AZITHROMYCIN IN THE TREATMENT OF MONOCYTIC EHRLICHIOSIS IN NATURALLY INFECTED DOGS
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Ciência animal brasileira (Online) |
Texto Completo: | https://revistas.ufg.br/vet/article/view/5553 |
Resumo: | The aims of this study were to evaluate the effectiveness of treatment with azithromycin in dogs naturally infected with E. canis, and to analyse the clinical and hematological changes the animals would show. Ten dogs with positive diagnosis for E. canis through Elisa Snap 4Dx test were distributed into two groups, untreated and treated with azithromycin, 20 mg/kg, orally once a day for seven days. In addition to the physical exam, complete blood counts (CBC), smears made out from blood of the ear margin in order to detect ehrlichial morulae and nested PCR before treatment and post-treatment were performed. We found that the treatment was not effective, since the clinical signs did not disappear, as well as there was no return to normal values of the CBC in treated animas, neither the elimination of E. canis from the infected animals.Keywords: azithromycin; Ehrlichia canis; PCR; Dogs. |
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Ciência animal brasileira (Online) |
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AZITHROMYCIN IN THE TREATMENT OF MONOCYTIC EHRLICHIOSIS IN NATURALLY INFECTED DOGSAZITROMICINA NO TRATAMENTO DA ERLICHIOSE MONOCÍTICA EM CÃES NATURALMENTE INFECTADOSAnimal SanityClínica de Pequenos AnimaisThe aims of this study were to evaluate the effectiveness of treatment with azithromycin in dogs naturally infected with E. canis, and to analyse the clinical and hematological changes the animals would show. Ten dogs with positive diagnosis for E. canis through Elisa Snap 4Dx test were distributed into two groups, untreated and treated with azithromycin, 20 mg/kg, orally once a day for seven days. In addition to the physical exam, complete blood counts (CBC), smears made out from blood of the ear margin in order to detect ehrlichial morulae and nested PCR before treatment and post-treatment were performed. We found that the treatment was not effective, since the clinical signs did not disappear, as well as there was no return to normal values of the CBC in treated animas, neither the elimination of E. canis from the infected animals.Keywords: azithromycin; Ehrlichia canis; PCR; Dogs.Os objetivos deste trabalho foram avaliar a eficácia do tratamento com azitromicina em cães naturalmente infectados por E. canis e acompanhar a evolução clínico-hematológica dos animais. Dez cães, com diagnóstico positivo para E. canis por meio do teste de Elisa Snap 4Dx, foram distribuídos em dois grupos, sem tratamento e tratados com azitromicina, 20 mg/kg, via oral, uma vez ao dia, durante sete dias. Além do exame físico diário foram realizados hemogramas, esfregaços de ponta de orelha para a pesquisa de mórulas e nested PCR antes do tratamento e pós-tratamento. Verificou-se que o tratamento não foi eficiente, uma vez que não desapareceram os sinais clínicos, assim como não houve retorno à normalidade dos valores do hemograma nos cães, assim como ausência de eliminação de E. canis.Palavras-chave: Azitromicina; Ehrlichia canis; PCR; Cães.Universidade Federal de Goiás2014-12-23info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionResearchAvaliado por paresPesquisa Científicaapplication/pdftext/htmlhttps://revistas.ufg.br/vet/article/view/555310.1590/cab.v15i4.5553Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 15 No. 4 (2014); 458-465Ciência Animal Brasileira / Brazilian Animal Science; v. 15 n. 4 (2014); 458-4651809-68911518-2797reponame:Ciência animal brasileira (Online)instname:Universidade Federal de Goiás (UFG)instacron:UFGporhttps://revistas.ufg.br/vet/article/view/5553/17680https://revistas.ufg.br/vet/article/view/5553/17681Cantadori, Daniela TorresOsório, Ana Luiza RosaBabo-Terra, Veronica Jorgeinfo:eu-repo/semantics/openAccess2014-12-23T23:51:13Zoai:ojs.revistas.ufg.br:article/5553Revistahttps://revistas.ufg.br/vetPUBhttps://revistas.ufg.br/vet/oai||revistacab@gmail.com1809-68911518-2797opendoar:2024-05-21T19:55:21.884726Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)true |
dc.title.none.fl_str_mv |
AZITHROMYCIN IN THE TREATMENT OF MONOCYTIC EHRLICHIOSIS IN NATURALLY INFECTED DOGS AZITROMICINA NO TRATAMENTO DA ERLICHIOSE MONOCÍTICA EM CÃES NATURALMENTE INFECTADOS |
title |
AZITHROMYCIN IN THE TREATMENT OF MONOCYTIC EHRLICHIOSIS IN NATURALLY INFECTED DOGS |
spellingShingle |
AZITHROMYCIN IN THE TREATMENT OF MONOCYTIC EHRLICHIOSIS IN NATURALLY INFECTED DOGS Cantadori, Daniela Torres Animal Sanity Clínica de Pequenos Animais |
title_short |
AZITHROMYCIN IN THE TREATMENT OF MONOCYTIC EHRLICHIOSIS IN NATURALLY INFECTED DOGS |
title_full |
AZITHROMYCIN IN THE TREATMENT OF MONOCYTIC EHRLICHIOSIS IN NATURALLY INFECTED DOGS |
title_fullStr |
AZITHROMYCIN IN THE TREATMENT OF MONOCYTIC EHRLICHIOSIS IN NATURALLY INFECTED DOGS |
title_full_unstemmed |
AZITHROMYCIN IN THE TREATMENT OF MONOCYTIC EHRLICHIOSIS IN NATURALLY INFECTED DOGS |
title_sort |
AZITHROMYCIN IN THE TREATMENT OF MONOCYTIC EHRLICHIOSIS IN NATURALLY INFECTED DOGS |
author |
Cantadori, Daniela Torres |
author_facet |
Cantadori, Daniela Torres Osório, Ana Luiza Rosa Babo-Terra, Veronica Jorge |
author_role |
author |
author2 |
Osório, Ana Luiza Rosa Babo-Terra, Veronica Jorge |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Cantadori, Daniela Torres Osório, Ana Luiza Rosa Babo-Terra, Veronica Jorge |
dc.subject.por.fl_str_mv |
Animal Sanity Clínica de Pequenos Animais |
topic |
Animal Sanity Clínica de Pequenos Animais |
description |
The aims of this study were to evaluate the effectiveness of treatment with azithromycin in dogs naturally infected with E. canis, and to analyse the clinical and hematological changes the animals would show. Ten dogs with positive diagnosis for E. canis through Elisa Snap 4Dx test were distributed into two groups, untreated and treated with azithromycin, 20 mg/kg, orally once a day for seven days. In addition to the physical exam, complete blood counts (CBC), smears made out from blood of the ear margin in order to detect ehrlichial morulae and nested PCR before treatment and post-treatment were performed. We found that the treatment was not effective, since the clinical signs did not disappear, as well as there was no return to normal values of the CBC in treated animas, neither the elimination of E. canis from the infected animals.Keywords: azithromycin; Ehrlichia canis; PCR; Dogs. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-12-23 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Research Avaliado por pares Pesquisa Científica |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistas.ufg.br/vet/article/view/5553 10.1590/cab.v15i4.5553 |
url |
https://revistas.ufg.br/vet/article/view/5553 |
identifier_str_mv |
10.1590/cab.v15i4.5553 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revistas.ufg.br/vet/article/view/5553/17680 https://revistas.ufg.br/vet/article/view/5553/17681 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf text/html |
dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.source.none.fl_str_mv |
Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 15 No. 4 (2014); 458-465 Ciência Animal Brasileira / Brazilian Animal Science; v. 15 n. 4 (2014); 458-465 1809-6891 1518-2797 reponame:Ciência animal brasileira (Online) instname:Universidade Federal de Goiás (UFG) instacron:UFG |
instname_str |
Universidade Federal de Goiás (UFG) |
instacron_str |
UFG |
institution |
UFG |
reponame_str |
Ciência animal brasileira (Online) |
collection |
Ciência animal brasileira (Online) |
repository.name.fl_str_mv |
Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG) |
repository.mail.fl_str_mv |
||revistacab@gmail.com |
_version_ |
1799874785582252032 |