Lower production of IL-17A and increased susceptibility to Mycobacterium bovis in mice coinfected with Strongyloides venezuelensis
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2011 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFJF |
| Texto Completo: | http://dx.doi.org/10.1590/S0074-02762011000500015 https://repositorio.ufjf.br/jspui/handle/ufjf/8460 |
Resumo: | - |
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2019-01-15T14:12:56Z2019-01-112019-01-15T14:12:56Z20111065617619http://dx.doi.org/10.1590/S0074-02762011000500015https://repositorio.ufjf.br/jspui/handle/ufjf/8460-The presence of intestinal helminths can down-regulate the immune response required to control mycobacterial infection. BALB/c mice infected with Mycobacterium bovis following an infection with the intestinal helminth Strongyloides venezuelensis showed reduced interleukin-17A production by lung cells and increased bacterial burden. Also, small granulomas and a high accumulation of cells expressing the inhibitory molecule CTLA-4 were observed in the lung. These data suggest that intestinal helminth infection could have a detrimental effect on the control of tuberculosis (TB) and render coinfected individuals more susceptible to the development of TB.eng--BrasilMemórias do Instituto Oswaldo Cruz-M. bovis - SVenezuelensisCoinfectionIL17CTLA4TuberculosisLower production of IL-17A and increased susceptibility to Mycobacterium bovis in mice coinfected with Strongyloides venezuelensisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleDias, Alyria TeixeiraCastro, Sandra Bertelli Ribeiro deAlves, Caio César SouzaRezende, Alice BelleigoliRodrigues, Michele FernandesMachado, Rachel Rocha PinheiroFernandes, AdrianaCorrêa, Deborah NegrãoTeixeira, Henrique CoutoFerreira, Ana Paulainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFJFinstname:Universidade Federal de Juiz de Fora (UFJF)instacron:UFJFTHUMBNAILLower production of IL-17A and increased susceptibility to Mycobacterium.pdf.jpgLower production of IL-17A and increased susceptibility to Mycobacterium.pdf.jpgGenerated Thumbnailimage/jpeg1696https://repositorio.ufjf.br/jspui/bitstream/ufjf/8460/4/Lower%20production%20of%20IL-17A%20and%20increased%20susceptibility%20to%20Mycobacterium.pdf.jpg560130729c14441958faa33f90fb4a04MD54ORIGINALLower production of IL-17A and increased susceptibility to Mycobacterium.pdfLower production of IL-17A and increased susceptibility to Mycobacterium.pdfapplication/pdf937126https://repositorio.ufjf.br/jspui/bitstream/ufjf/8460/1/Lower%20production%20of%20IL-17A%20and%20increased%20susceptibility%20to%20Mycobacterium.pdf2d1c38dbd130c72e06831c4c0ac8f3faMD51LICENSElicense.txtlicense.txttext/plain; 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| dc.title.pt_BR.fl_str_mv |
Lower production of IL-17A and increased susceptibility to Mycobacterium bovis in mice coinfected with Strongyloides venezuelensis |
| title |
Lower production of IL-17A and increased susceptibility to Mycobacterium bovis in mice coinfected with Strongyloides venezuelensis |
| spellingShingle |
Lower production of IL-17A and increased susceptibility to Mycobacterium bovis in mice coinfected with Strongyloides venezuelensis Dias, Alyria Teixeira - M. bovis - S Venezuelensis Coinfection IL 17 CTLA 4 Tuberculosis |
| title_short |
Lower production of IL-17A and increased susceptibility to Mycobacterium bovis in mice coinfected with Strongyloides venezuelensis |
| title_full |
Lower production of IL-17A and increased susceptibility to Mycobacterium bovis in mice coinfected with Strongyloides venezuelensis |
| title_fullStr |
Lower production of IL-17A and increased susceptibility to Mycobacterium bovis in mice coinfected with Strongyloides venezuelensis |
| title_full_unstemmed |
Lower production of IL-17A and increased susceptibility to Mycobacterium bovis in mice coinfected with Strongyloides venezuelensis |
| title_sort |
Lower production of IL-17A and increased susceptibility to Mycobacterium bovis in mice coinfected with Strongyloides venezuelensis |
| author |
Dias, Alyria Teixeira |
| author_facet |
Dias, Alyria Teixeira Castro, Sandra Bertelli Ribeiro de Alves, Caio César Souza Rezende, Alice Belleigoli Rodrigues, Michele Fernandes Machado, Rachel Rocha Pinheiro Fernandes, Adriana Corrêa, Deborah Negrão Teixeira, Henrique Couto Ferreira, Ana Paula |
| author_role |
author |
| author2 |
Castro, Sandra Bertelli Ribeiro de Alves, Caio César Souza Rezende, Alice Belleigoli Rodrigues, Michele Fernandes Machado, Rachel Rocha Pinheiro Fernandes, Adriana Corrêa, Deborah Negrão Teixeira, Henrique Couto Ferreira, Ana Paula |
| author2_role |
author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Dias, Alyria Teixeira Castro, Sandra Bertelli Ribeiro de Alves, Caio César Souza Rezende, Alice Belleigoli Rodrigues, Michele Fernandes Machado, Rachel Rocha Pinheiro Fernandes, Adriana Corrêa, Deborah Negrão Teixeira, Henrique Couto Ferreira, Ana Paula |
| dc.subject.cnpq.fl_str_mv |
- |
| topic |
- M. bovis - S Venezuelensis Coinfection IL 17 CTLA 4 Tuberculosis |
| dc.subject.por.fl_str_mv |
M. bovis - S Venezuelensis Coinfection IL 17 CTLA 4 Tuberculosis |
| description |
- |
| publishDate |
2011 |
| dc.date.issued.fl_str_mv |
2011 |
| dc.date.accessioned.fl_str_mv |
2019-01-15T14:12:56Z |
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2019-01-11 2019-01-15T14:12:56Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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https://repositorio.ufjf.br/jspui/handle/ufjf/8460 |
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http://dx.doi.org/10.1590/S0074-02762011000500015 |
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http://dx.doi.org/10.1590/S0074-02762011000500015 https://repositorio.ufjf.br/jspui/handle/ufjf/8460 |
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eng |
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eng |
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Memórias do Instituto Oswaldo Cruz |
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openAccess |
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- |
| dc.publisher.initials.fl_str_mv |
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Brasil |
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