68911518-2797opendoar:2024-05-21T19:56:16.790219Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)true
dc.title.none.fl_str_mv PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE
PEDOMETRIA APLICADA A ESTUDO COMPARATIVO ENTRE MORFINA E TRAMADOL EM BOVINOS
title PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE
spellingShingle PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE
Nogueira, Geison Morel
title_short PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE
title_full PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE
title_fullStr PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE
title_full_unstemmed PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE
title_sort PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE
author Nogueira, Geison Morel
author_facet Nogueira, Geison Morel
Perri, Sílvia Helena Venturoli
Dos Santos, Paulo Sérgio Patto
Rodrigues, Celso Antonio
author_role author
author2 Perri, Sílvia Helena Venturoli
Dos Santos, Paulo Sérgio Patto
Rodrigues, Celso Antonio
author2_role author
author
author
dc.contributor.author.fl_str_mv Nogueira, Geison Morel
Perri, Sílvia Helena Venturoli
Dos Santos, Paulo Sérgio Patto
Rodrigues, Celso Antonio
description The use of opioids for analgesia is limited or undefined in ruminants. The aim of this study was to compare two analgesics opioids, morphine and tramadol, based on the clinical and pedometric evaluations of animals submitted to a temporary experimental arthritis and synovitis, developed at the distal interphalangeal joint after an intra-articular administration of amphotericin B. Six animals were used in two different treatments, using morphine, dose of 0,5 mg/kg, and twenty days later, tramadol, dose of 1,8 mg/kg, both intramuscularly. The animals were evaluated at 3-hour intervals for a total of 27 hours, observing the physiological parameters, ambulation and pedometer activity. Lameness and pedometer variations were observed in both treatments. Based on the variables of pedometric activity, a pattern of restlessness compatible with podal nociception was observed, and there was no interference of any of the drugs on lameness. It was concluded that morphine and tramadol, at the tested doses, were incapable of interfering in the lameness attenuation during the maximum painful stimulation moment in this experimental protocol of orthopedic pain.Keywords: Amphotericin B; arthritis; lameness; pain; synovitis.
publishDate 2019
dc.date.none.fl_str_mv 2019-08-29
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistas.ufg.br/vet/article/view/44627
url https://revistas.ufg.br/vet/article/view/44627
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revistas.ufg.br/vet/article/view/44627/33587
https://revistas.ufg.br/vet/article/view/44627/33588
dc.rights.driver.fl_str_mv Copyright (c) 2019 Ciência Animal Brasileira
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2019 Ciência Animal Brasileira
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
text/html
dc.publisher.none.fl_str_mv Universidade Federal de Goiás
publisher.none.fl_str_mv Universidade Federal de Goiás
dc.source.none.fl_str_mv Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 20 (2019): Continuous publication; 1-11
Ciência Animal Brasileira / Brazilian Animal Science; v. 20 (2019): Publicação contínua; 1-11
1809-6891
1518-2797
reponame:Ciência animal brasileira (Online)
instname:Universidade Federal de Goiás (UFG)
instacron:UFG
instname_str Universidade Federal de Goiás (UFG)
instacron_str UFG
institution UFG
reponame_str Ciência animal brasileira (Online)
collection Ciência animal brasileira (Online)
repository.name.fl_str_mv Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)
repository.mail.fl_str_mv ||revistacab@gmail.com
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