Intracranial Dysgerminoma

Detalhes bibliográficos
Autor(a) principal: Ferreira, Adriana Souza Sérgio
Data de Publicação: 2010
Outros Autores: Lima, U-Thant Mendonça, Silva, Carlos Eduardo Amaral Pereira, Costa, Sandra Marcia Carvalho Ribeiro, Louzada, Cibelle Ferreira, Medanha, Sabrina Cristina Araújo
Tipo de documento: Artigo
Idioma: por
Título da fonte: HU Revista (Online)
Texto Completo: https://periodicos.ufjf.br/index.php/hurevista/article/view/637
Resumo: Intracranial Dysgerminoma is a rare extragonadal germ cell tumor which originates itself at a extragonadal site.  It represents approximately 3 percent of intracranial tumors in children under the age of 15. For unknown reasons, these tumors are more frequent in Asian countries, where they account for 12 percent of  intracranial neoplasms. They show a peak in incidence between 10 and 14 years of age with a male predominance. We have reported a case of a 19 year-old patient who had been showing signs of diplopia and transitory parestesia of the left hand. He took brain magnetic resonance which identified nodule injuries in the right mesencephalus  and in the bilateral thalamic region as well. The histologic diagnosis was delayed due to the use of corticoid which contributed to the injury reduction preventing  access to the biopsy. After the interruption of the corticotherapy and injury regrowth, a biopsy was performed with the confirmation, by means of immunohistochemistry, of a brain  disgerminoma. The patient was submitted to a craniospinal radiotherapy, and a new magnetic resonance indicated a complete answer to the treatment done.
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spelling Intracranial DysgerminomaDisgerminoma CerebralDisgerminoma. Neoplasias Embrionárias de Células Germinativas.Intracranial Dysgerminoma is a rare extragonadal germ cell tumor which originates itself at a extragonadal site.  It represents approximately 3 percent of intracranial tumors in children under the age of 15. For unknown reasons, these tumors are more frequent in Asian countries, where they account for 12 percent of  intracranial neoplasms. They show a peak in incidence between 10 and 14 years of age with a male predominance. We have reported a case of a 19 year-old patient who had been showing signs of diplopia and transitory parestesia of the left hand. He took brain magnetic resonance which identified nodule injuries in the right mesencephalus  and in the bilateral thalamic region as well. The histologic diagnosis was delayed due to the use of corticoid which contributed to the injury reduction preventing  access to the biopsy. After the interruption of the corticotherapy and injury regrowth, a biopsy was performed with the confirmation, by means of immunohistochemistry, of a brain  disgerminoma. The patient was submitted to a craniospinal radiotherapy, and a new magnetic resonance indicated a complete answer to the treatment done. Disgerminoma cerebral é um raro tumor de células germinativas que se origina em um sítio extragonadal. Representa aproximadamente 3% dos tumores intracranianos em crianças abaixo de 15 anos (STROTHER et al., 2002). Por razões ainda desconhecidas, esses tumores são mais frequentes em países asiáticos, onde perfazem 12% dos tumores intracranianos (KNIERIM et al., 2003). O pico de incidência do tumor está entre 10 e 14 anos, e a localização pineal é mais frequente nos homens, enquanto a supra-selar acomete mais as mulheres. Relato de caso de um paciente de 19 anos que há 2 anos apresentava diplopia e parestesia fugaz de mão esquerda. Realizou Ressonância Magnética do Crânio que identificou lesões nodulares no mesencéfalo à direita e em região talâmica bilateral. O diagnóstico histológico foi retardado em função do uso de corticóide, que promoveu uma redução da lesão impedindo acesso a biópsia. Após suspensão da corticoterapia e recrescimento das lesões, foi realizada biópsia com a confirmação, por imunohistoquímica, de um disgerminoma cerebral. O paciente foi submetido à radioterapia cranioespinhal, e uma nova ressonância magnética demonstrou resposta completa ao tratamento efetuado.Editora UFJF2010-02-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRelCasRelato de casoapplication/pdfapplication/mswordhttps://periodicos.ufjf.br/index.php/hurevista/article/view/637HU Revista; v. 35 n. 3 (2009)1982-80470103-3123reponame:HU Revista (Online)instname:Universidade Federal de Juiz de Fora (UFJF)instacron:UFJFporhttps://periodicos.ufjf.br/index.php/hurevista/article/view/637/260https://periodicos.ufjf.br/index.php/hurevista/article/view/637/15038Ferreira, Adriana Souza SérgioLima, U-Thant MendonçaSilva, Carlos Eduardo Amaral PereiraCosta, Sandra Marcia Carvalho RibeiroLouzada, Cibelle FerreiraMedanha, Sabrina Cristina Araújoinfo:eu-repo/semantics/openAccess2023-05-04T03:53:20Zoai:periodicos.ufjf.br:article/637Revistahttps://periodicos.ufjf.br/index.php/hurevistaPUBhttps://periodicos.ufjf.br/index.php/hurevista/oairevista.hurevista@ufjf.edu.br1982-80470103-3123opendoar:2023-05-04T03:53:20HU Revista (Online) - Universidade Federal de Juiz de Fora (UFJF)false
dc.title.none.fl_str_mv Intracranial Dysgerminoma
Disgerminoma Cerebral
title Intracranial Dysgerminoma
spellingShingle Intracranial Dysgerminoma
Ferreira, Adriana Souza Sérgio
Disgerminoma. Neoplasias Embrionárias de Células Germinativas.
title_short Intracranial Dysgerminoma
title_full Intracranial Dysgerminoma
title_fullStr Intracranial Dysgerminoma
title_full_unstemmed Intracranial Dysgerminoma
title_sort Intracranial Dysgerminoma
author Ferreira, Adriana Souza Sérgio
author_facet Ferreira, Adriana Souza Sérgio
Lima, U-Thant Mendonça
Silva, Carlos Eduardo Amaral Pereira
Costa, Sandra Marcia Carvalho Ribeiro
Louzada, Cibelle Ferreira
Medanha, Sabrina Cristina Araújo
author_role author
author2 Lima, U-Thant Mendonça
Silva, Carlos Eduardo Amaral Pereira
Costa, Sandra Marcia Carvalho Ribeiro
Louzada, Cibelle Ferreira
Medanha, Sabrina Cristina Araújo
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Ferreira, Adriana Souza Sérgio
Lima, U-Thant Mendonça
Silva, Carlos Eduardo Amaral Pereira
Costa, Sandra Marcia Carvalho Ribeiro
Louzada, Cibelle Ferreira
Medanha, Sabrina Cristina Araújo
dc.subject.por.fl_str_mv Disgerminoma. Neoplasias Embrionárias de Células Germinativas.
topic Disgerminoma. Neoplasias Embrionárias de Células Germinativas.
description Intracranial Dysgerminoma is a rare extragonadal germ cell tumor which originates itself at a extragonadal site.  It represents approximately 3 percent of intracranial tumors in children under the age of 15. For unknown reasons, these tumors are more frequent in Asian countries, where they account for 12 percent of  intracranial neoplasms. They show a peak in incidence between 10 and 14 years of age with a male predominance. We have reported a case of a 19 year-old patient who had been showing signs of diplopia and transitory parestesia of the left hand. He took brain magnetic resonance which identified nodule injuries in the right mesencephalus  and in the bilateral thalamic region as well. The histologic diagnosis was delayed due to the use of corticoid which contributed to the injury reduction preventing  access to the biopsy. After the interruption of the corticotherapy and injury regrowth, a biopsy was performed with the confirmation, by means of immunohistochemistry, of a brain  disgerminoma. The patient was submitted to a craniospinal radiotherapy, and a new magnetic resonance indicated a complete answer to the treatment done.
publishDate 2010
dc.date.none.fl_str_mv 2010-02-05
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv https://periodicos.ufjf.br/index.php/hurevista/article/view/637
url https://periodicos.ufjf.br/index.php/hurevista/article/view/637
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.ufjf.br/index.php/hurevista/article/view/637/260
https://periodicos.ufjf.br/index.php/hurevista/article/view/637/15038
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eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/msword
dc.publisher.none.fl_str_mv Editora UFJF
publisher.none.fl_str_mv Editora UFJF
dc.source.none.fl_str_mv HU Revista; v. 35 n. 3 (2009)
1982-8047
0103-3123
reponame:HU Revista (Online)
instname:Universidade Federal de Juiz de Fora (UFJF)
instacron:UFJF
instname_str Universidade Federal de Juiz de Fora (UFJF)
instacron_str UFJF
institution UFJF
reponame_str HU Revista (Online)
collection HU Revista (Online)
repository.name.fl_str_mv HU Revista (Online) - Universidade Federal de Juiz de Fora (UFJF)
repository.mail.fl_str_mv revista.hurevista@ufjf.edu.br
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