Use of antimicrobial photodynamic therapy for the treatment of oral injuries associated with Acquired Immunodeficiency Syndrome: case report.

• Autor(a) principal: Nunes Santos, Ana Paula
• Data de Publicação: 2024
• Outros Autores: Rodrigues Brasil, Aline, Guedes de Souza, Carolina, Pires Fonseca, Gabriele, Fonseca Lucinda, Leda Marília
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: HU Revista (Online)
• Texto Completo: https://periodicos.ufjf.br/index.php/hurevista/article/view/39977
• topic: Photochemotherapy; Dentistry; Acquired Immunodeficiency Syndrome; Oral Ulcer; Fotoquimioterapia; Odontologia; Síndrome da Imunodeficiência Adquirida; Úlceras Orais

Introduction: a common feature of human immunodeficiency virus (HIV) infection is the development of oral lesions and, among the most frequent, we can mention nonspecific ulcerations, such as necrotizing stomatitis. One of the therapeutic options for nonspecific ulcers is the use of antimicrobial photodynamic therapy (aPDT), which is effective in controlling microorganisms and in tissue repair. Objective: to report the use of aPDT in the treatment of oral lesions associated with Acquired Immunodeficiency Syndrome (AIDS). Case Report: a 32-year-old HIV-positive male patient complained of pain due to multiple ulcerated lesions in the oral cavity. The initial procedure included tooth brushing, prescription of chlorhexidine mouthwash and a session of aPDT (methylene blue-mediated photodynamic therapy for 10min), followed by application of red laser 9 J per point. It was shown to be effective in relieving pain and healing of lesions, however,  a second aPDT irradiation with a 4 J infrared laser session was performed in the painful lesions. After a third session a complete healing was observed and there was no need to continue this treatment. Conclusion: the aPDT was effective in the treatment of oral lesions associated with AIDS.