Prevalência de leveduras do gênero Candida isoladas de hemocultura de pacientes hospitalizados
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | HU Revista (Online) |
Texto Completo: | https://periodicos.ufjf.br/index.php/hurevista/article/view/40948 |
Resumo: | Introduction: Bloodstream infection (BSI) by yeasts has Candida as its main genus. The main species that cause candidemia in Brazil are Candida albicans, Candida parapsilosis and Candida tropicalis, and C. albicans referred as the most prevalent. However, in recent decades, the prevalence of non-albicans Candida species (NAC) has increased and especially the emergence of Candida auris, which have mechanisms of resistance to the most used antifungals, characterizing a scenario of global concern. Objective: To assess the prevalence of Candida spp. in blood cultures of hospitalized patients, as well as the prevalence of the most isolated species and their distribution by hospital sectors. Material and Methods: This is an observational and retrospective study, of positive blood cultures for Candida spp. of patients admitted to a teaching hospital in the city of Juiz de Fora, Minas Gerais, from January 2021 to December 2022. Results: Among 3262 blood cultures analyzed, 1059 (32.46%) of which were positive. Of these, 1008 (95.18%) had bacterial growth and 51 (4.82%) had Candida spp. divided into, 20 (39.22%) C. albicans and 31 (60.78%) NAC. Of the NAC isolated, 14 were C. tropicalis (45.16%), 10 C. parapsilosis (32.26%), 3 C. glabrata (9.68%), 2 Candida kefyr (6.45%) and 2 Candida lusitaniae (6.45%). Of the 51 Candida spp. isolates, 25 (49.02%) were in the intensive care unit (ICU), 11 (21.57%) in the operating room and 15 (29.41%) were in the wards. Conclusion: Candida albicans is the main species related to candidemia in hospitalized patients, but species from the NAC group have shown high prevalence in blood culture isolates, especially in ICU patients. |
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Prevalência de leveduras do gênero Candida isoladas de hemocultura de pacientes hospitalizadosCandidaCandidemiaSepseHemoculturaIntroduction: Bloodstream infection (BSI) by yeasts has Candida as its main genus. The main species that cause candidemia in Brazil are Candida albicans, Candida parapsilosis and Candida tropicalis, and C. albicans referred as the most prevalent. However, in recent decades, the prevalence of non-albicans Candida species (NAC) has increased and especially the emergence of Candida auris, which have mechanisms of resistance to the most used antifungals, characterizing a scenario of global concern. Objective: To assess the prevalence of Candida spp. in blood cultures of hospitalized patients, as well as the prevalence of the most isolated species and their distribution by hospital sectors. Material and Methods: This is an observational and retrospective study, of positive blood cultures for Candida spp. of patients admitted to a teaching hospital in the city of Juiz de Fora, Minas Gerais, from January 2021 to December 2022. Results: Among 3262 blood cultures analyzed, 1059 (32.46%) of which were positive. Of these, 1008 (95.18%) had bacterial growth and 51 (4.82%) had Candida spp. divided into, 20 (39.22%) C. albicans and 31 (60.78%) NAC. Of the NAC isolated, 14 were C. tropicalis (45.16%), 10 C. parapsilosis (32.26%), 3 C. glabrata (9.68%), 2 Candida kefyr (6.45%) and 2 Candida lusitaniae (6.45%). Of the 51 Candida spp. isolates, 25 (49.02%) were in the intensive care unit (ICU), 11 (21.57%) in the operating room and 15 (29.41%) were in the wards. Conclusion: Candida albicans is the main species related to candidemia in hospitalized patients, but species from the NAC group have shown high prevalence in blood culture isolates, especially in ICU patients.Introdução: A infecção da corrente sanguínea (ICS) por leveduras, tem como principal gênero a Candida. As principais espécies que causam a candidemia no Brasil são Candida albicans, Candida parapsilosis e Candida tropicalis, sendo a C. albicans a mais prevalente. Todavia, nas últimas décadas tem aumentado a prevalência de espécies de Candida não albicans (CNA) e principalmente a emergência de Candida auris, que possuem mecanismos de resistência aos antifúngicos mais usados, caracterizando um cenário de preocupação mundial. Objetivo: Avaliar a prevalência de candidemia e das principais espécies de Candida spp. isoladas de amostras de hemocultura e sua distribuição por setores de internação de um hospital de ensino. Material e Métodos: Trata-se de um estudo observacional e retrospectivo, em que foram analisadas, através de bancos de dados, hemoculturas positivas para Candida spp. de pacientes internados em um hospital de ensino da cidade de Juiz de Fora, Minas Gerais, no período de janeiro de 2021 a dezembro de 2022. Resultados: Foram analisadas 3.262 hemoculturas, sendo 1.059 (32,46%) positivas. Destas, 1.008 (95,18%) tiveram crescimento bacteriano e 51 (4,82%) tiveram crescimento de Candida spp. divididos em, 20 (39,22%) C. albicans e 31 (60,78%) CNA. Das CNA isolados, 14 foram C. tropicalis (45,16%), 10 C. parapsilosis (32,26%), 3 C. glabrata (9,68%), 2 Candida kefyr (6,45%) e 2 Candida lusitaniae (6,45%). Dos 51 isolados de Candida spp., 25 (49,02%) foram no centro de tratamento intensivo, 11 (21,57%) no bloco cirúrgico e 15 (29,41%) foram nas enfermarias. Conclusão: Candida albicans é a principal espécie relacionada a candidemia em pacientes hospitalizados, porém espécies do grupo CNA têm apresentado elevada prevalência em isolados de hemocultura, principalmente em pacientes de centro de tratamento intensivo.Editora UFJF2023-10-24info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtOrapplication/pdfhttps://periodicos.ufjf.br/index.php/hurevista/article/view/4094810.34019/1982-8047.2023.v49.40948HU Revista; v. 49 (2023); 1-81982-80470103-3123reponame:HU Revista (Online)instname:Universidade Federal de Juiz de Fora (UFJF)instacron:UFJFporhttps://periodicos.ufjf.br/index.php/hurevista/article/view/40948/26450Copyright (c) 2023 Luciana Wu, Laura Lovato Soldati, Patricia Guedes Garciahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessWu, Luciana Lavorato Soldati, LauraGarcia, Patricia Guedes2023-07-12T14:00:44Zoai:periodicos.ufjf.br:article/40948Revistahttps://periodicos.ufjf.br/index.php/hurevistaPUBhttps://periodicos.ufjf.br/index.php/hurevista/oairevista.hurevista@ufjf.edu.br1982-80470103-3123opendoar:2023-07-12T14:00:44HU Revista (Online) - Universidade Federal de Juiz de Fora (UFJF)false |
dc.title.none.fl_str_mv |
Prevalência de leveduras do gênero Candida isoladas de hemocultura de pacientes hospitalizados |
title |
Prevalência de leveduras do gênero Candida isoladas de hemocultura de pacientes hospitalizados |
spellingShingle |
Prevalência de leveduras do gênero Candida isoladas de hemocultura de pacientes hospitalizados Wu, Luciana Candida Candidemia Sepse Hemocultura |
title_short |
Prevalência de leveduras do gênero Candida isoladas de hemocultura de pacientes hospitalizados |
title_full |
Prevalência de leveduras do gênero Candida isoladas de hemocultura de pacientes hospitalizados |
title_fullStr |
Prevalência de leveduras do gênero Candida isoladas de hemocultura de pacientes hospitalizados |
title_full_unstemmed |
Prevalência de leveduras do gênero Candida isoladas de hemocultura de pacientes hospitalizados |
title_sort |
Prevalência de leveduras do gênero Candida isoladas de hemocultura de pacientes hospitalizados |
author |
Wu, Luciana |
author_facet |
Wu, Luciana Lavorato Soldati, Laura Garcia, Patricia Guedes |
author_role |
author |
author2 |
Lavorato Soldati, Laura Garcia, Patricia Guedes |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Wu, Luciana Lavorato Soldati, Laura Garcia, Patricia Guedes |
dc.subject.por.fl_str_mv |
Candida Candidemia Sepse Hemocultura |
topic |
Candida Candidemia Sepse Hemocultura |
description |
Introduction: Bloodstream infection (BSI) by yeasts has Candida as its main genus. The main species that cause candidemia in Brazil are Candida albicans, Candida parapsilosis and Candida tropicalis, and C. albicans referred as the most prevalent. However, in recent decades, the prevalence of non-albicans Candida species (NAC) has increased and especially the emergence of Candida auris, which have mechanisms of resistance to the most used antifungals, characterizing a scenario of global concern. Objective: To assess the prevalence of Candida spp. in blood cultures of hospitalized patients, as well as the prevalence of the most isolated species and their distribution by hospital sectors. Material and Methods: This is an observational and retrospective study, of positive blood cultures for Candida spp. of patients admitted to a teaching hospital in the city of Juiz de Fora, Minas Gerais, from January 2021 to December 2022. Results: Among 3262 blood cultures analyzed, 1059 (32.46%) of which were positive. Of these, 1008 (95.18%) had bacterial growth and 51 (4.82%) had Candida spp. divided into, 20 (39.22%) C. albicans and 31 (60.78%) NAC. Of the NAC isolated, 14 were C. tropicalis (45.16%), 10 C. parapsilosis (32.26%), 3 C. glabrata (9.68%), 2 Candida kefyr (6.45%) and 2 Candida lusitaniae (6.45%). Of the 51 Candida spp. isolates, 25 (49.02%) were in the intensive care unit (ICU), 11 (21.57%) in the operating room and 15 (29.41%) were in the wards. Conclusion: Candida albicans is the main species related to candidemia in hospitalized patients, but species from the NAC group have shown high prevalence in blood culture isolates, especially in ICU patients. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-10-24 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion ArtOr |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.ufjf.br/index.php/hurevista/article/view/40948 10.34019/1982-8047.2023.v49.40948 |
url |
https://periodicos.ufjf.br/index.php/hurevista/article/view/40948 |
identifier_str_mv |
10.34019/1982-8047.2023.v49.40948 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.ufjf.br/index.php/hurevista/article/view/40948/26450 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2023 Luciana Wu, Laura Lovato Soldati, Patricia Guedes Garcia https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2023 Luciana Wu, Laura Lovato Soldati, Patricia Guedes Garcia https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Editora UFJF |
publisher.none.fl_str_mv |
Editora UFJF |
dc.source.none.fl_str_mv |
HU Revista; v. 49 (2023); 1-8 1982-8047 0103-3123 reponame:HU Revista (Online) instname:Universidade Federal de Juiz de Fora (UFJF) instacron:UFJF |
instname_str |
Universidade Federal de Juiz de Fora (UFJF) |
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UFJF |
institution |
UFJF |
reponame_str |
HU Revista (Online) |
collection |
HU Revista (Online) |
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HU Revista (Online) - Universidade Federal de Juiz de Fora (UFJF) |
repository.mail.fl_str_mv |
revista.hurevista@ufjf.edu.br |
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