EFFECTS OF A NEW INTRAVENOUS ELECTROLYTE SOLUTION FOR USE IN VETERINARY PRACTICE ON THE ELECTROLYTE AND ACID-BASE BALANCES OF HEALTHY CATTLE

Detalhes bibliográficos
Autor(a) principal: Pereira, Priscilla Fajardo Valente
Data de Publicação: 2017
Outros Autores: Bessegatto, José Antonio, Bregadioli, Gabriela de Castro, Marcondes, José Guilherme do Rego, Fernandes, Thiago Marquez, Balarin, Mara Regina Stipp, Flaiban, Karina Keller Marques da Costa, Lisbôa, Júlio Augusto Naylor
Tipo de documento: Artigo
Idioma: por
Título da fonte: Ciência animal brasileira (Online)
Texto Completo: https://revistas.ufg.br/vet/article/view/e-32785
Resumo: The effects of a new intravenous polyionic solution on electrolyte and acid-base balances in cattle were evaluated. Eight healthy adult, crossbred Bos taurus cattle received two treatments in a cross-over design: isotonic saline solution (IS) and test solution (TS) with 145 mEq of Na+, 5 mEq of K+, 4 mEq of Ca++, 2 mEq of Mg++, 96 mEq of Cl-, 60 mEq of lactate, 50 g of dextrose, and 4 mg of cyanocobalamin per liter. The solutions were IV infused in a volume corresponding to 5% of BW, through 3 hours. Venous blood samples were taken before the infusion and 3, 6, 9, and 24 hours after the beginning of the infusion. Glucose, L-lactate, Ca, P, Mg, pH, pCO2, HCO3-, BE, Na+, K+, Cl-, and Ca++ were measured. Data were analyzed through repeated measures ANOVA. IS caused acidifying effect due to hyperchloremia and decreased plasma strong ion difference (SID). On the contrary, TS induced mild and transient alkalinization without changes in Na+ and Cl- plasma levels. Transient hypokalemia and hyperglycemia were presented at the end of the ST infusion but did not provoke apparent clinical signs. We concluded that TS is a safe choice for fluid therapy in cattle, inducing low magnitude iatrogenic changes as an advantage. Keywords: blood gas analyses, electrolytes, intravenous fluid therapy.
id UFG-7_bd979ade10e0648094aba4a953d8d49e
oai_identifier_str oai:ojs.revistas.ufg.br:article/32785
network_acronym_str UFG-7
network_name_str Ciência animal brasileira (Online)
repository_id_str
spelling EFFECTS OF A NEW INTRAVENOUS ELECTROLYTE SOLUTION FOR USE IN VETERINARY PRACTICE ON THE ELECTROLYTE AND ACID-BASE BALANCES OF HEALTHY CATTLENOVA SOLUÇÃO ELETROLÍTICA INTRAVENOSA PARA USO VETERINÁRIO: EFEITOS SOBRE O PERFIL ELETROLÍTICO E ÁCIDO BASE EM BOVINOS ADULTOS HÍGIDOSAnimal SanityTerapia com FluidosEletrólitosDiferença de Íons FortesHidrataçãoThe effects of a new intravenous polyionic solution on electrolyte and acid-base balances in cattle were evaluated. Eight healthy adult, crossbred Bos taurus cattle received two treatments in a cross-over design: isotonic saline solution (IS) and test solution (TS) with 145 mEq of Na+, 5 mEq of K+, 4 mEq of Ca++, 2 mEq of Mg++, 96 mEq of Cl-, 60 mEq of lactate, 50 g of dextrose, and 4 mg of cyanocobalamin per liter. The solutions were IV infused in a volume corresponding to 5% of BW, through 3 hours. Venous blood samples were taken before the infusion and 3, 6, 9, and 24 hours after the beginning of the infusion. Glucose, L-lactate, Ca, P, Mg, pH, pCO2, HCO3-, BE, Na+, K+, Cl-, and Ca++ were measured. Data were analyzed through repeated measures ANOVA. IS caused acidifying effect due to hyperchloremia and decreased plasma strong ion difference (SID). On the contrary, TS induced mild and transient alkalinization without changes in Na+ and Cl- plasma levels. Transient hypokalemia and hyperglycemia were presented at the end of the ST infusion but did not provoke apparent clinical signs. We concluded that TS is a safe choice for fluid therapy in cattle, inducing low magnitude iatrogenic changes as an advantage. Keywords: blood gas analyses, electrolytes, intravenous fluid therapy.Objetivou-se avaliar os efeitos de uma nova solução hidratante intravenosa sobre os equilíbrios eletrolítico e ácido-base de bovinos. Para tanto, oito animais adultos hígidos, mestiços taurinos foram submetidos a dois tratamentos em delineamento cross-over: solução salina isotônica (SI) e solução teste (ST) composta por 145 mEq de Na+, 5 mEq de K+, 4 mEq de Ca++, 2 mEq de Mg++, 96 mEq de Cl-, 60 mEq de lactato, 50 g de dextrose e 4 mg de cianocobalamina por litro. As soluções foram administradas por via intravenosa, em volume correspondente a 5% do peso corporal, durante três horas de infusão contínua. Amostras de sangue venoso foram colhidas antes da infusão e três, seis, nove e 24 horas após o início da infusão para determinações de glicose, lactato L, Ca, P, Mg, pH, pCO2, HCO3-, BE, Na+, K+, Cl- e Ca++. Os resultados foram analisados por análise de variâncias de medidas repetidas. Ao contrário da SI, que causou hipercloremia e redução da diferença de íons fortes no plasma (SID), determinando efeito acidificante, a ST gerou alcalinização leve e transitória e não provocou alteração das concentrações de Na+ e de Cl-. A hipopotassemia e a hiperglicemia, presentes ao final da infusão da ST, foram transitórias e não determinaram sinais clínicos evidentes. Conclui-se que a ST é uma alternativa segura para a terapia com fluidos em bovinos, tendo a vantagem de provocar alterações iatrogênicas de baixa magnitude.Palavras-chave: gasometria, eletrólitos, terapia com fluidos intravenosa.Universidade Federal de Goiás2017-03-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPesquisa CientíficaResearchapplication/pdftext/htmlhttps://revistas.ufg.br/vet/article/view/e-3278510.1590/cab18032785Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 18 (2017): Continuous publicationCiência Animal Brasileira / Brazilian Animal Science; v. 18 (2017): Publicação contínua1809-68911518-2797reponame:Ciência animal brasileira (Online)instname:Universidade Federal de Goiás (UFG)instacron:UFGporhttps://revistas.ufg.br/vet/article/view/e-32785/22532https://revistas.ufg.br/vet/article/view/e-32785/22533Pereira, Priscilla Fajardo ValenteBessegatto, José AntonioBregadioli, Gabriela de CastroMarcondes, José Guilherme do RegoFernandes, Thiago MarquezBalarin, Mara Regina StippFlaiban, Karina Keller Marques da CostaLisbôa, Júlio Augusto Naylorinfo:eu-repo/semantics/openAccess2023-06-07T18:48:26Zoai:ojs.revistas.ufg.br:article/32785Revistahttps://revistas.ufg.br/vetPUBhttps://revistas.ufg.br/vet/oai||revistacab@gmail.com1809-68911518-2797opendoar:2024-05-21T19:56:07.974637Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)true
dc.title.none.fl_str_mv EFFECTS OF A NEW INTRAVENOUS ELECTROLYTE SOLUTION FOR USE IN VETERINARY PRACTICE ON THE ELECTROLYTE AND ACID-BASE BALANCES OF HEALTHY CATTLE
NOVA SOLUÇÃO ELETROLÍTICA INTRAVENOSA PARA USO VETERINÁRIO: EFEITOS SOBRE O PERFIL ELETROLÍTICO E ÁCIDO BASE EM BOVINOS ADULTOS HÍGIDOS
title EFFECTS OF A NEW INTRAVENOUS ELECTROLYTE SOLUTION FOR USE IN VETERINARY PRACTICE ON THE ELECTROLYTE AND ACID-BASE BALANCES OF HEALTHY CATTLE
spellingShingle EFFECTS OF A NEW INTRAVENOUS ELECTROLYTE SOLUTION FOR USE IN VETERINARY PRACTICE ON THE ELECTROLYTE AND ACID-BASE BALANCES OF HEALTHY CATTLE
Pereira, Priscilla Fajardo Valente
Animal Sanity
Terapia com Fluidos
Eletrólitos
Diferença de Íons Fortes
Hidratação
title_short EFFECTS OF A NEW INTRAVENOUS ELECTROLYTE SOLUTION FOR USE IN VETERINARY PRACTICE ON THE ELECTROLYTE AND ACID-BASE BALANCES OF HEALTHY CATTLE
title_full EFFECTS OF A NEW INTRAVENOUS ELECTROLYTE SOLUTION FOR USE IN VETERINARY PRACTICE ON THE ELECTROLYTE AND ACID-BASE BALANCES OF HEALTHY CATTLE
title_fullStr EFFECTS OF A NEW INTRAVENOUS ELECTROLYTE SOLUTION FOR USE IN VETERINARY PRACTICE ON THE ELECTROLYTE AND ACID-BASE BALANCES OF HEALTHY CATTLE
title_full_unstemmed EFFECTS OF A NEW INTRAVENOUS ELECTROLYTE SOLUTION FOR USE IN VETERINARY PRACTICE ON THE ELECTROLYTE AND ACID-BASE BALANCES OF HEALTHY CATTLE
title_sort EFFECTS OF A NEW INTRAVENOUS ELECTROLYTE SOLUTION FOR USE IN VETERINARY PRACTICE ON THE ELECTROLYTE AND ACID-BASE BALANCES OF HEALTHY CATTLE
author Pereira, Priscilla Fajardo Valente
author_facet Pereira, Priscilla Fajardo Valente
Bessegatto, José Antonio
Bregadioli, Gabriela de Castro
Marcondes, José Guilherme do Rego
Fernandes, Thiago Marquez
Balarin, Mara Regina Stipp
Flaiban, Karina Keller Marques da Costa
Lisbôa, Júlio Augusto Naylor
author_role author
author2 Bessegatto, José Antonio
Bregadioli, Gabriela de Castro
Marcondes, José Guilherme do Rego
Fernandes, Thiago Marquez
Balarin, Mara Regina Stipp
Flaiban, Karina Keller Marques da Costa
Lisbôa, Júlio Augusto Naylor
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Pereira, Priscilla Fajardo Valente
Bessegatto, José Antonio
Bregadioli, Gabriela de Castro
Marcondes, José Guilherme do Rego
Fernandes, Thiago Marquez
Balarin, Mara Regina Stipp
Flaiban, Karina Keller Marques da Costa
Lisbôa, Júlio Augusto Naylor
dc.subject.por.fl_str_mv Animal Sanity
Terapia com Fluidos
Eletrólitos
Diferença de Íons Fortes
Hidratação
topic Animal Sanity
Terapia com Fluidos
Eletrólitos
Diferença de Íons Fortes
Hidratação
description The effects of a new intravenous polyionic solution on electrolyte and acid-base balances in cattle were evaluated. Eight healthy adult, crossbred Bos taurus cattle received two treatments in a cross-over design: isotonic saline solution (IS) and test solution (TS) with 145 mEq of Na+, 5 mEq of K+, 4 mEq of Ca++, 2 mEq of Mg++, 96 mEq of Cl-, 60 mEq of lactate, 50 g of dextrose, and 4 mg of cyanocobalamin per liter. The solutions were IV infused in a volume corresponding to 5% of BW, through 3 hours. Venous blood samples were taken before the infusion and 3, 6, 9, and 24 hours after the beginning of the infusion. Glucose, L-lactate, Ca, P, Mg, pH, pCO2, HCO3-, BE, Na+, K+, Cl-, and Ca++ were measured. Data were analyzed through repeated measures ANOVA. IS caused acidifying effect due to hyperchloremia and decreased plasma strong ion difference (SID). On the contrary, TS induced mild and transient alkalinization without changes in Na+ and Cl- plasma levels. Transient hypokalemia and hyperglycemia were presented at the end of the ST infusion but did not provoke apparent clinical signs. We concluded that TS is a safe choice for fluid therapy in cattle, inducing low magnitude iatrogenic changes as an advantage. Keywords: blood gas analyses, electrolytes, intravenous fluid therapy.
publishDate 2017
dc.date.none.fl_str_mv 2017-03-03
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Pesquisa Científica
Research
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistas.ufg.br/vet/article/view/e-32785
10.1590/cab18032785
url https://revistas.ufg.br/vet/article/view/e-32785
identifier_str_mv 10.1590/cab18032785
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revistas.ufg.br/vet/article/view/e-32785/22532
https://revistas.ufg.br/vet/article/view/e-32785/22533
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
text/html
dc.publisher.none.fl_str_mv Universidade Federal de Goiás
publisher.none.fl_str_mv Universidade Federal de Goiás
dc.source.none.fl_str_mv Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 18 (2017): Continuous publication
Ciência Animal Brasileira / Brazilian Animal Science; v. 18 (2017): Publicação contínua
1809-6891
1518-2797
reponame:Ciência animal brasileira (Online)
instname:Universidade Federal de Goiás (UFG)
instacron:UFG
instname_str Universidade Federal de Goiás (UFG)
instacron_str UFG
institution UFG
reponame_str Ciência animal brasileira (Online)
collection Ciência animal brasileira (Online)
repository.name.fl_str_mv Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)
repository.mail.fl_str_mv ||revistacab@gmail.com
_version_ 1799874788733222912