Immunopathology of the murine experimental autoimmune encephalomyelitis mediated by T lymphocytes

Detalhes bibliográficos
Autor(a) principal: Gávio Silva, Adriana Karla
Data de Publicação: 2009
Outros Autores: de Paula, Márcio Luiz, Ferreira, Ana Paula
Tipo de documento: Artigo
Idioma: por
Título da fonte: HU Revista (Online)
Texto Completo: https://periodicos.ufjf.br/index.php/hurevista/article/view/236
Resumo: Multiple Sclerosis is a chronic, inflammatory and demyelinating disease of the Central Nervous System. Although its etiology is still unclear, it is supposed a CD4+ T Helper-1-mediated autoimmune disease. Experimental Autoimmune Encephalomyelitis (EAE) is an animal model to study Multiple Sclerosis. The characteristics of this model are inflammation and demyelination similar to Multiple Sclerosis. EAE allows to assess parameters such as CD4+ and CD8+ T lymphocytes, regulatory T lymphocytes, costimulatory molecules, chemokines and so on. The aim of this study was to make a bibliographic revision of the murine EAE immunopathology mediated by T cells. Keywords: Multiple Sclerosis. Experimental Autoimmune Encephalomyelitis.  T lymphocytes.
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spelling Immunopathology of the murine experimental autoimmune encephalomyelitis mediated by T lymphocytesImunopatologia da encefalomielite auto-imune experimental murina mediada por linfócitos TEsclerose Múltipla. Encefalomielite Auto-imune Experimental. linfócitos TMultiple Sclerosis is a chronic, inflammatory and demyelinating disease of the Central Nervous System. Although its etiology is still unclear, it is supposed a CD4+ T Helper-1-mediated autoimmune disease. Experimental Autoimmune Encephalomyelitis (EAE) is an animal model to study Multiple Sclerosis. The characteristics of this model are inflammation and demyelination similar to Multiple Sclerosis. EAE allows to assess parameters such as CD4+ and CD8+ T lymphocytes, regulatory T lymphocytes, costimulatory molecules, chemokines and so on. The aim of this study was to make a bibliographic revision of the murine EAE immunopathology mediated by T cells. Keywords: Multiple Sclerosis. Experimental Autoimmune Encephalomyelitis.  T lymphocytes.A Esclerose Múltipla é uma doença crônica, inflamatória e desmielinizante do Sistema Nervoso Central. Embora a sua etiologia seja, ainda, desconhecida, supõe-se tratar de uma doença auto-imune mediada por células T CD4+ com perfil Th1. A Encefalomielite Auto-imune Experimental (EAE) é um modelo animal para estudar a Esclerose Múltipla. As características deste modelo são inflamações e desmielinização, se assemelhando à Esclerose Múltipla. A EAE permite avaliar parâmetros tais como linfócitos T CD4+ e T CD8+, linfócitos T regulatórios, moléculas co-estimulatórias, quimiocinas e etc. O objetivo deste estudo foi fazer uma revisão bibliográfica da imunopatologia da EAE murina mediada por linfócitos T.Editora UFJF2009-03-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtRevLitPesquisa bibliográfica descritivaapplication/pdfapplication/mswordhttps://periodicos.ufjf.br/index.php/hurevista/article/view/236HU Revista; v. 34 n. 3 (2008)1982-80470103-3123reponame:HU Revista (Online)instname:Universidade Federal de Juiz de Fora (UFJF)instacron:UFJFporhttps://periodicos.ufjf.br/index.php/hurevista/article/view/236/157https://periodicos.ufjf.br/index.php/hurevista/article/view/236/14942Gávio Silva, Adriana Karlade Paula, Márcio LuizFerreira, Ana Paulainfo:eu-repo/semantics/openAccess2023-05-04T03:53:16Zoai:periodicos.ufjf.br:article/236Revistahttps://periodicos.ufjf.br/index.php/hurevistaPUBhttps://periodicos.ufjf.br/index.php/hurevista/oairevista.hurevista@ufjf.edu.br1982-80470103-3123opendoar:2023-05-04T03:53:16HU Revista (Online) - Universidade Federal de Juiz de Fora (UFJF)false
dc.title.none.fl_str_mv Immunopathology of the murine experimental autoimmune encephalomyelitis mediated by T lymphocytes
Imunopatologia da encefalomielite auto-imune experimental murina mediada por linfócitos T
title Immunopathology of the murine experimental autoimmune encephalomyelitis mediated by T lymphocytes
spellingShingle Immunopathology of the murine experimental autoimmune encephalomyelitis mediated by T lymphocytes
Gávio Silva, Adriana Karla
Esclerose Múltipla. Encefalomielite Auto-imune Experimental. linfócitos T
title_short Immunopathology of the murine experimental autoimmune encephalomyelitis mediated by T lymphocytes
title_full Immunopathology of the murine experimental autoimmune encephalomyelitis mediated by T lymphocytes
title_fullStr Immunopathology of the murine experimental autoimmune encephalomyelitis mediated by T lymphocytes
title_full_unstemmed Immunopathology of the murine experimental autoimmune encephalomyelitis mediated by T lymphocytes
title_sort Immunopathology of the murine experimental autoimmune encephalomyelitis mediated by T lymphocytes
author Gávio Silva, Adriana Karla
author_facet Gávio Silva, Adriana Karla
de Paula, Márcio Luiz
Ferreira, Ana Paula
author_role author
author2 de Paula, Márcio Luiz
Ferreira, Ana Paula
author2_role author
author
dc.contributor.author.fl_str_mv Gávio Silva, Adriana Karla
de Paula, Márcio Luiz
Ferreira, Ana Paula
dc.subject.por.fl_str_mv Esclerose Múltipla. Encefalomielite Auto-imune Experimental. linfócitos T
topic Esclerose Múltipla. Encefalomielite Auto-imune Experimental. linfócitos T
description Multiple Sclerosis is a chronic, inflammatory and demyelinating disease of the Central Nervous System. Although its etiology is still unclear, it is supposed a CD4+ T Helper-1-mediated autoimmune disease. Experimental Autoimmune Encephalomyelitis (EAE) is an animal model to study Multiple Sclerosis. The characteristics of this model are inflammation and demyelination similar to Multiple Sclerosis. EAE allows to assess parameters such as CD4+ and CD8+ T lymphocytes, regulatory T lymphocytes, costimulatory molecules, chemokines and so on. The aim of this study was to make a bibliographic revision of the murine EAE immunopathology mediated by T cells. Keywords: Multiple Sclerosis. Experimental Autoimmune Encephalomyelitis.  T lymphocytes.
publishDate 2009
dc.date.none.fl_str_mv 2009-03-06
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
ArtRevLit
Pesquisa bibliográfica descritiva
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.ufjf.br/index.php/hurevista/article/view/236
url https://periodicos.ufjf.br/index.php/hurevista/article/view/236
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.ufjf.br/index.php/hurevista/article/view/236/157
https://periodicos.ufjf.br/index.php/hurevista/article/view/236/14942
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/msword
dc.publisher.none.fl_str_mv Editora UFJF
publisher.none.fl_str_mv Editora UFJF
dc.source.none.fl_str_mv HU Revista; v. 34 n. 3 (2008)
1982-8047
0103-3123
reponame:HU Revista (Online)
instname:Universidade Federal de Juiz de Fora (UFJF)
instacron:UFJF
instname_str Universidade Federal de Juiz de Fora (UFJF)
instacron_str UFJF
institution UFJF
reponame_str HU Revista (Online)
collection HU Revista (Online)
repository.name.fl_str_mv HU Revista (Online) - Universidade Federal de Juiz de Fora (UFJF)
repository.mail.fl_str_mv revista.hurevista@ufjf.edu.br
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