PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE
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Data de Publicação: | 2019 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Ciência animal brasileira (Online) |
Texto Completo: | https://revistas.ufg.br/vet/article/view/44627 |
Resumo: | The use of opioids for analgesia is limited or undefined in ruminants. The aim of this study was to compare two analgesics opioids, morphine and tramadol, based on the clinical and pedometric evaluations of animals submitted to a temporary experimental arthritis and synovitis, developed at the distal interphalangeal joint after an intra-articular administration of amphotericin B. Six animals were used in two different treatments, using morphine, dose of 0,5 mg/kg, and twenty days later, tramadol, dose of 1,8 mg/kg, both intramuscularly. The animals were evaluated at 3-hour intervals for a total of 27 hours, observing the physiological parameters, ambulation and pedometer activity. Lameness and pedometer variations were observed in both treatments. Based on the variables of pedometric activity, a pattern of restlessness compatible with podal nociception was observed, and there was no interference of any of the drugs on lameness. It was concluded that morphine and tramadol, at the tested doses, were incapable of interfering in the lameness attenuation during the maximum painful stimulation moment in this experimental protocol of orthopedic pain.Keywords: Amphotericin B; arthritis; lameness; pain; synovitis. |
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PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINEPEDOMETRIA APLICADA A ESTUDO COMPARATIVO ENTRE MORFINA E TRAMADOL EM BOVINOSThe use of opioids for analgesia is limited or undefined in ruminants. The aim of this study was to compare two analgesics opioids, morphine and tramadol, based on the clinical and pedometric evaluations of animals submitted to a temporary experimental arthritis and synovitis, developed at the distal interphalangeal joint after an intra-articular administration of amphotericin B. Six animals were used in two different treatments, using morphine, dose of 0,5 mg/kg, and twenty days later, tramadol, dose of 1,8 mg/kg, both intramuscularly. The animals were evaluated at 3-hour intervals for a total of 27 hours, observing the physiological parameters, ambulation and pedometer activity. Lameness and pedometer variations were observed in both treatments. Based on the variables of pedometric activity, a pattern of restlessness compatible with podal nociception was observed, and there was no interference of any of the drugs on lameness. It was concluded that morphine and tramadol, at the tested doses, were incapable of interfering in the lameness attenuation during the maximum painful stimulation moment in this experimental protocol of orthopedic pain.Keywords: Amphotericin B; arthritis; lameness; pain; synovitis.A analgesia com opioides é limitada ou indefinida em ruminantes. Neste trabalho, objetivou-se a realização de um estudo comparativo entre dois analgésicos opioides: a morfina e o tramadol, com base nas avaliações clínica e pedométrica de animais submetidos a artrite e sinovite experimental transitórias, desenvolvidas na articulação interfalângica distal, após administração intra-articular de anfotericina B. Utilizou-se seis animais, em dois tratamentos distintos, com morfina, na dose de 0,5 mg/kg e 20 dias depois com tramadol, na dose de 1,8 mg/kg, ambos via intramuscular. Os animais foram avaliados em intervalos de três horas, num total de 27 horas, observando-se parâmetros fisiológicos, deambulação e atividade pedométrica. Claudicação e alterações pedométricas foram observadas para ambos os fármacos. Por meio das variáveis da atividade pedométrica, observou-se um padrão de inquietação compatível com nocicepção podal, não havendo a interferência dos fármacos sobre a claudicação. Concluiu-se que a morfina e o tramadol, nas doses testadas, foram incapazes de interferir na atenuação do grau de claudicação no momento de máxima estimulação dolorosa, frente ao modelo experimental de dor ortopédica.Palavras-chave: Anfotericina B; artrite; claudicação; dor; sinovite.Universidade Federal de Goiás2019-08-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/htmlhttps://revistas.ufg.br/vet/article/view/44627Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 20 (2019): Continuous publication; 1-11Ciência Animal Brasileira / Brazilian Animal Science; v. 20 (2019): Publicação contínua; 1-111809-68911518-2797reponame:Ciência animal brasileira (Online)instname:Universidade Federal de Goiás (UFG)instacron:UFGporhttps://revistas.ufg.br/vet/article/view/44627/33587https://revistas.ufg.br/vet/article/view/44627/33588Copyright (c) 2019 Ciência Animal Brasileirainfo:eu-repo/semantics/openAccessNogueira, Geison MorelPerri, Sílvia Helena VenturoliDos Santos, Paulo Sérgio PattoRodrigues, Celso Antonio2023-03-23T18:49:21Zoai:ojs.revistas.ufg.br:article/44627Revistahttps://revistas.ufg.br/vetPUBhttps://revistas.ufg.br/vet/oai||revistacab@gmail.com1809-68911518-2797opendoar:2024-05-21T19:56:16.790219Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)true |
dc.title.none.fl_str_mv |
PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE PEDOMETRIA APLICADA A ESTUDO COMPARATIVO ENTRE MORFINA E TRAMADOL EM BOVINOS |
title |
PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE |
spellingShingle |
PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE Nogueira, Geison Morel |
title_short |
PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE |
title_full |
PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE |
title_fullStr |
PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE |
title_full_unstemmed |
PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE |
title_sort |
PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE |
author |
Nogueira, Geison Morel |
author_facet |
Nogueira, Geison Morel Perri, Sílvia Helena Venturoli Dos Santos, Paulo Sérgio Patto Rodrigues, Celso Antonio |
author_role |
author |
author2 |
Perri, Sílvia Helena Venturoli Dos Santos, Paulo Sérgio Patto Rodrigues, Celso Antonio |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Nogueira, Geison Morel Perri, Sílvia Helena Venturoli Dos Santos, Paulo Sérgio Patto Rodrigues, Celso Antonio |
description |
The use of opioids for analgesia is limited or undefined in ruminants. The aim of this study was to compare two analgesics opioids, morphine and tramadol, based on the clinical and pedometric evaluations of animals submitted to a temporary experimental arthritis and synovitis, developed at the distal interphalangeal joint after an intra-articular administration of amphotericin B. Six animals were used in two different treatments, using morphine, dose of 0,5 mg/kg, and twenty days later, tramadol, dose of 1,8 mg/kg, both intramuscularly. The animals were evaluated at 3-hour intervals for a total of 27 hours, observing the physiological parameters, ambulation and pedometer activity. Lameness and pedometer variations were observed in both treatments. Based on the variables of pedometric activity, a pattern of restlessness compatible with podal nociception was observed, and there was no interference of any of the drugs on lameness. It was concluded that morphine and tramadol, at the tested doses, were incapable of interfering in the lameness attenuation during the maximum painful stimulation moment in this experimental protocol of orthopedic pain.Keywords: Amphotericin B; arthritis; lameness; pain; synovitis. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-08-29 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistas.ufg.br/vet/article/view/44627 |
url |
https://revistas.ufg.br/vet/article/view/44627 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revistas.ufg.br/vet/article/view/44627/33587 https://revistas.ufg.br/vet/article/view/44627/33588 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2019 Ciência Animal Brasileira info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2019 Ciência Animal Brasileira |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf text/html |
dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.source.none.fl_str_mv |
Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 20 (2019): Continuous publication; 1-11 Ciência Animal Brasileira / Brazilian Animal Science; v. 20 (2019): Publicação contínua; 1-11 1809-6891 1518-2797 reponame:Ciência animal brasileira (Online) instname:Universidade Federal de Goiás (UFG) instacron:UFG |
instname_str |
Universidade Federal de Goiás (UFG) |
instacron_str |
UFG |
institution |
UFG |
reponame_str |
Ciência animal brasileira (Online) |
collection |
Ciência animal brasileira (Online) |
repository.name.fl_str_mv |
Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG) |
repository.mail.fl_str_mv |
||revistacab@gmail.com |
_version_ |
1799874789335105536 |